King's College London

Research portal

Dr Paola Di Meglio

  1. Global reporting of cases of COVID-19 in psoriasis and atopic dermatitis: an opportunity to inform care during a pandemic

    The Secure-AD, PsoPROTECT study groups, 1 Aug 2020, In : British Journal of Dermatology. 183, 2, p. 404-406 3 p.

    Research output: Contribution to journalLetter

  2. T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis

    Farrera, C., Melchiotti, R., Petrov, N., Wei Weng Teng, K., Wong, M. T., Loh, C. Y., Villanova, F., Tosi, I., Chen, J., Grys, K., Sreeneebus, H., Chapman, A., Perera, G. K., Heck, S., Gracio, F., de Rinaldis, E., Barker, J. N., Smith, C. H., Nestle, F. O., Newell, E. W. & 1 others, Di Meglio, P., 1 Mar 2020, In : Journal of Allergy and Clinical Immunology. 145, 3, p. 1021-1025.e15

    Research output: Contribution to journalArticle

  3. Aldara-induced dermatitis is associated with development of liver fibrosis in mice

    Maybury, C. M., Di Meglio, P. & Smith, C. H., Jul 2018, In : British Journal of Dermatology. 179, 1, p. 9-10 2 p.

    Research output: Contribution to journalComment/debate

  4. AP1S3 mutations cause skin autoinflammation by disrupting keratinocyte autophagy and up-regulating IL-36 production

    Mahil, S. K., Twelves, S., Farkas, K., Setta-Kaffetzi, N., Burden, A. D., Gach, J. E., Irvine, A. D., Képíró, L., Mockenhaupt, M., Oon, H. H., Pinner, J., Ranki, A., Seyger, M. MB., Soler-Palacin, P., Storan, E. R., Tan, E. S., Valeyrie-Allanore, L., Young, H. S., Trembath, R. C., Choon, S-E. & 6 others, Szell, M., Bata-Csorgo, Z., Smith, C. H., Di Meglio, P., Barker, J. N. & Capon, F., Nov 2016, In : Journal of Investigative Dermatology. 136, 11, p. 2251–2259

    Research output: Contribution to journalArticle

  5. Targeting CD8+ T cells prevents psoriasis development

    Di Meglio, P., Villanova, F., Navarini, A. A., Mylonas, A., Tosi, I., Nestle, F. O. & Conrad, C., Jul 2016, In : Journal of Allergy and Clinical Immunology. 138, 1, p. 274-276.e6

    Research output: Contribution to journalLetter

  6. Psoriasis, Cutaneous Lupus Erithematosus and Immunobiology of the Skin

    Di Meglio, P., 2016, Encyclopedia of Immunobiology.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  7. The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis

    Roederer, M., Quaye, L., Mangino, M., Beddall, M. H., Mahnke, Y., Chattopadhyay, P., Tosi, I., Napolitano, L., Terranova Barberio, M., Menni, C., Villanova, F., Di Meglio, P., Spector, T. D. & Nestle, F. O., 9 Apr 2015, In : Cell. 161, 2, 17 p.

    Research output: Contribution to journalArticle

  8. Targeted Therapies and Biomarkers for Personalized Treatment of Psoriasis

    Di Meglio, P., 2015, Personalized Treatment Options in Dermatology.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  9. IL-22 fate reporter reveals origin and control of IL-22 production in homeostasis and infection

    Ahlfors, H., Morrison, P. J., Duarte, J. H., Li, Y., Biro, J., Tolaini, M., Di Meglio, P., Potocnik, A. J. & Stockinger, B., 1 Nov 2014, In : Journal of Immunology. 193, 9, p. 4602-4613

    Research output: Contribution to journalArticle

  10. Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions

    Di Meglio, P., Duarte, J. H., Ahlfors, H., Owens, N. D. L., Li, Y., Villanova, F., Tosi, I., Hirota, K., Nestle, F. O., Mrowietz, U., Gilchrist, M. J. & Stockinger, B., 19 Jun 2014, In : Immunity. 40, 6, p. 989-1001 13 p.

