Nick Ashton

2025

Disentangling relationships between Alzheimer's disease plasma biomarkers and established biomarkers in patients of tertiary memory clinics

Bluma, M., Chiotis, K., Bucci, M., Savitcheva, I., Matton, A., Kivipelto, M., Jeromin, A., De Santis, G., Di Molfetta, G., Ashton, N. J., Blennow, K., Zetterberg, H. & Nordberg, A., Feb 2025, In: EBioMedicine. 112, 105504.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

2023

Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals

Öhrfelt, A., Benedet, A. L., Ashton, N. J., Kvartsberg, H., Vandijck, M., Weiner, M. W., Trojanowski, J. Q., Shaw, L. M., Zetterberg, H. & Blennow, K., 17 Jan 2023, In: Neurology. 100, 3, p. E275-E285

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer's disease in adults with Down syndrome

Mgaieth, F., Baksh, A., Startin, C., Hamburg, S., Hithersay, R., Pape, S., Zetterberg, H., Ashton, N., Tamayo Elizalde, M., Saini, F., Idris, M. & Strydom, A., Nov 2023, In: Alzheimer's & Dementia. 19, 11, p. 5129-5137 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

2022

Association of Plasma Biomarker Levels With Their CSF Concentration and the Number and Severity of Concussions in Professional Athletes

Shahim, P., Zetterberg, H., Simrén, J., Ashton, N. J., Norato, G., Schöll, M., Tegner, Y., Diaz-Arrastia, R. & Blennow, K., 26 Jul 2022, In: Neurology. 99, 4, p. E347-E354

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Association of Plasma p-tau181 and p-tau231 Concentrations with Cognitive Decline in Patients with Probable Dementia with Lewy Bodies

Gonzalez, M. C., Ashton, N. J., Gomes, B. F., Tovar-Rios, D. A., Blanc, F., Karikari, T. K., Mollenhauer, B., Pilotto, A., Lemstra, A., Paquet, C., Abdelnour, C., Kramberger, M. G., Bonanni, L., Vandenberghe, R., Hye, A., Blennow, K., Zetterberg, H. & Aarsland, D., 2022, In: JAMA Neurology. 79, 1, p. 32-37 6 p.

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses

Needham, E. J., Ren, A. L., Digby, R. J., Norton, E. J., Ebrahimi, S., Outtrim, J. G., Chatfield, D. A., Manktelow, A. E., Leibowitz, M. M., Newcombe, V. F. J., Doffinger, R., Barcenas-Morales, G., Fonseca, C., Taussig, M. J., Burnstein, R. M., Samanta, R. J., Dunai, C., Sithole, N., Ashton, N. J. & Zetterberg, H. & 20 others, Gisslén, M., Edén, A., Marklund, E., Openshaw, P. J. M., Dunning, J., Griffiths, M. J., Cavanagh, J., Breen, G., Irani, S. R., Elmer, A., Kingston, N., Summers, C., Bradley, J. R., Taams, L. S., Michael, B. D., Bullmore, E. T., Smith, K. G. C., Lyons, P. A., Coles, A. J. & Menon, D. K., 1 Sept 2022, In: Brain research. p. awac321

Research output: Contribution to journal › Article › peer-review

Open Access

File

56 Citations (Scopus)

138 Downloads (Pure)

Plasma Cystatin C Correlates with Plasma NfL Levels and Predicts Disease Progression in Parkinson's Disease

Imarisio, A., Pilotto, A., Garrafa, E., Conforti, F., Masciocchi, S., Turrone, R., Gipponi, S., Cottini, E., Rizzetti, M. C., Porrini, V., Gussago, C., Pizzi, M., Guadagni, F., Zetterberg, H., Ashton, N. J., Hye, A. & Padovani, A., 1 Jul 2022, In: Neurodegenerative Diseases. 21, 5-6, p. 109-116 8 p.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

2021

A genome-wide association study of plasma phosphorylated tau181

Lord, J., Zettergren, A., Ashton, N., Karkari, T., Benedet, A., Simren, J., Hye, A., Aarsland, D., Zetterberg, H., Blennow, K. & Proitsi, P., Oct 2021, In: Neurobiology of Aging. 106, p. 304.e1-304.e3

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

A multicentre validation study of the diagnostic value of plasma neurofilament light

Ashton, N. J., Janelidze, S., Al Khleifat, A., Leuzy, A., van der Ende, E. L., Karikari, T. K., Benedet, A. L., Pascoal, T. A., Lleó, A., Parnetti, L., Galimberti, D., Bonanni, L., Pilotto, A., Padovani, A., Lycke, J., Novakova, L., Axelsson, M., Velayudhan, L., Rabinovici, G. D. & Miller, B. & 21 others, Pariante, C., Nikkheslat, N., Resnick, S. M., Thambisetty, M., Schöll, M., Fernández-Eulate, G., Gil-Bea, F. J., López de Munain, A., Al-Chalabi, A., Rosa-Neto, P., Strydom, A., Svenningsson, P., Stomrud, E., Santillo, A., Aarsland, D., van Swieten, J. C., Palmqvist, S., Zetterberg, H., Blennow, K., Hye, A. & Hansson, O., 7 Jun 2021, In: Nature Communications. 12, 1, 3400.

