King's College London

Research portal

Professor Pak Sham

  1. Jumping to conclusions, general intelligence, and psychosis liability: Findings from the multi-centre EU-GEI case-control study

    Tripoli, G., Quattrone, D., Ferraro, L., Gayer-Anderson, C., Rodriguez, V., La Cascia, C., La Barbera, D., Sartorio, C., Seminerio, F., Tarricone, I., Berardi, D., Szöke, A., Arango, C., Tortelli, A., Llorca, P. M., De Haan, L., Velthorst, E., Bobes, J., Bernardo, M., Sanjuán, J. & 19 others, Santos, J. L., Arrojo, M., Del-Ben, C. M., Menezes, P. R., Selten, J. P., Jones, P. B., Jongsma, H. E., Kirkbride, J. B., Lasalvia, A., Tosato, S., Richards, A., O'donovan, M., Rutten, B. P. F., Os, J. V., Morgan, C., Sham, P. C., Murray, R. M., Murray, G. K. & Di Forti, M., 1 Jan 2020, (Accepted/In press) In: Psychological Medicine.

    Research output: Contribution to journalArticlepeer-review

  2. LINE1 and Mecp2 methylation of the adult striatum and prefrontal cortex exposed to prenatal immune activation

    Basil, P., Li, Q., Sham, P. C. & McAlonan, G. M., 1 Aug 2019, In: Data in Brief. 25, 104003.

    Research output: Contribution to journalArticlepeer-review

  3. The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study

    EU-GEI WP2 Group, Di Forti, M., Quattrone, D., Freeman, T. P., Tripoli, G., Gayer-Anderson, C., Quigley, H., Rodriguez, V., Jongsma, H. E., Ferraro, L., La Cascia, C., La Barbera, D., Tarricone, I., Berardi, D., Szöke, A., Arango, C., Tortelli, A., Velthorst, E., Bernardo, M., Del-Ben, C. M. & 31 others, Menezes, P. R., Selten, J. P., Jones, P. B., Kirkbride, J. B., Rutten, B. PF., de Haan, L., Sham, P. C., van Os, J., Lewis, C. M., Lynskey, M., Morgan, C., Murray, R. M., Amoretti, S., Arrojo, M., Baudin, G., Beards, S., Bernardo, M., Bobes, J., Bonetto, C., Cabrera, B., Carracedo, A., Charpeaud, T., Costas, J., Cristofalo, D., Cuadrado, P., Díaz-Caneja, C. M., Ferchiou, A., Franke, N., Frijda, F., Hubbard, K. & Stilo, S. A., 1 May 2019, In: The Lancet Psychiatry. 6, 5, p. 427-436 10 p.

    Research output: Contribution to journalArticlepeer-review

  4. IS THE ERA OF CANDIDATE GENES X CANNABIS USE REALLY DEAD?

    Quattrone, D., Lewis, C., Richards, A., Vassos, E., Gayer-Anderson, C., Ferraro, L., Tripoli, G., Rutten, B., O'Donovan, M., Morgan, C., Van Os, J., Sham, P., Reininghaus, U., Murray, R. & Di Forti, M., 2019, In: European Neuropsychopharmacology. 29, p. 1324-1325

    Research output: Contribution to journalMeeting Abstractpeer-review

  5. POLYGENIC RISK SCORE FOR PARKINSON DISORDER IS NEGATIVELY ASSOCIATED WITH PSYCHOTIC DISORDERS

    Quattrone, D., Lewis, C., Richards, A., O'Donovan, M., Sham, P., Tripoli, G., Morgan, C., Reininghaus, U., Murray, R. & Di Forti, M., 2019, In: European Neuropsychopharmacology. 29, p. 1252-1253

    Research output: Contribution to journalMeeting Abstractpeer-review

  6. MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes

    Fung, G., Cheung, C., Chen, E., Lam, C., Chiu, C., Law, C-W., Leung, M-K., Deng, M., Cheung, V., Qi, L., Nailin, Y., Tai, K-S., Yip, L., Suckling, J., Sham, P., McAlonan, G. & Chua, S-E., Jul 2014, In: Neuropsychobiology. 69, 4, p. 243-248 6 p.

