King's College London

Research portal

Dr Nick Dand

  1. Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

    Mitchell, B. L., Saklatvala, J. R., Dand, N., Hagenbeek, F. A., Li, X., Min, J. L., Thomas, L., Bartels, M., Jan Hottenga, J., Lupton, M. K., Boomsma, D. I., Dong, X., Hveem, K., Løset, M., Martin, N. G., Barker, J. N., Han, J., Smith, C. H., Rentería, M. E. & Simpson, M. A., Dec 2022, In: Nature Communications. 13, 1, 702.

    Research output: Contribution to journalArticlepeer-review

  2. Biomarkers of disease progression in people with psoriasis: a scoping review

    Ramessur, R., Corbett, M., Marshall, D., Acencio, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Ostaszewski, M., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Ndlovu, M., Barker, J., & 3 othersSkov, L., Conrad, C. & Smith, C., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 481-493 13 p.

    Research output: Contribution to journalReview articlepeer-review

  3. Biomarkers of systemic treatment response in people with psoriasis: a scoping review

    Corbett, M., Ramessur, R., Marshall, D., Acencio, M., Ostaszewski, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Barker, J., Ndlovu, M., & 3 othersConrad, C., Skov, L. & Smith, C., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 494-506 13 p.

    Research output: Contribution to journalArticlepeer-review

  4. Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling

    the BADBIR Study Group & the BSTOP study group, Sep 2022, In: Arthritis and Rheumatology. 74, 9, p. 1535-1543 9 p.

    Research output: Contribution to journalArticlepeer-review

  5. Vaccine hesitancy and access to psoriasis care during the COVID-19 pandemic: findings from a global patient-reported cross-sectional survey

    PsoProtect study group, Bechman, K., Cook, E. S., Dand, N., Yiu, Z. Z. N., Tsakok, T., Meynell, F., Coker, B., Vincent, A., Bachelez, H., Barbosa, I., Brown, M. A., Capon, F., Contreras, C. R., De La Cruz, C., Di Meglio, P., Gisondi, P., Jullien, D., Kelly, J., Lambert, J., & 20 othersLancelot, C., Langan, S. M., Mason, K. J., McAteer, H., Moorhead, L., Naldi, L., Norton, S., Puig, L., Spuls, P. I., Torres, T., Urmston, D., Vesty, A., Warren, R. B., Waweru, H., Weinman, J., Griffiths, C. M., Barker, J. N., Smith, C. H., Galloway, J. B. & Mahil, S. K., Aug 2022, In: The British journal of dermatology. 187, 2, p. 254-256 3 p.

    Research output: Contribution to journalArticlepeer-review

  6. Differences in Clinical Features and Comorbid Burden between HLA-C∗06:02 Carrier Groups in >9,000 People with Psoriasis

    BADBIR & BSTOP Study Groups, Jun 2022, In: Journal of Investigative Dermatology. 142, 6, p. 1617-1628.e10

    Research output: Contribution to journalArticlepeer-review

  7. Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK

    Rayinda, T., McSweeney, S. M., Dand, N., Fenton, D. A., McGrath, J. A. & Tziotzios, C., Jan 2022, In: British Journal of Dermatology. 186, 1, p. 195-197 3 p.

    Research output: Contribution to journalLetterpeer-review

  8. Application of information theoretic feature selection and machine learning methods for the development of genetic risk prediction models

    BADBIR Study Group & BSTOP study group, Dec 2021, In: Scientific Reports. 11, 1, 23335.

    Research output: Contribution to journalArticlepeer-review

  9. Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

    Andres Ejarque, R., Ale, H. B. A., Grys, K., Tosi, I., Solanky, S., Ainali, C., Catak, Z., Sreeneebus, H., Saklatvala, J., Dand, N., de Rinaldis, E., Chapman, A., Nestle, F., Barnes, M. R., Richard, W., Reynolds, N. J., Griffiths, C., Barker, J., Smith, C., Di Meglio, P., & 1 othersCOnsortium, PSORT., Dec 2021, In: Nature Communications. 12, 1, p. 4741 1 p., 4741.

    Research output: Contribution to journalArticlepeer-review

  10. Genome-wide scan for structural variation underlying psoriasis

    Dand, N., 22 Nov 2021, (E-pub ahead of print) In: British Journal of Dermatology.

