Philip Eaton

Finished

BHF Research Excellence Award

Shah, A. (Primary Investigator), Botnar, R. (Co-Investigator), Chowienczyk, P. (Co-Investigator), Eaton, P. (Co-Investigator), Garcia-Manyes, S. (Co-Investigator), Gautel, M. (Co-Investigator), Giacca, M. (Co-Investigator), Irving, M. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), Otsu, K. (Co-Investigator), Ourselin, S. (Co-Investigator), Parsons, M. (Co-Investigator), Razavi, R. (Co-Investigator), Schnabel, J. (Co-Investigator), Shanahan, C. (Co-Investigator), Xu, Q. (Co-Investigator) & Phinikaridou, A. (Co-Investigator)

BHF British Heart Foundation

1/04/2019 → 31/03/2024

Project: Research

Thiol-disulfide redox switches in protein kinases and their role in cardiovascular health and disease

Eaton, P. (Primary Investigator), Francois, A. (Co-Investigator) & Prysyazhna, O. (Co-Investigator)

MRC Medical Research Council

1/05/2018 → 30/04/2023

Project: Research

Furthering our understanding of PKGIα in cardiovascular health and disease

Eaton, P. (Primary Investigator), Prysyazhna, O. (Co-Investigator), Cho, H. (Co-Investigator) & Francois, A. (Co-Investigator)

BHF British Heart Foundation

1/03/2018 → 28/02/2023

Project: Research

An investigation of the potential therapeutic effects of Sulforadex in Noonan syndrome

Eaton, P. (Primary Investigator) & Cho, H. (Co-Investigator)

BHF British Heart Foundation

1/09/2017 → 31/08/2020

Project: Research

PKG-activating drugs as a novel therapy for hypertension

Eaton, P. (Primary Investigator) & Cho, H. (Co-Investigator)

1/07/2017 → 30/09/2018

Project: Research

Activation of soluble Epoxide Hydrolase by intra-protein disulfide formation - role in regulating cardiovascular function in health and disease

Charles, B. (Primary Investigator) & Eaton, P. (Co-Investigator)

BHF British Heart Foundation

1/07/2017 → 30/06/2022

Project: Research

Furthering our understanding of the redox regulation of Protein Kinase A in the cardiovascular system

Eaton, P. (Primary Investigator) & Prysyazhna, O. (Co-Investigator)

MRC Medical Research Council

1/07/2017 → 30/09/2020

Project: Research

Biological consequences of S-Nitrosylation

Eaton, P. (Primary Investigator) & Switzer, C. (Co-Investigator)

7/01/2017 → 30/06/2020

Project: Research

MICA: Identification of novel Sulforaphane molecular targets in human basal-like breast cancer

Eaton, P. (Primary Investigator) & Switzer, C. (Co-Investigator)

1/01/2017 → 31/12/2020

Project: Research

King’s NMR Facility for structural biology, metabolic profiling and drug discovery

Conte, M. (Primary Investigator), Avkiran, M. (Co-Investigator), Blower, P. (Co-Investigator), Dodding, M. (Co-Investigator), Eaton, P. (Co-Investigator), Gautel, M. (Co-Investigator), Irving, M. (Co-Investigator), Malim, M. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Otsu, K. (Co-Investigator), Pastore, A. (Co-Investigator), Pfuhl, M. (Co-Investigator), Poston, L. (Co-Investigator), Shah, A. (Co-Investigator), Shanahan, C. (Co-Investigator), Shattock, M. (Co-Investigator) & Williamson, C. (Co-Investigator)

BHF British Heart Foundation, Wellcome Trust

1/01/2017 → 31/12/2021

Project: Research

Validation of a New Prognostic Marker that Predicts Survival in Severe Sepsis

Mayr, M. (Primary Investigator), Eaton, P. (Co-Investigator) & academic, A. (Co-Investigator)

1/12/2016 → 30/11/2018

Project: Research

An investigation into a novel redox-dependent regulation of RSK-mediated growth

Eaton, P. (Primary Investigator) & Prysyazhna, O. (Co-Investigator)

1/09/2016 → 31/08/2019

Project: Research

Identification and exploitation of novel Sulforaphane molecular targets in human basal-like breast cancer

Eaton, P. (Primary Investigator) & Switzer, C. (Co-Investigator)

1/07/2016 → 30/06/2019

Project: Research

Role of neuronal nitric oxide synthase (nNOS) in the pathophysiology of human heart failure with preserved ejection fraction (HFPEF)

