King's College London

Research portal

Professor Richard Dobson

  1. Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort

    Baker, E., Iqbal, E., Johnston, C., Broadbent, M., Shetty, H., Stewart, R., Howard, R., Newhouse, S., Khondoker, M. & Dobson, R. J. B. 7 Jun 2017 In : PLOS One. 12, 6

    Research output: Contribution to journalArticle

  2. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A. 1 May 2017 In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  3. Characterisation of mental health conditions in social media using Informed Deep Learning

    Gkotsis, G., Oellrich, A., Velupillai, S., Liakata, M., Hubbard, T. J. P., Dobson, R. J. B. & Dutta, R. 22 Mar 2017 In : Scientific Reports. 7, 45141

    Research output: Contribution to journalArticle

  4. Brain transcriptome sequencing of a natural model of alzheimer's disease

    Altimiras, F., Uszczynska-Ratajczak, B., Camara, F., Vlasova, A., Palumbo, E., Newhouse, S., Deacon, R. M. J., Farias, L. A. E., Hurley, M. J., Loyola, D. E., Vásquez, R. A., Dobson, R., Guigó, R. & Cogram, P. 20 Mar 2017 In : Frontiers in aging neuroscience. 9, MAR, 64

    Research output: Contribution to journalArticle

  5. Analysis of diagnoses extracted from Electronic health records in a large mental health Case Register

    Kovalchuk, Y., Stewart, R., Broadbent, M., Hubbard, T. J. P. & Dobson, R. J. B. 16 Feb 2017 In : PL o S One . 12, 2, p. e0171526 e0171526

    Research output: Contribution to journalArticle

  6. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Proitsi, P., Kim, M., Whiley, L., Simmons, A., Sattlecker, M., Velayudhan, L., Lupton, M. K., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C. Feb 2017 In : Alzheimer's & Dementia. 13, 2, p. 140-151 12 p.

    Research output: Contribution to journalArticle

  7. Genetic Risk as a Marker of Amyloid-beta and Tau Burden in Cerebrospinal Fluid

    Voyle, N., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B. & Kiddle, S. J. 2017 In : JOURNAL OF ALZHEIMERS DISEASE. 55, 4, p. 1417-1427

    Research output: Contribution to journalArticle

  8. Accepted/In press
  9. Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid

    Voyle, N., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B., Kiddle, S. J. & EDAR and DESCRIPA study groups and the Alzheimer’s Disease Neuroimaging Initiative 6 Nov 2016 In : JOURNAL OF ALZHEIMERS DISEASE.

    Research output: Contribution to journalArticle

  10. Challenges and opportunities for system biology standards and tools in medical research

    König, M., Oellrich, A., Waltemath, D., Dobson, R. J. B., Hubbard, T. J. P. & Wolkenhauer, O. 29 Sep 2016 Proceedings of the 7th Workshop on Ontologies and Data in Life Sciences, organized by the GI Workgroup Ontologies in Biomedicine and Life Sciences. CEUR-WS, Vol. 1692

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  11. Accepted/In press

    Genetic risk as a marker of amyloid-beta and tau in cerebrospinal fluid

    Voyle, N. J., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B., Kiddle, S. J. & EDAR and DESCRIPA 29 Sep 2016 In : JOURNAL OF ALZHEIMERS DISEASE.

    Research output: Contribution to journalArticle

  12. SleepSight: A wearables-based relapse prevention system for Schizophrenia

    Kerz, M., Folarin, A., Meyer, N., Begale, M., MacCabe, J. & Dobson, R. J. 12 Sep 2016 UbiComp 2016 Adjunct - Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing. Association for Computing Machinery, Inc, p. 113-116 4 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  13. Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease

    Hakobyan, S., Harding, K., Aiyaz, M., Hye, A., Dobson, R., Baird, A., Liu, B., Harris, C. L., Lovestone, S. & Morgan, B. P. 6 Sep 2016 In : JOURNAL OF ALZHEIMERS DISEASE. 54, 2, p. 707-716 10 p.

    Research output: Contribution to journalArticle

  14. Accepted/In press

    Encoding Medication Episodes for Adverse Drug Event Prediction

    Wu, H., Ibrahim, Z., Iqbal, E. & Dobson, R. J. B. 9 Jul 2016 The Thirty-Sixth Annual International Conference of the British Computer Society's Specialist Group on Artificial Intelligence .

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  15. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

    Fogh, I. , Lin, K. , Tiloca, C. , Rooney, J. , Gellera, C. , Diekstra, F. P. , Ratti, A. , Shatunov, A. , Van Es, M. A. , Proitsi, P. , Jones, A. , Sproviero, W. , Chiò, A. , McLaughlin, R. L. , Sorarù, G. , Corrado, L. , Stahl, D. , Del Bo, R. , Cereda, C. , Castellotti, B. & 29 others Glass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J. 1 Jul 2016 In : JAMA Neurology. 73, 7, p. 812-820 9 p.

