Munther Hussain

2020

UPREGULATION OF MACROPHAGE ACTIVATION MARKERS IS ASSOCIATED WITH POOR OUTCOME IN PATIENTS WITH ACUTE LIVER FAILURE

Cavazza, A., Huang, X., Hussain, M., Mitry, R. R., Ma, Y., Antoniades, C. G., Lee, W. M., McPhail, M. J. & Karvellas, C. J., Nov 2020, In: Hepatology. 72, p. 143A-144A

Research output: Contribution to journal › Meeting Abstract › peer-review

2019

A randomized controlled trial of metformin on left ventricular hypertrophy in patients with coronary artery disease without diabetes: the MET-REMODEL trial

Mohan, M., Al-Talabany, S., McKinnie, A., Mordi, I. R., Singh, J. S. S., Gandy, S. J., Baig, F., Hussain, M. S., Bhalraam, U., Khan, F., Choy, A. M., Matthew, S., Houston, J. G., Struthers, A. D., George, J. & Lang, C. C., 2019, In: European Heart Journal. 40, 41, p. 3409-3417 9 p.

Research output: Contribution to journal › Article › peer-review

111 Citations (Scopus)

DIAGNOSTIC ROLE OF SERUM MATRIX METALLOPROTEINASE-7 IN DISTINGUISHING JUVENILE AUTOIMMUNE SCLEROSING CHOLANGITIS FROM AUTOIMMUNE HEPATITIS: A PILOT STUDY

Si, T., Hussain, M., Huang, X., Samyn, M., Ma, Y. & Hadzic, N., Oct 2019, In: Hepatology. 70, p. 1255A-1255A

Research output: Contribution to journal › Meeting Abstract › peer-review

2017

CD14 expression and microbial infection in bladder tumours

Mousa, H. M., Jassem, A. N. & Hussain, M. J., 1 Jan 2017, In: Journal of Biological Sciences. 17, 8, p. 394-399 6 p.

Research output: Contribution to journal › Article › peer-review

2015

Acute alcoholic hepatitis and cellular Th1 immune responses to alcohol dehydrogenase

Blackmore, L. J., Ryan, J. M., Huang, X., Hussain, M., Triantafyllou, E., Vergis, N., Manakkat Vijay, G., Antoniades, C. G., Thursz, M. R., Jassem, W., Vergani, D., Shawcross, D. L. & Ma, Y., 26 Feb 2015, In: Lancet. 385 , S1, p. S22-S22 1 p., 61.

Research output: Contribution to journal › Poster abstract › peer-review

Th-17 cells infiltrate the liver in human biliary atresia and are related to surgical outcome

Hill, R., Quaglia, A., Hussain, M., Hadzic, N., Mieli-vergani, G., Vergani, D. & Davenport, M., 1 Aug 2015, In: Journal of Pediatric Surgery. 50, 8, p. 1297-1303

Research output: Contribution to journal › Article › peer-review

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42 Citations (Scopus)

385 Downloads (Pure)

2013

Alcohol dehydrogenase-specific T-cell responses are associated with alcohol consumption in patients with alcohol-related cirrhosis

Lin, F., Taylor, N. J., Su, H., Huang, X., Hussain, M. J., Abeles, R. D., Blackmore, L., Zhou, Y., Ikbal, M. M., Heaton, N., Jassem, W., Shawcross, D. L., Vergani, D. & Ma, Y., Jul 2013, In: Hepatology. 58, 1, p. 314-324 11 p.

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

2012

Cytokine levels and profiles in children related to sickle cell disease and asthma status

Knight-Madden, J., Vergani, D., Patey, R., Sylvester, K., Hussain, M. J., Forrester, T. & Greenough, A., Jan 2012, In: Journal of Interferon and Cytokine Research. 32, 1, p. 1-5 5 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

High prevalence of food sensitisation in young children with liver disease: a clue to food allergy pathogenesis?

Brown, C., Haringman, N., Davies, C., Gore, C., Hussain, M., Mieli-Vergani, G., Vergani, D., Warner, J. O., Marks, S. D. & Boyle, R. J., Dec 2012, In: Pediatric Allergy and Immunology. 23, 8, p. 770-777 8 p.

