Search results

• 2022

  Pluripotent stem cell-derived hepatocytes inhibit T cell proliferation in vitro through tryptophan starvation

  Romano, M., Elgueta, R., McCluskey, D., Ortega-Prieto, A. M., Stolarczyk, E., Dazzi, F., Lucendo-Villarin, B., Meseguer-Ripolles, J., Williams, J., Fanelli, G., Hay, D. C., Watt, F. M. & Lombardi, G., 1 Jan 2022, In: Cells. 11, 1, 24.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • T Cell Proliferation 100%
  • Somatic Cell 10%
  • Host Immune Response 10%
  • Programmed Death-Ligand 1 10%
  • Co-Stimulatory Molecule 10%
  4 Citations (Scopus)
• 2019

  Characterizing the B-Cell and Humoral Response in Tertiary Lymphoid Organs in Kidney Allografts

  Nowocin, A. K., Meader, L., Brown, K., Elgueta, R. & Wong, W., 1 Jun 2019, In: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 17, 3, p. 330-338 9 p.

  Research output: Contribution to journal › Article › peer-review

  • B Cell 100%
  • Lymphoid Organ 100%
  • Kidney Allograft 100%
  • Kidney 44%
  • C57BL/6 33%
  6 Citations (Scopus)
• 2018

  Galectin-1 is required for the regulatory function of B cells

  Alhabbab, R., Blair, P., Smyth, L. A., Ratnasothy, K., Peng, Q., Moreau, A., Lechler, R., Elgueta, R. & Lombardi, G., 2018, In: Scientific Reports. 8, 2725 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Galectin-1 100%
  • Wild Type 30%
  • Tumor Necrosis Factor 20%
  • Molecule 10%
  • MHC Class I 10%
  25 Citations (Scopus)

  109 Downloads (Pure)

• Nox2 in regulatory T cells promotes angiotensin II–induced cardiovascular remodeling

  Emmerson, A., Cellone Trevelin, S., Mongue-Din, H., Becker, P. D., Ortiz, C., Smyth, L. A., Peng, Q., Elgueta, R., Sawyer, G., Ivetic, A., Lechler, R. I., Lombardi, G. & Shah, A. M., 2 Jul 2018, In: The Journal of clinical investigation. 128, 7, p. 3088–3101

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Regulatory T Cell 100%
  • Animal 25%
  • Superoxide 25%
  • Effector Cell 10%
  55 Citations (Scopus)

  107 Downloads (Pure)

• Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations

  Philippeos, C., Telerman, S. B., Oulès, B., Pisco, A. O., Shaw, T. J., Elgueta, R., Lombardi, G., Driskell, R. R., Soldin, M., Lynch, M. D. & Watt, F. M., 30 Apr 2018, In: Journal of Investigative Dermatology. 138, 4, p. 811-825 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gene Expression Assay 100%
  • Gene Expression Profiling 100%
  • Dermis 42%
  • Lineages 14%
  • Wnt Signaling 14%
  289 Citations (Scopus)

  668 Downloads (Pure)
• 2016

  Endothelial Plasmalemma Vesicle-Associated Protein Regulates the Homeostasis of Splenic Immature B Cells and B-1 B Cells.

  Elgueta, R., Tse, D., Deharvengt, S. J., Luciano, M., Carrière, C., Noelle, R. & Stan, R. V., 15 Nov 2016, In: Journal of Immunology. 197, 10, p. 3970 3981 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Protein 100%
  • Homeostasis 100%
  • Cell Membrane 100%
  • B Cell 100%
  • Lymph Node 18%
  13 Citations (Scopus)

  201 Downloads (Pure)

• IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses

  Nova Lamperti, E. A., Fanelli, G., Becker, P. D., Chana, P., Elgueta Rebolledo, R. A., Dodd, P., Lord, G. M., Lombardi, G. & Hernandez Fuentes, M. P., 22 Jan 2016, In: Scientific Reports. 6, p. 20044 20044.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • T-Helper Cell 100%
  • T Cell Proliferation 37%
  • Adoptive Immunity 12%
  • T Cell Activation 12%
  • Tumor Necrosis Factor 12%
  65 Citations (Scopus)

