King's College London

Research portal

Professor Richard Dobson

  1. Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain

    Carbajosa, G., Malki, K., Lawless, N., Wang, H., Ryder, J. W., Wozniak, E., Wood, K., Mein, C. A., Dobson, R. J. B., Collier, D. A., O'Neill, M. J., Hodges, A. K. & Newhouse, S. J. 1 Sep 2018 In : Neurobiology of Aging. 69, p. 151-166 16 p.

    Research output: Contribution to journalArticle

  2. Loss of Trem2 in microglia leads to widespread disruption of cell co-expression networks in mouse brain

    Carbajosa , G., Malki, K., Lawless, N., Wang, H., Ryder, J. W., Wozniak, E., Mein, C. A., Dobson, R. J. B., Collier, D. A., O'Neill, M. J., Hodges, A. K. & Newhouse, S. J. Sep 2018 In : Neurobiology of Aging. 69, p. 151-166

    Research output: Contribution to journalArticle

  3. The EMIF-AD Multimodal Biomarker Discovery study: Design, methods and cohort characteristics

    Bos, I. , Vos, S. , Vandenberghe, R. , Scheltens, P. , Engelborghs, S. , Frisoni, G. , Molinuevo, J. L. , Wallin, A. , Lleó, A. , Popp, J. , Martinez-Lage, P. , Baird, A. , Dobson, R. , Legido-Quigley, C. , Sleegers, K. , Van Broeckhoven, C. , Bertram, L. , Ten Kate, M. , Barkhof, F. , Zetterberg, H. & 3 others Lovestone, S., Streffer, J. & Visser, P. J. 6 Jul 2018 In : Alzheimer's Research and Therapy. 10, 1, 64

    Research output: Contribution to journalArticle

  4. CogStack: Experiences of deploying integrated information retrieval and extraction services in a large National Health Service Foundation Trust hospital

    Jackson, R., Kartoglu, I., Stringer, C., Gorrell, G., Roberts, A., Song, X., Wu, H., Agrawal, A., Lui, K., Groza, T., Lewsley, D., Northwood, D., Folarin, A., Stewart, R. & Dobson, R. 25 Jun 2018 In : BMC medical informatics and decision making. 18, 1, 13 p.

    Research output: Contribution to journalArticle

  5. A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication

    Shi, L., Baird, A. L., Westwood, S., Hye, A., Dobson, R., Thambisetty, M. & Lovestone, S. 2018 In : Journal of Alzheimer's Disease. 62, 3, p. 1181-1198 18 p.

    Research output: Contribution to journalReview article

  6. RADAR-base: Major Depressive Disorder and Epilepsy Case Studies

    Stewart, C. L., Rashid, Z., Ranjan, Y., Sun, S., Dobson, R. J. B. & Folarin, A. A. 2018 Proceedings of the 2018 ACM International Joint Conference and 2018 International Symposium on Pervasive and Ubiquitous Computing and Wearable Computers. New York, NY, USA: ACM, p. 1735-1743 9 p. (UbiComp '18)

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  7. RADAR-base: A Novel Open Source m-Health Platform

    Ranjan, Y., Kerz, M., Rashid, Z., Böttcher, S., Dobson, R. J. B. & Folarin, A. A. 2018 Proceedings of the 2018 ACM International Joint Conference and 2018 International Symposium on Pervasive and Ubiquitous Computing and Wearable Computers. New York, NY, USA: ACM, p. 223-226 4 p. (UbiComp '18)

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  8. ADEPt, a semantically-enriched pipeline for extracting adverse drug events from free-text electronic health records

    Iqbal, E., Mallah, R., Rhodes, D., Wu, H., Romero, A., Chang, N., Dzahini, O., Pandey, C., Broadbent, M., Stewart, R., Dobson, R. J. B., Ibrahim, Z. M. & Groza, T. (ed.) 9 Nov 2017 In : PL o S One . 12, 11, p. e0187121

    Research output: Contribution to journalArticle

  9. Network analysis of patient flow in two UK acute care hospitals identifies key sub-networks for A&E performance

    Bean, D. M., Stringer, C., Beeknoo, N., Teo, J. & Dobson, R. J. B. 2 Oct 2017 In : PLOS One.