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Immunohistochemical phenotyping of the inflammatory infiltrate in de novo autoimmune hepatitis after liver transplantation in children

Hadzic, N., Quaglia, A., Cotoi, C., Hussain, M. J., Brown, N., Vergani, D. & Mieli-Vergani, G., Aug 2012, In: PEDIATRIC TRANSPLANTATION. 16, 5, p. 501-510 10 p.

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

Antoniades, C. G., Quaglia, A., Taams, L. S., Mitry, R. R., Hussain, M., Abeles, R., Possamai, L. A., Bruce, M., McPhail, M., Starling, C., Wagner, B., Barnardo, A., Pomplun, S., Auzinger, G., Bernal, W., Heaton, N., Vergani, D., Thursz, M. R. & Wendon, J., Aug 2012, In: Hepatology. 56, 2, p. 735-746 12 p.

Research output: Contribution to journal › Article › peer-review

224 Citations (Scopus)

2011

Autoantigen-Specific Regulatory T Cells, a Potential Tool for Immune-Tolerance Reconstitution in Type-2 Autoimmune Hepatitis

Longhi, M. S., Hussain, M. J., Kwok, W. W., Mieli-Vergani, G., Ma, Y. & Vergani, D., Feb 2011, In: Hepatology. 53, 2, p. 536 - 547 12 p.

Research output: Contribution to journal › Article › peer-review

96 Citations (Scopus)

Severity of the compensatory anti-inflammatory response determined by monocyte HLA-DR expression may assist outcome prediction in cirrhosis

Berry, P. A., Antoniades, C. G., Carey, I., McPhail, M. J. W., Hussain, M. J., Davies, E. T., Wendon, J. A. & Vergani, D., Mar 2011, In: Intensive Care Medicine. 37, 3, p. 453 - 460 8 p.

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

2010

Admission levels and early changes in serum interleukin-10 are predictive of poor outcome in acute liver failure and decompensated cirrhosis

Berry, P. A., Antoniades, C. G., Hussain, M. J., McPhail, M. J. W., Bernal, W., Vergani, D. & Wendon, J. A., May 2010, In: LIVER INTERNATIONAL. 30, 5, p. 733 - 740 8 p.

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

A Multifaceted Imbalance of T Cells with Regulatory Function Characterizes Type 1 Autoimmune Hepatitis

Ferri, S., Longhi, M. S., De Molo, C., Lalanne, C., Muratori, P., Granito, A., Hussain, M. J., Ma, Y., Lenzi, M., Mieli-Vergani, G., Bianchi, F. B., Vergani, D. & Muratori, L., Sept 2010, In: Hepatology. 52, 3, p. 999 - 1007 9 p.

Research output: Contribution to journal › Article › peer-review

168 Citations (Scopus)

Arterial stiffening relates to arterial calcification but not to non-calcified atheroma as determined by multimodality imaging of the aorta

Cecelja, M., Hussain, M., Greil, G., Spector, T. D. & Chowienczyk, P., 2010, In: Journal of Human Hypertension. 24, 10, p. 693 - 693 1 p.

Research output: Contribution to journal › Meeting abstract

CYTOKINE BIOMARKER PROFILING IN ACETAMINOPHEN-INDUCED ACUTE LIVER FAILURE: IMPORTANCE OF MONOCYTE CHEMOTACTIC PROTEIN-1 IN PROGNOSIS AND HEPATIC ENCEPHALOPATHY

Antoniades, C. G., Bruce, M. J., McPhail, M., Rajaventhan, S., Berry, P. A., Hussain, M. J., Willars, C., Bernal, W., Auzinger, G. & Wendon, J., 2010, In: Hepatology. 52, 4, p. 1100A - 1100A

Research output: Contribution to journal › Meeting abstract

Liver infiltrating T-lymphocytes in autoimmune hepatitis have a combined TH1 and TH17 effector profile

Hussain, M. J., Baker, M., Longhi, M. S., Ma, Y., Mieli-Vergani, G. & Vergani, D., 2010, In: Immunology. 131, p. 149 - 150 2 p.

Research output: Contribution to journal › Meeting abstract

Reduced Neutrophil Function Persists 72 Hours Following Liver Transplantation Despite Normalization of Arterial Ammonia

Taylor, N., Abeles, R., Hussain, M., Yun, M., Wendon, J., O'Grady, J., Heaton, N. & Shawcross, D., 2010, In: Liver Transplantation. 16, 6, p. S223 - S223

Research output: Contribution to journal › Meeting abstract

Serum Levels of CK18 M30 and Leptin Are Useful Predictors of Steatohepatitis and Fibrosis in Paediatric NAFLD

Fitzpatrick, E., Mitry, R. R., Quaglia, A., Hussain, M. J., DeBruyne, R. & Dhawan, A., Oct 2010, In: Journal of Pediatric Gastroenterology and Nutrition. 51, 4, p. 500 - 506 7 p.

