Peter Jenner

2023

Future Directions for Developing Non-dopaminergic Strategies for the Treatment of Parkinson's Disease

Wamelen, D. J. V., Leta, V., Chaudhuri, K. R. & Jenner, P., 31 Jul 2023, (E-pub ahead of print) In: Current Neuropharmacology.

Research output: Contribution to journal › Article › peer-review

Gastrointestinal barriers to levodopa transport and absorption in Parkinson's disease

International Parkinson and Movement Disorders Society Non-Motor Parkinson's Disease Study Group, May 2023, In: European Journal of Neurology. 30, 5, p. 1465-1480 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

28 Citations (Scopus)

2022

Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease: Past, Present, and Future

Tan, Y. Y., Jenner, P. & Chen, S. D., 2022, In: Journal of Parkinson's Disease. 12, 2, p. 477-493 17 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

84 Citations (Scopus)

The Pharmacological Potential of Adenosine A _2A Receptor Antagonists for Treating Parkinson's Disease

Mori, A., Chen, J-F., Uchida, S., Durlach, C., King, S. M. & Jenner, P., 6 Apr 2022, In: Molecules (Basel, Switzerland). 27, 7, 2366.

Research output: Contribution to journal › Article › peer-review

Open Access

File

26 Citations (Scopus)

228 Downloads (Pure)

Why do 'OFF' periods still occur during continuous drug delivery in Parkinson's disease?

Rota, S., Urso, D., van Wamelen, D. J., Leta, V., Boura, I., Odin, P., Espay, A. J., Jenner, P. & Chaudhuri, K. R., 13 Oct 2022, In: Translational Neurodegeneration. 11, 1, p. 43

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

2021

Dysregulation of epithelial ion transport and neurochemical changes in the colon of a parkinsonian primate.

Coletto, E., Tough, I. R., Pritchard, S., Hikima, A., Jackson, M., Jenner, P., Chaudhuri, K., Cox, H., Iravani, MM. & Salvage, S., 23 Jan 2021, In: Nature Parkinson's Journal. 7, 1, 9 p., 1.

Research output: Contribution to journal › Editorial › peer-review

Open Access

3 Citations (Scopus)

Istradefylline–a first generation adenosine A_2A antagonist for the treatment of Parkinson’s disease

Jenner, P., Mori, A., Aradi, S. D. & Hauser, R. A., 2021, In: Expert Review of Neurotherapeutics. 21, 3, p. 317-333 17 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

56 Citations (Scopus)

Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease

EUROPAR and the International Parkinson and Movement Disorders Society Non-Motor Parkinson’s Disease Study Group, Dec 2021, In: npj Parkinson's Disease. 7, 1, 48.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

Redefining the strategy for the use of COMT inhibitors in Parkinson’s disease: the role of opicapone

Jenner, P., Rocha, J. F., Ferreira, J. J., Rascol, O. & Soares-da-Silva, P., 2021, In: Expert Review of Neurotherapeutics. 21, 9, p. 1019-1033 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Citations (Scopus)

Rotigotine Transdermal Patch for Motor and Non-motor Parkinson’s Disease: A Review of 12 Years’ Clinical Experience

Raeder, V., Boura, I., Leta, V., Jenner, P., Reichmann, H., Trenkwalder, C., Klingelhoefer, L. & Chaudhuri, K. R., Feb 2021, In: CNS Drugs. 35, 2, p. 215-231 17 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

27 Citations (Scopus)

2020

Beneficial effect of 24-month bilateral subthalamic stimulation on quality of sleep in Parkinson’s disease

EUROPAR, the IPMDS Non Motor P.D. Study Group, 1 Jun 2020, In: Journal of Neurology. 267, 6, p. 1830-1841 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (Scopus)

Can adenosine A_2A receptor antagonists be used to treat cognitive impairment, depression or excessive sleepiness in Parkinson's disease?

