King's College London

Research portal

Dr Rachel Sparks

  1. Computer-Assisted Versus Manual Planning for Stereotactic Brain Biopsy: A Retrospective Comparative Pilot Study

    Marcus, H. J., Vakharia, V. N., Sparks, R., Rodionov, R., Kitchen, N., McEvoy, A. W., Miserocchi, A., Thorne, L., Ourselin, S. & Duncan, J. S., 1 Apr 2020, In : Operative neurosurgery (Hagerstown, Md.). 18, 4, p. 417-422 6 p.

    Research output: Contribution to journalArticle

  2. Towards Uncertainty Quantification for Electrode Bending Prediction in Stereotactic Neurosurgery

    Granados, A., Lucena, O., Vakharia, V., Miserocchi, A., McEvoy, A. W., Vos, S. B., Rodionov, R., Duncan, J. S., Sparks, R. & Ourselin, S., Apr 2020, ISBI 2020 - 2020 IEEE International Symposium on Biomedical Imaging. IEEE Computer Society, p. 674-677 4 p. 9098730. (Proceedings - International Symposium on Biomedical Imaging; vol. 2020-April).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  3. Computer-assisted planning for minimally invasive anterior two-thirds laser corpus callosotomy: A feasibility study with probabilistic tractography validation: Automated laser callosotomy trajectory planning

    Vakharia, V. N., Sparks, R. E., Vos, S. B., Bezchlibnyk, Y., Mehta, A. D., Willie, J. T., Wu, C., Sharan, A., Ourselin, S. & Duncan, J. S., 1 Jan 2020, In : NeuroImage: Clinical. 25, 102174.

    Research output: Contribution to journalArticle

  4. Computer-Assisted Planning for Stereoelectroencephalography (SEEG)

    Vakharia, V. N., Sparks, R., Miserocchi, A., Vos, S. B., O’Keeffe, A., Rodionov, R., McEvoy, A. W., Ourselin, S. & Duncan, J. S., 1 Oct 2019, In : Neurotherapeutics. 16, 4, p. 1183-1197 15 p.

    Research output: Contribution to journalArticle

  5. The Effect of Vascular Segmentation Methods on Stereotactic Trajectory Planning for Drug-Resistant Focal Epilepsy: A Retrospective Cohort Study

    Vakharia, V. N., Sparks, R., Vos, S. B., McEvoy, A. W., Miserocchi, A., Ourselin, S. & Duncan, J. S., 1 Oct 2019, In : World Neurosurgery: X. 4, 100057.

    Research output: Contribution to journalArticle

  6. Multicenter validation of automated trajectories for selective laser amygdalohippocampectomy

    Vakharia, V. N., Sparks, R. E., Li, K., O'Keeffe, A. G., Pérez-García, F., França, L. G. S., Ko, A. L., Wu, C., Aronson, J. P., Youngerman, B. E., Sharan, A., McKhann, G., Ourselin, S. & Duncan, J. S., 1 Sep 2019, In : Epilepsia. 60, 9, p. 1949-1959 11 p.

    Research output: Contribution to journalArticle

  7. Stereoelectroencephalography electrode placement: Detection of blood vessel conflicts

    Li, K., Vakharia, V. N., Sparks, R., Rodionov, R., Vos, S. B., McEvoy, A. W., Miserocchi, A., Wang, M., Ourselin, S. & Duncan, J. S., 1 Sep 2019, In : Epilepsia. 60, 9, p. 1942-1948 7 p.

    Research output: Contribution to journalArticle

  8. Automated fiber tract reconstruction for surgery planning: Extensive validation in language-related white matter tracts

    Mancini, M., Vos, S. B., Vakharia, V. N., O'Keeffe, A. G., Trimmel, K., Barkhof, F., Dorfer, C., Soman, S., Winston, G. P., Wu, C., Duncan, J. S., Sparks, R. & Ourselin, S., 28 May 2019, In : NeuroImage: Clinical. 23, 9 p., 101883.

    Research output: Contribution to journalArticle

  9. Association of Piriform Cortex Resection With Surgical Outcomes in Patients With Temporal Lobe Epilepsy

    Galovic, M., Baudracco, I., Wright-Goff, E., Pillajo, G., Nachev, P., Wandschneider, B., Woermann, F., Thompson, P., Baxendale, S., McEvoy, A. W., Nowell, M., Mancini, M., Vos, S. B., Winston, G. P., Sparks, R., Prados, F., Miserocchi, A., de Tisi, J., Van Graan, L. A., Rodionov, R. & 13 others, Wu, C., Alizadeh, M., Kozlowski, L., Sharan, A. D., Kini, L. G., Davis, K. A., Litt, B., Ourselin, S., Moshé, S. L., Sander, J. W. A., Löscher, W., Duncan, J. S. & Koepp, M. J., 11 Mar 2019, In : JAMA Neurology. 76, 6, p. 690-700 11 p.

