King's College London

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Mitchell Lai

  1. Isoform-specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias

    Low, C. Y. B., Lee, J. H., Lim, F. T. W., Lee, C., Ballard, C., Francis, P. T., Lai, M. K. P. & Tan, M. G. K., 2020, (Accepted/In press) In: Brain Pathology.

    Research output: Contribution to journalArticlepeer-review

  2. Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration

    Chai, Y. L., Chong, J. R., Weng, J., Howlett, D., Halsey, A., Lee, J. H., Attems, J., Aarsland, D., Francis, P. T., Chen, C. P. & Lai, M. K. P., 17 Oct 2018, In: Brain Pathology.

    Research output: Contribution to journalArticlepeer-review

  3. Mitochondrial Translocase of the Outer Membrane Alterations May Underlie Dysfunctional Oxidative Phosphorylation in Alzheimer's Disease

    Chai, Y. L., Xing, H., Chong, J. R., Francis, P. T., Ballard, C. G., Chen, C. P. & Lai, M. K. P., 19 Dec 2017, In: JOURNAL OF ALZHEIMERS DISEASE. 61, 2, p. 793-801 9 p.

    Research output: Contribution to journalArticlepeer-review

  4. Assessing Autism in Adults: An Evaluation of the Developmental, Dimensional and Diagnostic Interview—Adult Version (3Di-Adult)

    Mandy, W., Clarke, K., McKenner, M., Strydom, A., Crabtree, J., Lai, M-C., Allison, C., Baron-Cohen, S. & Skuse, D., 7 Nov 2017, In: Journal of Autism and Developmental Disorders. p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

  5. An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

    Datta, A., Chai, Y. L., Tan, J. M., Lee, J. H., Francis, P. T., Chen, C. P., Sze, S. K. & Lai, M. K. P., 11 Aug 2017, In: Molecular brain. 10, 1, 1 p.

    Research output: Contribution to journalArticlepeer-review

  6. Sex differences in frontal lobe connectivity in adults with autism spectrum conditions

    Zeestraten, E. A., Gudbrandsen, M. C., Daly, E., de Schotten, M. T., Catani, M., Dell'Acqua, F., Lai, M-C., Ruigrok, A. N. V., Lombardo, M. V., Chakrabarti, B., Baron-Cohen, S., Ecker, C., Murphy, D. G. M., Craig, M. C., MRC AIMS consortium, Bolton, P. F., Catani, M., Daly, E. M., Deoni, S., Ecker, C. & 5 others, Happe, F., Johnston, P., Madden, A., Spain, D. & Murphy, C. M., 11 Apr 2017, In: Translational psychiatry. 7, 4, e1090.

    Research output: Contribution to journalArticlepeer-review

  7. Increased Transforming Growth Factor β2 in the Neocortex of Alzheimer's Disease and Dementia with Lewy Bodies is Correlated with Disease Severity and Soluble Aβ42 Load

    Chong, J. R., Chai, Y. L., Lee, J. H., Howlett, D. R., Attems, J., Ballard, C. G., Aarsland, D., Francis, P. T., Chen, C. P. & Lai, M. K. P., 12 Jan 2017, In: JOURNAL OF ALZHEIMERS DISEASE. 56, 1, p. 157-166

    Research output: Contribution to journalArticlepeer-review

  8. Muscarinic M1 Receptor Coupling to G-protein is Intact in Parkinson's Disease Dementia

    Lee, J. H., Francis, P. T., Ballard, C. G., Aarsland, D., Kalaria, R. N., Wong, P. T-H., Chen, C. P. & Lai, M. K. P., 19 Oct 2016, In: Journal of Parkinson's Disease. 6, 4, p. 733-739

    Research output: Contribution to journalArticlepeer-review

  9. Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementias

    Xing, H., Lim, Y-A., Chong, J. R., Lee, J. H., Aarsland, D., Ballard, C. G., Francis, P. T., Chen, C. P. & Lai, M. K. P., 8 Sep 2016, In: Molecular Brain Research. 9, 1, p. 84