    Research output: Contribution to journalArticlepeer-review

  7. Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain

    Basil, P., Li, Q., Dempster, E. L., Mill, J., Sham, P-C., Wong, C. C. Y. & McAlonan, G. M., 2014, In: Translational psychiatry. 4, p. 1-7 7 p., e434.

    Research output: Contribution to journalArticlepeer-review

  8. HLA-DP and IL28B polymorphisms: influence of host genome on hepatitis B surface antigen seroclearance in chronic hepatitis B

    Seto, W-K., Wong, D. K-H., Kopaniszen, M., Proitsi, P., Sham, P-C., Hung, I. F-N., Fung, J., Lai, C-L. & Yuen, M-F., Jun 2013, In: Clinical Infectious Diseases. 56, 12, p. 1695-1703 9 p.

    Research output: Contribution to journalArticlepeer-review

  9. RET and NRG1 interplay in Hirschsprung disease

    Gui, H., Tang, W-K., So, M-T., Proitsi, P., Sham, P. C., Tam, P. K., Ngan, E. S-W., Cherny, S. S. & Garcia-Barceló, M-M., 1 Feb 2013, In: Human Genetics. 132, 5, p. 591-600 10 p.

    Research output: Contribution to journalArticlepeer-review

  10. Common Polymorphisms in the SERPINI2 Gene Are Associated with Refractive Error in the 1958 British Birth Cohort

    Hysi, P. G., Simpson, C. L., Fok, Y. K. Y., Gerrelli, D., Webster, A. R., Bhattacharya, S. S., Hammond, C. J., Sham, P. C. & Rahi, J. S., Jan 2012, In: Investigative Ophthalmology & Visual Science. 53, 1, p. 440 - 447 8 p.

    Research output: Contribution to journalArticlepeer-review

  11. A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25

    Hysi, P. G., Young, T. L., Mackey, D. A., Andrew, T., Fernández-Medarde, A., Solouki, A. M., Hewitt, A. W., Macgregor, S., Vingerling, J. R., Li, Y-J., Ikram, M. K., Fai, L. Y., Sham, P. C., Manyes, L., Porteros, A., Cabrita Lopes, M., Carbonaro, F., Fahy, S. J., Martin, N. G., van Duijn, C. M. & 5 others, Spector, T. D., Rahi, J. S., Santos, E., Klaver, C. C. W. & Hammond, C. J., Oct 2010, In: Nature Genetics. 42, 10, p. 902-905 4 p.

    Research output: Contribution to journalArticlepeer-review

  12. Commingling Analyses of Central Corneal Thickness and Adjusted Intraocular Pressure in an Older Australian Population

    Rahman, M. L., Bunce, C., Healey, P. R., Mitchell, P., Sham, P. C., McGuffin, P. & Viswanathan, A. C., May 2010, In: Investigative Ophthalmology & Visual Science. 51, 5, p. 2512 - 2518 7 p.

    Research output: Contribution to journalArticlepeer-review

  13. Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study

    MacCabe, J. H., Lambe, M. P., Cnattingius, S., Sham, P. C., David, A. S., Reichenberg, A., Murray, R. M. & Hultman, C. M., Feb 2010, In: British Journal of Psychiatry. 196, 2, p. 109 - 115 7 p.

    Research output: Contribution to journalArticlepeer-review

  14. Prenatal immune challenge is an environmental risk factor for brain and behavior change relevant to schizophrenia: evidence from MRI in a mouse model

    Li, Q., Cheung, C., Wei, R., Hui, E. S., Feldon, J., Meyer, U., Chung, S., Chua, S. E., Sham, P. C., Wu, E. X. & McAlonan, G., 24 Jul 2009, In: PL o S One . 4, 7, p. e6354 e6354.