    Research output: Contribution to journalArticle

  10. Computer-assisted planning for the insertion of stereoelectroencephalography electrodes for the investigation of drug-resistant focal epilepsy: an external validation study

    Vakharia, V. N., Sparks, R., Rodionov, R., Vos, S. B., Dorfer, C., Miller, J., Nilsson, D., Tisdall, M., Wolfsberger, S., McEvoy, A. W., Miserocchi, A., Winston, G. P., O'Keeffe, A. G., Ourselin, S. & Duncan, J. S., Feb 2019, In : Journal of Neurosurgery. 130, 2, p. 601-610 10 p.

    Research output: Contribution to journalArticle

  11. A Generative Model of Hyperelastic Strain Energy Density Functions for Real-Time Simulation of Brain Tissue Deformation

    Granados, A., Schweiger, M., Vakharia, V., McEvoy, A. W., Miserocchi, A., Duncan, J. S., Sparks, R. & Ourselin, S., 1 Jan 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 - 22nd International Conference, Proceedings. Shen, D., Yap, P-T., Liu, T., Peters, T. M., Khan, A., Staib, L. H., Essert, C. & Zhou, S. (eds.). SPRINGER, p. 218-226 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11768 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  12. Optimizing Trajectories for Cranial Laser Interstitial Thermal Therapy Using Computer-Assisted Planning: A Machine Learning Approach

    Li, K., Vakharia, V. N., Sparks, R., França, L. G. S., Granados, A., McEvoy, A. W., Miserocchi, A., Wang, M., Ourselin, S. & Duncan, J. S., 5 Dec 2018, In : Neurotherapeutics. 16, 1, p. 182-1891

    Research output: Contribution to journalReview article

  13. Automatic segmentation of stereoelectroencephalography (SEEG) electrodes post-implantation considering bending

    Granados, A., Vakharia, V., Rodionov, R., Schweiger, M., Vos, S. B., O’Keeffe, A. G., Li, K., Wu, C., Miserocchi, A., McEvoy, A. W., Clarkson, M. J., Duncan, J. S., Sparks, R. & Ourselin, S., Jun 2018, In : International Journal of Computer Assisted Radiology and Surgery. 13, 6, p. 935-946 12 p.

    Research output: Contribution to journalArticle

  14. Automated trajectory planning for laser interstitial thermal therapy in mesial temporal lobe epilepsy

    Vakharia, V. N., Sparks, R., Li, K., O'Keeffe, A. G., Miserocchi, A., McEvoy, A. W., Sperling, M. R., Sharan, A., Ourselin, S., Duncan, J. S. & Wu, C., Apr 2018, In : Epilepsia. 59, 4, p. 814-824 11 p.

    Research output: Contribution to journalArticle

  15. Improving patient safety during introduction of novel medical devices through cumulative summation analysis

    Vakharia, V. N., Rodionov, R., McEvoy, A. W., Miserocchi, A., Sparks, R., O’Keeffe, A. G., Ourselin, S. & Duncan, J. S., 16 Feb 2018, In : Journal of Neurosurgery. p. 1-7 7 p.

    Research output: Contribution to journalArticle

  16. A Machine Learning Approach to Predict Instrument Bending in Stereotactic Neurosurgery

    Granados, A., Mancini, M., Vos, S. B., Lucena, O., Vakharia, V., Rodionov, R., Miserocchi, A., McEvoy, A. W., Duncan, J. S., Sparks, R. & Ourselin, S., 2018, International Conference on Medical Image Computing and Computer-Assisted Intervention. p. 238-246 9 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  17. Anatomy-driven multiple trajectory planning (ADMTP) of intracranial electrodes for epilepsy surgery

    Sparks, R., Vakharia, V., Rodionov, R., Vos, S. B., Diehl, B., Wehner, T., Miserocchi, A., McEvoy, A. W., Duncan, J. S. & Ourselin, S., Aug 2017, In : International Journal of Computer Assisted Radiology and Surgery. 12, 8, p. 1245-1255 11 p.

    Research output: Contribution to journalArticle

  18. Resection planning in extratemporal epilepsy surgery using 3D multimodality imaging and intraoperative MRI

    Nowell, M., Sparks, R., Zombori, G., Miserocchi, A., Rodionov, R., Diehl, B., Wehner, T., White, M., Ourselin, S., McEvoy, A. & Duncan, J., 4 Jul 2017, In : British Journal of Neurosurgery. 31, 4, p. 468-470 3 p.