    Research output: Contribution to journalComment/debatepeer-review

  11. DIFFERENCES IN CLINICAL FEATURES AND COMORBID BURDEN BETWEEN HLA-C*06:02 CARRIER GROUPS IN MORE THAN 9,000 PEOPLE WITH PSORIASIS

    Douroudis, K., Ramessur, R., Biscaia De Andrade Barbosa, I., Baudry, D., Duckworth, M., Angit, C., Capon, F., Chung, R., Curtis, C., DiMeglio, P., Goudling, J., Griffiths, C., Lee, S., Mahil, S., Parslew, R., Reynolds, N., Shipman, A., warren, R., Yiu, Z., Simpson, M., & 3 othersBarker, J., Dand, N. & Smith, C., 21 Nov 2021, In: Journal of Investigative Dermatology.

    Research output: Contribution to journalArticlepeer-review

  12. The BIOMarkers in Atopic Dermatitis and Psoriasis (BIOMAP) glossary: developing a lingua franca to facilitate data harmonization and cross-cohort analyses

    the BIOMAP consortium, Nov 2021, In: British Journal of Dermatology. 185, 5, p. 1066-1069 4 p.

    Research output: Contribution to journalLetterpeer-review

  13. Association between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death among Patients with Immune-Mediated Inflammatory Disease and COVID-19

    Izadi, Z., Brenner, E. J., Mahil, S. K., Dand, N., Yiu, Z. Z. N., Yates, M., Ungaro, R. C., Zhang, X., Agrawal, M., Colombel, J. F., Gianfrancesco, M. A., Hyrich, K. L., Strangfeld, A., Carmona, L., Mateus, E. F., Lawson-Tovey, S., Klingberg, E., Cuomo, G., Caprioli, M., Cruz-Machado, A. R., & 45 othersMazeda Pereira, A. C., Hasseli, R., Pfeil, A., Lorenz, H. M., Hoyer, B. F., Trupin, L., Rush, S., Katz, P., Schmajuk, G., Jacobsohn, L., Seet, A. M., Al Emadi, S., Wise, L., Gilbert, E. L., Duarte-García, A., Valenzuela-Almada, M. O., Isnardi, C. A., Quintana, R., Soriano, E. R., Hsu, T. Y. T., D'Silva, K. M., Sparks, J. A., Patel, N. J., Xavier, R. M., Marques, C. D. L., Kakehasi, A. M., Flipo, R. M., Claudepierre, P., Cantagrel, A., Goupille, P., Wallace, Z. S., Bhana, S., Costello, W., Grainger, R., Hausmann, J. S., Liew, J. W., Sirotich, E., Sufka, P., Robinson, P. C., Machado, P. M., Griffiths, C. E. M., Barker, J. N., Smith, C. H., Yazdany, J. & Kappelman, M. D., 1 Oct 2021, In: JAMA Network open. 4, 10, p. e2129639

    Research output: Contribution to journalArticlepeer-review

  14. Defining trajectories of response in patients with psoriasis treated with biologic therapies

    the BADBIR Study Group & the PSORT Consortium, Oct 2021, In: British Journal of Dermatology. 185, 4, p. 825-835 11 p.

    Research output: Contribution to journalArticlepeer-review

  15. Describing the burden of the COVID-19 pandemic in people with psoriasis: findings from a global cross-sectional study

    PsoProtect study group, Oct 2021, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 35, 10, p. e636-e640

    Research output: Contribution to journalLetterpeer-review

  16. Factors associated with adverse COVID-19 outcomes in patients with psoriasis - insights from a global registry-based study

    PsoProtect study group, Jan 2021, In: Journal of Allergy and Clinical Immunology. 147, 1, p. 60-71 12 p.

    Research output: Contribution to journalArticlepeer-review

  17. Frontal fibrosing alopecia: a descriptive cross-sectional study of 711 cases in female patients from the UK

    McSweeney, S. M., Christou, E. A. A., Dand, N., Boalch, A., Holmes, S., Harries, M., Palamaras, I., Cunningham, F., Parkins, G., Kaur, M., Farrant, P., McDonagh, A., Messenger, A., Jones, J., Jolliffe, V., Ali, I., Ardern-Jones, M., Mitchell, C., Burrows, N., Atkar, R., & 25 othersBanfield, C., Alexandroff, A., Champagne, C., Cooper, H. L., Patel, G. K., Macbeth, A., Page, M., Bryden, A., Mowbray, M., Wahie, S., Armstrong, K., Cooke, N., Goodfield, M., Man, I., de Berker, D., Dunnil, G., Takwale, A., Rao, A., Siah, T. W., Sinclair, R., Wade, M. S., Bhargava, K., Fenton, D. A., McGrath, J. A. & Tziotzios, C., Dec 2020, In: British Journal of Dermatology. 183, 6, p. 1136-1138 3 p.

