Personal profile
Research interests
- Hybrid PET/MRI systems.
- Motion correction of PET images.
- Methodology, new tracers and data analysis for clinical and research PET studies, in oncology, cardiology and neuropsychiatry.
- The use of PET in multicentre trials to evaluate new therapies.
Biographical details
Paul Marsden has been involved in PET imaging for most of his career and has worked in all aspects of the field from the production of new radionuclides through to the development of clinical and research scanning protocols. He has a degree in physics at Oxford University, and a PhD in Medical Physics from the Institute of Cancer Research, University of London. His research track record includes the early development of combined PET and MRI imaging systems, data analysis methods for clinical and research PET studies, the development of radionuclide production methods and development of PET and PET-CT image acquisition methods. Much of this work is in collaboration with other clinical researchers in oncology, radiotherapy, cardiology and neuropsychiatry. As Scientific Director at Guy's and St Thomas' PET Centre, Paul is also familiar with the various regulatory, logistical and technical issues associated with clinical and research PET studies. He contributes regularly to many PET-related international meetings and committees and, with Dr Sally Barrington, runs the NCRI PET Research Network.
Education/Academic qualification
Doctor of Philosophy, Institute of Cancer Research
Award Date: 1 Jan 1987
Master of Science, University of Birmingham
Award Date: 1 Jan 1982
Bachelor of Arts, University of Oxford
Award Date: 1 Jan 1981
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 11 Sustainable Cities and Communities
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Collaborations and top research areas from the last five years
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Inter-individual variability of neurotransmitter receptor and transporter density in the human brain
Hansen, J. Y., Tuisku, J., Johansson, J., Chang, Z., McGinnity, C. J., Beliveau, V., Guimond, S., Ganz, M., Nørgaard, M., Galovic, M., Bezgin, G., Cox, S. M. L., Hietala, J., Leyton, M., Kobayashi, E., Rosa-Neto, P., Funck, T., Palomero-Gallagher, N., Knudsen, G. M. & Marsden, P. & 4 others, , 13 Jan 2026, (E-pub ahead of print) In: Brain Structure and Function. 231, 1, 13.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)3 Downloads (Pure) -
Initial results of the Hyperion II DPET insert for simultaneous PET-MRI applied to atherosclerotic plaque imaging in New-Zealand white rabbits.
Gebhardt, P., Lavin, B., Phinikaridou, A., Mackewn, J. E., Henningsson, M., Schug, D., Salomon, A., Marsden, P. K., Schulz, V. & Botnar, R., 16 Feb 2025, In: Physics in Medicine and Biology. 70, 4, 16 p., 045017.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Downloads (Pure) -
Machine learning to identify suitable boundaries for band-pass spectral analysis of dynamic [11C]Ro15-4513 PET scan and voxel-wise parametric map generation
Chang, Z., McGinnity, C., Hinz, R., Wang, M., Dunn, J., Liu, R., Yakubu, M., Marsden, P. & Hammers, A., 11 Jul 2025, In: EJNMMI Research. 15, 1, 14 p., 85.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)13 Downloads (Pure) -
Self-supervised parametric map estimation for multiplexed PET with a deep image prior
Pan, B., Marsden, P. & Reader, A., 31 Jan 2025, In: Physics in Medicine & Biology. 70, 4, 045002.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Deep learned triple-tracer multiplexed PET myocardial image separation
Pan, B., Marsden, P. & Reader, A., 11 Apr 2024, In: Frontiers in Nuclear Medicine. 4, 13 p., 1379647.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)11 Downloads (Pure)
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Next generation imaging with Total Body Positron Emission Tomography for whole body organ perfusion
Nazir, M. (Primary Investigator), Cook, G. (Co-Investigator), Hammers, A. (Co-Investigator), Lilburn, D. (Co-Investigator), Marsden, P. (Co-Investigator) & Subesinghe, M. (Co-Investigator)
31/03/2025 → 30/03/2028
