King's College London

Research portal

Professor Nicolas Smith

  1. Decreasing compensatory ability of concentric ventricular hypertrophy in aortic-banded rat hearts

    Lewalle, A., Land, S., Carruth, E., Frank, L. R., Lamata , P., Omens, J. H., McCulloch, A. D., Niederer, S. A. & Smith, N. P. 23 Feb 2018 In : Frontiers in Physiology. 9

    Research output: Contribution to journalArticle

  2. Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding

    Gattoni, S., Treu Røe, Å., Aronsen, J. M., Sjaastad, I., Louch, W. E., Smith, N. P. & Niederer, S. A. 21 May 2017 In : The Journal of physiology.

    Research output: Contribution to journalArticle

  3. Beyond Bernoulli: Improving the Accuracy and Precision of Noninvasive Estimation of Peak Pressure Drops

    Donati, F., Myerson, S., Bissell, M. M., Smith, N. P., Neubauer, S., Monaghan, M. J., Nordsletten, D. A. & Lamata de la Orden, P. 1 Jan 2017 In : Circulation-Cardiovascular Imaging. 10, 1, e005207

    Research output: Contribution to journalArticle

  4. Heterogeneous mechanics of the mouse pulmonary arterial network

    Lee, P., Carlson, B. E., Chesler, N., Olufsen, M. S., Qureshi, M. U., Smith, N. P., Sochi, T. & Beard, D. A. Oct 2016 In : BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 15, 5, p. 1245-61 17 p.

    Research output: Contribution to journalArticle

  5. The calcium-frequency response in the rat ventricular myocyte: an experimental and modelling study

    Gattoni, S., Røe, Å. T., Frisk, M., Louch, W. E., Niederer, S. A. & Smith, N. P. 1 Aug 2016 In : The Journal of physiology. 594, 15, p. 4193-4224 32 p.

    Research output: Contribution to journalArticle

  6. Genome-wide association studies identify genetic loci for low von Willebrand factor levels

    van Loon, J. , Dehghan, A. , Weihong, T. , Trompet, S. , McArdle, W. L. , Asselbergs, F. F. W. , Chen, M-H. , Lopez, L. M. , Huffman, J. E. , Leebeek, F. W. G. , Basu, S. , Stott, D. J. , Rumley, A. , Gansevoort, R. T. , Davies, G. , Wilson, J. J. F. , Witteman, J. C. M. , Cao, X. , de Craen, A. J. M. , Bakker, S. J. L. & 13 others Psaty, B. M., Starr, J. M., Hofman, A., Wouter Jukema, J., Deary, I. J., Hayward, C., van der Harst, P., Lowe, G. D. O., Folsom, A. R., Strachan, D. P., Smith, N., de Maat, M. P. M. & O'Donnell, C. Jul 2016 In : European journal of human genetics : EJHG. 24, 7, p. 1035-40 6 p.

    Research output: Contribution to journalArticle

  7. Accepted/In press

    Evaluation of noise removal algorithms for imaging and reconstruction of vascular networks using micro-CT

    Davidoiu, V., Hadjilucas, L., Teh, I., Smith, N. P., Schneider, J. E. & Lee, C. J. 5 Apr 2016 (Accepted/In press) In : Biomedical Physics & Engineering Express. 2, 4, 045015

    Research output: Contribution to journalArticle

  8. Investigating a novel activation-repolarisation time metric to predict localised Vulnerability to reentry using computational modelling

    Hill, Y. R., Child, N., Hanson, B., Wallman, M., Coronel, R., Plank, G., Rinaldi, C. A., Gill, J., Smith, N. P., Taggart, P. & Bishop, M. J. 2 Mar 2016 In : PL o S One . 11, 3, e0149342

    Research output: Contribution to journalArticle

  9. Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour

    Land, S. , Gurev, V. , Arens, S. , Augustin, C. M. , Baron, L. , Blake, R. , Bradley, C. , Castro, S. , Crozier, W. A. , Favino, M. , Fastl, T. E. , Fritz, T. , Gao, H. , Gizzi, A. , Griffith, B. E. , Hurtado, D. E. , Krause, R. , Luo, X. , Nash, M. P. , Pezzuto, S. & 11 others Plank, G., Rossi, S., Ruprecht, D., Seemann, G., Smith, N. P., Sundnes, J., Rice, J. J., Trayanova, N., Wang, D., Wang, Z. J. & Niederer, S. A. 16 Dec 2015 In : Proceeding of the Royal Society A. 471, p. 1-20 20 p., 20150641