    Research output: Contribution to journalLetterpeer-review

  18. Association of Clinical and Demographic Factors With the Severity of Palmoplantar Pustulosis: Findings from the APRICOT, PLUM and ERASPEN consortia

    ERASPEN consortium and the APRICOT and PLUM study team, Nov 2020, In: JAMA dermatology. 156, 11, p. 1216-1222 7 p.

    Research output: Contribution to journalArticlepeer-review

  19. Clinical Impact of Antibodies against Ustekinumab in Psoriasis: An Observational, Cross-Sectional, Multicenter Study

    BADBIR, BSTOP Study Groups & PSORT consortium, Nov 2020, In: Journal of Investigative Dermatology. 140, 11, p. 2129-2137 9 p.

    Research output: Contribution to journalArticlepeer-review

  20. Global reporting of cases of COVID-19 in psoriasis and atopic dermatitis: an opportunity to inform care during a pandemic

    The Secure-AD, PsoPROTECT study groups, 1 Aug 2020, In: British Journal of Dermatology. 183, 2, p. 404-406 3 p.

    Research output: Contribution to journalLetterpeer-review

  21. Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study

    BADBIR Study Group, the BSTOP Study Group, the PSORT Consortium, Pan, S., Tsakok, T., Dand, N., Lonsdale, D. O., Loeff, F. C., Bloem, K., de Vries, A., Baudry, D., Duckworth, M., Mahil, S., Pushpa-Rajah, A., Russell, A., Alsharqi, A., Becher, G., Murphy, R., Wahie, S., Wright, A., Griffiths, C. E. M., Reynolds, N. J., & 6 othersBarker, J., Warren, R. B., David Burden, A., Rispens, T., Standing, J. F. & Smith, C. H., 1 Mar 2020, In: Clinical and Translational Science. 13, 2, p. 400-409 10 p.

    Research output: Contribution to journalArticlepeer-review

  22. Psoriasis and Genetics

    Dand, N., Mahil, S. K., Capon, F., Smith, C. H., Simpson, M. A. & Barker, J. N., 30 Jan 2020, In: Acta Dermato-Venereologica. 100, 100-year theme: Psoriasis, p. 54-64 11 p., adv00030.

    Research output: Contribution to journalReview articlepeer-review

  23. Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 15 Oct 2019, In: Human Molecular Genetics. 28, 20, p. 3498-3513 16 p.

    Research output: Contribution to journalArticlepeer-review

  24. Psoriasis treat to target: defining outcomes in psoriasis using data from a real world, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR)

    BADBIR study group and the PSORT consortium, Mahil, S. K., Wilson, N., Dand, N., Reynolds, N. J., Griffiths, C. E. M., Emsley, R., Marsden, A., Evans, I., Warren, R. B., Stocken, D., Barker, J. N., Burden, A. D. & Smith, C. H., 8 Jul 2019, (E-pub ahead of print) In: British Journal of Dermatology.

    Research output: Contribution to journalArticlepeer-review

  25. HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis

    Dand, N., Duckworth, M., Baudry, D., Russell, A., Curtis, C. J., Lee, S. H., Evans, I., Mason, K. J., Alsharqi, A., Becher, G., Burden, A. D., Goodwin, R. G., McKenna, K., Murphy, R., Perera, G. K., Rotarescu, R., Wahie, S., Wright, A., Reynolds, N. J., Warren, R. B., & 4 othersGriffiths, C. E. M., Smith, C. H., Simpson, M. A. & Barker, J. N., Jun 2019, In: Journal of Allergy and Clinical Immunology. 143, 6, p. 2120-2130

    Research output: Contribution to journalArticlepeer-review

  26. Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02

    Tziotzios, C., Petridis, C., Dand, N., Ainali, C., Saklatvala, J. R., Pullabhatla, V., Onoufriadis, A., Pramanik, R., Baudry, D., Lee, S. H., Wood, K., Liu, L., Seegobin, S., Michelotti, G. A., Lwin, S. M., Christou, E. A. A., Curtis, C. J., de Rinaldis, E., Saxena, A., Holmes, S., & 54 othersHarries, M., Palamaras, I., Cunningham, F., Parkins, G., Kaur, M., Farrant, P., McDonagh, A., Messenger, A., Jones, J., Jolliffe, V., Ali, I., Ardern-Jones, M., Mitchell, C., Burrows, N., Atkar, R., Banfield, C., Alexandroff, A., Champagne, C., Cooper, H. L., Vañó-Galván, S., Molina-Ruiz, A. M., Perez, N. O., Patel, G. K., Macbeth, A., Page, M., Bryden, A., Mowbray, M., Wahie, S., Armstrong, K., Cooke, N., Goodfield, M., Man, I., de Berker, D., Dunnill, G., Takwale, A., Rao, A., Siah, T-W., Sinclair, R., Wade, M. S., Dlova, N. C., Setterfield, J., Lewis, F., Bhargava, K., Kirkpatrick, N., Estivill, X., Stefanato, C. M., Flohr, C., Spector, T., Watt, F. M., Smith, C. H., Barker, J. N., Fenton, D. A., Simpson, M. A. & McGrath, J. A., 8 Mar 2019, In: Nature Communications. 10, 1, 9 p., 1150.

