Research output per year
Research output per year
Personal profile
Research interests
Genetics of normal and abnormal behaviour including psychiatric disorders such as depression, schizophrenia and conduct disorders; research encompasses quantitative and molecular genetic approaches as well as the co-action and interaction of genes and environment.
Research interests (short)
Psychiatry, statistical and molecular genetics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Genetic markers in schzophrenia, University of London
Award Date: 1 Jan 1984
Bachelor of Medicine and Bachelor of Surgery, University of Leeds
Award Date: 1 Jan 1972
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., Su, M-H., Watson, H. J., Adams, M., Awasthi, S., Gandal, M., Hafferty, J. D., Hishimoto, A., Kim, M., & 33 others, 1 Feb 2022, In: Biological psychiatry. 91, 3, p. 313-327 15 p.Research output: Contribution to journal › Article › peer-review
Open Access111 Citations (Scopus) -
Identifying the Common Genetic Basis of Antidepressant Response
GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2022, In: Biological Psychiatry Global Open Science. 2, 2, p. 115-126 12 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Citations (Scopus) -
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Nov 2021, In: Biological psychiatry. 90, 9, p. 611-620 10 p.Research output: Contribution to journal › Article › peer-review
95 Citations (Scopus) -
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jun 2021, In: Molecular Psychiatry. 26, 6, p. 2457-2470 14 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
Dimensions of temperament and character as predictors of antidepressant discontinuation, response and adverse reactions during treatment with nortriptyline and escitalopram
Köhler-Forsberg, O., Keers, R., Uher, R., Hauser, J., Maier, W., Rietschel, M., McGuffin, P., Farmer, A. E., Aitchison, K. J. & Mors, O., 12 Nov 2021, (E-pub ahead of print) In: Psychological Medicine. p. 1-9Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)
Projects
- 66 Finished
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The Brazilian Bipolar Family Study : A 5 year follow-up study and molecular characterisation of phenotypes and mutations
Breen, G., McGuffin, P. & Weale, M.
1/04/2014 → 31/03/2017
Project: Research
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Investigating functional exonic genetic variants in antidepressant response
Tansey, K., Breen, G., McGuffin, P. & Uher, R.
15/01/2013 → 15/01/2014
Project: Research
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Stress and major depression : the role of epigenetic change in inflammatory pathways
Howes, O., Cohen-Woods, S., Fernandes, C., McGuffin, P. & Mill, J.
1/01/2013 → 31/12/2015
Project: Research
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Whole genome and exome sequencing of families with bipolar disorder and depression.
Breen, G., McGuffin, P. & academic, A.
1/12/2012 → 1/12/2014
Project: Research
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MICA Application of Genome-wide epigenetics to improve prediction of antidepressants treatment response in major depressive disorder.
Uher, R., Lewis, C., McGuffin, P., Mill, J. & Tansey, K.
1/09/2012 → 28/02/2015
Project: Research