    Research output: Contribution to journalArticlepeer-review

  15. Scholastic achievement at age 16 and risk of schizophrenia and other psychoses: a national cohort study

    MacCabe, J., Lambe, M. P., Cnattingius, S., Torrång, A., Sham, P. C., David, A. S., Murray, R. M. & Hultman, C. M., Aug 2008, In: Psychological Medicine. 38, 8, p. 1133-1140 8 p.

    Research output: Contribution to journalArticlepeer-review

  16. Abnormal P300 in people with high risk of developing psychosis

    Bramon, E., Shaikh, M., Broome, M., Lappin, J., Bergé, D., Day, F., Woolley, J., Tabraham, P., Madre, M., Johns, L., Howes, O., Valmaggia, L., Pérez, V., Sham, P., Murray, R. M. & McGuire, P., Jun 2008, In: NeuroImage. 41, 2, p. 553-560 8 p.

    Research output: Contribution to journalArticlepeer-review

  17. Positional Pathway Screen of wnt Signaling Genes in Schizophrenia: Association with DKK4

    Proitsi, P., Li, T., Hamilton, G., Di Forti, M., Collier, D., Killick, R., Chen, R., Sham, P., Murray, R., Powell, J. & Lovestone, S., 1 Jan 2008, In: Biological psychiatry. 63, 1, p. 13 - 16 4 p.

    Research output: Contribution to journalArticlepeer-review

  18. The Roles of PAX6 and SOX2 in Myopia: lessons from the 1958 British Birth Cohort

    Simpson, C. L., Hysi, P., Bhattacharya, S. S., Hammond, C. J., Webster, A., Peckham, C. S., Sham, P. C. & Rahi, J. S., Oct 2007, In: Investigative Ophthalmology & Visual Science. 48, 10, p. 4421-4425 5 p.

    Research output: Contribution to journalArticlepeer-review

  19. Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality

    Fogh, I., Rijsdijk, F., Andersen, P. M., Sham, P. C., Knight, J., Neale, B., Kenna-Yasek, D., Silani, V., Brown, R. H., Powell, J. F. & Al-Chalabi, A., Aug 2007, In: NEUROGENETICS. 8, 3, p. 235 - 236 2 p.

    Research output: Contribution to journalLetterpeer-review

  20. Genetic overlap between bipolar illness and event-related potentials

    Hall, M. H., Rijsdijk, F., Kalidindi, S., Schulze, K., Kravariti, E., Kane, F., Sham, P., Bramon, E. & Murray, R. M., May 2007, In: Psychological Medicine. 37, 5, p. 667 - 678 12 p.

    Research output: Contribution to journalArticlepeer-review

  21. Immediate and sustained psychological impact of an emergin disease outbreak on health care workers

    McAlonan, G., Lee, A. M., Cheung, V., Cheung, C., Tsang, K. W. T., Sham, P., Chua, S. E. & Wong, J. G. W. S., Apr 2007, In: Canadian Journal of Psychiatry. 52, 4, p. 241-247 7 p.

    Research output: Contribution to journalArticlepeer-review

  22. Stress and psychological distress among SARS survivors 1 year after the outbreak

    Lee, A. M., Wong, J. G. W. S., McAlonan, G. M., Cheung, V., Cheung, C., Sham, P. C., Chu, C-M., Wong, P-C., Tsang, K. W. T. & Chua, S. E., Apr 2007, In: Canadian Journal of Psychiatry. 52, 4, p. 233-240 8 p.

    Research output: Contribution to journalArticlepeer-review

  23. Reaction time of the Continuous Performance Test is an endophenotypic marker for schizophrenia: A study of first-episode neuroleptic-naive schizophrenia, their non-psychotic first-degree relatives and healthy population controls

    Wang, Q., Chan, R., Sun, J. H., Yao, J., Deng, W., Sun, X. L., Liu, X. H., Sham, P. C., Ma, X. H., Meng, H. Q., Murray, R. M., Collier, D. A. & Li, T., Jan 2007, In: Schizophrenia Research. 89, 1-3, p. 293 - 298 6 p.

