King's College London

Research portal

Professor Richard Dobson

  1. Differential gene expression analysis in blood of first episode psychosis patients

    Leirer, D. J., Iyegbe, C. O., Di Forti, M., Patel, H., Carra, E., Fraietta, S., Colizzi, M., Mondelli, V., Quattrone, D., Lally, J., Ajnakina, O., Lee, S. H., Curtis, C. J., Breen, G., Pariante, C., Aitchison, K., Dazzan, P., Murray, R. M., Dobson, R. J. B. & Newhouse, S. J., 1 Jul 2019, In : Schizophrenia Research. 209, p. 88-97 10 p.

    Research output: Contribution to journalArticle

  2. Accepted/In press

    Challenges and solutions in a hybrid mHealth mobile application

    Ranjan, Y., Folarin, A., Stewart, C. L., Conde, M. P. G., Dobson, R. J. B. & Rashid, Z., Jul 2019, (Accepted/In press) UbiComp/ISWC ’19 Adjunct. ACM, 4 p. (Adjunct Proceedings of the 2019 ACM International Joint Conference on Pervasive and Ubiquitous Computing and the 2019 International Symposium on Wearable Computers (UbiComp/ISWC ’19 Adjunct)).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  3. A Meta-Analysis of Alzheimer’s Disease Brain Transcriptomic Data

    Patel, H., Dobson, R. J. B. & Newhouse, S. J., 23 Apr 2019, In : Journal of Alzheimer's Disease. 68, 4, p. 1635-1656 22 p.

    Research output: Contribution to journalArticle

  4. Telomere length is greater in ALS than in controls: A whole genome sequencing study

    Al Khleifat, A., Iacoangeli, A., Shatunov, A., Fang, T., Sproviero, W., Jones, A. R., Opie-Martin, S., Morrison, K. E., Shaw, P. J., Shaw, C. E. D., Powell, J. F., Dobson, R. J. B., Newhouse, S. & Al-Chalabi, A., 3 Apr 2019, In : Amyotrophic lateral sclerosis & frontotemporal degeneration. 20, 3-4, p. 229-234 6 p., IAFD 1586951.

    Research output: Contribution to journalArticle

  5. Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

    Jansen, I. E., Savage, J. E., Watanabe, K., Bryois, J., Williams, D. M., Steinberg, S., Sealock, J., Karlsson, I. K., Hägg, S., Athanasiu, L., Voyle, N., Proitsi, P., Witoelar, A., Stringer, S., Aarsland, D., Almdahl, I. S., Andersen, F., Bergh, S., Bettella, F., Bjornsson, S. & 33 othersBrækhus, A., Bråthen, G., de Leeuw, C., Desikan, R. S., Djurovic, S., Dumitrescu, L., Fladby, T., Hohman, T. J., Jonsson, P. V., Kiddle, S. J., Rongve, A., Saltvedt, I., Sando, S. B., Selbæk, G., Shoai, M., Skene, N. G., Snaedal, J., Stordal, E., Ulstein, I. D., Wang, Y., White, L. R., Hardy, J., Hjerling-Leffler, J., Sullivan, P. F., van der Flier, W. M., Dobson, R., Davis, L. K., Stefansson, H., Stefansson, K., Pedersen, N. L., Ripke, S., Andreassen, O. A. & Posthuma, D., 1 Mar 2019, In : Nature Genetics. 51, 3, p. 404-413 10 p.

    Research output: Contribution to journalArticle

  6. Accepted/In press

    Remote Assessment of Disease and Relapse in Major Depressive Disorder (RADAR-MDD): A multi-centre prospective cohort study protocol

    The RADAR-CNS consortium11, Matcham, F., Barattieri di San Pietro, C., Bulgari, V., de Girolamo, G., Dobson, R. J. B., Eriksson, H., Folarin, A., Haro, J. M., Kerz, M., Lamers, F., Li, Q., Manyakov, N., C. Mohr, D., Myin-Germeys, I., Narayan, V., Penninx, B. WJH., Ranjan, Y., Rashid, Z., Rintala, A. & 4 othersSiddi, S., Simblett, S. K., Wykes, T. HM. & Hotopf, M., 1 Feb 2019, (Accepted/In press) In : BMC Psychiatry.