  235 Downloads (Pure)

• Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response

  Marks, E., Ortiz, C., Pantazi, E., Bailey, C. S., Lord, G. M., Waldschmidt, T. J., Noelle, R. J. & Elgueta, R., 23 Dec 2016, In: Frontiers in Immunology. 7, 643

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B Cell 100%
  • Cell Lineage 16%
  • Inflammation 8%
  • Immunoglobulin A 8%
  • Humoral Immunity 8%
  16 Citations (Scopus)
• 2015

  CCR6-Dependent Positioning of Memory B Cells Is Essential for Their Ability To Mount a Recall Response to Antigen

  Elgueta, R., Marks, E., Nowak, E., Menezes, S., Benson, M., Raman, V. S., Ortiz, C., O'Connell, S., Hess, H., Lord, G. M. & Noelle, R., 15 Jan 2015, In: Journal of Immunology. 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antigen 100%
  • Memory B Cell 100%
  • B Cell 50%
  • Humoral Immunity 50%
  • Chemokine Response 50%
  61 Citations (Scopus)

  184 Downloads (Pure)

• Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model

  Alhabbab, R., Blair, P., Elgueta, R., Stolarczyk, E., Marks, E., Becker, P. D., Ratnasothy, K., Smyth, L., Safinia, N., Sharif-Paghaleh, E., O'Connell, S., Noelle, R. J., Lord, G. M., Howard, J. K., Spencer, J., Lechler, R. I. & Lombardi, G., 25 Jun 2015, In: Scientific Reports. 5, 11554.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • B Cell 100%
  • Transplant Procedure 8%
  31 Citations (Scopus)

  195 Downloads (Pure)

• Retinoic Acid is essential for Th1 cell lineage stability and prevents transition to a th17 cell program

  Brown, C. C., Esterhazy, D., Sarde, A., London, M., Pullabhatla, V., Osma-Garcia, I., Al-Bader, R., Ortiz, C., Elgueta, R., Arno, M., de Rinaldis, E., Mucida, D., Lord, G. M. & Noelle, R. J., 17 Mar 2015, In: Immunity. 42, 3, p. 499-511 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • T Helper 1 Cell 100%
  • Retinoic Acid 100%
  • Lineages 75%
  • T-Helper Cell 50%
  • Plasticity 50%
  124 Citations (Scopus)

  192 Downloads (Pure)

• Retinoic Acid Signaling in B Cells Is Essential for Oral Immunization and Microflora Composition

  Pantazi, E., Marks, E., Stolarczyk, E., Lycke, N., Noelle, R. J. & Elgueta, R., 15 Aug 2015, In: Journal of Immunology. 195, 4, p. 1368-1371 4 p.

  Research output: Contribution to journal › Article › peer-review

  • B Cell 100%
  • Immunization 100%
  • Tretinoin 100%
  • Immunoglobulin A 50%
  • Humoral Immunity 33%
  46 Citations (Scopus)
• 2014

  Transitional-2 B cells acquire regulatory function during tolerance induction and contribute to allograft survival

  Moreau, A., Blair, P. A., Chai, J.-G., Ratnasothy, K., Stolarczyk, E., Alhabbab, R., Rackham, C. L., Jones, P. M., Smyth, L., Elgueta, R., Howard, J. K., Lechler, R. I. & Lombardi, G., 2014, (E-pub ahead of print) In: European Journal of Immunology. p. 843-853 11 p.

  Research output: Contribution to journal › Article › peer-review

  • B Cell 100%
  • Regulatory T Cell 16%
  • T Cell Activation 8%
  • Regulatory B Cells 8%
  40 Citations (Scopus)
• 2012

