King's College London

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Miss Petroula Proitsi

  1. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Proitsi, P., Kim, M., Whiley, L., Simmons, A., Sattlecker, M., Velayudhan, L., Lupton, M. K., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C. Feb 2017 In : Alzheimer's & Dementia. 13, 2, p. 140-151 12 p.

    Research output: Contribution to journalArticle

  2. No Genetic Overlap between Circulating Iron Levels and Alzheimer's Disease

    Lupton, M. K. , Benyamin, B. , Proitsi, P. , Nyholt, D. R. , Ferreira, M. A. , Montgomery, G. W. , Heath, A. C. , Madden, P. A. , Medland, S. E. , Gordon, S. D. , Lovestone, S. , Tsolaki, M. , Kloszewska, I. , Soininen, H. , Mecocci, P. , Vellas, B. , Powell, J. F. , Bush, A. I. , Wright, M. J. , Martin, N. G. & 1 others Whitfield, J. B. 2017 In : JOURNAL OF ALZHEIMERS DISEASE. 59, 1, p. 85-99 15 p.

    Research output: Contribution to journalArticle

  3. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume

    Lupton, M. K. , Strike, L. , Hansell, N. K. , Wen, W. , Mather, K. A. , Armstrong, N. J. , Thalamuthu, A. , McMahon, K. L. , de Zubicaray, G. I. , Assareh, A. A. , Simmons, A. , Proitsi, P. , Powell, J. F. , Montgomery, G. W. , Hibar, D. P. , Westman, E. , Tsolaki, M. , Kloszewska, I. , Soininen, H. , Mecocci, P. & 9 others Velas, B., Lovestone, S., Brodaty, H., Ames, D., Trollor, J. N., Martin, N. G., Thompson, P. M., Sachdev, P. S. & Wright, M. J. 1 Apr 2016 In : Neurobiology of Aging. 40, p. 68-77 10 p.

    Research output: Contribution to journalArticle

  4. Lipidomics comparing DCD and DBD liver allografts uncovers lysophospholipids elevated in recipients undergoing early allograft dysfunction

    Xu, J., Casas-Ferreira, A. M., Ma, Y., Sen, A., Kim, M., Proitsi, P., Shkodra, M., Tena, M., Srinivasan, P., Heaton, N., Jassem, W. & Legido-Quigley, C. 4 Dec 2015 In : Scientific Reports. 5, 10 p., 17737

    Research output: Contribution to journalArticle

  5. No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease

    Chiam, J. T. W., Lunnon, K., Voyle, N., Proitsi, P., Coppola, G., Geschwind, D., Nelson, S., Johnston, C., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolakik, M., Vellas, B., Hodges, A., Lovestone, S., Newhouse, S., Dobson, R. J. B., Kiddle, S. J. & Sattlecker, M. 3 Aug 2015 In : JOURNAL OF ALZHEIMERS DISEASE. 47, 3, p. 741-750 10 p.

    Research output: Contribution to journalArticle

  6. Pattern of smell identification impairment in alzheimer's disease

    Velayudhan, L., Gasper, A., Pritchard, M., Baillon, S., Messer, C. & Proitsi, P. 30 May 2015 In : JOURNAL OF ALZHEIMERS DISEASE. 46, 2, p. 381-387 7 p.

    Research output: Contribution to journalArticle

  7. Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease

    Proitsi, P., Kim, M., Whiley, L., Pritchard, M., Leung, R., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Sham, P., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C. 13 Jan 2015 In : Translational psychiatry. 5, 8 p., e494

    Research output: Contribution to journalArticle

  8. Genetic influences on metabolite levels in Alzheimer’s disease

    Proitsi, P., Min, K., Whiley, L., Newhouse, S., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M. & Vellas, B. 2015 In : Alzheimer's Dementia: The Journal of the Alzheimer's Association. 11, 7, p. P279-P280

    Research output: Contribution to journalArticle

  9. Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

    Proitsi, P. , Lupton, M. K. , Velayudhan, L. , Hunter, G. , Newhouse, S. , Lin, K. , Fogh, I. , Tsolaki, M. , Daniilidou, M. , Pritchard, M. , Craig, D. , Todd, S. , Johnston, J. A. , McGuinness, B. , Kloszewska, I. , Soininen, H. , Mecocci, P. , Vellas, B. , Passmore, P. A. , Sims, R. & 7 others Williams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S., Powell, J. F. & Alzheimer's Disease Neuroimaging Initiative Dec 2014 In : Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p., 2883

    Research output: Contribution to journalArticle

  10. Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology

    Sattlecker, M., Kiddle, S. J., Newhouse, S., Proitsi, P., Nelson, S., Williams, S., Johnston, C., Killick, R., Simmons, A., Westman, E., Hodges, A., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., the AddNeuroMed Consortium & Dobson, R. J. B. Nov 2014 In : Alzheimer's & Dementia. 10, 6, p. 724-734 11 p.