    Research output: Contribution to journalArticlepeer-review

  27. Defining the therapeutic range for adalimumab and predicting response in psoriasis: a multicenter prospective observational cohort study

    Wilkinson, N., Tsakok, T., Dand, N., Bloem, K., Duckworth, M., Baudry, D., Pushpa-Rajah, A., Griffiths, C. EM., Reynolds, N. J., Barker, J., Warren, R. B., Burden, A. D., Rispens, T., Stocken, D. & Smith, C., 1 Jan 2019, In: Journal of Investigative Dermatology. 139, 1, p. 115-123 9 p.

    Research output: Contribution to journalArticlepeer-review

  28. Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

    Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, 1 Jan 2019, In: Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticlepeer-review

  29. Association of Serum Ustekinumab Levels with Clinical Response in Psoriasis

    Tsakok, T., Wilson, N., Dand, N., Loeff, F. C., Bloem, K., Baudry, D., Duckworth, M., Pan, S., Pushpa-Rajah, A., Standing, J. F., De Vries, A., Alsharqi, A., Becher, G., Murphy, R., Wahie, S., Wright, A., Griffiths, C. E. M., Reynolds, N. J., Barker, J., Warren, R. B., & 4 othersBurden, A. D., Rispens, T., Stocken, D. & Smith, C., 2019, In: JAMA dermatology. 155, 11, p. 1235-1243 9 p.

    Research output: Contribution to journalArticlepeer-review

  30. Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne

    The Acne Genetic Study Group, Petridis, C., Navarini, A. A., Dand, N., Saklatvala, J., Baudry, D., Duckworth, M., Allen, M. H., Curtis, C. J., Lee, S. H., Burden, A. D., Layton, A., Bataille, V., Pink, A. E., Alexandroff, A., Anstey, A., Azad, J., Aziz, O., Burrows, N., Butt, A., & 37 othersCartwright, P., Chapman, A., Clayton, T. H., Cliff, S., Cutler, T., Daly, B., Darvay, A., DeGiovanni, C., Downs, A., Dwyer, C., English, J., Ferguson, A., Fleming, C., Fraser-Andrews, E., Goodfield, M., Grattan, C. E., Hempel, H., Hood, S., Hughes, B., Ladoyanni, E., Lyon, C., Mahmud, A., Malik, M., Mallon, E., Meggitt, S., Messenger, A., Moosa, Y., Munn, S., Ormerod, A., Rallan, D., Ross, J., McGrath, J. A., Barker, J. N. W. N., Smith, C. H., Spector, T. D., Barker, J. N. & Simpson, M. A., 12 Dec 2018, In: Nature Communications. 9, 1, 5075.

    Research output: Contribution to journalArticlepeer-review

  31. Clinical and genetic differences between pustular psoriasis subtypes

    Twelves, S., Mostafa, A., Dand, N., Burri, E., Farkas, K., Wilson, R., Cooper, H. L., Irvine, A. D., Oon, H. H., Kingo, K., Köks, S., Mrowietz, U., Puig, L., Reynolds, N., Sern-Ting Tan, E., Tanew, A., Torz, K., Trattner, H., Valentine, M., Wahie, S., & 11 othersWarren, R. B., Wright, A., Bata-Csörgő, Z., Szell, M., Griffiths, C. EM., Burden, A. D., Choon, S-E., Smith, C. H., Barker, J. N., Navarini, A. A. & Capon, F., 31 Jul 2018, In: Journal of Allergy and Clinical Immunology. 143, 3, p. 1021-1026

    Research output: Contribution to journalArticlepeer-review

  32. APPLICATION OF MACHINE LEARNING METHODS FOR PREDICTION MODELLING OF PSORIATIC ARTHRITIS IN PATIENTS WITH PSORIASIS

    Jalali-najafabadi, F., Dand, N., Ho, P., Smith, C. H., Barker, J. N., McHugh, N., Warren, R. B., Barton, A. & Bowes, J., Jun 2018, In: Annals of the rheumatic diseases. 77, p. 232-233