    Research output: Contribution to journalArticlepeer-review

  24. Proteome-based plasma biomarkers for Alzheimer's disease

    Hye, A., Lynham, S., Thambisetty, M., Causevic, M., Campbell, J., Byers, H. L., Hooper, C., Rijsdijk, F., Tabrizi, S. J., Banner, S., Shaw, C. E., Foy, C., Poppe, M., Archer, N., Hamilton, G., Powell, J., Brown, R. G., Sham, P., Ward, M. & Lovestone, S., Nov 2006, In: Brain. 129, 11, p. 3042 - 3050 9 p.

    Research output: Contribution to journalArticlepeer-review

  25. The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

    Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., Aneey, R., Franke, R., Gill, M., Ebstein, R., Buitelaar, J., Sham, P., Campbell, D., Knight, J., Andreou, P., Altink, M., Arnold, R., Boer, F., Buschgens, C., Butler, L. & 42 others, Christiansen, H., Feldman, L., Fleischman, K., Fliers, E., Howe-Forbes, R., Goldfarb, A., Heise, A., Gabriëls, I., Korn-Lubetzki, I., Marco, R., Medad, S., Minderaa, R., Mulas, F., Müller, U., Mulligan, A., Rabin, K., Rommelse, N., Sethna, V., Sorohan, J., Uebel, H., Psychogiou, L., Weeks, A., Barrett, R., Craig, I., Banaschewski, T., Sonuga-Barke, E., Eisenberg, J., Kuntsi, J., Manor, I., McGuffin, P., Miranda, A., Oades, R. D., Plomin, R., Roeyers, H., Rothenberger, A., Sergeant, J., Steinhausen, H-C., Taylor, E., Thompson, M., Faraone, S. V., Asherson, P. & Johansson, L., 9 Oct 2006, In: Molecular Psychiatry. 11, 10, p. 934 - 953 20 p.

    Research output: Contribution to journalArticlepeer-review

  26. Design and analysis of association studies using pooled DNA from large twin samples

    Knight, J. & Sham, P., Sep 2006, In: Behavior Genetics. 36, 5, p. 665 - 677 13 p.

    Research output: Contribution to journalArticlepeer-review

  27. Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia

    Kravariti, E., Toulopoulou, T., Mapua-Filbey, F., Schulze, K., Walshe, M., Sham, P., Murray, R. M. & McDonald, C., Feb 2006, In: British Journal of Psychiatry. 188, FEB., p. 186 - 187 2 p.

    Research output: Contribution to journalArticlepeer-review

  28. Whole genome linkage scan of recurrent depressive disorder from the depression network study

    McGuffin, P., Knight, J., Breen, G., Brewster, S., Boyd, P. R., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Perry, J., Preisig, M., Reich, T., Rice, J., Rietschel, M., Jones, L., Sham, P. & Farmer, A. E., 15 Nov 2005, In: Human Molecular Genetics. 14, 22, p. 3337-3345 9 p.

    Research output: Contribution to journalArticlepeer-review

  29. Identifying potential risk haplotypes for schizophrenia at the DTNBP1 locus in Han Chinese and Scottish populations

    Li, T., Zhang, F., Liu, X., Sun, X., Sham, P. C., Crombie, C., Ma, X., Wang, Q., Meng, H., Deng, W., Yates, P., Hu, X., Walker, N., Murray, R. M., St Clair, D. & Collier, D. A., Nov 2005, In: Molecular Psychiatry. 10, 11, p. 1037 - 1044 8 p.

    Research output: Contribution to journalArticlepeer-review

  30. Is the P300 wave an endophenotype for schizophrenia? A meta-analysis and a family study

    Bramon, E., McDonald, C., Croft, R. J., Landau, S., Filbey, F., Gruzelier, J. H., Sham, P. C., Frangou, S. & Murray, R. M., 1 Oct 2005, In: NeuroImage. 27, 4, p. 960 - 968 9 p.