Research output: Contribution to journal › Article › peer-review

99 Citations (Scopus)

2009

CIRRHOSIS LEADS TO IMPAIRED NEUTROPHIL PHAGOCYTOSIS WHICH PARALLELS INCREASED IL-10 CONCENTRATION AND IS REVERSED FOLLOWING LIVER TRANSPLANTATION

Taylor, N. J., Ma, Y., Abeles, D., Hussain, M. J., Auzinger, G., Heneghan, M. A., O'Grady, J. G., Bernal, W., Vergani, D., Wendon, J. & Shawcross, D. L., 2009, In: Hepatology. 50, 4, p. 450A - 451A

Research output: Contribution to journal › Meeting abstract

European S3-guidelines on the systemic treatment of psoriasis vulgaris.

Pathirana, D., Ormerod, A., Saiag, P., Smith, C., Spuls, P., Nast, A., Barker, J., Bos, J., Burmester, G., Chimenti, S., Dubertret, L., Eberlein, B., Erdmann, R., Ferguson, J., Girolomoni, G., Gisondi, P., Giunta, A., Griffiths, C., Honigsmann, H. & Hussain, M. & 19 others, Jobling, R., Karvonen, S., Kemeny, L., Kopp, I., Leonardi, C., Maccarone, M., Menter, A., Mrowietz, U., Naldi, L., Nijsten, T., Ortonne, J., Orzechowski, H., Rantanen, T., Reich, K., Reytan, N., Richards, H., Thio, H., van de Kerkhof, P. & Rzany, B., Oct 2009, In: Journal of The European Academy of Dermatology and Venereology. 23, SUPPL. 2, p. 1 - 70 70 p.

Research output: Contribution to journal › Article › peer-review

631 Citations (Scopus)

INTRAHEPATIC CD25+CD122-TCR gamma delta T CELLS IN PATIENTS WITH AUTOIMMUNE HEPATITIS PRODUCE MORE IL-17 THAN IFN-gamma

Wang, P., Longhi, M. S., Hussain, M. J., Vara, R., Grammatikopoulos, T., Subramaniam, P., Mieli-Vergani, G., Vergani, D. & Ma, Y., 2009, In: Hepatology. 50, 4, p. 1014A - 1015A

Research output: Contribution to journal › Meeting abstract

MECHANISMS OF HEPATOCELLULAR DEATH IN CHILDREN WITH ACUTE LIVER FAILURE OF UNKNOWN AETIOLOGY

Mustafa, A., Mitry, R. R., Ngianga-Bakwin, K., Hussain, M. J. & Dhawan, A., 2009, In: Hepatology. 50, 4, p. 758A - 758A

Research output: Contribution to journal › Meeting abstract

NEUTROPHIL DYSFUNCTION IN ACUTE LIVER FAILURE DEFINES THOSE PATIENTS WHO HAVE A POOR PROGNOSIS AND IS REVERSED FOLLOWING LIVER TRANSPLANTATION

Taylor, N. J., Ma, Y., Abeles, D., Hussain, M. J., Auzinger, G., Vergani, D., Bernal, W., Wendon, J. & Shawcross, D. L., 2009, In: Hepatology. 50, 4, p. 423A - 423A

Research output: Contribution to journal › Meeting abstract

Vigorous Activation of Monocytes in Juvenile Autoimmune Liver Disease Escapes the Control of Regulatory T-Cells

Longhi, S., Mitry, R. R., Samyn, M., Scalori, A., Hussain, M. J., Quaglia, A., Mieli-Vergani, G., Ma, Y. & Vergani, D., Jul 2009, In: Hepatology. 50, 1, p. 130 - 142 13 p.

Research output: Contribution to journal › Article › peer-review

76 Citations (Scopus)

2008

CYP(2)D6-specific CD4(+)CD25(+) regulatory T-cells inhibit Th1 and Th17, but promote Th2 cytokine secretion in patients with autoimmune hepatitis type 2

Longhi, M. S., Hussain, M. J., Mieli-Vergani, G., Ma, Y. & Vergani, D., 2008, In: Immunology. 125, p. 119 - 119 1 p.

