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  UKRI CoA: The Impact Of Early Adversity On Trajectories Of Brain Maturation And Mental Health In Young Adolescents

  Dazzan, P. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/01/2021 → 30/09/2021

  Project: Research

• Normative brain charting for predicting and stratifying psychosis

  Dazzan, P. (Primary Investigator) & McGuire, P. (Co-Investigator)

  Wellcome Trust

  1/10/2019 → 1/01/2023

  Project: Research

• SHAPER: Scaling-up Health-Arts Programmes: Implementation and Effectiveness Research

  Pariante, C. (Primary Investigator), Dazzan, P. (Co-Investigator), Ray Chaudhuri, K. (Co-Investigator), Bakolis, I. (Co-Investigator), Healey, A. (Co-Investigator), Davis, R. (Co-Investigator), Soukup , T. (Co-Investigator) & Sevdalis, N. (Co-Investigator)

  Wellcome Trust

  1/10/2019 → 31/12/2023

  Project: Research

• BIPP: Brain, Immunity and Psychopathology following very Preterm birth

  Nosarti, C. (Primary Investigator), Edwards, D. (Co-Investigator), Hajnal, J. (Co-Investigator), Counsell, S. (Co-Investigator), Simonoff, E. (Co-Investigator), Pariante, C. (Co-Investigator), Dazzan, P. (Co-Investigator) & Pickles, A. (Co-Investigator)

  MRC Medical Research Council

  1/09/2019 → 31/08/2023

  Project: Research

  • Mental Health 100%
  • Temperament 77%
  • Anxiety 72%
  • Stressors 66%
  • Internalizing 66%

• The Impact of Early Adversity on Trajectories of Brain Maturation and Mental Health in Young Adolescents

  Dazzan, P. (Primary Investigator), Morgan, C. (Co-Investigator), Schumann, G. (Co-Investigator), Pariante, C. (Co-Investigator), Nosarti, C. (Co-Investigator), Mehta, M. (Co-Investigator) & Harding, S. (Co-Investigator)

  MRC Medical Research Council

  1/10/2018 → 30/09/2022

  Project: Research

• Understanding the role of gender, inflammation and sex hormones in the prevention and treatment of affective disorders

  Pariante, C. (Primary Investigator), Dazzan, P. (Co-Investigator) & Mondelli, V. (Co-Investigator)

  Psychiatry Research Trust

  1/10/2018 → 30/09/2021

  Project: Research

• Strengthening the primary care system for adolescent indigenous health in Brazil: Integrating community health workers into the school setting

  Harding, S. (Primary Investigator), Dazzan, P. (Co-Investigator), Wolfe, I. (Co-Investigator) & O'Keeffe, M. (Co-Investigator)

  MRC Medical Research Council

  1/04/2018 → 30/09/2021

  Project: Research

• Neurobiological Determinants of Negative Symptoms of Schizophrenia

  Demjaha, A. (Primary Investigator), Dazzan, P. (Co-Investigator) & McGuire, P. (Co-Investigator)

  15/01/2017 → 14/01/2019

  Project: Research

• Identifying gene expression and neuroimaging markers for postpartum psychosis

  Fuste Boadella, M. (Primary Investigator), Dazzan, P. (Co-Investigator), Mondelli, V. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/01/2017 → 31/12/2018

  Project: Research

• Bio-REACH: The biology of Risk, Resilience, Ethnicity and AdolesCent Mental Health

  Dazzan, P. (Primary Investigator), Harding, S. (Co-Investigator), McGuire, P. (Co-Investigator), Mehta, M. (Co-Investigator), Mondelli, V. (Co-Investigator), Montana, G. (Co-Investigator), Morgan, C. (Co-Investigator), Nosarti, C. (Co-Investigator) & Pariante, C. (Co-Investigator)

  15/10/2016 → 15/10/2020

  Project: Research

• Identifying gene expression and neuroimaging markers for postpartum psychosis

  Fuste Boadella, M. (Primary Investigator), Dazzan, P. (Co-Investigator), Mondelli, V. (Co-Investigator) & Pariante, C. (Co-Investigator)

  Academy of Medical Sciences

  1/08/2016 → 4/08/2017

  Project: Research

• REBECCA

  Dazzan, P. (Primary Investigator)

  1/01/2016 → 31/12/2020

  Project: Research

• Neurobiology of psychotic negative symptoms and of their response to treatmentDefining the role of IL-17

  Demjaha, A. (Primary Investigator), Dazzan, P. (Co-Investigator) & McGuire, P. (Co-Investigator)

  1/12/2015 → 30/11/2019

  Project: Research

• Randomised, placebo-controlled trial of Omega-3 fatty acids in pregnant women at risk of postpartum psychosis

  Dazzan, P. (Primary Investigator), Howard, L. (Co-Investigator), Landau, S. (Co-Investigator), Pariante, C. (Co-Investigator) & Patel, M. (Co-Investigator)

  1/11/2015 → 31/10/2018

  Project: Research

• Immune Mechanisms in Psychiatric diseases: from systematic Analysis of Cohorts to Therapy (IMPACT)

  Dazzan, P. (Primary Investigator) & Pariante, C. (Co-Investigator)

  1/10/2015 → 31/12/2020

  Project: Research

• Understanding immune activation in severe mental illnesses: are current clinical diagnostic categories relevant for future drug treatment?

