King's College London

Research portal

Dr Petra Proitsi

  1. A genome-wide association study of plasma phosphorylated tau181

    Lord, J., Zettergren, A., Ashton, N., Karkari, T., Benedet, A., Simren, J., Hye, A., Aarsland, D., Zetterberg, H., Blennow, K. & Proitsi, P., May 2021, In: Neurobiology of Aging.

    Research output: Contribution to journalArticlepeer-review

  2. Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging Initiative

    Zettergren, A., Lord, J., Ashton, N., Benedet, A., Karikari, T., Lantero Rodriguez, J., Snellman, A., Suarez-Calvet, M., Proitsi, P., Zetterberg, H. & Blennow, K., 8 Jan 2021, In: Alzheimer's Research & Therapy. 13, 1, 17.

    Research output: Contribution to journalArticlepeer-review

  3. Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

    Kim, M., Snowden, S., Suvitaival, T., Ali, A., Merkler, D. J., Ahmad, T., Westwood, S., Baird, A., Proitsi, P., Nevado-Holgado, A., Hye, A., Bos, I., Vos, S., Vandenberghe, R., Teunissen, C., Ten Kate, M., Scheltens, P., Gabel, S., Meersmans, K., Blin, O. & 31 others, Richardson, J., De Roeck, E., Sleegers, K., Bordet, R., Rami, L., Kettunen, P., Tsolaki, M., Verhey, F., Sala, I., Lléo, A., Peyratout, G., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Popp, J., Martinez-Lage, P., Bertram, L., Barkhof, F., Ashton, N., Blennow, K., Zetterberg, H., Streffer, J., Visser, P. J., Lovestone, S. & Legido-Quigley, C., Jun 2019, In: Alzheimer's & Dementia. 15, 6, p. 817-827 11 p.

    Research output: Contribution to journalArticlepeer-review

  4. Metabolomic correlates of central adiposity and earlier-life body mass index

    Wulaningsih, W., Proitsi, P., Wong, A., Kuh, D. & Hardy, R., 18 Mar 2019, In: Journal of Lipid Research. 60, 6, p. 1136-1143 8 p.

    Research output: Contribution to journalArticlepeer-review

  5. Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

    Jansen, I. E., Savage, J. E., Watanabe, K., Bryois, J., Williams, D. M., Steinberg, S., Sealock, J., Karlsson, I. K., Hägg, S., Athanasiu, L., Voyle, N., Proitsi, P., Witoelar, A., Stringer, S., Aarsland, D., Almdahl, I. S., Andersen, F., Bergh, S., Bettella, F., Bjornsson, S. & 33 others, Brækhus, A., Bråthen, G., de Leeuw, C., Desikan, R. S., Djurovic, S., Dumitrescu, L., Fladby, T., Hohman, T. J., Jonsson, P. V., Kiddle, S. J., Rongve, A., Saltvedt, I., Sando, S. B., Selbæk, G., Shoai, M., Skene, N. G., Snaedal, J., Stordal, E., Ulstein, I. D., Wang, Y., White, L. R., Hardy, J., Hjerling-Leffler, J., Sullivan, P. F., van der Flier, W. M., Dobson, R., Davis, L. K., Stefansson, H., Stefansson, K., Pedersen, N. L., Ripke, S., Andreassen, O. A. & Posthuma, D., 1 Mar 2019, In: Nature Genetics. 51, 3, p. 404-413 10 p.

    Research output: Contribution to journalArticlepeer-review

  6. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

    Alzheimer Disease Genetics Consortium (ADGC), Mar 2019, In: Nature Genetics. 51, 3, p. 414-430 17 p.

    Research output: Contribution to journalArticlepeer-review

  7. S34INVESTIGATING THE ROLE OF BLOOD METABOLITES AS BIOMARKERS OF COGNITIVE FUNCTION AND DEMENTIA IN THE MRC 1946 BRITISH BIRTH COHORT

    Green, B., Lord, J., Xu, J., Maddock, J., Kim, M. G., Dobson, R., Legido-Quigley, C., Wong, A., Richards, M. & Proitsi, P., 2019, European Neuropsychopharmacology.

    Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

  8. Analysis of shared heritability in common disorders of the brain

    Brainstorm Consortium, 22 Jun 2018, In: Science. 360, 6395

    Research output: Contribution to journalArticlepeer-review

  9. Lifetime cognition and midlife blood metabolites: findings from a British birth cohort

    Proitsi, P., Kuh, D., Wong, A., Maddock, J., Bendayan, R., Wulaningsih, W., Hardy, R. & Richards, M., 2018, (Accepted/In press) In: Translational psychiatry.

    Research output: Contribution to journalArticlepeer-review

  10. Rheumatoid arthritis and risk for Alzheimer's disease: A systematic review and meta-analysis and a Mendelian Randomization study

    Policicchio, S., Ahmad, A. N., Powell, J. & Proitsi, P., 1 Dec 2017, In: Scientific Reports. 7, 1, 12861.

    Research output: Contribution to journalArticlepeer-review

  11. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Sims, R., van der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 31 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S-H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Lupton, M. K., Proitsi, P., Hodges, A., Patel, Y., Al-Chalabi, A., Shaw, C. E., Powell, J. & ARUK Consortium, 1 Sep 2017, In: Nature Genetics. 49, p. 1373-1384

    Research output: Contribution to journalArticlepeer-review

  12. No Genetic Overlap between Circulating Iron Levels and Alzheimer's Disease

    Lupton, M. K., Benyamin, B., Proitsi, P., Nyholt, D. R., Ferreira, M. A., Montgomery, G. W., Heath, A. C., Madden, P. A., Medland, S. E., Gordon, S. D., Lovestone, S., Tsolaki, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Powell, J. F., Bush, A. I., Wright, M. J., Martin, N. G. & 1 others, Whitfield, J. B., 3 Jul 2017, In: JOURNAL OF ALZHEIMERS DISEASE. 59, 1, p. 85-99 15 p.

    Research output: Contribution to journalArticlepeer-review

  13. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Proitsi, P., Kim, M., Whiley, L., Simmons, A., Sattlecker, M., Velayudhan, L., Lupton, M. K., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C., 28 Sep 2016, In: Alzheimer's & Dementia. 13, 2, p. 140-151 12 p.

    Research output: Contribution to journalArticlepeer-review

  14. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

    Fogh, I., Lin, K., Tiloca, C., Rooney, J., Gellera, C., Diekstra, F. P., Ratti, A., Shatunov, A., Van Es, M. A., Proitsi, P., Jones, A., Sproviero, W., Chiò, A., McLaughlin, R. L., Sorarù, G., Corrado, L., Stahl, D., Del Bo, R., Cereda, C., Castellotti, B. & 29 others, Glass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J., 1 Jul 2016, In: JAMA Neurology. 73, 7, p. 812-820 9 p.

    Research output: Contribution to journalArticlepeer-review

  15. Shared genetic contribution to ischemic stroke and Alzheimer's disease: Ischemic Stroke and Alzheimer's Disease

    Traylor, M., Adib-samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., METASTROKE and International Genomics of Alzheimer's Project (IGAP) investigators, Lovestone, S. H. & Proitsi, P., 1 May 2016, In: Annals of Neurology. 79, 5, p. 739-747

    Research output: Contribution to journalArticlepeer-review

  16. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume

    Lupton, M. K., Strike, L., Hansell, N. K., Wen, W., Mather, K. A., Armstrong, N. J., Thalamuthu, A., McMahon, K. L., de Zubicaray, G. I., Assareh, A. A., Simmons, A., Proitsi, P., Powell, J. F., Montgomery, G. W., Hibar, D. P., Westman, E., Tsolaki, M., Kloszewska, I., Soininen, H., Mecocci, P. & 9 others, Velas, B., Lovestone, S., Brodaty, H., Ames, D., Trollor, J. N., Martin, N. G., Thompson, P. M., Sachdev, P. S. & Wright, M. J., 1 Apr 2016, In: Neurobiology of Aging. 40, p. 68-77 10 p.

    Research output: Contribution to journalArticlepeer-review

  17. A novel Alzheimer disease locus located near the gene encoding tau protein

    Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J-C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L-S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 31 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S-H., Boland, A., Becker, T., Kukull, W. A., van der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Powell, J. F., IGAP Consortium & Proitsi, P., Jan 2016, In: Molecular Psychiatry. 21, 1, p. 108-17 10 p.