Project: Research
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Evaluation of the quantitative accuracy and radiation dosimetry of an advanced pre-clinical multipinhole SPECT/CT theranostic imaging device
Marsden, P. (Primary Investigator), Witney, T. (Co-Investigator) & academic, A. (Co-Investigator)
Mediso Medical Imaging Systems UK
1/10/2023 → 30/09/2027
Project: Research
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National Total Body PET Centre
Hammers, A. (Primary Investigator), Barrington, S. (Co-Investigator), Blower, P. (Co-Investigator), Cook, G. (Co-Investigator), Gee, T. (Co-Investigator), Marsden, P. (Co-Investigator), Modat, M. (Co-Investigator), Nazir, M. (Co-Investigator), Ourselin, S. (Co-Investigator), Razavi, R. (Co-Investigator), Reader, A. (Co-Investigator) & Terry, S. (Co-Investigator)
1/10/2023 → 30/09/2030
Project: Research
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Wellcome/EPSRC Centre for Medical Engineering Extension
Ourselin, S. (Primary Investigator), Barker, G. (Co-Investigator), Barnes, A. (Co-Investigator), Barrington, S. (Co-Investigator), Bergeles, C. (Co-Investigator), Bishop, M. (Co-Investigator), Blower, P. (Co-Investigator), Booth, T. (Co-Investigator), Botnar, R. (Co-Investigator), Cardoso, J. (Co-Investigator), Carmichael, D. (Co-Investigator), Chiribiri, A. (Co-Investigator), Clough, R. (Co-Investigator), Cook, G. (Co-Investigator), Counsell, S. (Co-Investigator), Dasgupta, P. (Co-Investigator), De Vecchi, A. (Co-Investigator), De Vita, E. (Co-Investigator), Edwards, D. (Co-Investigator), Goh, V. (Co-Investigator), Hajnal, J. (Co-Investigator), Hammers, A. (Co-Investigator), Hutter, J. (Co-Investigator), Ipek, O. (Co-Investigator), King, A. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Liu, H. (Co-Investigator), Malik, S. (Co-Investigator), Marsden, P. (Co-Investigator), Modat, M. (Co-Investigator), Niederer, S. (Co-Investigator), Razavi, R. (Co-Investigator), Reader, A. (Co-Investigator), Rhode, K. (Co-Investigator), Roujol, S. (Co-Investigator), Rutherford, M. (Co-Investigator), Shapey, J. (Co-Investigator), Sparks, R. (Co-Investigator), T. M. de Rosales, R. (Co-Investigator), Terry, S. (Co-Investigator), Tournier, J.-D. (Co-Investigator), Vercauteren, T. (Co-Investigator), Williams, S. (Co-Investigator), Xia, W. (Co-Investigator), Young, A. (Co-Investigator) & academic, A. (Co-Investigator)
28/04/2022 → 27/10/2024
Project: Research
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Next generation molecular imaging and therapy with radionuclides
Blower, P. (Primary Investigator), Gee, T. (Co-Investigator), Ng, T. (Co-Investigator), Barrington, S. (Co-Investigator), T. M. de Rosales, R. (Co-Investigator), Ma, M. (Co-Investigator), Fruhwirth, G. (Co-Investigator), Southworth, R. (Co-Investigator), Reader, A. (Co-Investigator), Marsden, P. (Co-Investigator) & Terry, S. (Co-Investigator)
EPSRC Engineering and Physical Sciences Research Council
1/10/2019 → 30/09/2024
Project: Research
Activities
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IEEE Nuclear Medical and Imaging Sciences Council
Marsden, P. (Member)
2012 → 2014Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
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ECMC Imaging Group Steering Committee
Marsden, P. (Member)
Dec 2011 → Dec 2014Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
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IPEM
Marsden, P. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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IEEE
Marsden, P. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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BNMS
Marsden, P. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
Datasets
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Randomised high resolution 4D volumes synthesis
Chen, X., King, A., Prieto Vasquez, C., Balfour, D., Reader, A., Marsden, P., Usman, M. & Baumgartner, C., King's College London, 6 Dec 2016
DOI: 10.18742/rdm01-114, https://kcl.figshare.com/articles/dataset/Randomised_high_resolution_4D_volumes_synthesis/16473681
Dataset