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/10/2015 → 30/09/2017

  Project: Research

• Evaluation of the glutamate system as a neurobiological marker for dissociation: A resting-state MRI study of trauma-related and induced dissociation

  Reinders, S. (Primary Investigator), Barker, G. (Co-Investigator), David, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Mehta, M. (Co-Investigator), Stone, J. (Co-Investigator) & Zelaya, F. (Co-Investigator)

  1/07/2015 → 30/06/2018

  Project: Research

• The neurobiology of trauma-related and induced dissociation: A resting-state MRI study in (dissociative) PTSD and healthy controls

  Reinders, S. (Primary Investigator), Barker, G. (Co-Investigator), Dazzan, P. (Co-Investigator) & Zelaya, F. (Co-Investigator)

  1/07/2015 → 30/06/2017

  Project: Research

• WATERFLAME

  Turkheimer, F. (Primary Investigator), Dazzan, P. (Co-Investigator), Pariante, C. (Co-Investigator) & Vernon, A. (Co-Investigator)

  1/03/2015 → 28/02/2020

  Project: Research

• TARGETING BRAIN INFLAMMATION IN DEPRESSION USING MINOCYCLINE: A STRATIFIED, RANDOMISED, PLACEBO-CONTROLLED, EXPERIMENTAL MEDICINE STUDY, INTEGRATING BEHAVIOUR, PET, MRI AND PERIPHERAL BIOMARKERS

  Pariante, C. (Primary Investigator), Barker, G. (Co-Investigator), Cash, D. (Co-Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Egeland, M. (Co-Investigator), Mondelli, V. (Co-Investigator), Turkheimer, F. (Co-Investigator), Tylee, A. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/03/2015 → 29/02/2020

  Project: Research

• Biological, social and clinical predictors of suicidal behaviour in first episode psychosis

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Murray, R. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/11/2014 → 31/10/2016

  Project: Research

• Using stress-related biomarkers to predict clinical outcomes in first episode psychosis

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Murray, R. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/11/2014 → 31/10/2016

  Project: Research

• Developing a biomarkets-based tool to predict treatment response in first-episode psychosis

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/10/2014 → 30/09/2017

  Project: Research

• Identification and evaluation of negative symptoms at the onset of psychosis prior to antipsychotic treatment: the prevalence, predictors and clinical outcome

  Demjaha, A. (Primary Investigator), Dazzan, P. (Co-Investigator) & McGuire, P. (Co-Investigator)

  1/09/2014 → 31/08/2017

  Project: Research

• Translating neuroimaging findings from research into clinical practice - PSYSCAN

  McGuire, P. (Primary Investigator), Brammer, M. (Co-Investigator), Dazzan, P. (Co-Investigator), Fusar-Poli, P. (Co-Investigator), Kempton, M. (Co-Investigator) & Mechelli, A. (Co-Investigator)

  EC European Commission

  1/02/2014 → 31/07/2021

  Project: Research

• Neurobiological predictors of Persistent Negative Symptoms in medication naive first episode psychosis sample

  Demjaha, A. (Primary Investigator), Dazzan, P. (Co-Investigator) & McGuire, P. (Co-Investigator)

  1/01/2014 → 31/12/2017

  Project: Research

• Inflammation and Psychosis : translating research findings into clincal practice

  Mondelli, V. (Primary Investigator), Bhattacharyya, S. (Co-Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/01/2014 → 31/12/2017

  Project: Research

• Neurobiological predictors of Persistent Negative Symptoms in medication naive first episode psychosis sample

  Demjaha, A. (Primary Investigator), Dazzan, P. (Co-Investigator) & McGuire, P. (Co-Investigator)

  1/12/2013 → 31/12/2018

  Project: Research

• Neurobiological predictors of Persistent Negative Symptoms in medication naive first episode psychosis sample

  Demjaha, A. (Primary Investigator), Dazzan, P. (Co-Investigator) & McGuire, P. (Co-Investigator)

  1/12/2013 → 31/12/2018

  Project: Research

• Inflammation and psychosis : translating research findings into clinical practise

  Mondelli, V. (Primary Investigator), Bhattacharyya, S. (Co-Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/12/2013 → 30/11/2018

  Project: Research

• Inflammation and psychosis: translating findings on biological mechanisms into clinical practice

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/11/2013 → 30/10/2016

  Project: Research

• Neuroinflammation in psychosis : a proof-of-concept mechanistic study of changes in myelin content and microglia activation using the anti-inflammatory, Minocycline

  Giordano, A. (Primary Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Neuroinflammation in psychosis : a proof-of-concept mechanistic study of changes in myelin content and microglia activation using the anti-inflammatory , Minocycline

  Giordano, A. (Primary Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Dissecting brain inflammation in depression : Integrating behaviour,PET,MRS,MRI,cytokines and transcriptomics

  Pariante, C. (Primary Investigator), Barker, G. (Co-Investigator), Cleare, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Dobson, R. (Co-Investigator), Hayday, A. (Co-Investigator), Hotopf, M. (Co-Investigator), Howes, O. (Co-Investigator), Kapur, S. (Co-Investigator), Pickles, A. (Co-Investigator), Rabiner, E. (Co-Investigator), Taylor, M. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Tylee, A. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• In search of the right medication for psychosis

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/09/2013 → 1/09/2014

  Project: Research

• The neurobiological basis of Puerperal Psychosis : how multiple systems interact with brain vulnerability.