  The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition

  Stan, R. V., Tse, D., Deharvengt, S. J., Smits, N. C., Xu, Y., Luciano, M. R., McGarry, C. L., Buitendijk, M., Nemani, K. V., Elgueta, R., Kobayashi, T., Shipman, S. L., Moodie, K. L., Daghlian, C. P., Ernst, P. A., Lee, H.-K., Suriawinata, A. A., Schned, A. R., Longnecker, D. S. & Fiering, S. N. & 4 others, Noelle, R. J., Gimi, B., Shworak, N. W. & Carrière, C., 11 Dec 2012, In: Developmental Cell. 23, 6, p. 1203-18 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Endothelium 100%
  • Blood Vessel Permeability 100%
  • Protein 100%
  • Genetics 50%
  • Gene 50%
  176 Citations (Scopus)

  268 Downloads (Pure)
• 2011

  A retinoic acid-dependent checkpoint in the development of CD4+ T cell-mediated immunity

  Pino-Lagos, K., Guo, Y., Brown, C., Alexander, M. P., Elgueta, R., Bennett, K. A., De Vries, V., Nowak, E., Blomhoff, R., Sockanathan, S., Chandraratna, R. A., Dmitrovsky, E. & Noelle, R. J., 29 Aug 2011, In: Journal of Experimental Medicine. 208, 9, p. 1767-1775 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Inflammation 100%
  • T-Helper Cell 100%
  • Adoptive Immunity 100%
  • Vaccination 33%
  106 Citations (Scopus)

  1596 Downloads (Pure)
• 2009

  Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals

  Benson, M. J., Elgueta, R., Schpero, W., Molloy, M., Zhang, W., Usherwood, E. & Noelle, R. J., 31 Aug 2009, In: The Journal of experimental medicine. 206, 9, p. 2013-25 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Memory B Cell 100%
  • Differentiation 66%
  • Analysis 16%
  • Protein 16%
  • B Cell 16%
  68 Citations (Scopus)

  162 Downloads (Pure)

• Mast cell degranulation breaks peripheral tolerance

  De Vries, V. C., Wasiuk, A., Bennett, K. A., Benson, M. J., Elgueta, R., Waldschmidt, T. J. & Noelle, R. J., Oct 2009, In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9, 10, p. 2270-2280 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Immune Tolerance 100%
  • Mast Cell 60%
  • Inflammation 40%
  • Regulatory T Cell 20%
  • Immunoglobulin E 20%
  105 Citations (Scopus)

  153 Downloads (Pure)

• Molecular mechanism and function of CD40/CD40L engagement in the immune system

  Elgueta, R., Benson, M. J., De Vries, V. C., Wasiuk, A., Guo, Y. & Noelle, R. J., 21 Apr 2009, In: Immunological Reviews. 229, 1, p. 152-72 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • B Cell 100%
  • Adaptive Immune System 100%
  • Antigen 66%
  • Adoptive Immunity 33%
  • Humoral Immunity 33%
  1148 Citations (Scopus)

  1920 Downloads (Pure)

• Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity

  Cubillos-Ruiz, J. R., Engle, X., Scarlett, U. K., Martinez, D., Barber, A., Elgueta, R., Wang, L., Nesbeth, Y., Durant, Y., Gewirtz, A. T., Sentman, C. L., Kedl, R. & Conejo-Garcia, J. R., 13 Aug 2009, In: The Journal of clinical investigation. 119, 8, p. 2231-2244 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dendritic Cell 100%
  • Immunosuppressive Drug 33%
  • TLR3 33%
  • Immunosuppression 16%
  • Myeloid Differentiation 16%
  195 Citations (Scopus)

  198 Downloads (Pure)

• The enigmatic role of mast cells in dominant tolerance

  de Vries, V. C., Pino-Lagos, K., Elgueta, R. & Noelle, R. J., Aug 2009, In: Current Opinion in Organ Transplantation. 14, 4, p. 332-337 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mast Cell 100%
  • Regulatory T Cell 80%
  • Immune Tolerance 30%
  • Immunosuppressive Drug 20%
  • Organ Transplantation 10%
  27 Citations (Scopus)

  244 Downloads (Pure)
• 2008

  B cell survival: an unexpected mechanism of lymphocyte vitality

  Benson, M. J., Elgueta, R. & Noelle, R. J., 20 May 2008, (E-pub ahead of print) In: Immunology and Cell Biology. 86, 6, p. 485-486 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  7 Citations (Scopus)

  152 Downloads (Pure)