    Research output: Contribution to journalArticlepeer-review

  18. Lipidomics comparing DCD and DBD liver allografts uncovers lysophospholipids elevated in recipients undergoing early allograft dysfunction

    Xu, J., Casas-Ferreira, A. M., Ma, Y., Sen, A., Kim, M., Proitsi, P., Shkodra, M., Tena, M., Srinivasan, P., Heaton, N., Jassem, W. & Legido-Quigley, C., 4 Dec 2015, In: Scientific Reports. 5, 10 p., 17737.

    Research output: Contribution to journalArticlepeer-review

  19. Common polygenic variation enhances risk prediction for Alzheimer's disease

    Escott-Price, V., Sims, R., Bannister, C., Harold, D., Vronskaya, M., Majounie, E., Badarinarayan, N., GERAD/PERADES, Proitsi, P., IGAP consortia, Morgan, K., Passmore, P., Holmes, C., Powell, J., Brayne, C., Gill, M., Mead, S., Goate, A., Cruchaga, C., Lambert, J-C. & 10 others, van Duijn, C., Maier, W., Ramirez, A., Holmans, P., Jones, L., Hardy, J., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., 1 Dec 2015, In: Brain. 138, 12, p. 3673-3684 12 p.

    Research output: Contribution to journalArticlepeer-review

  20. No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease

    Chiam, J. T. W., Lunnon, K., Voyle, N., Proitsi, P., Coppola, G., Geschwind, D., Nelson, S., Johnston, C., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Hodges, A., Lovestone, S., Newhouse, S., Dobson, R. J. B., Kiddle, S. J. & Sattlecker, M., 3 Aug 2015, In: JOURNAL OF ALZHEIMERS DISEASE. 47, 3, p. 741-750 10 p.

    Research output: Contribution to journalArticlepeer-review

  21. Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

    Østergaard, S. D., Mukherjee, S., Sharp, S. J., Proitsi, P., Lotta, L. A., Day, F., Perry, J. R. B., Boehme, K. L., Walter, S., Kauwe, J. S., Gibbons, L. E., Larson, E. B., Powell, J. F., Langenberg, C., Crane, P. K., Wareham, N. J. & Scott, R. A., 1 Jun 2015, In: PL o S Medicine. 12, 6, e1001841.

    Research output: Contribution to journalArticlepeer-review

  22. Convergent genetic and expression data implicate immunity in Alzheimer's disease

    International Genomics of Alzheimer's Disease Consortium (IGAP)†, , Jun 2015, In: Alzheimer's & Dementia. 11, 6, p. 658-671

    Research output: Contribution to journalArticlepeer-review

  23. Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease

    Proitsi, P., Kim, M., Whiley, L., Pritchard, M., Leung, R., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Sham, P., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C., 13 Jan 2015, In: Translational psychiatry. 5, 8 p., e494.

    Research output: Contribution to journalArticlepeer-review

  24. Pattern of smell identification impairment in alzheimer's disease

    Velayudhan, L., Gasper, A., Pritchard, M., Baillon, S., Messer, C. & Proitsi, P., 2015, In: JOURNAL OF ALZHEIMERS DISEASE. 46, 2, p. 381-387 7 p.

    Research output: Contribution to journalArticlepeer-review

  25. Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

    Proitsi, P., Lupton, M. K., Velayudhan, L., Hunter, G., Newhouse, S., Lin, K., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Craig, D., Todd, S., Johnston, J. A., McGuinness, B., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Passmore, P. A., Sims, R. & 7 others, Williams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S., Powell, J. F. & Alzheimer's Disease Neuroimaging Initiative, Dec 2014, In: Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p., 2883.