    Research output: Contribution to journalMeeting Abstractpeer-review

  33. Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

    Dand, N., Mucha, S., Tsoi, L. C., Mahil, S. K., Stuart, P. E., Arnold, A., Baurecht, H., Burden, A. D., Duffin, K. C., Chandran, V., Curtis, C. J., Das, S., Ellinghaus, D., Ellinghaus, E., Enerback, C., Esko, T., Gladman, D. D., Griffiths, C. E. M., Gudjonsson, J. E., Hoffman, P., & 34 othersHomuth, G., Hüffmeier, U., Krueger, G. G., Laudes, M., Lee, S. H., Lieb, W., Lim, H. W., Löhr, S., Mrowietz, U., Müller-Nurayid, M., Nöthen, M., Peters, A., Rahman, P., Reis, A., Reynolds, N. J., Rodriguez, E., Schmidt, C. O., Spain, S. L., Strauch, K., Tejasvi, T., Voorhees, J. J., Warren, R. B., Weichenthal, M., Weidinger, S., Zawistowski, M., Nair, R. P., Capon, F., Smith, C. H., Trembath, R. C., Abecasis, G. R., Elder, J. T., Franke, A., Simpson, M. A. & Barker, J. N., 1 Nov 2017, In: Human Molecular Genetics. 26, 21, p. 4301-4313

    Research output: Contribution to journalArticlepeer-review

  34. Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis

    Bowes, J., Ashcroft, J., Dand, N., Jalali-Najafabadi, F., Bellou, E., Ho, P., Marzo-Ortega, H., Helliwell, P. S., Feletar, M., Ryan, A. W., Kane, D. J., Korendowych, E., Simpson, M. A., Packham, J., McManus, R., Brown, M. A., Smith, C. H., Barker, J. N., McHugh, N., FitzGerald, O., & 2 othersWarren, R. B. & Barton, A., 1 Oct 2017, In: Annals of the rheumatic diseases. 76, 10, p. 1774-1779 6 p.

    Research output: Contribution to journalArticlepeer-review

  35. Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

    Tsoi, L. C., Stuart, P. E., Tian, C., Gudjonsson, J. E., Das, S., Zawistowski, M., Ellinghaus, E., Barker, J. N., Chandran, V., Dand, N., Duffin, K. C., Enerbäck, C., Esko, T., Franke, A., Gladman, D. D., Hoffmann, P., Kingo, K., Kõks, S., Krueger, G. G., Lim, H. W., & 17 othersMetspalu, A., Mrowietz, U., Mucha, S., Rahman, P., Reis, A., Tejasvi, T., Trembath, R., Voorhees, J. J., Weidinger, S., Weichenthal, M., Wen, X., Eriksson, N., Kang, H. M., Hinds, D. A., Nair, R. P., Abecasis, G. R. & Elder, J. T., 24 May 2017, In: Nature Communications. 8, 15382.

    Research output: Contribution to journalArticlepeer-review

  36. Exome-wide association analysis highlights key role of type I IFN signalling pathway in psoriasis pathogenesis

    Dand, N., Sep 2016, In: Journal of Investigative Dermatology. 136, 9, Supplement 2, p. S186 150.

    Research output: Contribution to journalMeeting abstractpeer-review

  37. Genome-wide pathway analysis identifies new genetic pathways associated with psoriasis

    Aterido, A., Julià, A., Ferrándiz, C., Puig, L., Fonseca, E., Fernández-López, E., Dauden, E., Sánchez-Carazo, J. L., López-Estebaranz, J. L., Moreno-Ramírez, D., Vanaclocha, R. F., Herrera, E., de la Cueva, P., Dand, N., Palau, N., Alonso, A., López-Lasanta, M., Tortosa, R., García-Montero, A., Codó, L., & 7 othersGelpí, J. L., Bertranpetit, J., Absher, D., Capon, F., Myers, R. M., Barker, J. N. & Marsal, S., 29 Dec 2015, (E-pub ahead of print) In: Journal of Investigative Dermatology.

    Research output: Contribution to journalArticlepeer-review

  38. BioGranat-IG: a network analysis tool to suggest mechanisms of genetic heterogeneity from exome-sequencing data

    Dand, N., Sprengel, F., Ahlers, V. & Schlitt, T., 15 Mar 2013, In: Bioinformatics (Oxford, England). 29, 6, p. 733-741 9 p.

    Research output: Contribution to journalArticlepeer-review

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