Research output per year
Research output per year
- 1 - 50 out of 90 results
Search results
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2021
The drebrin/EB3 pathway regulates cytoskeletal dynamics to drive neuritogenesis in embryonic cortical neurons
Poobalasingam, T., Bianco, F., Oozeer, F. & Gordon-Weeks, P. R., 20 Sept 2021, (E-pub ahead of print) In: Journal of Neurochemistry. 160, 2, 18 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
2017
Drebrin-mediated microtubule-actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
Trivedi, N., Stabley, D. R., Cain, B., Howell, D., Laumonnerie, C., Ramahi, J. S., Temirov, J., Kerekes, R. A., Gordon-Weeks, P. R. & Solecki, D. J., 23 Feb 2017, In: Nature Communications. 8, p. 14484Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Citations (Scopus)144 Downloads (Pure) -
Phosphorylation of Drebrin and Its Role in Neuritogenesis
Gordon-Weeks, P. R., 2017, In: Advances in Experimental Medicine And Biology. 1006, p. 49-60 12 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
The drebrin/EB3 pathway drives invasive activity in prostate cancer
Dart, A. E., Worth, D. C., Muir, G., Chandra, A., Morris, J. D., McKee, C., Verrill, C., Bryant, R. J. & Gordon-Weeks, P. R., 20 Jul 2017, In: Oncogene. 36, 29, p. 4111–4123Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)209 Downloads (Pure) -
The Role of Drebrin in Cancer Cell Invasion
Dart, A. E. & Gordon-Weeks, P. R., 2017, In: Advances in Experimental Medicine And Biology. 1006, p. 375-389 15 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
2016
The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia
Stiber, J. A., Wu, J-H., Zhang, L., Nepliouev, I., Zhang, Z-S., Bryson, V. G., Brian, L., Bentley, R. C., Gordon-Weeks, P. R., Rosenberg, P. B. & Freedman, N. J., 24 Mar 2016, (E-pub ahead of print) In: Arteriosclerosis, Thrombosis, and Vascular Biology.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
The role of the drebrin/EB3/Cdk5 pathway in dendritic spine plasticity, implications for Alzheimer's disease
Gordon-Weeks, P. R., 27 Jun 2016, (E-pub ahead of print) In: Brain Research Bulletin. p. -Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)378 Downloads (Pure) -
2015
Drebrin regulates neuroblast migration in the postnatal Mammalian brain
Sonego, M., Oberoi, M., Stoddart, J., Gajendra, S., Hendricusdottir, R., Oozeer, F., Worth, D. C., Hobbs, C., Eickholt, B. J., Gordon-Weeks, P. R., Doherty, P. & Lalli, G., 6 May 2015, In: PLoS One. 10, 5, 26 p., e0126478.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)159 Downloads (Pure) -
2014
Neuronal cytoskeleton in synaptic plasticity and regeneration
Gordon-Weeks, P. R. & Fournier, A. E., Apr 2014, In: Journal of Neurochemistry. 129, 2, p. 206-212 7 p., N/A.Research output: Contribution to journal › Article › peer-review
Open Access74 Citations (Scopus) -
2013
Drebrin contains a cryptic F-actin-bundling activity regulated by Cdk5 phosphorylation
Worth, D. C., Daly, C. N., Geraldo, S., Gordon-Weeks, P. R. & Oozeer, F., 26 Aug 2013, In: Journal of Cell Biology. 202, 5, p. 793-806 14 p.Research output: Contribution to journal › Article › peer-review
82 Citations (Scopus) -
2012
Drebrin controls neuronal migration through the formation and alignment of the leading process
Dun, X., de Lima, T. B., Allen, J., Geraldo, S., Gordon-Weeks, P. & Chilton, J. K., Mar 2012, In: Molecular and Cellular Neurosciences. 49, 3, p. 341 - 350 10 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
MAP1B enhances microtubule assembly rates and axon extension rates in developing neurons
Tymanskyj, S. R., Scales, T. M. E. & Gordon-Weeks, P. R., Feb 2012, In: Molecular and Cellular Neurosciences. 49, 2, p. 110 - 119 10 p.Research output: Contribution to journal › Article › peer-review