Research output: Contribution to journal › Article › peer-review

Open Access

319 Citations (Scopus)

Plasma NfL, clinical subtypes and motor progression in Parkinson's disease

Pilotto, A., Imarisio, A., Conforti, F., Scalvini, A., Masciocchi, S., Nocivelli, S., Turrone, R., Gipponi, S., Cottini, E., Borroni, B., Rizzetti, M. C., Pizzi, M., Bonanni, L., Sturchio, A., Espay, A. J., Zetterberg, H., Ashton, N. J., Hye, A. & Padovani, A., Jun 2021, In: Parkinsonism and Related Disorders. 87, p. 41-47 7 p.

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age 70

Keshavan, A., Pannee, J., Karikari, T. K., Rodriguez, J. L., Ashton, N. J., Nicholas, J. M., Cash, D. M., Coath, W., Lane, C. A., Parker, T. D., Lu, K., Buchanan, S. M., Keuss, S. E., James, S. N., Murray-Smith, H., Wong, A., Barnes, A., Dickson, J. C., Heslegrave, A. & Portelius, E. & 5 others, Richards, M., Fox, N. C., Zetterberg, H., Blennow, K. & Schott, J. M., 1 Feb 2021, In: Brain. 144, 2, p. 434-449 16 p.

Research output: Contribution to journal › Article › peer-review

116 Citations (Scopus)

Replication study of plasma proteins relating to Alzheimer's pathology

Shi, L., Winchester, L. M., Westwood, S., Baird, A. L., Anand, S. N., Buckley, N. J., Hye, A., Ashton, N. J., Bos, I., Vos, S. J. B., Kate, M. T., Scheltens, P., Teunissen, C. E., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K. & Frisoni, G. B. & 32 others, Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lléo, A., Sala, I., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Legido-Quigley, C., Barkhof, F., Andreasson, U., Blennow, K., Zetterberg, H., Streffer, J., Lill, C. M., Bertram, L., Visser, P. J., Kolb, H. C., Narayan, V. A., Lovestone, S. & Nevado-Holgado, A. J., Sept 2021, In: Alzheimer's and Dementia. 17, 9, p. 1452-1464 13 p.

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease

for the AddNeuroMed consortium, Jul 2021, In: Alzheimer's and Dementia. 17, 7, p. 1145-1156 12 p.

Research output: Contribution to journal › Article › peer-review

225 Citations (Scopus)

2020

Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology

Shi, L., Winchester, L. M., Liu, B. Y., Killick, R., Ribe, E. M., Westwood, S., Baird, A. L., Buckley, N. J., Hong, S., Dobricic, V., Kilpert, F., Franke, A., Kiddle, S., Sattlecker, M., Dobson, R., Cuadrado, A., Hye, A., Ashton, N. J., Morgan, A. R. & Bos, I. & 47 others, Vos, S. J. B., Ten Kate, M., Scheltens, P., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lleó, A., Alcolea, D., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Teunissen, C. E., Freund-Levi, Y., Frölich, L., Legido-Quigley, C., Barkhof, F., Blennow, K., Rasmussen, K. L., Nordestgaard, B. G., Frikke-Schmidt, R., Nielsen, S. F., Soininen, H., Vellas, B., Kloszewska, I., Mecocci, P., Zetterberg, H., Morgan, B. P., Streffer, J., Visser, P. J., Bertram, L., Nevado-Holgado, A. J. & Lovestone, S., 2020, In: Journal of Alzheimer's Disease. 77, 3, p. 1353-1368 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected

for the ALFA Study, 7 Dec 2020, In: EMBO Molecular Medicine. 12, 12, e12921.

Research output: Contribution to journal › Article › peer-review

Open Access

262 Citations (Scopus)

Plasma transferrin and hemopexin are associated with altered Aβ uptake and cognitive decline in Alzheimer's disease pathology

Ashraf, A., Ashton, N. J., Chatterjee, P., Goozee, K., Shen, K.-K., Fripp, J., Ames, D., Rowe, C., Masters, C. L., Villemagne, V., Hye, A., Martins, R. N. & So, P.-W., 9 Jun 2020, 1 p.

Research output: Other contribution

File

23 Citations (Scopus)

95 Downloads (Pure)

Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-β Load

Chatterjee, P., Mohammadi, M., Goozee, K., Shah, T. M., Sohrabi, H. R., Dias, C. B., Shen, K., Asih, P. R., Dave, P., Pedrini, S., Ashton, N. J., Hye, A., Taddei, K., Lovejoy, D. B., Zetterberg, H., Blennow, K. & Martins, R. N., 1 Jan 2020, In: Journal of Alzheimer's disease : JAD. 76, 1, p. 291-301 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

Nick Ashton

Research output

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