    Research output: Contribution to journalArticlepeer-review

  26. Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

    Proitsi, P., Lupton, M. K., Velayudhan, L., Newhouse, S., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Williams, J., Harold, D., Sims, R., Gerrish, A., Chapman, J., Escott-Price, V., Abraham, R., Hollingworth, P. & 74 others, Hamshere, M., Singh Pahwa, J., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A., Williams, K., Lovestone, S., Powell, J. F., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K., Passmore, P., Craig, D., Mcguinness, B., Johnston, J. A., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Guerreiro, R., Singleton, A., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., Mcquillin, A., Gwilliam, R., Deloukas, P., Nöthen, M. M., Holmans, P., O'donovan, M., Owen, M. J., Williams, J., Stewart, R. & Sham, P., 16 Sep 2014, In: PLoS Medicine. 11, 9

    Research output: Contribution to journalArticlepeer-review

  27. Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis

    Proitsi, P., Lupton, M. K., Velayudhan, L., Newhouse, S., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Williams, J., Stewart, R., Sham, P., Lovestone, S., Powell, J. F. & Alzheimer's Disease Neuroimaging Initiative, Sep 2014, In: PL o S Medicine. 11, 9, p. e1001713 15 p.

    Research output: Contribution to journalArticlepeer-review

  28. Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

    Condliffe, D., Wong, A., Troakes, C., Proitsi, P., Patel, Y., Chouliaras, L., Fernandes, C., Cooper, J., Lovestone, S., Schalkwyk, L., Mill, J. & Lunnon, K., Aug 2014, In: Neurobiology of Aging. 35, 8, p. 1850-1854 5 p.

    Research output: Contribution to journalArticlepeer-review

  29. Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease

    Escott-Price, V., Bellenguez, C., Wang, L-S., Choi, S-H., Harold, D., Jones, L., Holmans, P., Gerrish, A., Vedernikov, A., Richards, A., DeStefano, A. L., Lambert, J-C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Jun, G., Bis, J. C., Beecham, G. W., Grenier-Boley, B., Russo, G. & 31 others, Thornton-Wells, T. A., Denning, N., Smith, A. V., Chouraki, V., Thomas, C., Ikram, M. A., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C-F., Schmidt, H., Kunkle, B., Dunstan, M. L., Vronskaya, M., Johnson, A. D., Ruiz, A., Bihoreau, M-T., Reitz, C., Pasquier, F., Hollingworth, P., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Lovestone, S., Proitsi, P., Powell, J. F. & United Kingdom Brain Expression, 12 Jun 2014, In: PL o S One . 9, 6, 13 p., e94661.

    Research output: Contribution to journalArticlepeer-review

  30. Genetic modulation of the response bias towards facial displays of anger and happiness

    Gohier, B., Senior, C., Radua, J., El-Hage, W., Reichenberg, A., Proitsi, P., Phillips, M. L. & Surguladze, S. A., May 2014, In: European Psychiatry. 29, 4, p. 197-202 6 p.

    Research output: Contribution to journalArticlepeer-review

  31. Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology

    Sattlecker, M., Kiddle, S. J., Newhouse, S., Proitsi, P., Nelson, S., Williams, S., Johnston, C., Killick, R., Simmons, A., Westman, E., Hodges, A., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., the AddNeuroMed Consortium & Dobson, R. J. B., 28 Apr 2014, In: Alzheimer's & Dementia. 10, 6, p. 724-734 11 p.

    Research output: Contribution to journalArticlepeer-review

  32. Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

    Proitsi, P., Lee, S. H., Lunnon, K., Keohane, A., Powell, J., Troakes, C., Al-Sarraj, S., Furney, S., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Hodges, A. & AddNeuroMed Consortium, Feb 2014, In: Neurobiology of Aging. 35, 2, p. 279-290 12 p.

    Research output: Contribution to journalArticlepeer-review

  33. Blood-based biomarker discovery using aptamer capture (SOMAscan) platform technology

    Sattlecker, M., Pritchard, M., Proitsi, P., Kiddle, S., Newhouse, S., Simmons, A., Johnston, C., Leung, R., Dixit, A., Bazenet, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Stewart, A., Williams, S. C. R., Nelson, S., Lovestone, S. H. & Dobson, R. J. B., 1 Jul 2013, In: Alzheimer's Dementia: The Journal of the Alzheimer's Association. 9, 4, p. P861 1 p.

