Research output per year
Research output per year
- 23 results
Search results
-
2023
Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study
Papa, S., Adami, A., Metoudi, M., Beatson, R., George, M. S., Achkova, D., Williams, E., Arif, S., Reid, F., Elstad, M., Beckley-Hoelscher, N., Douri, A., Delord, M., Lyne, M., Shivapatham, D., Fisher, C., Hope, A., Gooljar, S., Mitra, A., Gomm, L., & 16 others, 15 Jun 2023, In: Journal for ImmunoTherapy of Cancer. 11, 6, e007162.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
LYVE-1 + macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer
Anstee, J. E., Feehan, K. T., Opzoomer, J. W., Dean, I., Muller, H. P., Bahri, M., Cheung, T. S., Liakath-Ali, K., Liu, Z., Choy, D., Caron, J., Sosnowska, D., Beatson, R., Muliaditan, T., An, Z., Gillett, C. E., Lan, G., Zou, X., Watt, F. M., Ng, T., & 5 others, 11 Sept 2023, In: Developmental Cell. 58, 17, p. 1548-1561.e10Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
2022
BNT162b2 COVID-19 and ChAdOx1 nCoV-19 vaccination in patients with myelodysplastic syndromes
Abdul-Jawad, S., Beatson, R., Lechmere, T., Graham, R., Alaguthurai, T., Graham, C., Vidler, J., Kulasekararaj, A., Patten, P. E., Doores, K. J. & Irshad, S., May 2022, In: Haematologica. 107, 5, p. 1181-1184 4 p.Research output: Contribution to journal › Letter › peer-review
Open AccessFile6 Citations (Scopus)53 Downloads (Pure) -
HER2 mediates PSMA/mGluR1-driven resistance to the DS-7423 dual 2 PI3K/mTOR inhibitor in PTEN wild-type prostate cancer models: PTEN-wt PCa overcomes PI3K inhibition via mGluR1 signaling
Gómez, V., Galazi, M., Weitsman, G., Monypenny of Pitmilly, J., Al-Salemee, F., Barber, P., Ng, K., Beatson, R., Szokol, B., Orfi, L., Mullen, G., Vanhaesebroeck, B., Chowdhury, S., Leung, H. Y. & Ng, T., 19 Jan 2022, (Accepted/In press) In: MOLECULAR CANCER THERAPEUTICS.Research output: Contribution to journal › Article › peer-review
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HER2 Mediates PSMA/mGluR1-Driven Resistance to the DS-7423 Dual PI3K/mTOR Inhibitor in PTEN Wild-type Prostate Cancer Models
Gómez, V., Galazi, M., Weitsman, G., Monypenny, J., Al-Salemee, F., Barber, P. R., Ng, K., Beatson, R., Szokol, B., Orfi, L., Mullen, G., Vanhaesebroeck, B., Chowdhury, S., Leung, H. Y. & Ng, T., 1 Apr 2022, In: Molecular Cancer Therapeutics. 21, 4, p. 667-676 10 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
2021
Apoptosis in the Pancreatic Cancer TumorMicroenvironment— The Double-Edged Sword of Cancer-Associated Fibroblasts
Pfeifer, E., Burchell, J., Dazzi, F., Sarker, D. & Beatson, R., 1 Jul 2021, In: Cells. 10, 1653, 18 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile119 Downloads (Pure) -
Identification of chlorophyll a-b binding protein AB96 as a novel TGFβ1 neutralizing agent
Lynham, S., Grundland Freie, F., Puri, N., O'Reilly, N., Mitchell, G., Wells, T., Willcox, M. & Beatson, R., Dec 2021, In: Scientific Reports. 11, 1, 7740.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)94 Downloads (Pure) -
2020
Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype
Beatson, R., Graham, R., Grundland Freile, F., Cozzetto, D., Kannambath, S., Pfeifer, E., Woodman, N., Owen, J., Nuamah, R., Mandel, U., Pinder, S., Gillett, C., Noll, T., Bouybayoune, I., Taylor-Papadimitriou, J. & Burchell, J. M., 1 Dec 2020, In: Communications Biology. 3, 1, 644.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Citations (Scopus)146 Downloads (Pure) -
Mucins and their receptors in chronic lung disease
Denneny, E., Sahota, J., Beatson, R., Thornton, D., Burchell, J. & Porter, J., 1 Jan 2020, In: Clinical and Translational Immunology. 9, 3, e01120.Research output: Contribution to journal › Review article › peer-review
Open Access28 Citations (Scopus) -
O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR
Tajadura-Ortega, V., Gambardella, G., Skinner, A., Halim, A., Van Coillie, J., Schjoldager, K. T-B. G., Beatson, R., Graham, R., Achkova, D., Taylor-Papadimitriou, J., Ciccarelli, F. D. & Burchell, J. M., 8 Aug 2020, (E-pub ahead of print) In: Glycobiology.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
2018
Glyco-immuno-oncology – Is it Time to Get Excited?