    Research output: Contribution to journalArticle

  7. Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain

    Carbajosa, G., Malki, K., Lawless, N., Wang, H., Ryder, J. W., Wozniak, E., Wood, K., Mein, C. A., Dobson, R. J. B., Collier, D. A., O'Neill, M. J., Hodges, A. K. & Newhouse, S. J., 1 Sep 2018, In : Neurobiology of Aging. 69, p. 151-166 16 p.

    Research output: Contribution to journalArticle

  8. Loss of Trem2 in microglia leads to widespread disruption of cell co-expression networks in mouse brain

    Carbajosa, G., Malki, K., Lawless, N., Wang, H., Ryder, J. W., Wozniak, E., Mein, C. A., Dobson, R. J. B., Collier, D. A., O'Neill, M. J., Hodges, A. K. & Newhouse, S. J., Sep 2018, In : Neurobiology of Aging. 69, p. 151-166

    Research output: Contribution to journalArticle

  9. The EMIF-AD Multimodal Biomarker Discovery study: Design, methods and cohort characteristics

    Bos, I., Vos, S., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Baird, A., Dobson, R., Legido-Quigley, C., Sleegers, K., Van Broeckhoven, C., Bertram, L., Ten Kate, M., Barkhof, F., Zetterberg, H. & 3 othersLovestone, S., Streffer, J. & Visser, P. J., 6 Jul 2018, In : Alzheimer's Research and Therapy. 10, 1, 64.

    Research output: Contribution to journalArticle

  10. CogStack: Experiences of deploying integrated information retrieval and extraction services in a large National Health Service Foundation Trust hospital

    Jackson, R., Kartoglu, I., Stringer, C., Gorrell, G., Roberts, A., Song, X., Wu, H., Agrawal, A., Lui, K., Groza, T., Lewsley, D., Northwood, D., Folarin, A., Stewart, R. & Dobson, R., 25 Jun 2018, In : BMC medical informatics and decision making. 18, 1, 13 p.

    Research output: Contribution to journalArticle

  11. A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication

    Shi, L., Baird, A. L., Westwood, S., Hye, A., Dobson, R., Thambisetty, M. & Lovestone, S., 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 1181-1198 18 p.

    Research output: Contribution to journalReview article

  12. RADAR-base: Major Depressive Disorder and Epilepsy Case Studies

    Stewart, C. L., Rashid, Z., Ranjan, Y., Sun, S., Dobson, R. J. B. & Folarin, A. A., 2018, Proceedings of the 2018 ACM International Joint Conference and 2018 International Symposium on Pervasive and Ubiquitous Computing and Wearable Computers. New York, NY, USA: ACM, p. 1735-1743 9 p. (UbiComp '18).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  13. RADAR-base: A Novel Open Source m-Health Platform

    Ranjan, Y., Kerz, M., Rashid, Z., Böttcher, S., Dobson, R. J. B. & Folarin, A. A., 2018, Proceedings of the 2018 ACM International Joint Conference and 2018 International Symposium on Pervasive and Ubiquitous Computing and Wearable Computers. New York, NY, USA: ACM, p. 223-226 4 p. (UbiComp '18).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  14. ADEPt, a semantically-enriched pipeline for extracting adverse drug events from free-text electronic health records

    Iqbal, E., Mallah, R., Rhodes, D., Wu, H., Romero, A., Chang, N., Dzahini, O., Pandey, C., Broadbent, M., Stewart, R., Dobson, R. J. B., Ibrahim, Z. M. & Groza, T. (ed.), 9 Nov 2017, In : PL o S One . 12, 11, p. e0187121

    Research output: Contribution to journalArticle

  15. Network analysis of patient flow in two UK acute care hospitals identifies key sub-networks for A&E performance

    Bean, D. M., Stringer, C., Beeknoo, N., Teo, J. & Dobson, R. J. B., 2 Oct 2017, In : PLOS One.

    Research output: Contribution to journalArticle

  16. Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort

    Baker, E., Iqbal, E., Johnston, C., Broadbent, M., Shetty, H., Stewart, R., Howard, R., Newhouse, S., Khondoker, M. & Dobson, R. J. B., 7 Jun 2017, In : PLOS One. 12, 6, e0178562.

    Research output: Contribution to journalArticle

  17. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  18. Characterisation of mental health conditions in social media using Informed Deep Learning

    Gkotsis, G., Oellrich, A., Velupillai, S., Liakata, M., Hubbard, T. J. P., Dobson, R. J. B. & Dutta, R., 22 Mar 2017, In : Scientific Reports. 7, 45141.