    Research output: Contribution to journalArticlepeer-review

  34. Inflammatory Proteins in Plasma Are Associated with Severity of Alzheimer's Disease

    Leung, R., Proitsi, P., Simmons, A., Lunnon, K., Guentert, A., Kronenberg, D., Pritchard, M., Tsolaki, M., Mecocci, P., Kloszewska, I., Vellas, B., Soininen, H., Wahlund, L-O. & Lovestone, S., 10 Jun 2013, In: PL o S One . 8, 6, 10 p., e64971.

    Research output: Contribution to journalArticlepeer-review

  35. The deletion variant of α2b-adrenergic receptor is associated with decreased risk in Alzheimer's disease and mild cognitive impairment

    Koutroumani, M., Daniilidou, M., Giannakouros, T., Proitsi, P., Liapi, D., Germanou, A., Nikolakaki, E. & Tsolaki, M., 1 May 2013, In: Journal of the Neurological Sciences. 328, 1-2, p. 19-23 5 p.

    Research output: Contribution to journalArticlepeer-review

  36. Candidate blood proteome markers of Alzheimer's disease onset and progression: A systematic review and replication study

    Bazenet, C., Kiddle, S., Sattlecker, M., Proitsi, P., Simmons, A., Westman, E., Nelson, S., Sterling, D., Williams, S., Hodges, A., Johnston, C., Dobson, R., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Newhouse, S., Dobson, R. J. B. & Lovestone, S. H., 2013, In: Alzheimer's Dementia: The Journal of the Alzheimer's Association. 9, 4, p. P857-P858 P4-344.

    Research output: Contribution to journalPoster abstractpeer-review

  37. Identification of cis-regulatory variation influencing protein abundance levels in human plasma

    Lourdusamy, A., Newhouse, S., Lunnon, K., Proitsi, P., Powell, J., Hodges, A., Nelson, S. K., Stewart, A., Williams, S., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Lovestone, S., Dobson, R. & Consortium, A., 15 Aug 2012, In: Human Molecular Genetics. 21, 16, p. 3719-3726 8 p.

    Research output: Contribution to journalArticlepeer-review

  38. Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

    Proitsi, P., Lupton, M. K., Dudbridge, F., Tsolaki, M., Hamilton, G., Daniilidou, M., Pritchard, M., Lord, K., Martin, B. M., Craig, D., Todd, S., McGuinness, B., Hollingworth, P., Harold, D., Kloszewska, I., Soininen, H., Mecocci, P., Velas, B., Gill, M., Lawlor, B. & 6 others, Rubinsztein, D. C., Brayne, C., Passmore, P. A., Williams, J., Lovestone, S. & Powell, J. F., Aug 2012, In: Neurobiology of Aging. 33, 8, p. 1843.e9-1843.e17 9 p., 1843.

    Research output: Contribution to journalArticlepeer-review

  39. Genetic variants influencing human aging from late-onset Alzheimertextquotesingles disease (LOAD) genome-wide association studies (GWAS)

    Shi, H., Belbin, O., Medway, C., Brown, K., Kalsheker, N., Carrasquillo, M., Proitsi, P., Powell, J., Lovestone, S., Goate, A., Younkin, S., Passmore, P. & Morgan, K., Aug 2012, In: Neurobiology of Aging. 33, 8, p. 1849.e5-1849.e18 14 p., 1849.

    Research output: Contribution to journalArticlepeer-review

  40. Complement activation as a biomarker for Alzheimer's disease

    Aiyaz, M., Lupton, M. K., Proitsi, P., Powell, J. F. & Lovestone, S., Feb 2012, In: Immunobiology. 217, 2, p. 204 - 215 12 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  41. Interaction of catechol O-methyltransferase and serotonin transporter genes modulates effective connectivity in a facial emotion-processing circuitry

    Surguladze, S. A., Radua, J., El-Hage, W., Gohier, B., Sato, J. R., Kronhaus, D. M., Proitsi, P., Powell, J. & Phillips, M. L., Jan 2012, In: Translational psychiatry. 2, p. - 8 p., e70.

    Research output: Contribution to journalArticlepeer-review

  42. Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood

    Lunnon, K., Ibrahim, Z., Proitsi, P., Lourdusamy, A., Newhouse, S., Sattlecker, M., Furney, S., Saleem, M., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Coppola, G., Geschwind, D., Simmons, A., Lovestone, S., Dobson, R., Hodges, A. & AddNeuroMed Consortium, 2012, In: JOURNAL OF ALZHEIMERS DISEASE. 30, 3, p. 685-710 26 p.