    Research output: Contribution to journalArticle

  10. Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort

    Baker, E., Iqbal, E., Johnston, C., Broadbent, M., Shetty, H., Stewart, R., Howard, R., Newhouse, S., Khondoker, M. & Dobson, R. J. B. 7 Jun 2017 In : PLOS One. 12, 6, e0178562

    Research output: Contribution to journalArticle

  11. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A. 1 May 2017 In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  12. Characterisation of mental health conditions in social media using Informed Deep Learning

    Gkotsis, G., Oellrich, A., Velupillai, S., Liakata, M., Hubbard, T. J. P., Dobson, R. J. B. & Dutta, R. 22 Mar 2017 In : Scientific Reports. 7, 45141

    Research output: Contribution to journalArticle

  13. Brain transcriptome sequencing of a natural model of alzheimer's disease

    Altimiras, F., Uszczynska-Ratajczak, B., Camara, F., Vlasova, A., Palumbo, E., Newhouse, S., Deacon, R. M. J., Farias, L. A. E., Hurley, M. J., Loyola, D. E., Vásquez, R. A., Dobson, R., Guigó, R. & Cogram, P. 20 Mar 2017 In : Frontiers in aging neuroscience. 9, 64

    Research output: Contribution to journalArticle

  14. Analysis of diagnoses extracted from Electronic health records in a large mental health Case Register

    Kovalchuk, Y., Stewart, R., Broadbent, M., Hubbard, T. J. P. & Dobson, R. J. B. 16 Feb 2017 In : PL o S One . 12, 2, p. e0171526 e0171526

    Research output: Contribution to journalArticle

  15. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Proitsi, P., Kim, M., Whiley, L., Simmons, A., Sattlecker, M., Velayudhan, L., Lupton, M. K., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C. Feb 2017 In : Alzheimer's & Dementia. 13, 2, p. 140-151 12 p.

    Research output: Contribution to journalArticle

  16. Learning patient similarity using joint distributed embeddings of treatment and diagnoses

    Ormandy, C., Ibrahim, Z. M. & Dobson, R. J. B. 2017 In : CEUR Workshop Proceedings. 1891, p. 30-35 6 p.

    Research output: Contribution to journalArticle

  17. Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid

    Voyle, N., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B. & Kiddle, S. J. 20 Dec 2016 In : JOURNAL OF ALZHEIMERS DISEASE. 55, 4, p. 1417-1427

    Research output: Contribution to journalArticle

  18. A novel automated high-content analysis workflow capturing cell population dynamics from induced pluripotent stem cell live imaging data

    Kerz, M., Folarin, A., Meleckyte, R., Watt, F. M., Dobson, R. J. & Danovi, D. 1 Oct 2016 Journal of Biomolecular Screening. SAGE Publications Inc., p. 887-896 10 p. (Journal of Biomolecular Screening; vol. 21)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  19. Challenges and opportunities for system biology standards and tools in medical research

    König, M., Oellrich, A., Waltemath, D., Dobson, R. J. B., Hubbard, T. J. P. & Wolkenhauer, O. 29 Sep 2016 Proceedings of the 7th Workshop on Ontologies and Data in Life Sciences, organized by the GI Workgroup Ontologies in Biomedicine and Life Sciences. CEUR-WS, Vol. 1692

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  20. Accepted/In press

    Genetic risk as a marker of amyloid-beta and tau in cerebrospinal fluid

    Voyle, N. J., Patel, H., Folarin, A., Newhouse, S., Johnston, C., Visser, P. J., Dobson, R. J. B., Kiddle, S. J. & EDAR and DESCRIPA 29 Sep 2016 (Accepted/In press) In : JOURNAL OF ALZHEIMERS DISEASE.

    Research output: Contribution to journalArticle

  21. SleepSight: A wearables-based relapse prevention system for Schizophrenia

    Kerz, M., Folarin, A., Meyer, N., Begale, M., MacCabe, J. & Dobson, R. J. 12 Sep 2016 UbiComp 2016 Adjunct - Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing. Association for Computing Machinery, Inc, p. 113-116 4 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  22. Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease

    Hakobyan, S., Harding, K., Aiyaz, M., Hye, A., Dobson, R., Baird, A., Liu, B., Harris, C. L., Lovestone, S. & Morgan, B. P. 6 Sep 2016 In : JOURNAL OF ALZHEIMERS DISEASE. 54, 2, p. 707-716 10 p.