Jenner, P., Mori, A. & Kanda, T., Nov 2020, In: Parkinsonism and Related Disorders. 80, p. S28-S36

Research output: Contribution to journal › Article › peer-review

Open Access

23 Citations (Scopus)

Can adenosine A_2A receptor antagonists modify motor behavior and dyskinesia in experimental models of Parkinson's disease?

Kanda, T. & Jenner, P., Nov 2020, In: Parkinsonism and Related Disorders. 80, p. S21-S27

Research output: Contribution to journal › Article › peer-review

Open Access

16 Citations (Scopus)

Dyskinesia Matters: But Not as Much as It Used to

Chaudhuri, K. R., Jenner, P. & Antonini, A., 1 May 2020, In: Movement Disorders. 35, 5, p. 900-901 2 p.

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

Improving the Delivery of Levodopa in Parkinson’s Disease: A Review of Approved and Emerging Therapies

Urso, D., Chaudhuri, K. R., Qamar, M. A. & Jenner, P., Nov 2020, In: CNS Drugs. 34, 11, p. 1149-1163 15 p.

Research output: Contribution to journal › Review article › peer-review

29 Citations (Scopus)

Metformin as a Potential Neuroprotective Agent in Prodromal Parkinson's Disease—Viewpoint

Sportelli, C., Urso, D., Jenner, P. & Chaudhuri, K. R., 12 Jun 2020, In: Frontiers in Neurology. 11, 556.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Citations (Scopus)

Serum Uric Acid Levels and Non-Motor Symptoms in Parkinson's Disease

Van Wamelen, D. J., Taddei, R. N., Calvano, A., Titova, N., Leta, V., Shtuchniy, I., Jenner, P., Martinez-Martin, P., Katunina, E. & Chaudhuri, K. R., 1 Jan 2020, In: Journal of Parkinson's Disease. 10, 3, p. 1003-1010 8 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Stress and cortisol in Parkinson's disease

van Wamelen, D. J., Wan, Y. M., Ray Chaudhuri, K. & Jenner, P., 2020, International Review of Neurobiology. Clow, A. & Smyth, N. (eds.). ACADEMIC PRESS INC, p. 131-156 26 p. (International Review of Neurobiology; vol. 152).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

24 Citations (Scopus)

‘Dopamine agonist Phobia’ in Parkinson’s disease: when does it matter? Implications for non-motor symptoms and personalized medicine

Rota, S., Boura, I., Batzu, L., Titova, N., Jenner, P., Falup-Pecurariu, C. & Chaudhuri, K. R., 1 Sept 2020, In: Expert Review of Neurotherapeutics. 20, 9, p. 953-965 13 p.

Research output: Contribution to journal › Review article › peer-review

8 Citations (Scopus)

2019

Can therapeutic strategies prevent and manage dyskinesia in Parkinson’s disease? An update

Leta, V., Jenner, P., Chaudhuri, K. R. & Antonini, A., 2 Dec 2019, In: Expert Opinion On Drug Safety. 18, 12, p. 1203-1218 16 p.

Research output: Contribution to journal › Review article › peer-review

31 Citations (Scopus)

Contractile dysfunction and nitrergic dysregulation in small intestine of a primate model of Parkinson's disease

Coletto, E., Dolan, J. S., Pritchard, S., Gant, A., Hikima, A., Jackson, M. J., Benham, C. D., Ray Chaudhuri, K., Rose, S., Jenner, P. & Iravani, M. M., 25 Jun 2019, In: Nature Parkinson's Journal. 5, 10 p., 31231674.

Research output: Contribution to journal › Article › peer-review

Open Access

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16 Citations (Scopus)

117 Downloads (Pure)

Should there be less emphasis on levodopa-induced dyskinesia in Parkinson's disease?

Chaudhuri, K. R., Jenner, P. & Antonini, A., 1 Jun 2019, In: Movement Disorders. 34, 6, p. 816-819 4 p.