    Research output: Contribution to journalArticle

  10. Non-invasive pressure difference estimation from PC-MRI using the work-energy equation

    Donati, F., Figueroa, C. A., Smith, N. P., Lamata de la Orden, P. & Nordsletten, D. A. 1 Dec 2015 In : MEDICAL IMAGE ANALYSIS. 26, 1, p. 159-172 14 p.

    Research output: Contribution to journalArticle

  11. Factors determining the magnitude of the pre-ejection leftward septal motion in left bundle branch block

    Remme, E. W., Niederer, S., Gjesdal, O., Russell, K., Hyde, E. R., Smith, N. & Smiseth, O. A. 26 Nov 2015 In : EUROPACE. 18, 12, p. 1905-1913

    Research output: Contribution to journalArticle

  12. The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study

    Crozier, A., Blazevic, B., Lamata, P., Plank, G., Ginks, M., Duckett, S., Sohal, M., Shetty, A., Rinaldi, C. A., Razavi, R., Smith, N. P. & Niederer, S. A. 4 Nov 2015 In : Journal of Molecular and Cellular Cardiology.

    Research output: Contribution to journalArticle

  13. Microsphere skimming in the porcine coronary arteries: Implications for flow quantification

    Sinclair, M., Lee, J., Schuster, A., Chiribiri, A., van den Wijngaard, J., van Horssen, P., Siebes, M., Spaan, J. A. E., Nagel, E. & Smith, N. P. Jul 2015 In : Microvascular Research. 100, p. 59-70 12 p.

    Research output: Contribution to journalArticle

  14. Steps towards quantification of the cardiological stress exam

    Chabiniok, R., Sammut, E., Hadjicharalambous, M., Asner, L., Nordsletten, D., Razavi, R. & Smith, N. 21 Jun 2015 Functional Imaging and Modeling of the Heart 2015. Vol. 9126, p. 12-20 (Lecture Notes in Computer Science)

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  15. A technique for continuous measurement of the quality factor of mechanical oscillators

    Smith, N. D. May 2015 In : REVIEW OF SCIENTIFIC INSTRUMENTS. 86, 5, p. 1-6 053907

    Research output: Contribution to journalArticle

  16. Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+,K+-ATPase α2 activity

    Aronsen, J. M., Skogestad, J., Lewalle, A., Louch, W. E., Hougen, K., Stokke, M. K., Swift, F., Niederer, S., Smith, N. P., Sejersted, O. M. & Sjaastad, I. 15 Mar 2015 In : The Journal of Physiology. 593, 6, p. 1509-1521 13 p.

    Research output: Contribution to journalArticle

  17. Manifold learning for cardiac modeling and estimation framework

    Chabiniok, R., Bhatia, K. K., King, A., Rueckert, D. & Smith, N. 2015 LNCS: Proc. of 5th international STACOM workshop. Springer, Vol. 8896, p. 284-294 11 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  18. Accepted/In press

    Multiscale Modelling of Cardiac Perfusion

    Lee, J., Cookson, A., Chabiniok, R., Rivolo, S., Hyde, E., Sinclair, M., Michler, C., Sochi, T. & Smith, N. 2015 (Accepted/In press) Modeling the Heart and the Circulatory System. Springer, p. 51-96

    Research output: Chapter in Book/Report/Conference proceedingChapter

  19. Computational modelling of Takotsubo cardiomyopathy: Effect of spatially varying beta-adrenergic stimulation in the rat left ventricle

    Land, S., Niederer, S., Louch, W. E., Roe, A. T., Aronsen, J. M., Stuckey, D. J., Sikkel, M. B., Tranter, M. H., Lyon, A. R., Harding, S. E. & Smith, N. 15 Nov 2014 In : American Journal of Physiology (Heart and Circulatory Physiology). 307, 10, p. H1487-H1496 10 p.

