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Naomi Hartopp

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Research interests

Recently graduated Neuroscience PhD: Using induced pluripotent stem cell-derived motor neurons and post-mortem spinal cord tissue from control and amyotrophic lateral sclerosis (ALS) donors, my research has shown that interactions between endoplasmic reticulum (ER) and mitochondrial membranes are disrupted in human ALS, highlighting the interaction as a potential therapeutic target. Mass spectrometry analyses identified phosphorylation sites in ER-mitochondria tethering proteins and these sites were investigated as modulators of ER-mitochondria interactions using phospho-mimetic mutagenesis and in vitro assays.

 

Impact Case Study Manager: Researching the policy, healthcare and other public impacts of a variety of research projects across the Institute of Psychology, Psychiatry and Neuroscience including mental health, addictions science and molecular neuroscience.

 

Mutual Aid Researcher: A rapid response project researching the role of Covid-19 Community Mutual Aid groups in helping communities to navigate the impact of lockdown restrictions. Using both qualitative and quantitative research methods in a participatory action approach to investigate the different structures of these groups and their role in supporting communities.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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