Research output: Contribution to journal › Meeting abstract

CYP2D6-SPECIFIC CD4+CD25+REGULATORY T-CELLS INHIBIT TH1 AND TH17, BUT PROMOTE TH2 CYTOKINE SECRETION IN PATIENTS WITH AUTOIMMUNE HEPATITIS TYPE 2

Longhi, M. S., Hussain, M. J., Mieli-Vergoni, G., Ma, Y. & Vergani, D., 2008, In: Hepatology. 48, 4, p. 421A - 421A

Research output: Contribution to journal › Meeting abstract

High frequency of anti-cardiolipin and anti-beta2-glycoprotein-1 positivity in paediatric liver transplant recipients developing vascular complications

Hadzic, N., Davies, E. T., Hussain, M., Kostaliva, J., Rela, M., Heaton, N. D., Vergani, D. & Mieli-Vergani, G., 2008, In: Journal of Hepatology. 48, p. 205 1 p.

Research output: Contribution to journal › Meeting abstract

INTERLEUKIN-10 IS PIVOTAL TO THE "DYSREGULATED" INFLAMMATORY RESPONSE OF ACUTE LIVER FAILURE

Antoniades, C. G., Berry, P. A., Carey, I., Longhi, S., Cross, T. J., Hussain, M. J., Quaglia, A., Wendon, J. & Vergani, D., 2008, In: Hepatology. 48, 4, p. 449A - 449A

Research output: Contribution to journal › Meeting abstract

RESPONSE TO PEGYLATED INTERFERON/RIBAVIRIN IN CHRONIC HEPATITIS C IN CHILDREN IS PREDICTED BY PRE-TREATMENT NUMBER OF ACTIVATED NATURAL KILLER (NK) CELLS

Carey, I., Cebecauerova, D., Bansal, S., Subra-Maniam, P., Hussain, M. J., Mytilinaiou, M., Mieli-Vergani, G. & Vergani, D., 2008, In: Hepatology. 48, 4, p. 321A - 321A

Research output: Contribution to journal › Meeting abstract

RESPONSE TO PEGYLATED INTERFERON/RIBAVIRIN IN CHRONIC HEPATITIS C IN CHILDREN IS PREDICTED BY PRE-TREATMENT NUMBER OF ACTIVATED NATURAL KILLER (NK) CELLS

Carey, I., Cebecauerova, D., Bansal, S., Subramaniam, P., Hussain, M. J., Mytilinaiou, M., Mieli-Vergani, G. & Vergani, D., 2008, In: Hepatology. 48, 4, p. 1030A - 1031A

Research output: Contribution to journal › Meeting abstract

The increasing prevalence of hepatitis delta virus (HDV) infection in South London

Cross, T. J. S., Rizzi, P., Horner, M., Jolly, A., Hussain, M. J., Smith, H. M., Vergani, D. & Harrison, P. M., Feb 2008, In: Journal of Medical Virology. 80, 2, p. 277 - 282 6 p.

Research output: Contribution to journal › Article › peer-review

165 Citations (Scopus)

2007

Actin-free gc globulin: A rapidly assessed biomarker of organ dysfunction in acute liver failure and cirrhosis

Antoniades, C. G., Berry, P. A., Bruce, M., Cross, T. J. S., Portal, A. J., Hussain, M. J., Bernal, W., Wendon, J. A. & Vergani, D., Sept 2007, In: Liver Transplantation. 13, 9, p. 1254 - 1261 8 p.

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Admission levels and early changes in serum IL-10 are associated with poor outcome in acute liver failure and acute-on-chronic liver failure

Berry, P. A., Antoniades, C. G., Bernal, W., Hussain, M., Auzinger, G., Sizer, E., Vergani, D. & Wendon, J., 2007, In: Hepatology. 46, 4, p. 857 1 p.

Research output: Contribution to journal › Meeting abstract

Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2

Longhi, M. S., Hussain, M. J., Bogdanos, D. P., Quaglia, A., Mieli-Vergani, G., Ma, Y. & Vergani, D., Aug 2007, In: Hepatology. 46, 2, p. 472 - 484 13 p.