    Research output: Contribution to journalArticlepeer-review

  43. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

    Gerrish, A., Russo, G., Richards, A., Moskvina, V., Ivanov, D., Harold, D., Sims, R., Abraham, R., Hollingworth, P., Chapman, J., Hamshere, M., Pahwa, J. S., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J. & 73 others, Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Johnston, J. A., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Kölsch, H., Heun, R., Schürmann, B., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Davies, G., Harris, S. E., Starr, J. M., Deary, I. J., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K-H., Klopp, N., Wichmann, H-E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Jones, L., Holmans, P. A., O'Donovan, M. C., Owen, M. J. & Williams, J., 2012, In: JOURNAL OF ALZHEIMERS DISEASE. 28, 2, p. 377-387 11 p.

    Research output: Contribution to journalArticlepeer-review

  44. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease

    Furney, S. J., Simmons, A., Breen, G., Pedroso, I., Lunnon, K., Proitsi, P., Hodges, A., Powell, J., Wahlund, L-O., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Spenger, C., Lathrop, M., Shen, L., Kim, S., Saykin, A. J., Weiner, M. W. & 2 others, Lovestone, S. & AddNeuroMed Consortium, Alzheimer's Dis Neuroimaging, Nov 2011, In: Molecular Psychiatry. 16, 11, p. 1130-1138 9 p.

    Research output: Contribution to journalArticlepeer-review

  45. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

    Hollingworth, P., Harold, D., Sims, R., Gerrish, A., Lambert, J-C., Carrasquillo, M. M., Abraham, R., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Jones, N., Stretton, A., Thomas, C., Richards, A., Ivanov, D., Widdowson, C., Chapman, J., Lovestone, S., Powell, J. & 152 others, Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Beaumont, H., Warden, D., Wilcock, G., Love, S., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Hardy, J., Mead, S., Fox, N. C., Rossor, M., Collinge, J., Maier, W., Jessen, F., Ruether, E., Schuermann, B., Heun, R., Koelsch, H., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Froelich, L., Hampel, H., Gallacher, J., Huell, M., Rujescu, D., Giegling, I., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Muehleisen, T. W., Noethen, M. M., Moebus, S., Joeckel, K-H., Klopp, N., Wichmann, H-E., Pankratz, V. S., Sando, S. B., Aasly, J. O., Barcikowska, M., Wszolek, Z. K., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., van Duijn, C. M., Breteler, M. M. B., Ikram, M. A., DeStefano, A. L., Fitzpatrick, A. L., Lopez, O., Launer, L. J., Seshadri, S., Berr, C., Campion, D., Epelbaum, J., Dartigues, J-F., Tzourio, C., Alperovitch, A., Lathrop, M., Feulner, T. M., Friedrich, P., Riehle, C., Krawczak, M., Schreiber, S., Mayhaus, M., Nicolhaus, S., Wagenpfeil, S., Steinberg, S., Stefansson, H., Stefansson, K., Snaedal, J., Bjornsson, S., Jonsson, P. V., Chouraki, V., Genier-Boley, B., Hiltunen, M., Soininen, H., Combarros, O., Zelenika, D., Delepine, M., Bullido, M. J., Pasquier, F., Mateo, I., Frank-Garcia, A., Porcellini, E., Hanon, O., Coto, E., Alvarez, V., Bosco, P., Siciliano, G., Mancuso, M., Panza, F., Solfrizzi, V., Nacmias, B., Sorbi, S., Bossu, P., Piccardi, P., Arosio, B., Annoni, G., Seripa, D., Pilotto, A., Scarpini, E., Galimberti, D., Brice, A., Hannequin, D., Licastro, F., Jones, L., Holmans, P. A., Jonsson, T., Riemenschneider, M., Morgan, K., Younkin, S. G., Owen, M. J., O'Donovan, M., Amouyel, P. & Williams, J., May 2011, In: Nature Genetics. 43, 5, p. 429-435 7 p.

    Research output: Contribution to journalArticlepeer-review

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