    Research output: Contribution to journalArticle

  11. Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis

    Proitsi, P., Lupton, M. K., Velayudhan, L., Newhouse, S., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Williams, J., Stewart, R., Sham, P., Lovestone, S., Powell, J. F. & Alzheimer's Disease Neuroimaging Initiative Sep 2014 In : PL o S Medicine. 11, 9, p. e1001713 15 p.

    Research output: Contribution to journalArticle

  12. Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

    Condliffe, D., Wong, A., Troakes, C., Proitsi, P., Patel, Y., Chouliaras, L., Fernandes, C., Cooper, J., Lovestone, S., Schalkwyk, L., Mill, J. & Lunnon, K. Aug 2014 In : Neurobiology of Aging. 35, 8, p. 1850-1854 5 p.

    Research output: Contribution to journalArticle

  13. Genetic modulation of the response bias towards facial displays of anger and happiness

    Gohier, B., Senior, C., Radua, J., El-Hage, W., Reichenberg, A., Proitsi, P., Phillips, M. L. & Surguladze, S. A. May 2014 In : European Psychiatry. 29, 4, p. 197-202 6 p.

    Research output: Contribution to journalArticle

  14. Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

    Proitsi, P., Lee, S. H., Lunnon, K., Keohane, A., Powell, J., Troakes, C., Al-Sarraj, S., Furney, S., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Hodges, A. & AddNeuroMed Consortium Feb 2014 In : Neurobiology of Aging. 35, 2, p. 279-290 12 p.

    Research output: Contribution to journalArticle

  15. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

    Whiley, L., Sen, A., Heaton, J., Proitsi, P., Garcia-Gomez, D., Leung, R., Smith, N., Thambisetty, M., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Lovestone, S. & Legido Quigley, C. Feb 2014 In : Neurobiology of Aging. 35, 2, p. 271-278 8 p.

    Research output: Contribution to journalArticle

  16. Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study

    Kiddle, S. J., Sattlecker, M., Proitsi, P., Simmons, A., Westman, E., Bazenet, C., Nelson, S. K., Williams, S., Hodges, A., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Newhouse, S., Lovestone, S. & Dobson, R. J. B. 2014 In : JOURNAL OF ALZHEIMERS DISEASE. 38, 3, p. 515-531 17 p., N/A

    Research output: Contribution to journalLiterature review

  17. Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study

    Kiddle, S. J., Sattlecker, M., Proitsi, P., Simmons, A., Westman, E., Bazenet, C., Nelson, S. K., Williams, S., Hodges, A. & Johnston, C. 2014 In : Journal of Alzheimer's Disease. 38, 3, p. 515-531 17 p.

    Research output: Contribution to journalArticle

  18. The role of ABCA1 gene sequence variants on risk of Alzheimer's disease

    Lupton, M. K., Proitsi, P., Lin, K., Hamilton, G., Daniilidou, M., Tsolaki, M. & Powell, J. F. 2014 In : Journal of Alzheimer's disease : JAD. 38, 4, p. 897-906 10 p.

    Research output: Contribution to journalArticle

  19. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Lambert, J-C. , Ibrahim-Verbaas, C. A. , Harold, D. , Naj, A. C. , Sims, R. , Bellenguez, C. , Jun, G. , DeStefano, A. L. , Bis, J. C. , Beecham, G. W. , Grenier-Boley, B. , Russo, G. , Thornton-Wells, T. A. , Jones, N. , Smith, A. V. , Chouraki, V. , Thomas, C. , Ikram, M. A. , Zelenika, D. , Vardarajan, B. N. & 166 others Kamatani, Y., Lin, C-F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M-T., Choi, S-H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Moron, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fievet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossu, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez-Garcia, F., Fox, N. C., Hardy, J., Naranjo, M. C. D., Bosco, P., Clarke, R., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., de Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Wang, L-S., Dartigues, J-F., Mayeux, R., Tzourio, C., Hofman, A., Noethen, M. M., Graff, C., Psaty, B. M., Jones, L., Haines, J. L., Holmans, P. A., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farrer, L. A., van Duijn, C. M., Van Broeckhoven, C., Moskvina, V., Seshadri, S., Williams, J., Schellenberg, G. D., Amouyel, P., EADI, GERAD, ADGC & CHARGE Dec 2013 In : Nature Genetics. 45, 12, p. 1452-1458 7 p., N/A

    Research output: Contribution to journalArticle

  20. Blood-based biomarker discovery using aptamer capture (SOMAscan) platform technology

    Sattlecker, M., Pritchard, M., Proitsi, P., Kiddle, S., Newhouse, S., Simmons, A., Johnston, C., Leung, R., Dixit, A., Bazenet, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Stewart, A., Williams, S. C. R., Nelson, S., Lovestone, S. H. & Dobson, R. J. B. 1 Jul 2013 In : Alzheimer's Dementia: The Journal of the Alzheimer's Association. 9, 4, p. P861 1 p.

