King's College London

Research portal

Professor Richard Dobson

  1. Remote assessment of disease and relapse in major depressive disorder (RADAR-MDD): A multi-centre prospective cohort study protocol 11 Medical and Health Sciences 1103 Clinical Sciences 11 Medical and Health Sciences 1117 Public Health and Health Services

    Matcham, F., Barattieri Di San Pietro, C., Bulgari, V., De Girolamo, G., Dobson, R., Eriksson, H., Folarin, A. A., Haro, J. M., Kerz, M., Lamers, F., Li, Q., Manyakov, N. V., Mohr, D. C., Myin-Germeys, I., Narayan, V., Bwjh, P., Ranjan, Y., Rashid, Z., Rintala, A., Siddi, S. & 16 othersSimblett, S. K., Wykes, T., Hotopf, M., Difrancesco, S., White, K., Ivan, A., Polhemus, A., Ferrao, J., Ringkjøbing-Elema, M., Nobilia, F., Viechtbauer, W., Peelen, S., Rashid, Z., Boere, J., Cummins, N. & Meyer, N., 18 Feb 2019, In : BMC Psychiatry. 19, 1, 72.

    Research output: Contribution to journalReview article

  2. Accepted/In press

    Remote Assessment of Disease and Relapse in Major Depressive Disorder (RADAR-MDD): A multi-centre prospective cohort study protocol

    The RADAR-CNS consortium11, Matcham, F., Barattieri di San Pietro, C., Bulgari, V., de Girolamo, G., Dobson, R. J. B., Eriksson, H., Folarin, A., Haro, J. M., Kerz, M., Lamers, F., Li, Q., Manyakov, N., C. Mohr, D., Myin-Germeys, I., Narayan, V., Penninx, B. WJH., Ranjan, Y., Rashid, Z., Rintala, A. & 4 othersSiddi, S., Simblett, S. K., Wykes, T. HM. & Hotopf, M., 1 Feb 2019, (Accepted/In press) In : BMC Psychiatry.

    Research output: Contribution to journalArticle

  3. Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

    Jansen, I. E., Savage, J. E., Watanabe, K., Bryois, J., Williams, D. M., Steinberg, S., Sealock, J., Karlsson, I. K., Hägg, S., Athanasiu, L., Voyle, N., Proitsi, P., Witoelar, A., Stringer, S., Aarsland, D., Almdahl, I. S., Andersen, F., Bergh, S., Bettella, F., Bjornsson, S. & 33 othersBrækhus, A., Bråthen, G., de Leeuw, C., Desikan, R. S., Djurovic, S., Dumitrescu, L., Fladby, T., Hohman, T. J., Jonsson, P. V., Kiddle, S. J., Rongve, A., Saltvedt, I., Sando, S. B., Selbæk, G., Shoai, M., Skene, N. G., Snaedal, J., Stordal, E., Ulstein, I. D., Wang, Y., White, L. R., Hardy, J., Hjerling-Leffler, J., Sullivan, P. F., van der Flier, W. M., Dobson, R., Davis, L. K., Stefansson, H., Stefansson, K., Pedersen, N. L., Ripke, S., Andreassen, O. A. & Posthuma, D., 7 Jan 2019, In : Nature Genetics.

    Research output: Contribution to journalArticle

  4. Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain

    Carbajosa, G., Malki, K., Lawless, N., Wang, H., Ryder, J. W., Wozniak, E., Wood, K., Mein, C. A., Dobson, R. J. B., Collier, D. A., O'Neill, M. J., Hodges, A. K. & Newhouse, S. J., 1 Sep 2018, In : Neurobiology of Aging. 69, p. 151-166 16 p.

    Research output: Contribution to journalArticle

  5. Loss of Trem2 in microglia leads to widespread disruption of cell co-expression networks in mouse brain

    Carbajosa, G., Malki, K., Lawless, N., Wang, H., Ryder, J. W., Wozniak, E., Mein, C. A., Dobson, R. J. B., Collier, D. A., O'Neill, M. J., Hodges, A. K. & Newhouse, S. J., Sep 2018, In : Neurobiology of Aging. 69, p. 151-166

    Research output: Contribution to journalArticle

  6. The EMIF-AD Multimodal Biomarker Discovery study: Design, methods and cohort characteristics

    Bos, I., Vos, S., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Baird, A., Dobson, R., Legido-Quigley, C., Sleegers, K., Van Broeckhoven, C., Bertram, L., Ten Kate, M., Barkhof, F., Zetterberg, H. & 3 othersLovestone, S., Streffer, J. & Visser, P. J., 6 Jul 2018, In : Alzheimer's Research and Therapy. 10, 1, 64.