    Research output: Contribution to journalArticle

  16. Combining clinical variables to optimize prediction of antidepressant treatment outcomes

    Iniesta, R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovsek, M. Z., Souery, D., Stahl, D., Dobson, R., Aitchison, K. J., Farmer, A., Lewis, C. M., McGuffin, P. & Uher, R. Jul 2016 In : Journal of psychiatric research. 78, p. 94-102 9 p.

    Research output: Contribution to journalArticle

  17. The language of mental health problems in social media

    Gkotsis, G., Oellrich, A., Hubbard, T. J. P., Dobson, R. J. B., Liakata, M., Velupillai, S. & Dutta, R. 16 Jun 2016 The Third Computational Linguistics and Clinical Psychology Workshop (CLPsych). p. 63-73

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  18. Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

    Allen, G. I. , Amoroso, N. , Anghel, C. , Balagurusamy, V. , Bare, C. J. , Beaton, D. , Bellotti, R. , Bennett, D. A. , Boehme, K. L. , Boutros, P. C. , Caberlotto, L. , Caloian, C. , Campbell, F. , Chaibub Neto, E. , Chang, Y. C. , Chen, B. , Chen, C. Y. , Chien, T. Y. , Clark, T. , Das, S. & 81 others Davatzikos, C., Deng, J., Dillenberger, D., Dobson, R. J. B., Dong, Q., Doshi, J., Duma, D., Errico, R., Erus, G., Everett, E., Fardo, D. W., Friend, S. H., Fröhlich, H., Gan, J., St George-Hyslop, P., Ghosh, S. S., Glaab, E., Green, R. C., Guan, Y., Hong, M. Y., Huang, C., Hwang, J., Ibrahim, J., Inglese, P., Iyappan, A., Jiang, Q., Katsumata, Y., Kauwe, J. S. K., Klein, A., Kong, D., Krause, R., Lalonde, E., Lauria, M., Lee, E., Lin, X., Liu, Z., Livingstone, J., Logsdon, B. A., Lovestone, S., Ma, T. W., Malhotra, A., Mangravite, L. M., Maxwell, T. J., Merrill, E., Nagorski, J., Namasivayam, A., Narayan, M., Naz, M., Newhouse, S. J., Norman, T. C., Nurtdinov, R. N., Oyang, Y. J., Pawitan, Y., Peng, S., Peters, M. A., Piccolo, S. R., Praveen, P., Priami, C., Sabelnykova, V. Y., Senger, P., Shen, X., Simmons, A., Sotiras, A., Stolovitzky, G., Tangaro, S., Tateo, A., Tung, Y. A., Tustison, N. J., Varol, E., Vradenburg, G., Weiner, M. W., Xiao, G., Xie, L., Xie, Y., Xu, J., Yang, H., Zhan, X., Zhou, Y., Zhu, F., Zhu, H. & Zhu, S. 11 Apr 2016 In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  19. Transcriptomics and the mechanisms of antidepressant efficacy

    Hodgson, K., Tansey, K. E., Powell, T., Coppola, G., Uher, R., Zvezdana Dernovšek, M., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Aitchison, K. J., Craig, I. W., Farmer, A. E., Breen, G., Mcguffin, P. & Dobson, R. 1 Jan 2016 In : European Neuropsychopharmacology. 26, 1, p. 105-112 8 p.

    Research output: Contribution to journalArticle

  20. A pathway based classification method for analyzing gene expression for Alzheimer's disease diagnosis

    Voyle, N., Keohane, A., Newhouse, S., Lunnon, K., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Hodges, A., Kiddle, S. & Dobson, R. J. B. 2016 In : JOURNAL OF ALZHEIMERS DISEASE. 49, 3, p. 659-669 11 p.

    Research output: Contribution to journalArticle

  21. Microduplications at the pseudoautosomal SHOX locus in autism spectrum disorders and related neurodevelopmental conditions

    Tropeano, M. , Howley, D. , Gazzellone, M. J. , Wilson, C. E. , Ahn, J. W. , Stavropoulos, D. J. , Murphy, C. , Eis, P. S. , Hatchwell, E. , Dobson, R. J. B. , Robertson, D. , Holder, M. , Irving, M. , Josifova, D. , Nehammer, A. , Ryten, M. , Spain, D. , Pitts, M. , Bramham, J. , Asherson, P. & 9 others Curran, S., Vassos, E., Breen, G., Flinter, F., Ogilvie, C. M., Collier, D. A., Scherer, S. W., Mcalonan, G. M. & Murphy, D. G. 2016 In : Journal of Medical Genetics.