  Dazzan, P. (Primary Investigator), Clement, S. (Co-Investigator), Craig, M. (Co-Investigator), Howard, L. (Co-Investigator), Mehta, M. (Co-Investigator), Pariante, C. (Co-Investigator), Pickles, A. (Co-Investigator), Price, J. (Co-Investigator), Srivastava, D. (Co-Investigator) & Williams, S. (Co-Investigator)

  Medical Research Foundation

  1/09/2013 → 31/01/2017

  Project: Research

• Identifying molecular predictors of treatment response in first-episode psychosis

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/08/2013 → 1/08/2015

  Project: Research

• Understanding the role of childhood trauma and neuroplasticity - Related pathways in the development of Depressive symptoms during first episode psychosis

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Morgan, C. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/03/2013 → 1/03/2014

  Project: Research

• A proof-of-concept neuroimaging study of the effects of the anti-inflammatory, Minocycline, on microglia activation in first episode psychosis

  Dazzan, P. (Primary Investigator), Howes, O. (Co-Investigator), Mondelli, V. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/03/2013 → 28/02/2016

  Project: Research

• The use of multimodal neuroimaging in first-episode psychosis to predict clinical outcome

  Dazzan, P. (Primary Investigator) & Reis Marques, T. (Primary Investigator)

  NARSAD National Alliance for Research on Schizophrenia and Depression

  15/01/2013 → 14/01/2015

  Project: Research

• Predicting clinical and functional outcomes in psychosis using machine learning.

  Patel, R. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Mechelli, A. (Co-Investigator) & Stewart, R. (Co-Investigator)

  MRC Medical Research Council

  14/01/2013 → 13/01/2016

  Project: Research

  • Patient 100%
  • Psychosis 79%
  • Hospital 78%
  • Therapeutic Procedure 62%
  • Bipolar Disorder 54%

• Predicting drug response in schizophrenia: are clinical & cognitive tests a cost-effective alternative to neuroimaging?

  Mechelli, A. (Primary Investigator), Brammer, M. (Co-Investigator), Dazzan, P. (Co-Investigator), Kapur, S. (Co-Investigator) & McGuire, P. (Co-Investigator)

  MRC Medical Research Council

  1/01/2013 → 31/12/2014

  Project: Research

• Improving physical health in mental health: identifying predictors of poor physical healh in patients with first episode psychosis

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/10/2012 → 30/09/2013

  Project: Research

• USING NEUROIMAGING TO GUIDE CLINICAL MANAGEMENT IN PSYCHIATRY:APPLYING PATTERN RECOGNITION ANALYSIS IN THE INDIVIDUALISED PREDICTION OF PSYCHOSIS OUTCOMe

  Dazzan, P. (Primary Investigator)

  1/10/2012 → 30/09/2013

  Project: Research

• Predicting clinical and functional outcome sin psychosis using machine learning

  Patel, R. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Mechelli, A. (Co-Investigator) & Stewart, R. (Co-Investigator)

  1/10/2012 → 30/09/2015

  Project: Research

• The role of stress and genetic predisposition in the development of psychosis

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Morgan, C. (Co-Investigator), Murray, R. (Co-Investigator), Pariante, C. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/10/2012 → 30/09/2017

  Project: Research

• Validating Individualise Prediction of Illness

  Dazzan, P. (Primary Investigator) & Williams, S. (Co-Investigator)

  15/07/2012 → 14/07/2014

  Project: Research

• How do genetic predisposition and environmental stressors act on the brain to increase the risk of psychosis?

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Morgan, C. (Co-Investigator), Murray, R. (Co-Investigator), Pariante, C. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/05/2012 → 1/05/2016

  Project: Research

• Evaluating the efficacy of adjunctive mincycline for the treatment of major depression: a proof-of-concept, randomised, placebo-controlled trial.

  Pariante, C. (Primary Investigator), Cleare, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Mondelli, V. (Co-Investigator), Pickles, A. (Co-Investigator), Taylor, M. (Co-Investigator), Tylee, A. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/04/2012 → 31/03/2014

  Project: Research

• Neurobiological determinants of treatment response in psychosis

  Howes, O. (Primary Investigator), Dazzan, P. (Co-Investigator), Egerton, A. (Co-Investigator), Kapur, S. (Co-Investigator) & McGuire, P. (Co-Investigator)

  Wellcome Trust

  5/03/2012 → 31/08/2017

  Project: Research