    Research output: Contribution to journalArticle

  7. CogStack: Experiences of deploying integrated information retrieval and extraction services in a large National Health Service Foundation Trust hospital

    Jackson, R., Kartoglu, I., Stringer, C., Gorrell, G., Roberts, A., Song, X., Wu, H., Agrawal, A., Lui, K., Groza, T., Lewsley, D., Northwood, D., Folarin, A., Stewart, R. & Dobson, R., 25 Jun 2018, In : BMC medical informatics and decision making. 18, 1, 13 p.

    Research output: Contribution to journalArticle

  8. A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication

    Shi, L., Baird, A. L., Westwood, S., Hye, A., Dobson, R., Thambisetty, M. & Lovestone, S., 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 1181-1198 18 p.

    Research output: Contribution to journalReview article

  9. RADAR-base: Major Depressive Disorder and Epilepsy Case Studies

    Stewart, C. L., Rashid, Z., Ranjan, Y., Sun, S., Dobson, R. J. B. & Folarin, A. A., 2018, Proceedings of the 2018 ACM International Joint Conference and 2018 International Symposium on Pervasive and Ubiquitous Computing and Wearable Computers. New York, NY, USA: ACM, p. 1735-1743 9 p. (UbiComp '18).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  10. RADAR-base: A Novel Open Source m-Health Platform

    Ranjan, Y., Kerz, M., Rashid, Z., Böttcher, S., Dobson, R. J. B. & Folarin, A. A., 2018, Proceedings of the 2018 ACM International Joint Conference and 2018 International Symposium on Pervasive and Ubiquitous Computing and Wearable Computers. New York, NY, USA: ACM, p. 223-226 4 p. (UbiComp '18).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  11. ADEPt, a semantically-enriched pipeline for extracting adverse drug events from free-text electronic health records

    Iqbal, E., Mallah, R., Rhodes, D., Wu, H., Romero, A., Chang, N., Dzahini, O., Pandey, C., Broadbent, M., Stewart, R., Dobson, R. J. B., Ibrahim, Z. M. & Groza, T. (ed.), 9 Nov 2017, In : PL o S One . 12, 11, p. e0187121

    Research output: Contribution to journalArticle

  12. Network analysis of patient flow in two UK acute care hospitals identifies key sub-networks for A&E performance

    Bean, D. M., Stringer, C., Beeknoo, N., Teo, J. & Dobson, R. J. B., 2 Oct 2017, In : PLOS One.

    Research output: Contribution to journalArticle

  13. Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort

    Baker, E., Iqbal, E., Johnston, C., Broadbent, M., Shetty, H., Stewart, R., Howard, R., Newhouse, S., Khondoker, M. & Dobson, R. J. B., 7 Jun 2017, In : PLOS One. 12, 6, e0178562.

    Research output: Contribution to journalArticle

  14. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  15. Characterisation of mental health conditions in social media using Informed Deep Learning

    Gkotsis, G., Oellrich, A., Velupillai, S., Liakata, M., Hubbard, T. J. P., Dobson, R. J. B. & Dutta, R., 22 Mar 2017, In : Scientific Reports. 7, 45141.

    Research output: Contribution to journalArticle

  16. Brain transcriptome sequencing of a natural model of alzheimer's disease

    Altimiras, F., Uszczynska-Ratajczak, B., Camara, F., Vlasova, A., Palumbo, E., Newhouse, S., Deacon, R. M. J., Farias, L. A. E., Hurley, M. J., Loyola, D. E., Vásquez, R. A., Dobson, R., Guigó, R. & Cogram, P., 20 Mar 2017, In : Frontiers in Aging Neuroscience. 9, 64.

    Research output: Contribution to journalArticle

  17. Analysis of diagnoses extracted from Electronic health records in a large mental health Case Register

    Kovalchuk, Y., Stewart, R., Broadbent, M., Hubbard, T. J. P. & Dobson, R. J. B., 16 Feb 2017, In : PL o S One . 12, 2, p. e0171526 e0171526.