    Research output: Contribution to journalArticle

  11. Characterization of Innate Lymphoid Cells in Human Skin and Blood Demonstrates Increase of NKp44+ILC3 in Psoriasis

    Villanova, F., Flutter, B., Tosi, I., Grys, K., Sreeneebus, H., Perera, G., Chapman, A., Smith, C., Di Meglio, P. & Nestle, F., Apr 2014, In : Journal of Investigative Dermatology. 134, 4, p. 984-991 8 p.

    Research output: Contribution to journalArticle

  12. Psoriasis

    Di Meglio, P., 2014, In : Cold Spring Harbor perspectives in medicine.

    Research output: Contribution to journalReview article

  13. The aryl hydrocarbon receptor: multitasking in the immune system.

    Di Meglio, P., 2014, In : Annual Review of Immunology.

    Research output: Contribution to journalReview article

  14. Gene expression changes with age in skin, adipose tissue, blood and brain

    Glass, D., Vinuela, A., Davies, M. N., Ramasamy, A., Parts, L., Knowles, D., Brown, A. A., Hedman, A. K., Small, K. S., Buil, A., Grundberg, E., Nica, A. C., Di Meglio, P., Nestle, F. O., Ryten, M., Durbin, R., McCarthy, M. I., Deloukas, P., Dermitzakis, E. T., Weale, M. E. & 4 others, Bataille, V., Spector, T. D., UK Brain Expression Consortium & MuTHER Consortium, 26 Jul 2013, In : GENOME BIOLOGY. 14, 7, p. N/A 12 p., R75.

    Research output: Contribution to journalArticle

  15. Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery

    Villanova, F., Di Meglio, P., Inokuma, M., Aghaeepour, N., Perucha, E., Mollon, J., Nomura, L., Hernandez Fuentes, M., Cope, A., Prevost, A. T., Heck, S., Maino, V., Lord, G., Brinkman, R. R. & Nestle, F. O., 3 Jul 2013, In : PLoS ONE. 8, 7, 8 p., e65485.

    Research output: Contribution to journalArticle

  16. Differential Influences of the Aryl Hydrocarbon Receptor on Th17 Mediated Responses in vitro and in vivo

    Duarte, J. H., Di Meglio, P., Hirota, K., Ahlfors, H. & Stockinger, B., 2013, In : PLOS One. 8, 11, e79819.

    Research output: Contribution to journalArticle

  17. Mapping cis- and trans-regulatory effects across multiple tissues in twins

    Grundberg, E., Small, K. S., Hedman, A. K., Nica, A. C., Buil, A., Keildson, S., Bell, J. T., Yang, T-P., Meduri, E., Barrett, A., Nisbett, J., Sekowska, M., Wilk, A., Shin, S-Y., Glass, D., Travers, M., Min, J. L., Ring, S., Ho, K., Thorleifsson, G. & 31 others, Kong, A., Thorsteindottir, U., Ainali, C., Dimas, A. S., Hassanali, N., Ingle, C., Knowles, D., Krestyaninova, M., Lowe, C. E., Di Meglio, P., Montgomery, S. B., Parts, L., Potter, S., Surdulescu, G., Tsaprouni, L., Tsoka, S., Bataille, V., Durbin, R., Nestle, F. O., O'Rahilly, S., Soranzo, N., Lindgren, C. M., Zondervan, K. T., Ahmadi, K. R., Schadt, E. E., Stefansson, K., Smith, G. D., McCarthy, M. I., Deloukas, P., Spector, T. D. & Multiple Tissue Human Expression R, Oct 2012, In : Nature Genetics. 44, 10, p. 1084-1089 8 p.

    Research output: Contribution to journalArticle

  18. Allele-Specific Cytokine Responses at the HLA-C Locus: Implications for Psoriasis

    Hundhausen, C., Bertoni, A., Mak, R. K., Botti, E., Di Meglio, P., Clop, A., Laggner, U., Chimenti, S., Hayday, A. C., Barker, J. N., Trembath, R. C., Capon, F. & Nestle, F. O., Mar 2012, In : Journal of Investigative Dermatology. 132, 3, p. 635 - 641 7 p.