Shah, A. (Primary Investigator), Botnar, R. (Co-Investigator), Chiribiri, A. (Co-Investigator), Chowienczyk, P. (Co-Investigator) & Eaton, P. (Co-Investigator)

4/04/2016 → 3/04/2021

Project: Research

Role of neuronal nitric oxide synthase (nNOS) in the pathophysiology of human heart failure

Shah, A. (Primary Investigator), Botnar, R. (Co-Investigator), Chowienczyk, P. (Co-Investigator) & Eaton, P. (Co-Investigator)

4/04/2016 → 3/04/2021

Project: Research

An investigation into the redox-mediated regulation of RSK and its potential role in cardiac hypertrophy and remodelling

Eaton, P. (Primary Investigator)

1/06/2015 → 31/05/2018

Project: Research

Expanding our understanding of the redox regulation of soluble Epoxide Hydrolase in cardiovascular health and disease

Eaton, P. (Primary Investigator)

BHF British Heart Foundation

1/06/2015 → 31/05/2018

Project: Research

Surviving myocardial ischemia. A new role for the mitochondrial pyruvate carrier?

Eaton, P. (Primary Investigator)

1/01/2015 → 31/12/2018

Project: Research

Does redox state of PKG1alpha control hypoxic vasoconstriction and remodelling in the pulmonary vasculature?

Rudyk, O. (Primary Investigator) & Eaton, P. (Co-Investigator)

BHF British Heart Foundation

1/01/2015 → 31/03/2020

Project: Research

An investigation to the redox regulation of RSK and its potential role in cardiac hypertrophy and remodelling

Eaton, P. (Primary Investigator)

1/07/2014 → 30/06/2018

Project: Research

Surviving myocardial ischemia- a role for the mitochondria pyruvate carrie - cardioMPC

Eaton, P. (Primary Investigator)

1/04/2014 → 31/03/2016

Project: Research

Disulfide activated protein kinase G Ialpha as a new therapeutic target in sepsis

Eaton, P. (Primary Investigator)

MRC Medical Research Council

1/03/2014 → 28/02/2018

Project: Research

Dietary electrophiles and healthy cardiovascular aging

Eaton, P. (Primary Investigator)

1/01/2014 → 31/12/2016

Project: Research

Targeting the oxidative activation of protein kinase G to limit injury during sepsis

Eaton, P. (Primary Investigator)

1/01/2014 → 31/12/2017

Project: Research

Lung protection from deflation during cardiac surgery with cardiopulmonary bypass: low frequency ventilation and/or novel xanthine therapy

Markou, T. (Primary Investigator), Chambers, D. (Co-Investigator) & Eaton, P. (Co-Investigator)

1/01/2014 → 31/12/2016

Project: Research

CARDIOREDOX - Redox sensing and signalling in cardiovascular health and disease

Eaton, P. (Primary Investigator)

EC European Commission

1/12/2013 → 30/11/2019

Project: Research

Defining how sulforaphane protects the heart from infarction

Eaton, P. (Primary Investigator)

BHF British Heart Foundation

1/05/2013 → 30/04/2016

Project: Research

CARDIOREDOX - Redox sensing and signalling in cardiovascular health and disease

Eaton, P. (Primary Investigator)

1/04/2013 → 31/03/2018

Project: Research

Protein kinase G oxidation in the pathogenesis of cardiovascular disease

Eaton, P. (Primary Investigator)

BHF British Heart Foundation

1/02/2013 → 31/01/2018

Project: Research

Protein kinase G lalpha disulfide oxidation and the pathogenesis of sepsis

Eaton, P. (Primary Investigator)

MRC Medical Research Council

1/11/2012 → 31/10/2015

Project: Research

Protein kinase G oxidation in the pathogenesis of cardiovascular disease

Eaton, P. (Primary Investigator)

1/10/2012 → 30/09/2017

Project: Research

An investigation into the physiological role of PKG1a activation by resveratrol

Eaton, P. (Primary Investigator)

1/10/2012 → 30/09/2017

Project: Research

Redox sensing and signalling in the cardiovascular system (Senior Investigator Award)

Eaton, P. (Primary Investigator)

1/03/2012 → 28/02/2017

Project: Research

Novel approaches to understanding oxidant sensing and signalling in the cardiovascular system

Eaton, P. (Primary Investigator), Khavandi, K. (Co-Investigator) & Shah, A. (Co-Investigator)

BHF British Heart Foundation

2/01/2012 → 31/07/2015

Project: Research

Redox regulation of soluble epoxide hydrolase in cardiovascular health and disease

Eaton, P. (Primary Investigator) & Charles, B. (Co-Investigator)