    Research output: Contribution to journalComment/debate

  19. Accuracy of intracranial electrode placement for stereoencephalography: A systematic review and meta-analysis

    Vakharia, V. N., Sparks, R., O'Keeffe, A. G., Rodionov, R., Miserocchi, A., McEvoy, A., Ourselin, S. & Duncan, J., Jun 2017, In : Epilepsia. 58, 6, p. 921-932 12 p.

    Research output: Contribution to journalReview article

  20. Connecting Markov random fields and active contour models: application to gland segmentation and classification

    Xu, J., Monaco, J. P., Sparks, R. & Madabhushi, A., 28 Mar 2017, In : Journal of Medical Imaging. 4, 2, p. 021107 1 p.

    Research output: Contribution to journalArticle

  21. Automated multiple trajectory planning algorithm for the placement of stereo-electroencephalography (SEEG) electrodes in epilepsy treatment

    Sparks, R., Zombori, G., Rodionov, R., Nowell, M., Vos, S. B., Zuluaga, M. A., Diehl, B., Wehner, T., Miserocchi, A., McEvoy, A. W., Duncan, J. S. & Ourselin, S., Jan 2017, In : International Journal of Computer Assisted Radiology and Surgery. 12, 1, p. 123-136 14 p.

    Research output: Contribution to journalArticle

  22. Comparison of computer-assisted planning and manual planning for depth electrode implantations in epilepsy

    Nowell, M., Sparks, R., Zombori, G., Miserocchi, A., Rodionov, R., Diehl, B., Wehner, T., Baio, G., Trevisi, G., Tisdall, M., Ourselin, S., McEvoy, A. W. & Duncan, J., 1 Jun 2016, In : Journal of Neurosurgery. 124, 6, p. 1820-1828 9 p.

    Research output: Contribution to journalArticle

  23. A pipeline for 3D multimodality image integration and computer-assisted planning in epilepsy surgery

    Nowell, M., Rodionov, R., Zombori, G., Sparks, R., Rizzi, M., Ourselin, S., Miserocchi, A., McEvoy, A. & Duncan, J., 20 May 2016, In : Journal of Visualized Experiments. 2016, 111, e53450.

    Research output: Contribution to journalArticle

  24. Efficient anatomy driven automated multiple trajectory planning for intracranial electrode implantation

    Sparks, R., Zombori, G., Rodionov, R., Zuluaga, M. A., Diehl, B., Wehner, T., Miserocchi, A., McEvoy, A. W., Duncan, J. S. & Ourselin, S., 1 Jan 2016, Medical Image Computing and Computer-Assisted Intervention - MICCAI 2016 - 19th International Conference, Proceedings. Springer Verlag, Vol. 9900 LNCS. p. 542-550 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9900 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  25. Identifying in vivo DCE MRI markers associated with microvessel architecture and gleason grades of prostate cancer

    Singanamalli, A., Rusu, M., Sparks, R. E., Shih, N. N. C., Ziober, A., Wang, L. P., Tomaszewski, J., Rosen, M., Feldman, M. & Madabhushi, A., 1 Jan 2016, Journal of Magnetic Resonance Imaging. John Wiley and Sons Inc., p. 149-158 10 p. (Journal of Magnetic Resonance Imaging; vol. 43).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  26. Multiattribute probabilistic prostate elastic registration (MAPPER): Application to fusion of ultrasound and magnetic resonance imaging

    Sparks, R., Nicolas Bloch, B., Feleppa, E., Barratt, D., Moses, D., Ponsky, L. & Madabhushi, A., 1 Mar 2015, Medical Physics. AAPM - American Association of Physicists in Medicine, p. 1153-1163 11 p. (Medical Physics; vol. 42).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  27. Utility of 3D multimodality imaging in the implantation of intracranial electrodes in epilepsy

    Nowell, M., Rodionov, R., Zombori, G., Sparks, R., Winston, G., Kinghorn, J., Diehl, B., Wehner, T., Miserocchi, A., McEvoy, A. W., Ourselin, S. & Duncan, J., Mar 2015, In : Epilepsia. 56, 3, p. 403-413 11 p.

    Research output: Contribution to journalArticle

  28. Co-occurring gland angularity in localized subgraphs: Predicting biochemical recurrence in intermediate-risk prostate cancer patients

    Lee, G., Sparks, R., Ali, S., Shih, N. N. C., Feldman, M. D., Spangler, E., Rebbeck, T., Tomaszewski, J. E. & Madabhushi, A., 29 May 2014, PLoS ONE. Public Library of Science, (PLoS ONE; vol. 9).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  29. Intense focused ultrasound stimulation can safely stimulate inflamed subcutaneous tissue and assess allodynia