    Research output: Contribution to journalArticle

  19. Biomarker discovery in psoriasis using a multiparameter flow cytometry platform

    Villanova, F., Di Meglio, P., Inokuma, M., Heck, S., Perucha, E., Brinkman, R., Fuentes, M. H., Lord, G., Maino, S. V. & Nestle, F. O., 2012, In : British Journal of Dermatology. 166, 4, p. e37 - e37

    Research output: Contribution to journalMeeting abstract

  20. The Multitasking Organ: Recent Insights into Skin Immune Function

    Di Meglio, P., Perera, G. K. & Nestle, F. O., 23 Dec 2011, In : Immunity. 35, 6, p. 857 - 869 13 p.

    Research output: Contribution to journalLiterature review

  21. Immunological biomarker discovery in psoriasis using an advanced flow cytometry platform

    Villanova, F., Di Meglio, P., Inokuma, M., Heck, S., Perucha, E., Fuentes, M. H., Maino, S., Lord, G. & Nestle, F. O., Dec 2011, In : British Journal of Dermatology. 165, 6, p. E39-E40 2 p.

    Research output: Contribution to journalMeeting abstract

  22. Harnessing dendritic cells in inflammatory skin diseases

    Chu, C-C., Di Meglio, P. & Nestle, F. O., Feb 2011, In : Seminars in Immunology. 23, 1, p. 28 - 41 14 p.

    Research output: Contribution to journalLiterature review

  23. The architecture of gene regulatory variation across multiple human tissues: the MuTHER study

    Nica, A. C., Parts, L., Glass, D., Nisbet, J., Barrett, A., Sekowska, M., Travers, M., Potter, S., Grundberg, E., Small, K., Hedman, A. K., Bataille, V., Bell, J. T., Surdulescu, G., Dimas, A. S., Ingle, C., Nestle, F. O., di Meglio, P., Min, J. L., Wilk, A. & 15 others, Hammond, C. J., Hassanali, N., Yang, T-P., Montgomery, S. B., O'Rahilly, S., Lindgren, C. M., Zondervan, K. T., Soranzo, N., Barroso, I., Durbin, R., Ahmadi, K., Deloukas, P., McCarthy, M. I., Dermitzakis, E. T. & Spector, T. D., Feb 2011, In : PL o S Genetics. 7, 2, e1002003.

    Research output: Contribution to journalArticle

  24. A multiparameter flow cytometry platform for immunological biomarker discovery in psoriasis

    Villanova, F., Di Meglio, P., Inokuma, M., Heck, S., Perucha, E., Fuentes, M. H., Maino, S., Lord, G. & Nestle, F. O., 2011, In : British Journal of Dermatology. 164, 4, p. 919 - 919 1 p.

    Research output: Contribution to journalMeeting abstract

  25. Biomarkers of skin ageing using genome wide transcriptomics

    Glass, D., Parts, L., Knowles, D., Nica, A. C., Nisbet, J., Barrett, A., Sekowska, M., Travers, M., Potter, S., Grundberg, E., Small, K., Hedman, A. S. A., Bell, J. T., Surdulescu, G., Nestle, F. O., di Meglio, P., Durbin, R., Ahmadi, K., Winn, J., Bataille, V. & 5 others, Deloukas, P., McCarthy, M. I., Spector, T. D., Dermitzakis, E. T. & For, M., 2011, In : Journal of Investigative Dermatology. 131, p. S66 - S66

    Research output: Contribution to journalMeeting abstract

  26. Biomarkers of skin ageing using genome wide transcriptomics

    Glass, D., Parts, L., Knowles, D., Nica, A. C., Nisbet, J., Barrett, A., Sekowska, M., Travers, M., Potter, S., Grundberg, E., Small, K., Hedman, A., Bell, J. T., Surdulescu, G., Dimas, A. S., Ingle, C., Nestle, F. O., di Meglio, P., Min, J. L., Wilk, A. & 16 others, Hammond, C. J., Hassanali, N., Yang, T. -P., Montgomery, S. B., Lindgren, C. M., Zondervan, K. T., Soranzo, N., Barroso, I., Durbin, R., Ahmadi, K., Winn, J., Bataille, V., Deloukas, P., McCarthy, M. I., Spector, T. D. & Dermitzakis, E. T., 2011, In : British Journal of Dermatology. 164, 4, p. 931 - 931 1 p.

