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  The role of Inositol (1,4,5)trisphosphate receptor 2 ( IP3R2) in platelet function, thrombus formation and vascular permeability

  Authi, K. (Primary Investigator), Fraser, P. (Co-Investigator) & Mann, G. (Co-Investigator)

  1/02/2017 → 31/01/2019

  Project: Research

• Nrf2-regulated redox signalling in brain endothelial cells adapted to physiological oxygen levels: consequences for ischaemia-reperfusion injury and protection by sulforaphane

  Mann, G. (Primary Investigator) & Fraser, P. (Co-Investigator)

  BHF British Heart Foundation

  1/10/2016 → 20/11/2019

  Project: Research

• The role of inositol (1,4,5) trisphosphate receptor 2 in platelet function, thrombus formation and vascular permeability

  Authi, K. (Primary Investigator), Fraser, P. (Co-Investigator) & Mann, G. (Co-Investigator)

  1/05/2016 → 1/04/2018

  Project: Research

• Therapeutic potential of sulforaphane in protection against blood-brain barrier breakdown and inflammation in experimental stroke

  Mann, G. (Primary Investigator) & Fraser, P. (Co-Investigator)

  BHF British Heart Foundation

  2/02/2015 → 5/02/2018

  Project: Research

• Improving outcome after stroke by targeting the Nrf2-Keap 1 pathway for neurovascular protection

  Mann, G. (Primary Investigator), Fraser, P. (Co-Investigator) & Siow, R. (Co-Investigator)

  1/09/2013 → 28/02/2014

  Project: Research

• Improving outcome after stroke by targeting the Nrf2-Keap1 pathway for neurovascular protection

  Mann, G. (Primary Investigator), Duchen, M. (Co-Investigator), Fraser, P. (Co-Investigator) & Siow, R. (Co-Investigator)

  1/09/2012 → 31/08/2013

  Project: Research

• Improving outcome after stroke by targeting the Nrf2-Keap1 pathway for neurovascaular protection

  Mann, G. (Primary Investigator), Duchen, M. (Co-Investigator), Fraser, P. (Co-Investigator) & Siow, R. (Co-Investigator)

  1/09/2012 → 31/08/2013

  Project: Research

• Angiopoietins in the maintenance of glomerular capillary permeability in health and disease

  Gnudi, L. (Primary Investigator), Bates, D. (Co-Investigator), Fraser, P. (Co-Investigator), Long, D. (Co-Investigator) & Salmon, A. (Co-Investigator)

  1/05/2010 → 30/04/2013

  Project: Research

• Improving the outcome of stroke targeting the Nrf2-Keap1 defence pathway for neurovascular protection

  Mann, G. (Primary Investigator), Fraser, P. (Co-Investigator) & Siow, R. (Co-Investigator)

  Henry Smith Charity

  1/10/2009 → 30/11/2014

  Project: Research

• The role of angiopoietin-1 and vascular endothelial growth factor in controlling glomerular capillary permeability

  Gnudi, L. (Primary Investigator), Bates, D. (Co-Investigator), Fraser, P. (Co-Investigator) & Long, D. (Co-Investigator)

  1/07/2009 → 30/06/2012

  Project: Research

• Modulation of blood-brain barrier with relevance to multiple sclerosis

  Abbott, J. (Primary Investigator) & Fraser, P. (Primary Investigator)

  1/01/2009 → 31/12/2010

  Project: Research

• The role of reactive oxygen species in the EDHF response

  Aaronson, P. (Primary Investigator) & Fraser, P. (Co-Investigator)

  BHF British Heart Foundation

  1/10/2008 → 30/09/2011

  Project: Research

• Modulation of the blood-brain barrier and cell:cell interation; relevance to multiplesclerosis

  Abbott, J. (Primary Investigator), Fraser, P. (Primary Investigator) & Couraud, P.-O. (Co-Investigator)

  1/10/2008 → 30/09/2010

  Project: Research

• The role of NF-KB activation microvascular permeability in stroke

  Chen, R. (Primary Investigator), Fraser, P. (Co-Investigator) & Pearson, J. (Co-Investigator)

  1/04/2008 → 31/03/2011

  Project: Research

• Rapid enhancement of interleukin-1 of endothelial cell responses to bradykinin in vivo and in cell culture

  Fraser, P. (Primary Investigator) & Pearson, J. (Co-Investigator)

  BHF British Heart Foundation

  1/11/2000 → 31/10/2003

  Project: Research

• Development of quantitative histochemical approach to investigate the mechanisms of cerebral oedema

  Fraser, P. (Primary Investigator)

  Wellcome Trust

  1/10/2000 → 30/09/2001

  Project: Research

• MEN 11270 pharmacological activity in ischaemia models in rats

  Fraser, P. (Primary Investigator)

  Menarini Academy

  1/01/2000 → 31/05/2000

  Project: Research

• The mechanisms of hormone secretion and interaction in endocrine pancreas studied using intravital fluorescence imaging and confocal microscopy

  Fraser, P. (Primary Investigator) & Pedley, K. (Primary Investigator)

  Wellcome Trust

  1/03/1998 → 28/02/2001

  Project: Research

• Role of kinins in the regulation of cerebrovascular permeability

  Fraser, P. (Primary Investigator)

  Sandoz Institute for Medical Research

  1/10/1996 → 30/09/1999

  Project: Research