59 Citations (Scopus) -
2010
Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain
Soutar, M. P. M., Kim, W-Y., Williamson, R., Peggie, M., Hastie, C. J., McLauchlan, H., Snider, W. D., Gordon-Weeks, P. R. & Sutherland, C., Nov 2010, In: Journal of Neurochemistry. 115, 4, p. 974 - 983 10 p.Research output: Contribution to journal › Article › peer-review
99 Citations (Scopus) -
Evolution of the spatial distribution of MAP1B phosphorylation sites in vertebrate neurons
Tymanskyj, S. R., Lin, S. & Gordon-Weeks, P. R., Jun 2010, In: Journal of Anatomy. 216, 6, p. 692 - 704 13 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
The neuron-specific isoform of glycogen synthase kinase-3 beta is required for axon growth
Castano, Z., Gordon-Weeks, P. R. & Kypta, R. M., Apr 2010, In: Journal of Neurochemistry. 113, 1, p. 117 - 130 14 p.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
2009
An alternatively spliced form of glycogen synthase kinase-3 beta is targeted to growing neurites and growth cones
Wood-Kaczmar, A., Kraus, M., Ishiguro, K., Philpott, K. L. & Gordon-Weeks, P. R., Oct 2009, In: Molecular and Cellular Neurosciences. 42, 3, p. 184 - 194 11 p.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus) -
Nonprimed and DYRK1A-primed GSK3 beta-phosphorylation sites on MAP1B regulate microtubule dynamics in growing axons
Scales, T. M. E., Lin, S., Kraus, M., Goold, R. G. & Gordon-Weeks, P. R., 15 Jul 2009, In: Journal of Cell Science. 122, 14, p. 2424 - 2435 12 p.Research output: Contribution to journal › Article › peer-review
73 Citations (Scopus) -
2008
DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing
Harrison, B., Kraus, M., Burch, L., Stevens, C., Craig, A., Gordon-Weeks, P. & Hupp, T. R., 11 Apr 2008, In: Journal of Biological Chemistry. 283, 15, p. 9999 - 10014 16 p.Research output: Contribution to journal › Article › peer-review
120 Citations (Scopus) -
Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis
Geraldo, S., Khanzada, U. K., Parsons, M., Chilton, J. K. & Gordon-Weeks, P. R., 2008, In: Nature Cell Biology. 10, 10, p. 1181 - 1189 9 p.Research output: Contribution to journal › Article › peer-review
198 Citations (Scopus) -
2007
The immunolocalization of the synaptic glycoprotein neuroplastin differs substantially between the human and the rodent brain
Bernstein, HG., Smalla, KH., Bogerts, B., Gordon-Weeks, PR., Beesley, PW., Gundelfinger, ED. & Kreutz, MR., 23 Feb 2007, In: Brain Research. 1134, 1, p. 107 - 112 6 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
2006
Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends
Peris, L., Thery, M., Faure, J., Saoudi, Y., Lafanechere, L., Chilton, J. K., Gordon-Weeks, P., Galjart, N., Bornens, M., Wordeman, L., Wehland, J., Andrieux, A. & Job, D., 11 Sept 2006, In: Journal of Cell Biology. 174, 6, p. 839 - 849 11 p.Research output: Contribution to journal › Article › peer-review
248 Citations (Scopus) -
2005
Glycogen synthase kinase-3beta phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons
Trivedi, N., Marsh, P., Goold, R. G., Wood-Kaczmar, A. & Gordon-Weeks, P. R., 1 Mar 2005, In: Journal of Cell Science. 118, 5, p. 993 - 1005 13 p.Research output: Contribution to journal › Article › peer-review
130 Citations (Scopus) -
The MAP kinase pathway is upstream of the activation of GSK3beta that enables it to phosphorylate MAP1B and contributes to the stimulation of axon growth
Goold, R. G. & Gordon-Weeks, P. R., Mar 2005, In: Molecular and Cellular Neurosciences. 28, 3, p. 524 - 534 11 p.Research output: Contribution to journal › Article › peer-review
88 Citations (Scopus) -
2003
Dynamic properties of APC-decorated microtubules in living cells.