    Research output: Contribution to journalArticle

  22. Longitudinal Protein Changes in Blood Plasma Associated with the Rate of Cognitive Decline in Alzheimer's Disease

    Sattlecker, M., Khondoker, M., Proitsi, P., Williams, S., Soininen, H., K??oszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S. & Dobson, R. J. 23 Nov 2015 In : JOURNAL OF ALZHEIMERS DISEASE. 49, 4, p. 1105-1114

    Research output: Contribution to journalArticle

  23. Microdeletions of ELP4 are Associated with Language Impairment, Autism Spectrum Disorder and Mental Retardation

    Addis, L. , Ahn, J. W. , Dobson, R. J. B. , Dixit, A. , Ogilvie, C. M. , Pinto, D. , Vaags, A. K. , Coon, H. , Chaste, P. , Wilson, S. , Parr, J. R. , Andrieux, J. , Lenne, B. , Tumer, Z. , Leuzzi, V. , Aubell, K. , Koillinen, H. , Curran, S. R. , Marshall, C. R. , Scherer, S. W. & 3 others Strug, L. J., Collier, D. A. & Pal, D. K. 1 Sep 2015 In : Human Mutation. 36, 9

    Research output: Contribution to journalArticle

  24. A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease

    Khan, W., Aguilar, C., Kiddle, S. J., Doyle, O., Thambisetty, M., Muehlboeck, S., Sattlecker, M., Newhouse, S., Lovestone, S., Dobson, R., Giampietro, V., Westman, E., Simmons, A. & Alzheimer’s Disease Neuroimaging Initiative 18 Aug 2015 In : PloS one. 10, 8, 16 p., e0134368

    Research output: Contribution to journalArticle

  25. Tract based spatial statistic reveals no differences in white matter microstructural organization between carriers and non-carriers of the APOE ε4 and ε2 alleles in young healthy adolescents

    Dell'Acqua, F. , Khan, W. , Gottlieb, N. , Giampietro, V. , Ginestet, C. , Bouls, D. , Newhouse, S. , Dobson, R. , Banaschewski, T. , Barker, G. J. , Bokde, A. L. W. , Büchel, C. , Conrod, P. , Flor, H. , Frouin, V. , Garavan, H. , Gowland, P. , Heinz, A. , Lemaítre, H. , Nees, F. & 10 others Paus, T., Pausova, Z., Rietschel, M., Smolka, M. N., Ströhle, A., Gallinat, J., Westman, E., Schumann, G., Lovestone, S. & Simmons, A. 11 Aug 2015 In : JOURNAL OF ALZHEIMERS DISEASE. 47, 4, p. 977-984 8 p.

    Research output: Contribution to journalArticle

  26. No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease

    Chiam, J. T. W., Lunnon, K., Voyle, N., Proitsi, P., Coppola, G., Geschwind, D., Nelson, S., Johnston, C., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolakik, M., Vellas, B., Hodges, A., Lovestone, S., Newhouse, S., Dobson, R. J. B., Kiddle, S. J. & Sattlecker, M. 3 Aug 2015 In : JOURNAL OF ALZHEIMERS DISEASE. 47, 3, p. 741-750 10 p.

    Research output: Contribution to journalArticle

  27. Exploring the role of drug-metabolising enzymes in antidepressant side effects

    Hodgson, K., Tansey, K. E., Uher, R., Dernovšek, M. Z., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Craig, I. W., Aitchison, K. J., Farmer, A., Dobson, R. J. B. & McGuffin, P. Jul 2015 In : Psychopharmacology. 232, 14, p. 2609-2617 9 p.

    Research output: Contribution to journalArticle

  28. Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology.

    Voyle, N., Baker, D., Burnham, S. C., Covin, A., Zhang, Z., Sangurdekar, D. P., Tan, H. C. A., Bazenet, C., Lovestone, S., Kiddle, S. & Dobson, R. J. B. 26 Jun 2015 In : JOURNAL OF ALZHEIMERS DISEASE. 46, 4, p. 947-961 15 p.

