Research output per year
Research output per year
- 28 results
Search results
-
2022
Angiotensin type 2 receptor antagonism as a new target to manage gout
Vieira, T. N., Saraiva, A. L. L., Guimarães, R. M., Luiz, J. P. M., Pinto, L. G., de Melo Rodrigues Ávila, V., Goulart, L. R., Cunha-Junior, J. P., McNaughton, P. A., Cunha, T. M., Ferreira, J. & Silva, C. R., 29 Sept 2022, In: Inflammopharmacology. 30, 6, p. 2399-2410 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure) -
Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release: Artemisinin inhibits neutrophil chemotaxis, cytokine and NET release
McNaughton, P., 21 Jun 2022, (Accepted/In press) In: Scientific Reports.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
HCN2 Ion Channels Drive Pain in Rodent Models of Migraine
Tsantoulas, C., Ng, A., Pinto, L., Andreou, A. P. & McNaughton, P. A., 5 Oct 2022, In: Journal of Neuroscience. 42, 40, p. 7513-7529 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Hidden Multivalency in Phosphatase Recruitment by a Disordered AKAP Scaffold: Hidden multivalency in a disordered scaffold
Watson, M., Almeida, T. B., Ray, A., Hanack, C., Elston, R., Btesh, J., McNaughton, P. A. & Stott, K., 30 Aug 2022, In: Journal of Molecular Biology. 434, 16, 167682.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
STIM1 and ORAI1 form a novel cold transduction mechanism in sensory and sympathetic neurons
Buijs, T. J., Vilar, B., Tan, C. H. & McNaughton, P. A., 2022, (Accepted/In press) In: EMBO Journal.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
2021
Blockade of bradykinin receptors or angiotensin II type 2 receptor prevents paclitaxel-associated acute pain syndrome in mice
Zanata, G. C., Pinto, L. G., da Silva, N. R., Lopes, A. H. P., de Oliveira, F. F. B., Schivo, I. R. S., Cunha, F. Q., McNaughton, P., Cunha, T. M. & Silva, R. L., Jan 2021, In: European Journal of Pain (United Kingdom). 25, 1, p. 189-198 10 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Oligodendrocyte hcn2 channels regulate myelin sheath length
Swire, M., Assinck, P., McNaughton, P. A., Lyons, D. A., Ffrench-Constant, C. & Livesey, M. R., 22 Sept 2021, In: Journal of Neuroscience. 41, 38, p. 7954-7964 11 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
Salicylate decreases the spontaneous firing rate of guinea pig auditory nerve fibres
Wallace, M. N., Sumner, C. J., Berger, J. I., McNaughton, P. A. & Palmer, A. R., 16 Mar 2021, In: Neuroscience Letters. 747, 135705.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
TRPM2 ion channels steer neutrophils towards a source of hydrogen peroxide: TRPM2 ion channels steer neutrophils
Morad, H., Luqman, S., Tan, C. H., Swann, V. & McNaughton, P., 31 Mar 2021, (Accepted/In press) In: Scientific Reports.Research output: Contribution to journal › Article › peer-review
Open AccessFile52 Downloads (Pure) -
2020
Heat detection by the TRPM2 ion channel
Vilar, B., Tan, C. H. & McNaughton, P., 12 Aug 2020, In: NATURE. 584, p. E5–E12 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Downloads (Pure) -
Imbalance of pro-resolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis
Malcangio, M., Allen, B., Montague-Cardoso, K., Simeoli, R., Colas, R. A., Oggero, S., Villar, B., McNaughton, P., Dalli, J., Perretti, M. & Sher, E., 23 Apr 2020, (Accepted/In press) In: Pain.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)43 Downloads (Pure) -
2019
A randomised, double-blind, placebo-controlled crossover trial of the influence of the HCN channel blocker ivabradine in a healthy volunteer pain model: an enriched population trial
Lee, M. C., Bond, S., Wheeler, D., Scholtes, I., Armstrong, G., McNaughton, P. & Menon, D., 1 Nov 2019, In: Pain. 160, 11, p. 2554-2565 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)81 Downloads (Pure) -
HCN3 ion channels - roles in sensory neuronal excitability and pain: HCN3 ion channels and pain
Lainez, S., Tsantoulas, C., Biel, M. & McNaughton, P. A., 1 Sept 2019, In: The Journal of Physiology. 597, 17, p. 4661-4675 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)82 Downloads (Pure) -
2017
Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy
Tsantoulas, C., Lainez, S., Wong, S., Mehta, I., Vilar, B. & McNaughton, P. A., 27 Sept 2017, In: Science Translational Medicine. 9, 409, 13 p., eaam6072.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)92 Downloads (Pure) -
2016
Agonist-induced sensitisation of the irritant receptor ion channel TRPA1
Meents, J. E., Fischer, M. J. M. & McNaughton, P. A., 15 Nov 2016, In: The Journal of Physiology. 594, 22, p. 6643-6660Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)92 Downloads (Pure) -
HCN2 ion channels: Basic science opens up possibilities for therapeutic intervention in neuropathic pain
Tsantoulas, C., Mooney, E. R. & McNaughton, P. A., 2016, In: Biochemical Journal. 473, 18, p. 2717-2736 20 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
2014
Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels
Young, G. T., Emery, E. C., Mooney, E. R., Tsantoulas, C. & McNaughton, P. A., 1 Sept 2014, In: Pain. 155, 9, p. 1708-1719 12 p.Research output: Contribution to journal › Article › peer-review
81 Citations (Scopus) -
2013
Disrupting Sensitization of Transient Receptor Potential Vanilloid Subtype 1 Inhibits Inflammatory Hyperalgesia
Fischer, M. J. M., Btesh, J. & McNaughton, P., 24 Apr 2013, In: Journal of Neuroscience. 33, 17, p. 7407-7414 8 p., N/A.Research output: Contribution to journal › Article › peer-review
64 Citations (Scopus) -
Mapping the Binding Site of TRPV1 on AKAP79: Implications for Inflammatory Hyperalgesia
Btesh, J., Fischer, M. J. M., Stott, K. & McNaughton, P. A., 22 May 2013, In: Journal of Neuroscience. 33, 21, p. 9184-9193 11 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
2012
Direct inhibition of the cold-activated TRPM8 ion channel by Gαq
Zhang, X., Mak, S., Li, L., Parra, A., Denlinger, B., Belmonte, C. & McNaughton, P. A., Aug 2012, In: Nature Cell Biology. 14, 8, p. 850-858 20 p.Research output: Contribution to journal › Article › peer-review
123 Citations (Scopus) -
Magnetic characterization of isolated candidate vertebrate magnetoreceptor cells
Eder, S. H. K., Cadiou, H., Muhamad, A., McNaughton, P., Kirschvink, J. L. & Winklhofer, M., 24 Jul 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 30, p. 12022-12027 6 p., N/A.Research output: Contribution to journal › Article › peer-review
98 Citations (Scopus) -
2011
HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain
Emery, E. C., Young, G. T., Berrocoso, E. M., Chen, L. & McNaughton, P., 9 Sept 2011, In: Science. 333, 6048, p. 1462-1466 5 p.Research output: Contribution to journal › Article › peer-review
260 Citations (Scopus) -
2010
Modulation of single-channel properties of TRPV1 by phosphorylation
Studer, M. & McNaughton, P., 1 Oct 2010, In: The Journal of Physiology. 588, 19, p. 3743-3756 14 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Citations (Scopus) -
Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones
Vellani, V., Kinsey, A. M., Prandini, M., Hechtfischer, S. C., Reeh, P., Magherini, P. C., Giacomoni, C. & McNaughton, P., 27 Sept 2010, In: Molecular Pain. 6, N/A, p. N/A 17 p., 61.Research output: Contribution to journal › Article › peer-review
Open Access67 Citations (Scopus) -
2009
Activation of the TRPV4 Ion Channel Is Enhanced by Phosphorylation
Fan, H-C., Zhang, X. & McNaughton, P., 9 Oct 2009, In: Journal of Biological Chemistry. 284, 41, p. 27884-27891 8 p., N/A.Research output: Contribution to journal › Article › peer-review
146 Citations (Scopus) -
2008
Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin
Vellani, V., Petrosino, S., De Petrocellis, L., Valenti, M., Prandini, M., Magherini, P. C., McNaughton, P. & Di Marzo, V., Dec 2008, In: Neuropharmacology. 55, 8, p. 1274-1279 6 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150
Zhang, X., Li, L. & McNaughton, P. A., 14 Aug 2008, In: Neuron. 59, 3, p. 450-461 12 p.Research output: Contribution to journal › Article › peer-review
Open Access224 Citations (Scopus) -
Role of the hyperpolarization-activated current I-h in somatosensory neurons
Momin, A., Cadiou, H., Mason, A. & McNaughton, P., Dec 2008, In: The Journal of Physiology. 586, 24, p. 5911-5929 19 p.Research output: Contribution to journal › Article › peer-review
Open Access126 Citations (Scopus)