Peter Parker
  • 10803
    Citations

Personal profile

Research interests

Interests are broadly based in defining signal transduction pathways, their action, functional status, prognostic and therapeutic potential in cancer. The research is particularly focused around the protein kinase C superfamily and growth factor receptor action and pathophysiology. As membrane and protein complex associated protein kinases, these signal transducers operate in spatially restricted compartments and serve highly localised roles in controlling signal outputs. Recent studies have focused on spatial and dynamic aspects of signalling propagated through and/or influenced by these kinases, including the conformational nature of nucleotide binding (and the influence of interventions at this binding site), single molecule analysis of growth factor receptor behaviour, controls acting on the HGF-cMet growth factor signalling pathway, integrin actions in migration, the localisation of signals during migration and general roles in proliferation and survival. Application of molecular insights derived from the studies on these kinases and the methods developed for this purpose are significant current objectives. This includes drug development activities, biomarker discovery and biomarker methodologies.

Research interests (short)

Signal transduction pathways, their functional status, prognostic and therapeutic potential in cancer.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, Biochemistry (Supervisor: Professor Sir Philip Randle), University of Oxford

Award Date: 1 Jan 1979

Master of Arts, University of Oxford

Award Date: 1 Jan 1976

Bachelor of Arts, Biochemistry, University of Oxford

Award Date: 1 Jan 1976

External positions

Senior Group Leader, Francis Crick Institute

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Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Sixth Element Advisory Board

    Peter Parker (Member)

    2012 → …

    Activity: OtherTypes of Business and Community - Work on advisory panel to industry or government or non-government organisation

  • Cancer Research UK IAG

    Peter Parker (Member)

    2012 → …

    Activity: OtherTypes of Business and Community - Work on advisory panel to industry or government or non-government organisation

  • MRC, TRG committee

    Peter Parker (Member)

    2011 → …

    Activity: OtherTypes of External academic engagement - Membership of external research organisation

  • MATWIN Advisory Board

    Peter Parker (Member)

    2010 → …

    Activity: OtherTypes of External academic engagement - Membership of external research organisation

  • Wellcome Trust, ERG7

    Peter Parker (Member)

    2010 → …

    Activity: OtherTypes of External academic engagement - Membership of external research organisation