    Research output: Contribution to journalArticle

  18. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Proitsi, P., Kim, M., Whiley, L., Simmons, A., Sattlecker, M., Velayudhan, L., Lupton, M. K., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C., Feb 2017, In : Alzheimer's & Dementia. 13, 2, p. 140-151 12 p.

    Research output: Contribution to journalArticle

  19. Learning patient similarity using joint distributed embeddings of treatment and diagnoses

    Ormandy, C., Ibrahim, Z. M. & Dobson, R. J. B., 2017, In : CEUR Workshop Proceedings. 1891, p. 30-35 6 p.

    Research output: Contribution to journalArticle

  20. Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid

    Voyle, N., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B. & Kiddle, S. J., 20 Dec 2016, In : JOURNAL OF ALZHEIMERS DISEASE. 55, 4, p. 1417-1427

    Research output: Contribution to journalArticle

  21. Challenges and opportunities for system biology standards and tools in medical research

    König, M., Oellrich, A., Waltemath, D., Dobson, R. J. B., Hubbard, T. J. P. & Wolkenhauer, O., 29 Sep 2016, Proceedings of the 7th Workshop on Ontologies and Data in Life Sciences, organized by the GI Workgroup Ontologies in Biomedicine and Life Sciences. CEUR-WS, Vol. 1692.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  22. Accepted/In press

    Genetic risk as a marker of amyloid-beta and tau in cerebrospinal fluid

    Voyle, N. J., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B., Kiddle, S. J. & EDAR and DESCRIPA, 29 Sep 2016, (Accepted/In press) In : JOURNAL OF ALZHEIMERS DISEASE.

    Research output: Contribution to journalArticle

  23. SleepSight: A wearables-based relapse prevention system for Schizophrenia

    Kerz, M., Folarin, A., Meyer, N., Begale, M., MacCabe, J. & Dobson, R. J., 12 Sep 2016, UbiComp 2016 Adjunct - Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing. Association for Computing Machinery, Inc, p. 113-116 4 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  24. Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease

    Hakobyan, S., Harding, K., Aiyaz, M., Hye, A., Dobson, R., Baird, A., Liu, B., Harris, C. L., Lovestone, S. & Morgan, B. P., 6 Sep 2016, In : JOURNAL OF ALZHEIMERS DISEASE. 54, 2, p. 707-716 10 p.

    Research output: Contribution to journalArticle

  25. Accepted/In press

    Encoding Medication Episodes for Adverse Drug Event Prediction

    Wu, H., Ibrahim, Z., Iqbal, E. & Dobson, R. J. B., 9 Jul 2016, (Accepted/In press) The Thirty-Sixth Annual International Conference of the British Computer Society's Specialist Group on Artificial Intelligence .

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  26. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

    Fogh, I., Lin, K., Tiloca, C., Rooney, J., Gellera, C., Diekstra, F. P., Ratti, A., Shatunov, A., Van Es, M. A., Proitsi, P., Jones, A., Sproviero, W., Chiò, A., McLaughlin, R. L., Sorarù, G., Corrado, L., Stahl, D., Del Bo, R., Cereda, C., Castellotti, B. & 29 othersGlass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J., 1 Jul 2016, In : JAMA Neurology. 73, 7, p. 812-820 9 p.

    Research output: Contribution to journalArticle

  27. Combining clinical variables to optimize prediction of antidepressant treatment outcomes

    Iniesta, R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovsek, M. Z., Souery, D., Stahl, D., Dobson, R., Aitchison, K. J., Farmer, A., Lewis, C. M., McGuffin, P. & Uher, R., Jul 2016, In : Journal of psychiatric research. 78, p. 94-102 9 p.

    Research output: Contribution to journalArticle

  28. The language of mental health problems in social media

    Gkotsis, G., Oellrich, A., Hubbard, T., Dobson, R. JB., Liakata, M., Velupillai, S. & Dutta, R., 16 Jun 2016, The Third Computational Linguistics and Clinical Psychology Workshop (CLPsych). p. 63-73

    Research output: Chapter in Book/Report/Conference proceedingConference paper

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