Niamh Mullins

2022

Identifying the Common Genetic Basis of Antidepressant Response

GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2022, In: Biological Psychiatry Global Open Science. 2, 2, p. 115-126 12 p.

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Open Access

42 Citations (Scopus)

2021

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Nov 2021, In: Biological psychiatry. 90, 9, p. 611-620 10 p.

Research output: Contribution to journal › Article › peer-review

92 Citations (Scopus)

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

Martin, J., Asjadi, K., Hubbard, L., Kendall, K., Pardiñas, A. F., Jermy, B., Lewis, C. M., Baune, B. T., Boomsma, D. I., Hamilton, S. P., Lucae, S., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Mehta, D., Mors, O., Mullins, N., Penninx, B. W. J. H., Preisig, M., Rietschel, M., & 5 othersJones, I., Walters, J. T. R., Rice, F., Thapar, A. & O'Donovan, M., Sept 2021, In: PLoS ONE. 16, 9 September, e0248254.

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Open Access

6 Citations (Scopus)

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Blokland, G. A. M., Grove, J., Chen, C-Y., Cotsapas, C., Tobet, S., Handa, R., St Clair, D., Lencz, T., Mowry, B. J., Periyasamy, S., Cairns, M. J., Tooney, P. A., Wu, J. Q., Kelly, B., Kirov, G., Sullivan, P. F., Corvin, A., Riley, B. P., Esko, T., & 33 othersMilani, L., Jönsson, E. G., Palotie, A., Ehrenreich, H., Begemann, M., Steixner-Kumar, A., Sham, P. C., Iwata, N., Weinberger, D. R., Gejman, P. V., Sanders, A. R., Buxbaum, J. D., Rujescu, D., Giegling, I., Konte, B., Hartmann, A. M., Bramon, E., Murray, R. M., Pato, M. T., Lee, J., Melle, I., Molden, E., Ophoff, R. A., McQuillin, A., Bass, N. J., Adolfsson, R., Malhotra, A. K., Martin, N. G., Mullins, N., Breen, G., Lewis, C. M., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Young, A., 23 Mar 2021, (E-pub ahead of print) In: Biological psychiatry.

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

2020

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 15 Jul 2020, In: Biological psychiatry. 88, 2, p. 169-184 16 p.

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118 Citations (Scopus)

172 Downloads (Pure)

2019

Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2019, In: JAMA Psychiatry. 76, 4, p. 399-408 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

413 Citations (Scopus)

Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

eQTLGen Consortium, Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L., & 31 othersAgerbo, E., Akil, H., Albani, D., Alliey-Rodriguez, N., Als, T. D., Anjorin, A., Antilla, V., Awasthi, S., Badner, J. A., Bækvad-Hansen, M., Barchas, J. D., Bass, N., Bauer, M., Belliveau, R., Bergen, S. E., Pedersen, C. B., Bøen, E., Boks, M. P., Boocock, J., Budde, M., Bunney, W., Burmeister, M., Bybjerg-Grauholm, J., Byerley, W., Casas, M., de Jong, S., Kandaswamy, R., McGuffin, P., Mullins, N., Young, A. H. & Lewis, C. M., May 2019, In: Nature Genetics. 51, 5, p. 793-803 11 p.

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928 Citations (Scopus)

242 Downloads (Pure)

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., Anjorin, A., Corvin, A., Sanders, A. R., Forstner, A. J., Reif, A., Koller, A. C., Świątkowska, B., Baune, B. T., & 95 othersMüller-Myhsok, B., Penninx, B. W. J. H., Pato, C. N., Zai, C. C., Rujescu, D., Hougaard, D. M., Quested, D., Levinson, D. F., Binder, E. B., Byrne, E. M., Agerbo, E., Streit, F., Mayoral, F., Bellivier, F., Degenhardt, F., Breen, G. D., Morken, G., Turecki, G., Rouleau, G., Grabe, H. J., Volzke, H., Jones, I., Giegling, I., Agartz, I., Melle, I., Lawrence, J., Walters, J. T. R., Strohmaier, J., Shi, J., Hauser, J., Biernacka, J. M., Vincent, J. B., Kelsoe, J., Strauss, J. S., Lissowska, J., Pimm, J., Smoller, J. W., Guzman-Parra, J., Berger, K., Scott, L. J., Jones, L. A., Azevedo, M. H., Trzaskowski, M., Kogevinas, M., Rietschel, M., Boks, M. P., Ising, M., Grigoroiu-Serbanescu, M., Hamshere, M. L., Leboyer, M., Frye, M. A., Alda, M., Nordentoft, M., Boehnke, M., O'Donovan, M. C., Owen, M. J., Pato, M. T., Renteria, M. E., Wray, N. R., Bass, N., Craddock, N., Smeland, O. B., Andreassen, O. A., Mors, O., Gejman, P. V., Sklar, P., McGrath, P. J., Hoffmann, P., McGuffin, P., Lee, P. H., Mortensen, P. B., Kahn, R. S., Ophoff, R. A., Adolfsson, R., Van der Auwera Affiliations, S., Djurovic, S., Kloiber, S., Heilmann-Heimbach, S., Jamain, S., Hamilton, S. P., Mcelroy, S. L., Lucae, S., Cichon, S., Schulze, T. G., Hansen, T., Werge, T., Air, T. M., Nimgaonkar, V., Appadurai, V., Cahn, W., Milaneschi, Y., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C., 1 Aug 2019, In: The American Journal of Psychiatry. 176, 8, p. 651-660 10 p.