    Research output: Contribution to journalArticlepeer-review

  10. Relationship Between Cortical Gyrification, White Matter Connectivity, and Autism Spectrum Disorder

    Ecker, C., Andrews, D., Dell'Acqua, F., Daly, E., Murphy, C., Catani, M., Thiebaut de Schotten, M., Baron-Cohen, S., Lai, M. C., Lombardo, M. V., Bullmore, E. T., Suckling, J., Williams, S., Jones, D. K., Chiocchetti, A., Murphy, D. G. M., MRC AIMS consortium & Bolton, P. F., Jul 2016, In: Cerebral cortex (New York, N.Y. : 1991). 26, 7, p. 3297-3309

    Research output: Contribution to journalArticlepeer-review

  11. Altered relaxin family receptors RXFP1 and RXFP3 in the neocortex of depressed Alzheimer's disease patients

    Lee, J. H., Koh, S. Q., Guadagna, S., Francis, P. T., Esiri, M. M., Chen, C. P., Wong, P. T. H., Dawe, G. S. & Lai, M. K. P., 1 Feb 2016, In: Psychopharmacology. 233, 4, p. 591-598 8 p.

    Research output: Contribution to journalArticlepeer-review

  12. An isoform-specific role of FynT tyrosine kinase in Alzheimer's disease

    Lee, C., Low, C. Y. B., Francis, P. T., Attems, J., Wong, P. T. H., Lai, M. K. P. & Tan, M. G. K., 1 Feb 2016, In: Journal of Neurochemistry. 136, 3, p. 637-650 14 p.

    Research output: Contribution to journalArticlepeer-review

  13. Differential alterations of neocortical GluN receptor subunits in patients with mixed subcortical ischemic vascular dementia and Alzheimer's disease

    Mohamed, N. E., Lee, J. H., Francis, P. T., Esiri, M. M., Chen, C. P. & Lai, M. K. P., 2015, In: JOURNAL OF ALZHEIMERS DISEASE. 44, 2, p. 431-437 7 p.

    Research output: Contribution to journalArticlepeer-review

  14. Correlation of magnetic resonance imaging parameters with clinical disability in multiple sclerosis: a preliminary study

    GRIMAUD, J., Barker, G., WANG, L., LAI, M., MACMANUS, DG., WEBB, SL., THOMPSON, AJ., MCDONALD, WI., TOFTS, PS. & MILLER, DH., 1999, In: Journal of Neurology. 246, 10, p. 961-967 7 p.

    Research output: Contribution to journalArticlepeer-review

  15. Serial magnetization transfer imaging to characterize the early evolution of new MS lesions

    SILVER, NC., LAI, M., SYMMS, MR., Barker, G., MCDONALD, WI. & MILLER, DH., 1 Sep 1998, In: Neurology. 51, 3, p. 758-764 7 p.

    Research output: Contribution to journalArticlepeer-review

  16. Quantitative techniques for lesion load measurement in multiple sclerosis: an assessment of the global threshold technique after non uniformity and histogram matching corrections

    MOLYNEUX, PD., WANG, L., LAI, M., Barker, G., TOFTS, PS., MOSELEY, IF. & MILLER, DH., Jan 1998, In: European Journal of Neurology. 5, 1, p. 55-60 6 p.

    Research output: Contribution to journalArticlepeer-review

  17. An oblique cylinder contrast-adjusted (OCCA) phantom to measure the accuracy of MRI brain lesion volume estimation schemes in multiple sclerosis

    TOFTS, PS., Barker, G., FILIPPI, M., GAWNECAIN, M. & LAI, M., 1997, In: Magnetic Resonance Imaging. 15, 2, p. 183-192 10 p.

    Research output: Contribution to journalArticlepeer-review

  18. Apparent diffusion coefficients in benign and secondary progressive multiple sclerosis by nuclear magnetic resonance

    HORSFIELD, MA., LAI, M., WEBB, SL., Barker, G., TOFTS, PS., TURNER, R., RUDGE, P. & MILLER, DH., Sep 1996, In: Magnetic Resonance in Medicine. 36, 3, p. 393-400 8 p.

    Research output: Contribution to journalArticlepeer-review

  19. Quantification of MRI lesion load in multiple sclerosis: A comparison of three computer-assisted techniques

    GRIMAUD, J., LAI, M., THORPE, J., ADELEINE, P., WANG, L., Barker, G., PLUMMER, DL., TOFTS, PS., MCDONALD, WI. & MILLER, DH., 1996, In: Magnetic Resonance Imaging. 14, 5, p. 495-505 11 p.

    Research output: Contribution to journalArticlepeer-review

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