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Subacute administration of both methcathinone and manganese causes basal ganglia damage in mice resembling that in methcathinone abusers

Asser, A., Hikima, A., Raki, M., Bergström, K., Rose, S., Juurmaa, J., Krispin, V., Muldmaa, M., Lilles, S., Rätsep, H., Jenner, P., Kõks, S., Männistö, P. T. & Taba, P., 30 Nov 2019, (E-pub ahead of print) In: Journal of Neural Transmission.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

2018

Apomorphine infusion in advanced Parkinson disease

Antonini, A. & Jenner, P., 2 Nov 2018, In: Nature Reviews Neurology.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

The treatment of levodopa-induced dyskinesias: Surfing the serotoninergic wave

Jenner, P., 30 Nov 2018, In: Movement Disorders. 33, 11, p. 1670-1672 3 p.

Research output: Contribution to journal › Editorial › peer-review

7 Citations (Scopus)

2017

A glimmer of light at the end of the tunnel?

Jenner, P., 1 Oct 2017, In: Movement disorders : official journal of the Movement Disorder Society. 32, 10, p. 1343-1344 2 p.

Research output: Contribution to journal › Editorial › peer-review

Altered detrusor contractility in MPTP-treated common marmosets with bladder hyperreflexia

Pritchard, S., Jackson, M. J., Hikima, A., Lione, L., Benham, C. D., Chaudhuri, K. R., Rose, S., Jenner, P. & Iravani, M. M., 17 May 2017, In: PL o S One . 12, 5, e0175797.

Research output: Contribution to journal › Article › peer-review

Open Access

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12 Citations (Scopus)

213 Downloads (Pure)

Animal models of movement disorders

Duty, S. & Jenner, P., 1 Jan 2017, Movement Disorders Curricula. Springer-Verlag Wien, p. 11-21 11 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Cystatin C as a potential therapeutic mediator against Parkinson's disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units

Zou, J., Chen, Z., Wei, X., Chen, Z., Fu, Y., Yang, X., Chen, D., Wang, R., Jenner, P., Lu, J. H., Li, M., Zhang, Z., Tang, B., Jin, K. & Wang, Q., 1 Jun 2017, In: Cell death & disease. 8, 6, p. e2854

Research output: Contribution to journal › Article › peer-review

Open Access

88 Citations (Scopus)

Hallmarks of Treatment Aspects: Parkinson's Disease Throughout Centuries Including l-Dopa

Kim, H. J., Jeon, B. S. & Jenner, P., 20 Mar 2017, (E-pub ahead of print) In: International Review of Neurobiology.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease

Modo, M., Crum, W. R., Gerwig, M., Vernon, A. C., Patel, P., Jackson, M. J., Rose, S., Jenner, P. & Iravani, M. M., 24 Jul 2017, In: PLoS ONE. 12, 7, p. 1-21 e0180733.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

231 Downloads (Pure)

New Symptomatic Treatments for the Management of Motor and Nonmotor Symptoms of Parkinson's Disease

Taddei, R. N., Spinnato, F. & Jenner, P., 16 May 2017, (E-pub ahead of print) In: International Review of Neurobiology. 132, p. 407–452

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Non-motor features of Parkinson disease

Schapira, A. H. V., Chaudhuri, K. R. & Jenner, P., 1 Jul 2017, In: NATURE REVIEWS NEUROSCIENCE. 18, 7, p. 435-450 16 p.

Research output: Contribution to journal › Review article › peer-review

1166 Citations (Scopus)

Nonmotor Symptoms in Experimental Models of Parkinson's Disease

Titova, N., Schapira, A. H. V., Chaudhuri, K. R., Qamar, M. A., Katunina, E. & Jenner, P., 10 Jul 2017, (E-pub ahead of print) In: International Review of Neurobiology.

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

The future of parkinson’s treatment – Personalised and precision medicine

Titova, N., Jenner, P. & Ray Chaudhuri, K., 1 Jun 2017, In: European Neurological Review. 12, 1, p. 15-16 2 p.