Dayanandan, R., Butler, R., Gordon-Weeks, P. R., Matus, A., Kaech, S., Lovestone, S., Anderton, B. H. & Gallo, J. M., 1 Mar 2003, In: Cell Motility and the Cytoskeleton. 54, 3, p. 237 - 247 11 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Expression of the immunoglobulin superfamily neuroplastin adhesion molecules in adult and developing mouse cerebellum and their localisation to parasagittal stripes
Marzban, H., Khanzada, U., Shabir, S., Hawkes, R., Langnaese, K., Smalla, K. H., Bockers, T. M., Gundelfinger, E. D., Gordon-Weeks, P. R. & Beesley, P. W., 28 Jul 2003, In: Journal of Comparative Neurology. 462, 3, p. 286 - 301 16 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Inhibition of glycogen synthase kinase 3 beta in sensory neurons in culture alters filopodia dynamics and microtubule distribution in growth cones
Owen, R. & Gordon-Weeks, P. R., 1 Aug 2003, In: Molecular and Cellular Neurosciences. 23, 4, p. 626 - 637 12 p.Research output: Contribution to journal › Article › peer-review
89 Citations (Scopus) -
NGF activates the phosphorylation of MAP1B by GSK3 beta through the TrkA receptor and not the p75(NTR) receptor
Goold, R. G. & Gordon-Weeks, P. R., Nov 2003, In: Journal of Neurochemistry. 87, 4, p. 935 - 946 12 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
2002
Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons
Gonzalez-Billault, C., Owen, R., Gordon-Weeks, P. R. & Avila, J., 5 Jul 2002, In: Brain Research. 943, 1, p. 56 - 67 12 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
Partial regeneration and long-term survival of rat retinal ganglion cells after optic nerve crush is accompanied by altered expression, phosphorylation and distribution of cytoskeletal proteins
Dieterich, D. C., Trivedi, N., Engelmann, R., Gundelfinger, E. D., Gordon-Weeks, P. R. & Kreutz, M. R., 2002, In: European Journal of Neuroscience. 15, 9, p. 1433 - 1443 11 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
The non-immunosuppressive immunophilin ligand GPI-1046 potently stimulates regenerating axon growth from adult mouse dorsal root ganglia cultured in matrigel
Khan, Z., Ferrari, G., Kasper, M., Tonge, D. A., Steiner, J. P., Hamilton, G. S. & Gordon-Weeks, P. R., 11 Oct 2002, In: Neuroscience. 114, 3, p. 601 - 609 9 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons
Hall, A. C., Brennan, A., Goold, R. G., Cleverley, K., Lucas, F. R., Gordon-Weeks, P. R. & Salinas, P. C., 2002, In: Molecular and Cellular Neurosciences. 20, 2, p. 257 - 270 14 p.Research output: Contribution to journal › Article › peer-review
156 Citations (Scopus) -
2001
Microtubule-associated protein 1B phosphorylation by glycogen synthase kinase 3 beta is induced during PC12 cell differentiation
Goold, R. G. & Gordon-Weeks, P. R., 2001, In: Journal of Cell Science. 114, 23, p. 4273 - 4284 12 p.Research output: Contribution to journal › Article › peer-review
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1999
Glycogen synthase kinase 3beta phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones
Goold, R. G., Owen, R. & Gordon-Weeks, P. R., Oct 1999, In: Journal of Cell Science. 112, 19, p. 3373-84 12 p.Research output: Contribution to journal › Article › peer-review
252 Citations (Scopus) -
Monoclonal antibody 2G13, a new axonal growth cone marker
Stettler, O., Bush, M. S., Kasper, M., Schlosshauer, B. & Gordon-Weeks, P. R., 1999, In: Journal of Neurocytology. 28, 12, p. 1035 - 1044 10 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
The protein MAP-1B links GABA(c) receptors to the cytoskeleton at retinal synapses
Hanley, J. G., Koulen, P., Bedford, F., Gordon-Weeks, P. R. & Moss, S. J., 7 Jan 1999, In: NATURE. 397, 6714, p. 66-69 4 p.Research output: Contribution to journal › Article › peer-review
120 Citations (Scopus) -
1998
Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium
Lucas, F. R., Goold, R. G., Gordon-Weeks, P. R. & Salinas, P. C., May 1998, In: Journal of Cell Science. 111, 10, p. 1351-61 11 p.Research output: Contribution to journal › Article › peer-review
285 Citations (Scopus) -
1997