Research output: Contribution to journal › Article › peer-review

125 Citations (Scopus)

HCV-specific production of IL-10 and IFN-gamma-inducible protein-10 (IP-10) levels predict treatment response to pegylated interferon and ribavirin in children with chronic hepatitis C infection

Carey, I., Mytilinaiou, M., Hussain, M., Bansal, S., Subramaniam, P., Horner, M., Longhi, M. S., Meda, F., Mieli-Vergani, G. & Vergani, D., 2007, In: Hepatology. 46, 4, p. 101 1 p.

Research output: Contribution to journal › Meeting abstract

103 Citations (Scopus)

2006

Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis.

Longhi, M., Hussain, M. J., Mitry, R. R., Arora, S. K., Mieli-Vergani, G., Vergani, D. & Ma, Y., 1 Apr 2006, In: Journal of Immunology. 176, 7, p. 4484 - 4491 8 p.

Research output: Contribution to journal › Article › peer-review

296 Citations (Scopus)

IL-10 producing monocytes in acute liver failure: Correlation with the systemic inflammatory response

Antoniades, C. G., Berry, P. A., Longhi, S., Davies, E. T., Cross, T. J., Hussain, M., Wendon, J. & Vergani, D., 2006, In: Hepatology. 44, 4, p. 468 1 p.

Research output: Contribution to journal › Meeting abstract

Immunohistochemical perforin staining allows differentiation between hepatitis C recurrence and rejection post-liver transplant

Quaglia, A., Hussain, M., Henegan, M., Portmann, B. & Vergani, D., 2006, In: Hepatology. 44, 4, p. 783 1 p.

Research output: Contribution to journal › Meeting abstract

Intrahepatic T-bet positive cells are more frequent in HCV/HIV coinfected than HCV monoinfected patients possibly accounting for the accelerated liver fibrosis progression in coinfected patients

Hussain, M., Almerighi, C., Mohsen, A., Bogdanos, D., Norris, S., Portmann, B. & Vergani, D., 2006, In: Hepatology. 44, 4, p. 302 1 p.

Research output: Contribution to journal › Meeting abstract

In vitro immunosuppressive effect of vitamin D3 in primary biliary cirrhosis

Almerighi, C., Bogdanos, D. P., Cholongitas, V., Carey, I., Meda, F., Hussain, M. J., Burroughs, A. K. & Vergani, D., 2006, In: Journal of Hepatology. 44, p. 626 1 p.

Research output: Contribution to journal › Meeting abstract

Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2

Ma, Y., Bogdanos, D. P., Hussain, M. J., Underhill, J., Bansal, S., Longhi, M. S., Cheeseman, P., Mieli-Vergani, G. & Vergani, D., Mar 2006, In: Gastroenterology. 130, 3, p. 868 - 882 15 p.

Research output: Contribution to journal › Article › peer-review

180 Citations (Scopus)

Reduced monocyte HLA-DR expression: A novel biomarker of disease severity and outcome in acetaminophen-induced acute liver failure

Antoniades, C. G., Berry, P. A., Davies, E. T., Hussain, M., Bernal, W., Vergani, D. & Wendon, J., Jul 2006, In: Hepatology. 44, 1, p. 34 - 43 10 p.

Research output: Contribution to journal › Article › peer-review

131 Citations (Scopus)

The prevalence of delta hepatitis (HDV) in a South London liver unit

Cross, T. J., Rizzi, P., Horner, M., Martin, K., Hussain, M. J., Vergani, D., Smith, H. M. & Harrison, P. M., 2006, In: Hepatology. 44, 4, p. 1315 1 p.

Research output: Contribution to journal › Meeting abstract

2005

Actin-free serum GC globulin levels closely mirror disease severity in both acute liver failure and chronic liver disease

Antoniades, C. G., Berry, P. A., Bruce, M., Cross, T. S., Hussain, M. & Wendon, J., 2005, In: Hepatology. 42, 4, p. 221A - 221A

Research output: Contribution to journal › Meeting abstract

Encephalopathy in cirrhosis is associated with reduced expression of the antigen presentation molecule HLA-DR on peripheral monocytes

Berry, P. A., Antoniades, C. G., Hussain, M. J., Davies, E. T. & Wendon, J., 2005, In: Hepatology. 42, 4, p. 240A - 241A

Research output: Contribution to journal › Meeting abstract

Munther Hussain

Research output

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