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Miraz Rahman

Dr Miraz Rahman

ORCID: 0000-0001-8566-8648

Scopus Author ID: 56232895400

Clinical Academic Group

Department

Research interests

Application of synthetic medicinal chemistry and chemical biology techniques to the design, synthesis and evaluation of novel anticancer and antibacterial agents. 

 

Current Projects

  • Antibiotic Resistance Breaker (ARB) technology.
  • Development of new classes of antibacterial agents against multidrug-resistant pathogens.
  • Development of new generation antifungal agents.
  • Development of chemoresistance breakers against cancer stem cells.
  • Development of Anticancer Agents (DNA Interactive and PROTAC).
  • Development of chemical tools (e.g., EPI, membrane probes, enzyme inhibitors etc.) to study antimicrobial resistance.
  • Development of orthosteric biased antagonists to P2Y1 for anti-inflammatory therapy.
  • The exploitation of anaplerotic node as a therapeutic target against Mycobacterium tuberculosis.
  • Development of new antibiofilm agents through repurposing of existing licensed drugs.

  • Identification of New Therapeutic Combinations for Clinical Trial against COVID-19 Through Repurposing of Drugs with Known Safety Profile.

  • Development of a Gram-negative membrane penetration rule.
  • Mechanistic evaluation of natural products from plant origin. 

 

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