    Research output: Contribution to journalArticle

  19. Brain transcriptome sequencing of a natural model of alzheimer's disease

    Altimiras, F., Uszczynska-Ratajczak, B., Camara, F., Vlasova, A., Palumbo, E., Newhouse, S., Deacon, R. M. J., Farias, L. A. E., Hurley, M. J., Loyola, D. E., Vásquez, R. A., Dobson, R., Guigó, R. & Cogram, P., 20 Mar 2017, In : Frontiers in Aging Neuroscience. 9, 64.

    Research output: Contribution to journalArticle

  20. Analysis of diagnoses extracted from Electronic health records in a large mental health Case Register

    Kovalchuk, Y., Stewart, R., Broadbent, M., Hubbard, T. J. P. & Dobson, R. J. B., 16 Feb 2017, In : PL o S One . 12, 2, p. e0171526 e0171526.

    Research output: Contribution to journalArticle

  21. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Proitsi, P., Kim, M., Whiley, L., Simmons, A., Sattlecker, M., Velayudhan, L., Lupton, M. K., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C., Feb 2017, In : Alzheimer's & Dementia. 13, 2, p. 140-151 12 p.

    Research output: Contribution to journalArticle

  22. Learning patient similarity using joint distributed embeddings of treatment and diagnoses

    Ormandy, C., Ibrahim, Z. M. & Dobson, R. J. B., 2017, In : CEUR Workshop Proceedings. 1891, p. 30-35 6 p.

    Research output: Contribution to journalArticle

  23. Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid

    Voyle, N., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B. & Kiddle, S. J., 20 Dec 2016, In : JOURNAL OF ALZHEIMERS DISEASE. 55, 4, p. 1417-1427

    Research output: Contribution to journalArticle

  24. Challenges and opportunities for system biology standards and tools in medical research

    König, M., Oellrich, A., Waltemath, D., Dobson, R. J. B., Hubbard, T. J. P. & Wolkenhauer, O., 29 Sep 2016, Proceedings of the 7th Workshop on Ontologies and Data in Life Sciences, organized by the GI Workgroup Ontologies in Biomedicine and Life Sciences. CEUR-WS, Vol. 1692.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  25. Accepted/In press

    Genetic risk as a marker of amyloid-beta and tau in cerebrospinal fluid

    Voyle, N. J., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B., Kiddle, S. J. & EDAR and DESCRIPA, 29 Sep 2016, (Accepted/In press) In : JOURNAL OF ALZHEIMERS DISEASE.

    Research output: Contribution to journalArticle

  26. SleepSight: A wearables-based relapse prevention system for Schizophrenia

    Kerz, M., Folarin, A., Meyer, N., Begale, M., MacCabe, J. & Dobson, R. J., 12 Sep 2016, UbiComp 2016 Adjunct - Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing. Association for Computing Machinery, Inc, p. 113-116 4 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  27. Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease

    Hakobyan, S., Harding, K., Aiyaz, M., Hye, A., Dobson, R., Baird, A., Liu, B., Harris, C. L., Lovestone, S. & Morgan, B. P., 6 Sep 2016, In : JOURNAL OF ALZHEIMERS DISEASE. 54, 2, p. 707-716 10 p.

    Research output: Contribution to journalArticle

  28. Accepted/In press

    Encoding Medication Episodes for Adverse Drug Event Prediction

    Wu, H., Ibrahim, Z., Iqbal, E. & Dobson, R. J. B., 9 Jul 2016, (Accepted/In press) The Thirty-Sixth Annual International Conference of the British Computer Society's Specialist Group on Artificial Intelligence .

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  29. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

    Fogh, I., Lin, K., Tiloca, C., Rooney, J., Gellera, C., Diekstra, F. P., Ratti, A., Shatunov, A., Van Es, M. A., Proitsi, P., Jones, A., Sproviero, W., Chiò, A., McLaughlin, R. L., Sorarù, G., Corrado, L., Stahl, D., Del Bo, R., Cereda, C., Castellotti, B. & 29 othersGlass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J., 1 Jul 2016, In : JAMA Neurology. 73, 7, p. 812-820 9 p.

    Research output: Contribution to journalArticle

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