    Research output: Contribution to journalArticle

  29. Plasma protein biomarkers of Alzheimer’s disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes

    Kiddle, S. J. , Steves, C. J. , Mehta, M. , Simmons, A. , Xu, X. , Newhouse, S. , Sattlecker, M. , Ashton, N. , Bazenet, C. , Killick, R. , Adnan, J. , Westman, E. , Nelson, S. , Soininen, H. , Kloszewska, I. , Mecocci, P. , Tsolaki, M. , Vellas, B. , Curtis, C. , Breen, G. & 4 others Williams, S. C. R., Lovestone, S., Spector, T. D. & Dobson, R. J. B. 16 Jun 2015 In : Translational psychiatry. 5, 6, 6 p., e584

    Research output: Contribution to journalArticle

  30. A Multi-Agent Platform for Automating the Collection of Patient-Provided Clinical Feedback

    Ibrahim, Z., Fernandez de la Cruz, L., Stringaris, A., Goodman, R., Luck, M. & Dobson, R. May 2015 Proceedings of the International Conference on Autonomous Agents and Multiagent Systems. International Foundation for Autonomous Agents and Multiagent Systems (IFAAMAS), Vol. 2, p. 831-839 9 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  31. Blood protein predictors of brain amyloid for enrichment in clinical trials?

    Ashton, N., Kiddle, S., Graf, J., Ward, M., Baird, A., Hye, A., Westwood, S., Wong, K. V., Dobson, R., Rabinovici, G., Miller, B., Rosen, H., Torres, A., Zhang, Z., Thurfjell, L., Covin, A., Hehir, C., Baker, D., Bazenet, C. & Lovestone, S. 29 Mar 2015 In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 1, p. 48-60 13 p.

    Research output: Contribution to journalArticle

  32. Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease

    Proitsi, P., Kim, M., Whiley, L., Pritchard, M., Leung, R., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Sham, P., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C. 13 Jan 2015 In : Translational psychiatry. 5, 8 p., e494

    Research output: Contribution to journalArticle

  33. Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts

    Khondoker, M., Newhouse, S., Westman, E., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Dobson, R. & Simmons, A. 2015 In : Journal of Alzheimer's disease : JAD. 45, 3, p. 851-864 14 p.

    Research output: Contribution to journalArticle

  34. Accepted/In press

    Microdeletions of ELP4 are associated with language impairment, autism spectrum disorder and epilepsy

    Pal, D. , Addis, L. , Ahn, J. W. , Dobson, R. , Dixit, A. , Ogilvie, C. , Pinto, D. , Vaags, A. K. , Coon, H. , Chaste, P. , Wilson, S. , Parr, J. R. , Andrieux, J. , lenne, B. , turner, Z. , leuzzi, V. , aubell, K. , koillinen, H. , Curran, S. , Marshall, C. R. & 2 others Scherer, S. W. & Strug, L. J. 2015 In : Human Mutation.

    Research output: Contribution to journalArticle

  35. Accepted/In press

    Tract Based Spatial Statistic reveals no differences in white matter microstructural organisation between carriers and non-carriers of the ApoE ε4 and ε2 alleles in young healthy adolescents

    Dell' Acqua, F. , Khan, W. N. , Gottlieb, N. N. , Giampietro, V. P. , Ginestet, C. E. , Bouls, D. T. T. , Newhouse, S. , Dobson, R. , Banaschewski, T. , Barker, G. J. , Bokde, A. L. W. , Buechel, C. , Conrod, P. , Flor, H. , Frouin, V. , Garavan, H. , Gowland, P. , Heinz, A. , Lemaître, H. , Nees, F. & 10 others Paus, T., Pausova, Z., Rietschel, M., Smolka, M. N., Stroehle, A., Gallinat, J., Westrnan, E., Schumann, G., Lovestone, S. & Simmons, A. 2015 In : Journal of Alzheimer's Disease.

    Research output: Contribution to journalArticle

  36. Remote monitoring of sleep-wake activity as an early warning sign in psychosis: a novel, exploratory approach

    Meyer, N., Folarin, A., Dobson, R. & MacCabe, J. 11 Nov 2014 Early Intervention in Psychiatry: Special Issue: 9TH International Conference on Early Psychosis – To the New Horizon, 17 November 2014, Tokyo Japan. Vol. 8, p. 100-100 1 p. B13

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  37. Plasma proteins predict conversion to dementia from prodromal disease

    Hye, A. , Riddoch-Contreras, J. , Baird, A. L. , Ashton, N. , Bazenet, C. , Leung, R. , Westman, E. , Simmons, A. , Dobson, R. , Sattlecker, M. , Lupton, M. , Lunnon, K. , Keohane, A. , Ward, M. , Pike, I. , Zucht, H. D. , Pepin, D. , Zheng, W. , Tunnicliffe, A. , Richardson, J. & 7 others Gauthier, S., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B. & Lovestone, S. 1 Nov 2014 In : Alzheimer's & dementia : the journal of the Alzheimer's Association. 10, 6, p. 799–807.e2 11 p.

    Research output: Contribution to journalArticle

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