    Research output: Contribution to journalMeeting abstract

  27. Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis

    Tonel, G., Conrad, C., Laggner, U., Di Meglio, P., Grys, K., McClanahan, T. K., Blumenschein, W. M., Qin, J-Z., Xin, H., Oldham, E., Kastelein, R., Nickoloff, B. J. & Nestle, F. O., 15 Nov 2010, In : Journal of Immunology. 185, 10, p. 5688 - 5691 4 p.

    Research output: Contribution to journalArticle

  28. A model for harmonizing flow cytometry in clinical trials

    Maecker, H. T., McCoy, J. P., Amos, M., Elliott, J., Gaigalas, A., Wang, L., Aranda, R., Banchereau, J., Boshoff, C., Braun, J., Korin, Y., Reed, E., Cho, J., Hafler, D., Davis, M., Fathman, C. G., Robinson, W., Denny, T., Weinhold, K., Desai, B. & 25 others, Diamond, B., Gregersen, P., Di Meglio, P., DiMeglio, P., Nestle, F. O., Nestle, F., Peakman, M., Villanova, F., Villnova, F., Ferbas, J., Field, E., Kantor, A., Kawabata, T., Komocsar, W., Lotze, M., Nepom, J., Ochs, H., O'Lone, R., Phippard, D., Plevy, S., Rich, S., Roederer, M., Rotrosen, D., Yeh, J-H. & FOCIS Human Immunophenotyping Consortium, Nov 2010, In : Nature Immunology. 11, 11, p. 975-8 4 p.

    Research output: Contribution to journalArticle

  29. Discovery and validation of immunological biomarkers using an advanced flow cytometry platform

    Villanova, F., Di Meglio, P., Inokuma, M., Maino, S. & Nestle, F. O., 2010, In : British Journal of Dermatology. 162, 4, p. 936 - 936 1 p.

    Research output: Contribution to journalMeeting abstract

  30. Skin immune sentinels in health and disease

    Nestle, F. O., Di Meglio, P., Qin, J-Z. & Nickoloff, B. J., Oct 2009, In : NATURE REVIEWS IMMUNOLOGY. 9, 10, p. 679 - 691 13 p.

    Research output: Contribution to journalLiterature review

  31. The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis

    Di Cesare, A., Di Meglio, P. & Nestle, F. O., Jun 2009, In : Journal of Investigative Dermatology. 129, 6, p. 1339 - 1350 12 p.

    Research output: Contribution to journalLiterature review

  32. A Gene-to-Function Analysis of IL-23R Arg381Gln Polymorphism Reveals Impaired IL-17A Production in Th17 Cells

    Di Meglio, P., Di Cesare, A., Laggner, U., Chu, C-C., Peris, K. & Nestle, F., 2009, In : CLINICAL IMMUNOLOGY. 131, p. S97 - S97

    Research output: Contribution to journalMeeting abstract

  33. Investigating the Role of Skin Homing V gamma 9V delta 2 T Cells as Novel Pathogenic Cells in Psoriasis

    Laggner, U., Di Meglio, P., Hundhausen, C., Perera, G., Botti, E., Hayday, A. & Nestle, F., 2009, In : CLINICAL IMMUNOLOGY. 131, p. S25 - S26

    Research output: Contribution to journalMeeting abstract

  34. The skin-homing V gamma 9V delta 2 T cell - a potential role in psoriasis?

    Laggner, U., Di Meglio, P., Hundhausen, C., Perera, G., Botti, E., Mak, R., Hayday, A. & Nestle, F. O., 2009, In : British Journal of Dermatology. 160, 4, p. 910 - 910 1 p.

    Research output: Contribution to journalMeeting abstract

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