Beatson, R., 19 Mar 2018, In: Journal of Oncopathology and Clinical Research. 2, 1, p. 1-5 5 p., Vol 2 1:1.Research output: Contribution to journal › Article
Open AccessFile6265 Downloads (Pure) -
Latest developments in MUC1 immunotherapy
Taylor-Papadimitriou, J., Burchell, J. M., Graham, R. & Beatson, R., 2018, In: Biochemical Society Transactions. 46, 3, p. 659-668Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
O-linked mucin-type glycosylation in breast cancer
Burchell, J. M., Beatson, R., Graham, R., Taylor-Papadimitriou, J. & Tajadura-Ortega, V., Aug 2018, In: Biochemical Society Transactions. 46, 4, p. 779-788 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile71 Citations (Scopus)335 Downloads (Pure) -
2017
Interactions between the breast cancerassociated MUC1 mucins and C-type lectin characterized by optical tweezers
Hadjialirezaei, S., Picco, G., Beatson, R., Burchell, J., Stokke, B. T. & Sletmoen, M., 1 Apr 2017, In: PL o S One . 12, 4, e0175323.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
2016
The mucin MUC1 modulates the tumor immune microenvironment through the engagement of Siglec-9
Beatson, R., Tajadura-Ortega, V., Achkova, D. Y., Picco, G., Tsourouktsoglou, T-D., Klausing, S., Hillier, M., Maher, J., Noll, T., Crocker, P., Taylor-Papadimitriou, J. & Burchell, J., 1 Nov 2016, In: Nature Immunology. 17, 11, p. 1273-1281Research output: Contribution to journal › Article › peer-review
Open AccessFile253 Citations (Scopus)1287 Downloads (Pure) -
2015
The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL
Beatson, R., Maurstud, G., Picco, G., Arulappu, A., Coleman, J. A., Wandell, H. H., Clausen, H., Mandel, U., Taylor-Papadimitriou, J., Sletmoen, M. & Burchell, J. M., 7 May 2015, In: PLOS One. 10, 5, p. 1-21 21 p., e0125994.Research output: Contribution to journal › Article › peer-review
Open Access75 Citations (Scopus) -
2014
Adoptive Immunotherapy of Epithelial Ovarian Cancer with Vγ9Vδ2 T Cells, Potentiated by Liposomal Alendronic Acid
Parente-Pereira, A. C., Shmeeda, H., Whilding, L. M., Zambirinis, C. P., Foster, J., Van Der Stegen, S. J. C., Beatson, R., Zabinski, T., Brewig, N., Sosabowski, J. K., Mather, S., Ghaem-Maghami, S., Gabizon, A. & Maher, J., 1 Dec 2014, In: Journal of Immunology. 193, 11, p. 5557-5566 10 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas
Picco, F., Beatson, R., Taylor-Papadimitriou, J. & Burchell, J., Jul 2014, In: European Journal of Immunology. 44, 7, p. 1947-1955 9 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Citations (Scopus) -
2011
Expression of recombinant multi-coloured fluorescent antibodies in gor -/trxB- E. coli cytoplasm.
Markiv, A., Beatson, R., Burchell, J. M., Durvasula, R. V. & Kang, A. S., 30 Nov 2011, In: BMC BIOTECHNOLOGY. 11, 117, 10 p., 117.Research output: Contribution to journal › Article › peer-review
Open Access19 Citations (Scopus) -
PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells
Catchpole, S., Spencer-Dene, B., Hall, D., Santangelo, S., Rosewell, I., Guenatri, M., Beatson, R., Scibetta, A. G., Burchell, J. M. & Taylor-Papadimitriou, J., May 2011, In: International Journal of Oncology. 38, 5, p. 1267 - 1277 11 p.Research output: Contribution to journal › Article › peer-review
130 Citations (Scopus) -
Transforming growth factor-β1 is constitutively secreted by Chinese hamster ovary cells and is functional in human cells
Beatson, R., Sproviero, D., Maher, J., Wilkie, S., Taylor-Papadimitriou, J. & Burchell, J. M., Nov 2011, In: BIOTECHNOLOGY AND BIOENGINEERING. 108, 11, p. 2759-2764 6 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
2010
MUC1 Immunotherapy
Beatson, R., Burchell, J. & Taylor-Papadimitriou, J., May 2010, In: Immunotherapy. 2, 3, p. 305-327 23 p.Research output: Contribution to journal › Article › peer-review
121 Citations (Scopus) -
Over-expression of ST3Gal-I promotes mammary tumorigenesis
Picco, G., Julien, S., Brockhausen, I., Beatson, R., Antonopoulos, A., Haslam, S., Mandel, U., Dell, A., Pinder, S., Taylor-Papadimitriou, J. & Burchell, J., Oct 2010, In: Glycobiology. 20, 10, p. 1241 - 1250 10 p.Research output: Contribution to journal › Article › peer-review
116 Citations (Scopus)