    Research output: Contribution to journalArticle

  21. Inflammatory Proteins in Plasma Are Associated with Severity of Alzheimer's Disease

    Leung, R., Proitsi, P., Simmons, A., Lunnon, K., Guentert, A., Kronenberg, D., Pritchard, M., Tsolaki, M., Mecocci, P., Kloszewska, I., Vellas, B., Soininen, H., Wahlund, L-O. & Lovestone, S. 10 Jun 2013 In : PL o S One . 8, 6, p. N/A 10 p., e64971

    Research output: Contribution to journalArticle

  22. A Blood Gene Expression Marker of Early Alzheimer's Disease

    Lunnon, K., Sattlecker, M., Furney, S. J., Coppola, G., Simmons, A., Proitsi, P., Lupton, M. K., Lourdusamy, A., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Geschwind, D., Lovestone, S., Dobson, R., Hodges, A. & AddNeuroMed Consortium 2013 In : JOURNAL OF ALZHEIMERS DISEASE. 33, 3, p. 737-753 17 p.

    Research output: Contribution to journalArticle

  23. Candidate Blood Proteome Markers of Alzheimer’s Disease Onset and Progression: A Systematic Review and Replication Study

    Kiddle, S., Sattlecker, M., Proitsi, P., Simmons, A., Westman, E., Bazenet, C., Nelson, S., Williams, S., Hodges, A., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Newhouse, S., Lovestone, S. & Dobson, R. 2013 In : JOURNAL OF ALZHEIMERS DISEASE. N/A, N/A, p. N/A N/A

    Research output: Contribution to journalArticle

  24. Entorhinal Cortex Thickness Predicts Cognitive Decline in Alzheimer's Disease

    Velayudhan, L., Proitsi, P., Westman, E., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Spenger, C., Hodges, A., Powell, J., Lovestone, S., Simmons, A. & AddNeuroMed Consortium 2013 In : JOURNAL OF ALZHEIMERS DISEASE. 33, 3, p. 755-766 12 p.

    Research output: Contribution to journalArticle

  25. Missense substitutions associated with behavioural disturbances in Alzheimer's disease (AD)

    Proitsi, P. & Powell, J. F. 1 Aug 2012 In : Brain Research Bulletin. 88, 5, p. 394-405 12 p.

    Research output: Contribution to journalArticle

  26. Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

    Proitsi, P. , Lupton, M. K. , Dudbridge, F. , Tsolaki, M. , Hamilton, G. , Daniilidou, M. , Pritchard, M. , Lord, K. , Martin, B. M. , Craig, D. , Todd, S. , McGuinness, B. , Hollingworth, P. , Harold, D. , Kloszewska, I. , Soininen, H. , Mecocci, P. , Velas, B. , Gill, M. , Lawlor, B. & 6 others Rubinsztein, D. C., Brayne, C., Passmore, P. A., Williams, J., Lovestone, S. & Powell, J. Aug 2012 In : Neurobiology of Aging. 33, 8, p. 1843.e9-1843.e17 9 p., 1843

    Research output: Contribution to journalArticle

  27. Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS)

    Shi, H., Belbin, O., Medway, C., Brown, K., Kalsheker, N., Carrasquillo, M., Proitsi, P., Powell, J., Lovestone, S., Goate, A., Younkin, S., Passmore, P., Morgan, K., Genetic Environm Risk Alzheimer's & Alzheimer's Res UK ARUK Consortium Aug 2012 In : Neurobiology of Aging. 33, 8, p. 1849.e5-1849.e18 14 p., 1849

    Research output: Contribution to journalArticle

  28. A blood gene expression biomarker of early Alzheimer's disease

    Hodges, A., Lunnon, K., Furney, S., Proitsi, P., Sattlecker, M., Dobson, R., Lourdusamy, A., Simmons, A., Coppola, G., Lupton, M. & Soininen, H. Jul 2011 In : Alzheimer's & Dementia. 7, 4, Supplement, p. e13-e14 2 p.

    Research output: Contribution to journalArticle

  29. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

    Thambisetty, M. , Simmons, A. , Velayudhan, L. , Hye, A. , Campbell, J. , Zhang, Y. , Wahlund, L-O. , Westman, E. , Kinsey, A. , Güntert, A. , Proitsi, P. , Powell, J. , Causevic, M. , Killick, R. , Lunnon, K. , Lynham, S. , Broadstock, M. , Choudhry, F. , Howlett, D. R. , Williams, R. J. & 27 others Sharp, S. I., Mitchelmore, C., Tunnard, C., Leung, R., Foy, C., O'Brien, D., Breen, G., Furney, S. J., Ward, M., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Hodges, A., Murphy, D. G. M., Parkins, S., Richardson, J. C., Resnick, S. M., Ferrucci, L., Wong, D. F., Zhou, Y., Muehlboeck, S., Evans, A., Francis, P. T., Spenger, C. & Lovestone, S. Jul 2010 In : Archives of General Psychiatry. 67, 7, p. 739-48 10 p.

    Research output: Contribution to journalArticle

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