Localisation of microtubule-associated protein 1B phosphorylation sites recognised by monoclonal antibody SMI-31
Johnstone, M., Goold, R. G., Bei, D., Fischer, I. & Gordon-Weeks, P. R., Oct 1997, In: Journal of Neurochemistry. 69, 4, p. 1417-24 8 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
The neurofilament antibody RT97 recognises a developmentally regulated phosphorylation epitope on microtubule-associated protein 1B
Johnstone, M., Goold, R. G., Fischer, I. & Gordon-Weeks, P. R., Aug 1997, In: Journal of Anatomy. 191 , 2, p. 229-44 16 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
1996
An analysis of an axonal gradient of phosphorylated MAP 1B in cultured rat sensory neurons
Bush, M. S., Goold, R. G., Moya, F. & Gordon-Weeks, P. R., Feb 1996, In: European Journal of Neuroscience. 8, 2, p. 235-48 14 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
Expression of a developmentally regulated, phosphorylated isoform of microtubule-associated protein 1B in regenerating axons of the sciatic nerve
Bush, M. S., Tonge, D. A., Woolf, C. & Gordon-Weeks, P. R., Jul 1996, In: Neuroscience. 73, 2, p. 553-63 11 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Expression of a developmentally regulated, phosphorylated isoform of microtubule-associated protein 1B in sprouting and regenerating axons in vitro
Tonge, D. A., Golding, J. P. & Gordon-Weeks, P. R., Jul 1996, In: Neuroscience. 73, 2, p. 541-551 11 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Microtubule reorganization is obligatory for growth cone turning
Williamson, T., Gordon-Weeks, P. R., Schachner, M. & Taylor, J., 24 Dec 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 26, p. 15221-6 6 p.Research output: Contribution to journal › Article › peer-review
116 Citations (Scopus) -
1995
Phosphorylation of microtubule-associated protein IB and axonal growth
Gordon-Weeks, P. R., Johnstone, M. & Bush, M., Feb 1995, In: Biochemical Society Transactions. 23, 1, p. 37-40 4 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
1994
Distribution and expression of developmentally regulated phosphorylation epitopes on MAP 1B and neurofilament proteins in the developing rat spinal cord
Bush, M. S. & Gordon-Weeks, P. R., Nov 1994, In: Journal of Neurocytology. 23, 11, p. 682-98 17 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
Expression of PAC 1, an epitope associated with two synapse-enriched glycoproteins and a neuronal cytoskeleton-associated polypeptide in developing forebrain neurons
Willmott, T., Williamson, T. L., Mummery, R., Hawkes, R. B., Can, A., Gurd, J. W., Gordon-Weeks, P. R. & Beesley, P. W., Jan 1994, In: Neuroscience. 58, 1, p. 115-29 15 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
1993
A Phosphorylation Epitope on MAP 1B that is Transiently Expressed in Growing Axons in the Developing Rat Nervous System
Gordon-Weeks, P. R., Mansfield, S. G., Alberto, C., Johnstone, M. & Moya, F., 1 Oct 1993, In: European Journal of Neuroscience. 5, 10, p. 1302-11 10 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
Organization of microtubules in axonal growth cones: a role for microtubule-associated protein MAP 1B
Gordon-Weeks, P. R., Sept 1993, In: Journal of Neurocytology. 22, 9, p. 717-25 9 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor
Fan, J., Mansfield, S. G., Redmond, T., Gordon-Weeks, P. R. & Raper, J. A., May 1993, In: Journal of Cell Biology. 121, 4, p. 867-78 12 p.Research output: Contribution to journal › Article › peer-review
233 Citations (Scopus) -
1992
A study of the expression of laminin in the spinal cord of the frog during development and regeneration
Gordon-Weeks, P. R., Golding, J. P., Clarke, J. D. & Tonge, D., Sept 1992, In: Experimental Physiology. 77, 5, p. 681-692 12 p., N/A.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Characterisation of two novel glycoproteins in the membrane skeleton of the growth cone
Williamson, T. L., Gordon-Weeks, P. R. & Beesley, P. W., May 1992, In: Biochemical Society Transactions. 20, 2, p. 154SResearch output: Contribution to journal › Article › peer-review