    Research output: Contribution to journalArticlepeer-review

  31. Brain MRI abnormalities in schizophrenia: same genes or same environment?

    Rijsdijk, F. V., van Haren, N. E. M., Picchioni, M. M., McDonald, C., Toulopoulou, T., Hulshoff Pol, H. E., Kahn, R. S., Murray, R. & Sham, P. C., Oct 2005, In: Psychological Medicine. 35, 10, p. 1399 - 1409 11 p.

    Research output: Contribution to journalArticlepeer-review

  32. Dermatoglyphics and schizophrenia: A meta-analysis and investigation of the impact of obstetric complications upon a-b ridge count

    Bramon, E., Walshe, M., McDonald, C., Martin, B., Toulopoulou, T., Wickham, H., van Os, J., Fearon, P., Sham, P., Fananas, L. & Murray, R. M., 15 Jun 2005, In: Schizophrenia Research. 75, 2-3, p. 399 - 404 6 p.

    Research output: Contribution to journalArticlepeer-review

  33. SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children

    Butcher, L. M., Meaburn, E., Knight, J., Sham, P. C., Schalkwyk, L. C., Craig, I. W. & Plomin, R., 15 May 2005, In: Human Molecular Genetics. 14, 10, p. 1315 - 1325 11 p.

    Research output: Contribution to journalArticlepeer-review

  34. Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: Computational morphometry study

    McDonald, C., Bullmore, E., Sham, P., Chitnis, X., Suckling, J., MacCabe, J., Walshe, M. & Murray, R. M., May 2005, In: British Journal of Psychiatry. 186, 5, p. 369 - 377 9 p.

    Research output: Contribution to journalArticlepeer-review

  35. Association between BDNF val66 met genotype and episodic memory

    Dempster, E., Toulopoulou, T., McDonald, C., Bramon, E., Walshe, M., Filbey, F., Wickham, H., Sham, P. C., Murray, R. M. & Collier, D. A., 5 Apr 2005, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 134, 1, p. 73 - 75 3 p.

    Research output: Contribution to journalArticlepeer-review

  36. Association analysis of mild mental impairment using DNA pooling to screen 432 brain-expressed single-nucleotide polymorphisms

    Butcher, L. M., Meaburn, E., Dale, P. S., Sham, P., Schalkwyk, L. C., Craig, I. W. & Plomin, R., Apr 2005, In: Molecular Psychiatry. 10, 4, p. 384 - 392 9 p.

    Research output: Contribution to journalArticlepeer-review

  37. Parental phenotypes in family-based association analysis

    Purcell, S., Sham, P. & Daly, M. J., Feb 2005, In: American Journal of Human Genetics. 76, 2, p. 249 - 259 11 p.

    Research output: Contribution to journalArticlepeer-review

  38. Relapse prevention in patients with bipolar disorder: Cognitive therapy outcome after 2 years

    Lam, D. H., Hayward, P., Watkins, E. R., Wright, K. & Sham, P., Feb 2005, In: The American Journal of Psychiatry. 162, 2, p. 324 - 329 6 p.

    Research output: Contribution to journalArticlepeer-review

  39. Obstetric complications in patients with schizophrenia and their unaffected siblings

    Walshe, M., McDonald, C., Taylor, M., Zhao, J., Sham, P., Grech, A., Schulze, K., Bramon, E. & Murray, R. M., Jan 2005, In: European Psychiatry. 20, 1, p. 28 - 34 7 p.

    Research output: Contribution to journalArticlepeer-review

  40. Sense of hyper-positive self and response to cognitive therapy in bipolar disorder

    Lam, D., Wright, K. & Sham, P., Jan 2005, In: Psychological Medicine. 35, 1, p. 69 - 77 9 p.

    Research output: Contribution to journalArticlepeer-review

  41. A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays

    Simpson, C. L., Knight, J., Butcher, L. M., Hansen, V. K., Meaburn, E., Schalkwyk, L. C., Craig, I. W., Powell, J. F., Sham, P. C. & Al-Chalabi, A., 2005, In: Nucleic Acids Research. 33, 3, p. e25 5 p.

    Research output: Contribution to journalArticlepeer-review

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