Research output per year
Research output per year
Personal profile
Research interests
- Structure-function studies of the p53 family of transcription factors and their role in cancer and other human diseases
- Protein stability, protein (mis)folding, aggregation and disease
- Protein-protein, protein-DNA interactions.
Research interests (short)
Structure-function studies of the p53 family of transcription factors and their role in cancer and other human diseases.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Science, Yeast-mediated biotransformation in aqueous and non-aqueous media, University of Waterloo
Award Date: 1 Jan 1993
Fingerprint
Dive into the research topics where Penka Nikolova is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
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Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies
Hagiwara, Y., Sieverling, L., Hanif, F., Anton, J., Dickinson, E. R., Bui, T. T. T., Andreeva, A., Barran, P. E., Cota, E. & Nikolova, P. V., 28 Apr 2016, In: Scientific Reports. 6, 1 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus) -
Insights into the Conformations of Three Structurally Diverse Proteins: Cytochrome c, p53, and MDM2, Provided by Variable-Temperature Ion Mobility Mass Spectrometry
Dickinson, E. R., Jurneczko, E., Pacholarz, K. J., Clarke, D. J., Reeves, M., Ball, K. L., Hupp, T., Campopiano, D., Nikolova, P. V. & Barran, P. E., 17 Mar 2015, In: Analytical Chemistry. 87, 6, p. 3231-3238 8 p.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
Probing the Conformational Diversity of Cancer-Associated Mutations in p53 with Ion-Mobility Mass Spectrometry
Jurneczko, E., Cruickshank, F., Porrini, M., Clarke, DJ., Campuzano, ID., Morris, M., Nikolova, P. V. & Barran, PE., 15 Apr 2013, In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 52, 16, p. 4370-4374 5 p., N/A.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
Structure and stability insights into tumour suppressor p53 evolutionary related proteins
Pagano, B., Jama, A., Martinez, P., Akanho, E., Bui, T. T. T., Drake, A. F., Fraternali, F. & Nikolova, P. V., 4 Oct 2013, In: PLoS ONE. 8, 10, 17 p., e76014.Research output: Contribution to journal › Article › peer-review
Open Access20 Citations (Scopus) -
Intrinsic disorder in proteins: a challenge for (un)structural biology met by ion mobility-mass spectrometry
Jurneczko, E., Cruickshank, F., Porrini, M., Nikolova, P., Campuzano, I. D. G., Morris, M. & Barran, P. E., Oct 2012, In: Biochemical Society Transactions. 40, 5, p. 1021-U372 8 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus)
Projects
- 11 Finished
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A crosstalk between p73 and APP processing and its role in the molecular mechanism(s) of ageing and neurodegeneration
1/10/2010 → 30/09/2013
Project: Research
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Molecular basis of apoptotic co-activation of p73 by ASPPs
Nikolova, P. & Cota, E.
1/04/2010 → 31/03/2013
Project: Research
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Structural and biochemical basis of the binding of ASPP family of proteins with the p53 homologous protein p73: implications for apoptosis
Nikolova, P. & Cota, E.
1/03/2010 → 28/02/2013
Project: Research
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Mechanism of interaction between p73 and ASPPs: Relevance for cancer
1/04/2009 → 31/03/2012
Project: Research
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Screening and optimization of the conditions for structural studies of p53 homolgous protein p73
Nikolova, P., Chen, Y. & Sutton, B.
1/10/2008 → 30/09/2009
Project: Research
Activities
- 10 Types of External academic engagement - Contribution to the work of national or international committees and working groups
- 9 Publication peer-review
- 8 Participation in conference
- 6 Types of Business and Community - Work on advisory panel to industry or government or non-government organisation
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More
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Reviewed BBSRC Research grants and and or fellowships
Penka Nikolova (Reviewer)
2014Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
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Reviewed research grants, Spanish Cancer Charity, Barcelona
Penka Nikolova (Reviewer)
2013Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
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PL o S One (Journal)
Penka Nikolova (Editor)
2011 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Reviewed manuscript for the Int. J of Andrology (Journal)
Penka Nikolova (Editor)
2010 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Reviewed manuscript for the Int. J of Odontology (Journal)
Penka Nikolova (Editor)
2010 → …Activity: Publication peer-review and editorial work › Publication peer-review
Prizes
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MRC of Canada Postdoctoral Research Fellow, Held at Cambridge University and MRC Centre for Protein Engineering, Cambridge, UK.
Nikolova, Penka (Recipient), 1996
Prize: Fellowship awarded competitively
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NSERC of Canada Postdoctoral Research Fellow Held at Univ. of British Columbia, Vancouver.
Nikolova, Penka (Recipient), 1994
Prize: Fellowship awarded competitively