Personal profile
Research interests
Molecular control of tooth development/tissue engineering and dental stem cells.
Research interests (short)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Wnt Signaling Regulates Pulp Volume and Dentin Thickness
Lim, W. H., Liu, B., Cheng, D., Hunter, D. J., Zhong, Z., Ramos, D. M., Williams, B. O., Sharpe, P. T., Bardet, C., Mah, S.-J. & Helms, J. A., Apr 2014, In: Journal of Bone and Mineral Research. 29, 4, p. 892-901 10 p., N/A.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
Adult Human Gingival Epithelial Cells as a Source for Whole-tooth Bioengineering
Angelova, A., Kawasaki, M. & Sharpe, P. T., Apr 2013, In: Journal of Dental Research. 92, 4, p. 329-334 6 p.Research output: Contribution to journal › Article › peer-review
84 Citations (Scopus) -
Glial origin of mesenchymal stem cells in a tooth model system
Kaukua, N., Shahidi, M. K., Konstantinidou, C., Dyachuk, V., Kaucka, M., Furlan, A., An, Z., Wang, L., Hultman, I., Ahrlund-Richter, L., Blom, H., Brismar, H., Lopes, N. A., Pachnis, V., Suter, U., Clevers, H., Thesleff, I., Sharpe, P., Ernfors, P. & Fried, K. & 1 others, , 25 Sept 2014, In: NATURE. 513, 7519, p. 551–554Research output: Contribution to journal › Article › peer-review
380 Citations (Scopus) -
Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor
Zhao, H., Feng, J., Seidel, K., Shi, S., Klein, O., Sharpe, P. & Chai, Y., 6 Feb 2014, In: Cell Stem Cell. 14, 2, p. 160-173 14 p.Research output: Contribution to journal › Article › peer-review
Open Access385 Citations (Scopus) -
Bone regeneration of rat calvarial defect using biomimetic keratin-based membranes
Gamea, S., Kaabi, H., Elredah, I., Aljohani, H., Horamee, S., Shaqrah, H. J. N. A., Lu, E., Hodgkinson, T., Balto, H., Sharpe, P. & Elsharkawy, S., Jul 2026, In: Biomaterials advances.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 71 Finished
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An Investigation Of Genetic Variation In Human Tooth Eruption Defects
Seppala, M. (Primary Investigator), Cobourne, M. (Co-Investigator) & Sharpe, P. (Co-Investigator)
EOS European Orthodontic Society
1/10/2021 → 28/02/2025
Project: Research
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Investigating periodontitis host-related factors at molecular level: healthy-to-diseased periodontium single-cell characterisation and molecular dynamics of aging
Neves, V. (Primary Investigator), Ide, M. (Co-Investigator), Nibali, L. (Co-Investigator) & Sharpe, P. (Co-Investigator)
15/03/2021 → 14/09/2023
Project: Research
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The key role of primary cilia in determining tooth morphogenesis
Sharpe, P. (Primary Investigator)
31/03/2020 → 30/03/2023
Project: Research
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Lithiated porous silicon nanoparticles for alveolar bone regeneration in periodontal disease
Chiappini, C. (Primary Investigator) & Sharpe, P. (Co-Investigator)
1/11/2019 → 30/11/2021
Project: Research
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ReDent: pre MHRA toxicology consultant
Sharpe, P. (Primary Investigator)
1/06/2019 → 31/08/2019
Project: Research
Activities
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J. Oral Biosciences (Journal)
Sharpe, P. (Editorial board member)
2007 → 2009Activity: Publication peer-review and editorial work › Editorial activity
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the Heath Grants Panel
Sharpe, P. (Member)
2006 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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NIH study section: Skeletal Biology Development and Disease, Committee
Sharpe, P. (Committee Member)
2005 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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Regenerative Medicine (Journal)
Sharpe, P. (Editorial board member)
2005 → …Activity: Publication peer-review and editorial work › Editorial activity
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ORAL BIOSCIENCES AND MEDICINE (Journal)
Sharpe, P. (Editorial board member)
2003 → …Activity: Publication peer-review and editorial work › Editorial activity