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165 Citations (Scopus)

144 Downloads (Pure)

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Wellcome Trust Case Control Consortium, Cross-Disorder Group of the Psychiatric Genomics Consortium, 23andMe Research Team, Psychosis Endophenotypes International Consortium, Lee, P. H., Anttila, V., Won, H., Feng, Y. C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., Arranz, M. J., Asherson, P., Kuntsi, J., Hansen, T. F., Reichenberg, A., Sandin, S., & 34 othersClarke, T. K., Coleman, J. R. I., Gaspar, H. A., Gordon, S. D., Kandaswamy, R., Lewis, C. M., Mullins, N., Schofield, P. R., Vincent, J. B., Baker, J. H., Davis, O. S. P., Helder, S. G., Roberts, M., Schmidt, U., Treasure, J., Walton, E., Howard, D., Smith, D. J., Uher, R., Collier, D. A., Kelly, B. J., Knight, J., McDonald, C., Murphy, K. C., Murray, R. M., Riley, B., Sham, P. C., van Os, J., Hedderly, T., Heyman, I., Woods, M., Breen, G., Walters, J. T. R. & Neale, B. M., 12 Dec 2019, In: Cell. 179, 7, p. 1469-1482.e11

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716 Citations (Scopus)

2018

DNA methylation and inflammation marker profiles associated with a history of depression

Crawford, B., Craig, Z., Mansell, G., White, I., Smith, A., Spaull, S., Imm, J., Hannon, E., Wood, A., Yaghootkar, H., Ji, Y., Mullins, N., Lewis, C. M., Mill, J. & Murphy, T. M., 22 May 2018, (E-pub ahead of print) In: Human Molecular Genetics. 27, 16, p. 2840-2850 11 p.

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., & 32 othersCai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F., 1 May 2018, In: Nature Genetics. 50, 5, p. 668-681

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1770 Citations (Scopus)

267 Downloads (Pure)

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Eley, T. C., Gaspar, H. A., McGuffin, P., Mullins, N., O'Reilly, P. F., Lewis, C. M. & Breen, G., 20 Dec 2018, In: PLoS ONE. 13, 12, e0209160.

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Open Access

12 Citations (Scopus)

2017

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A., & 5 othersVan der Auwera, S., Wray, N. R., Boomsma, D. I., Penninx, B. W. J. H. & Coleman, J., 1 Dec 2017, In: JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

151 Citations (Scopus)

Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD

Van der Auwera, S., Peyrot, W. J., Milaneschi, Y., Hertel, J., Baune, B., Breen, G., Byrne, E., Dunn, E. C., Fisher, H., Homuth, G., Levinson, D., Lewis, C., Mills, N., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rietschel, M., Ripke, S., Sullivan, P., & 6 othersTeumer, A., Völzke, H., Boomsma, D. I., Wray, N. R., Penninx, B. & Grabe, H., 8 Aug 2017, (Accepted/In press) In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 177, 1, p. 40-49

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Reproductive fitness and genetic risk of psychiatric disorders in the general population

Mullins, N., Ingason, A., Porter, H., Euesden, J., Gillett, A., Ólafsson, S., Gudbjartsson, D. F., Lewis, C. M., Sigurdsson, E., Saemundsen, E., Gudmundsson, Ó., Frigge, M. L., Kong, A., Helgason, A., Walters, G. B., Gustafsson, O., Stefansson, H. & Stefansson, K., 13 Jun 2017, In: Nature Communications. 8, 15833.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

Niamh Mullins

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