Research output: Contribution to journal › Editorial › peer-review

Open Access

File

7 Citations (Scopus)

363 Downloads (Pure)

Two hundred years since James Parkinson's essay on the shaking palsy—Have we made progress? Insights from the James Parkinson's 200 years course held in London, March 2017

Chaudhuri, K. R. & Jenner, P., 11 Aug 2017, (E-pub ahead of print) In: Movement disorders : official journal of the Movement Disorder Society. 32, 9, p. 1311-1315 5 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

2016

Apomorphine - pharmacological properties and clinical trials in Parkinson's disease

Jenner, P. & Katzenschlager, R., 13 Dec 2016, (E-pub ahead of print) In: Parkinsonism & Related Disorders. 9 p.

Research output: Contribution to journal › Article › peer-review

83 Citations (Scopus)

Non motor subtypes and Parkinson's disease

Sauerbier, A., Jenner, P., Todorova, A. & Chaudhuri, K. R., Jan 2016, In: Parkinsonism & Related Disorders. 22, Supplement 1, p. S41-S46 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

268 Citations (Scopus)

1199 Downloads (Pure)

Non-oral dopaminergic therapies for Parkinson’s disease: current treatments and the future

Ray Chaudhuri, K., Qamar, M. A., Rajah, T., Loehrer, P., Sauerbier, A., Odin, P. & Jenner, P., 1 Dec 2016, In: npj Parkinson's Disease. 2, 1, 16023.

Research output: Contribution to journal › Review article › peer-review

Open Access

47 Citations (Scopus)

Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets

Lincoln, L., Fisher, R., Jackson, M. J., Jenner, P., Neumeyer, J., Sromek, A. W., Lees, A. J. & Salvage, S., 7 Sept 2016, In: Movement disorders : official journal of the Movement Disorder Society. 31, 9, p. 1381-1388 8 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Parkinson's Inside Out

Stamford, J., Scheller, D. & Jenner, P., 30 Mar 2016, In: Journal of Parkinson's Disease. 6, 1, p. 65-66 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

1 Citation (Scopus)

2015

Increased neurotrophic factor levels in ventral mesencephalic cultures do not explain the protective effect of osteopontin and the synthetic 15-mer RGD domain against MPP + toxicity

Broom, L., Jenner, P. & Rose, S., Jan 2015, In: Experimental Neurology. 263, p. 1-7 7 p., 00144886.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Inhibition of i-NOS but not n-NOS protects rat primary cell cultures against MPP+-induced neuronal toxicity

Brzozowski, M. J., Jenner, P. & Rose, S., 1 Jun 2015, In: Journal of Neural Transmission. 122, 6, p. 779-788 9 p., 10.1007/s00702-014-1334-8.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

The adenosine A_2A receptor antagonist, istradefylline enhances anti-parkinsonian activity induced by combined treatment with low doses of L-DOPA and dopamine agonists in MPTP-treated common marmosets

Uchida, S., Soshiroda, K., Okita, E., Kawai-Uchida, M., Mori, A., Jenner, P. & Kanda, T., 5 Nov 2015, In: European Journal of Pharmacology. 766, p. 25-30 6 p.

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

The adenosine A_2A receptor antagonist, istradefylline enhances the anti-parkinsonian activity of low doses of dopamine agonists in MPTP-treated common marmosets

Uchida, S. I., Soshiroda, K., Okita, E., Kawai-Uchida, M., Mori, A., Jenner, P. & Kanda, T., 15 Jan 2015, In: European Journal of Pharmacology. 747, p. 160-165 6 p.

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

The story of istradefylline-the first approved A_2A antagonist for the treatment of parkinson's disease

Mori, A., LeWitt, P. & Jenner, P., 9 Oct 2015, The Adenosinergic System: A Non-Dopaminergic Target in Parkinson's Disease. Springer International Publishing Switzerland, p. 273-289 17 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review