    Research output: Contribution to journalArticle

  20. Quantitative assessment of magnetic resonance derived myocardial perfusion measurements using advanced techniques: microsphere validation in an explanted pig heart system

    Schuster, A., Zarinabad, N., Ishida, M., Sinclair, M., van den Wijngaard, J. P., Morton, G., Hautvast, G. L., Bigalke, B., van Horssen, P., Smith, N., Spaan, J. A., Siebes, M., Chiribiri, A. & Nagel, E. 14 Oct 2014 In : Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 16, 13 p., 82

    Research output: Contribution to journalArticle

  21. A computational pipeline for quantification of mouse myocardial stiffness parameters

    Nordbø, O., Lamata de la Orden, P., Land, S., Niederer, S., Aronsen, J. M., Louch, W. E., Sjaastad, I., Martens, H., Gjuvsland, A. B., Tøndel, K., Torp, H., Lohezic, M., Schneider, J. E., Remme, E. W., Smith, N., Omholt, S. W. & Vik, J. O. 1 Oct 2014 In : Computers in Biology and Medicine. 53, p. 65-75 11 p.

    Research output: Contribution to journalArticle

  22. Aortic relative pressure components derived from four-dimensional flow cardiovascular magnetic resonance

    Lamata de la Orden, P., Pitcher, A., Krittian, S., Nordsletten, D., Bissell, M. M., Cassar, T., Barker, A. J., Markl, M., Neubauer, S. & Smith, N. P. Oct 2014 In : Magnetic Resonance in Medicine. 72, 4, p. 1162-1169

    Research output: Contribution to journalArticle

  23. Transmural Variation and Anisotropy of Microvascular Flow Conductivity in the Rat Myocardium

    Smith, A. F., Shipley, R. J., Lee, J., Sands, G. B., LeGrice, I. J. & Smith, N. P. Sep 2014 In : Annals of Biomedical Engineering. 42, 9, p. 1966-1977 12 p.

    Research output: Contribution to journalArticle

  24. Automatic selection of optimal Savitzky-Golay filter parameters for Coronary Wave Intensity Analysis

    Rivolo, S., Nagel, E., Smith, N. P. & Lee, J. 1 Aug 2014 Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE. IEEE, p. 5056-5059 4 p. (Engineering in Medicine and Biology Society)

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  25. Pressure mapping from flow imaging: Enhancing computation of the viscous term through velocity reconstruction in near-wall regions

    Donati, F., Nordsletten, D. A., Smith, N. P. & Lamata de la Orden, P. Aug 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2014). IEEE, p. 5097-5100 4 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  26. Understanding the need of ventricular pressure for the estimation of diastolic biomarkers

    Xi, J., Shi, W., Rueckert, D., Razavi, R., Smith, N. P. & Lamata de la Orden, P. Aug 2014 In : BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 13, 4, p. 747-757 11 p.

    Research output: Contribution to journalArticle

  27. Multi-Scale Parameterisation of a Myocardial Perfusion Model Using Whole-Organ Arterial Networks

    Hyde, E. R., Cookson, A. N., Lee, J., Michler, C., Goyal, A., Sochi, T., Chabiniok, R., Sinclair, M., Nordsletten, D. A., Spaan, J., van den Wijngaard, J. P. H. M., Siebes, M. & Smith, N. P. Apr 2014 In : Annals of Biomedical Engineering. 42, 4, p. 797-811 15 p.

    Research output: Contribution to journalArticle

  28. Computational methods to reduce uncertainty in the estimation of cardiac conduction properties from electroanatomical recordings

    Wallman, M., Smith, N. P. & Rodriguez, B. Jan 2014 In : Medical image analysis. 18, 1, p. 228-240 13 p., N/A

    Research output: Contribution to journalArticle

  29. Enhancing coronary Wave Intensity Analysis robustness by high order central finite differences

    Rivolo, S., Asrress, K. N., Chiribiri, A., Sammut, E., Wesolowski, R., Bloch, L. Ø., Grøndal, A. K., Hønge , J., Kim, W. Y., Marber, M., Redwood, S., Nagel, E., Smith, N. & Lee, J. 2014 In : Artery Research. 12 p.

    Research output: Contribution to journalArticle

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