    McClintic, A. M., Garcia, J. B., Gofeld, M., Kliot, M., Kucewicz, J. C., Loeser, J. D., Pederson, K. D., Sparks, R. E., Terman, G. W., Tych, R. E. & Mourad, P. D., 25 Feb 2014, Journal of Therapeutic Ultrasound. BIOMED CENTRAL LTD, (Journal of Therapeutic Ultrasound; vol. 2).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. Spectral embedding-based registration (SERg) for multimodal fusion of prostate histology and MRI

    Hwuang, E., Rusu, M., Karthigeyan, S., Agner, S. C., Sparks, R., Shih, N., Tomaszewski, J. E., Rosen, M., Feldman, M. & Madabhushi, A., 2014, SPIE Medical Imaging. p. 90343P-90343P-15 (SPIE Medical Imaging; vol. 9034).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  31. Explicit shape descriptors: Novel morphologic features for histopathology classification

    Sparks, R. & Madabhushi, A., Dec 2013, Medical Image Analysis. p. 997-1009 13 p. (Medical Image Analysis; vol. 17).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  32. Anisotropic smoothing regularization (AnSR) in Thirion's Demons registration evaluates brain MRI tissue changes post-laser ablation

    Hwuang, E., Danish, S., Rusu, M., Sparks, R., Toth, R. & Madabhushi, A., 2013, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. p. 4006-4009 4 p. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  33. Co-occurring gland tensors in localized cluster graphs: Quantitative histomorphometry for predicting biochemical recurrence for intermediate grade prostate cancer

    Lee, G., Sparks, R., Ali, S., Madabhushi, A., Feldman, M. D., Master, S. R., Shih, N. & Tomaszewski, J. E., 2013, Proceedings - International Symposium on Biomedical Imaging. p. 113-116 4 p. (Proceedings - International Symposium on Biomedical Imaging).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  34. Identifying in vivo DCE MRI parameters correlated with ex vivo quantitative microvessel architecture: A radiohistomorphometric approach

    Gurcan, M. N. (ed.), Madabhushi, A., Singanamalli, A., Sparks, R., Rusu, M., Shih, N., Ziober, A., Tomaszewski, J., Rosen, M., Feldman, M. & Madabhushi, A., 2013, Proc SPIE. Gurcan, M. N. & Madabhushi, A. (eds.). SPIE - INT SOC OPTICAL ENGINEERING, p. 867604 1 p. (Proc SPIE; vol. 8676).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  35. Neuropathic Tissue Responds Preferentially to Stimulation by Intense Focused Ultrasound

    Tych, R. E., Gofeld, M., Jarvik, J. G., Kliot, M., Loeser, J. D., McClintic, A. M., Ollos, R. J., Pederson, K. D., Sparks, R. E., Terman, G. W. & Mourad, P. D., 2013, Ultrasound in Medicine and Biology. Elsevier USA, p. 111-116 6 p. (Ultrasound in Medicine and Biology; vol. 39).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  36. Statistical shape model for manifold regularization: Gleason grading of prostate histology

    Sparks, R. & Madabhushi, A., 2013, Computer Vision and Image Understanding. ACADEMIC PRESS INC, p. 1138-1146 9 p. (Computer Vision and Image Understanding; vol. 117).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  37. Medial axis based statistical shape model (MASSM): Applications to 3D prostate segmentation on MRI

    Toth, R., Sparks, R. & Madabhushi, A., 2011, Proceedings - International Symposium on Biomedical Imaging. p. 1463-1466 4 p. (Proceedings - International Symposium on Biomedical Imaging).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  38. Out-of-sample extrapolation using semi-supervised manifold learning (OSE-SSL): Content-based image retrieval for prostate histology grading

    Sparks, R. & Madabhushi, A., 2011, Proceedings - International Symposium on Biomedical Imaging. p. 734-737 4 p. (Proceedings - International Symposium on Biomedical Imaging).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  39. Segmentation of nodular medulloblastoma using random walker and hierarchical normalized cuts

    Tchikindas, L., Sparks, R., Baccon, J., Ellison, D., Judkins, A. R. & Madabhushi, A., 2011, 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011. (2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  40. An integrated framework for analyzing three-dimensional shape differences: Evaluating prostate morphometry

    Sparks, R., Toth, R., Chappelow, J., Xiao, G. & Madabhushi, A., 2010, 2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings. p. 1081-1084 4 p. (2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  41. High-throughput prostate cancer gland detection, segmentation, and classification from digitized needle core biopsies

    Xu, J., Sparks, R., Janowcyzk, A., Tomaszewski, J. E., Feldman, M. D. & Madabhushi, A., 2010, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). p. 77-88 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 6367 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  42. Novel morphometric based classification via diffeomorphic based shape representation using manifold learning

    Sparks, R. & Madabhushi, A., 2010, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). p. 658-665 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 6363 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingChapter

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