BHF British Heart Foundation

1/01/2011 → 31/03/2014

Project: Research

Redox regulation of soluble epoxide hydrolase in cardiovascaular health and disease

Eaton, P. (Primary Investigator) & Charles, B. (Co-Investigator)

1/11/2010 → 31/10/2013

Project: Research

Novel approaches to understanding oxidant sensing and signalling in the cardiovascular system

Eaton, P. (Primary Investigator) & Shah, A. (Co-Investigator)

1/10/2010 → 30/09/2013

Project: Research

Oxidant-induced activation of protein kinase A: from biochemistry to the cardiovascular physiology of a novel 'redox-dead' knock-in mouse

Eaton, P. (Primary Investigator)

MRC Medical Research Council

1/10/2010 → 30/11/2013

Project: Research

Understanding the redox control of soluble epoxide hydrolase and defining the downstream targets and signalling of its epoxysatrienoic acid substrates

Eaton, P. (Primary Investigator)

1/02/2010 → 31/01/2013

Project: Research

Redox and nitrosative regulation of cardiac remodelling: novel therapeutic approaches for heart failure

Eaton, P. (Primary Investigator) & Shah, A. (Primary Investigator)

Leducq Foundation

1/01/2010 → 31/12/2014

Project: Research

Hydrogen sulphide signalling and storage: defining its molecular basis

Eaton, P. (Primary Investigator)

1/08/2009 → 31/07/2012

Project: Research

Defining the role of RI interprotein disulfide bond formation in the redox regulation of type 1 PKA.

Eaton, P. (Primary Investigator)

1/11/2008 → 31/10/2011

Project: Research

Protein kinase G Ia: from novel substrates, structural analysis and cGMP-independentactivation to defining how it mediatescardioprotection

Burgoyne, J. (Primary Investigator) & Eaton, P. (Primary Investigator)

Wellcome Trust

1/08/2008 → 30/09/2012

Project: Research

Novel Roles of GAPDH as a peroxidase and as a peroxide sensor

Eaton, P. (Primary Investigator) & academic, A. (Primary Investigator)

1/07/2008 → 30/06/2011

Project: Research

15-deoxy-prostaglandin J2 and the heart: looking beyond PPARy and receptor mediated signalling

Eaton, P. (Primary Investigator)

BHF British Heart Foundation

1/05/2008 → 30/04/2011

Project: Research

BHF Centre of Research Excellence

Avkiran, M. (Primary Investigator), Blower, P. (Primary Investigator), Botnar, R. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Eaton, P. (Primary Investigator), Ehler, E. (Primary Investigator), Garcia-Manyes, S. (Primary Investigator), Gautel, M. (Primary Investigator), Geissmann, F. (Primary Investigator), Hussain, M. (Primary Investigator), Irving, M. (Primary Investigator), Kalra, L. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Nagel, E. (Primary Investigator), Otsu, K. (Primary Investigator), Razavi, R. (Primary Investigator), Ridley, A. (Primary Investigator), Shah, A. (Primary Investigator), Shanahan, C. (Primary Investigator), Smith, N. (Primary Investigator), Xu, Q. (Primary Investigator), Alastruey, J. (Co-Investigator), Ameer-Beg, S. (Co-Investigator), Bishop, M. (Co-Investigator), Brain, S. (Co-Investigator), Burgoyne, J. (Co-Investigator), Conte, M. (Co-Investigator), Dhanjal, T. (Co-Investigator), Eminaga, S. (Co-Investigator), Eykyn, T. (Co-Investigator), Gee, T. (Co-Investigator), Heintzmann, R. (Co-Investigator), Hughes, S. (Co-Investigator), Iskratsch, T. (Co-Investigator), Ivetic, A. (Co-Investigator), Jones, G. E. (Co-Investigator), Kentish, J. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Lombardi, G. (Co-Investigator), Mullen, G. (Co-Investigator), Okonko, D. (Co-Investigator), Parsons, M. (Co-Investigator), Pfuhl, M. (Co-Investigator), Phinikaridou, A. (Co-Investigator), Rodaway, A. (Co-Investigator), Shattock, M. (Co-Investigator), Sinkus, R. (Co-Investigator), Springett, R. (Co-Investigator), Steiner, R. (Co-Investigator), Stroud, M. (Co-Investigator), Sun, Y.-B. (Co-Investigator), Wardle, F. (Co-Investigator), Warren, D. (Co-Investigator), Webb, A. (Co-Investigator), Zampetaki, A. (Co-Investigator), Zeng, L. (Co-Investigator) & academic, A. (Co-Investigator)