    Research output: Contribution to journalArticle

  23. Accepted/In press

    Encoding Medication Episodes for Adverse Drug Event Prediction

    Wu, H., Ibrahim, Z., Iqbal, E. & Dobson, R. J. B. 9 Jul 2016 (Accepted/In press) The Thirty-Sixth Annual International Conference of the British Computer Society's Specialist Group on Artificial Intelligence .

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  24. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

    Fogh, I. , Lin, K. , Tiloca, C. , Rooney, J. , Gellera, C. , Diekstra, F. P. , Ratti, A. , Shatunov, A. , Van Es, M. A. , Proitsi, P. , Jones, A. , Sproviero, W. , Chiò, A. , McLaughlin, R. L. , Sorarù, G. , Corrado, L. , Stahl, D. , Del Bo, R. , Cereda, C. , Castellotti, B. & 29 others Glass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J. 1 Jul 2016 In : JAMA Neurology. 73, 7, p. 812-820 9 p.

    Research output: Contribution to journalArticle

  25. Combining clinical variables to optimize prediction of antidepressant treatment outcomes

    Iniesta, R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovsek, M. Z., Souery, D., Stahl, D., Dobson, R., Aitchison, K. J., Farmer, A., Lewis, C. M., McGuffin, P. & Uher, R. Jul 2016 In : Journal of psychiatric research. 78, p. 94-102 9 p.

    Research output: Contribution to journalArticle

  26. The language of mental health problems in social media

    Gkotsis, G., Oellrich, A., Hubbard, T., Dobson, R. JB., Liakata, M., Velupillai, S. & Dutta, R. 16 Jun 2016 The Third Computational Linguistics and Clinical Psychology Workshop (CLPsych). p. 63-73

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  27. Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

    Allen, G. I. , Amoroso, N. , Anghel, C. , Balagurusamy, V. , Bare, C. J. , Beaton, D. , Bellotti, R. , Bennett, D. A. , Boehme, K. L. , Boutros, P. C. , Caberlotto, L. , Caloian, C. , Campbell, F. , Chaibub Neto, E. , Chang, Y-C. , Chen, B. , Chen, C-Y. , Chien, T-Y. , Clark, T. , Das, S. & 81 others Davatzikos, C., Deng, J., Dillenberger, D., Dobson, R. J. B., Dong, Q., Doshi, J., Duma, D., Errico, R., Erus, G., Everett, E., Fardo, D. W., Friend, S. H., Fröhlich, H., Gan, J., St George-Hyslop, P., Ghosh, S. S., Glaab, E., Green, R. C., Guan, Y., Hong, M-Y., Huang, C., Hwang, J., Ibrahim, J., Inglese, P., Iyappan, A., Jiang, Q., Katsumata, Y., Kauwe, J. S. K., Klein, A., Kong, D., Krause, R., Lalonde, E., Lauria, M., Lee, E., Lin, X., Liu, Z., Livingstone, J., Logsdon, B. A., Lovestone, S., Ma, T., Malhotra, A., Mangravite, L. M., Maxwell, T. J., Merrill, E., Nagorski, J., Namasivayam, A., Narayan, M., Naz, M., Newhouse, S. J., Norman, T. C., Nurtdinov, R. N., Oyang, Y-J., Pawitan, Y., Peng, S., Peters, M. A., Piccolo, S. R., Praveen, P., Priami, C., Sabelnykova, V. Y., Senger, P., Shen, X., Simmons, A., Sotiras, A., Stolovitzky, G., Tangaro, S., Tateo, A., Tung, Y-A., Tustison, N. J., Varol, E., Vradenburg, G., Weiner, M. W., Xiao, G., Xie, L., Xie, Y., Xu, J., Yang, H., Zhan, X., Zhou, Y., Zhu, F., Zhu, H. & Zhu, S. 11 Apr 2016 In : Alzheimer's & Dementia. 12, 6, p. 645-653 9 p.

    Research output: Contribution to journalArticle

  28. Transcriptomics and the mechanisms of antidepressant efficacy

    Hodgson, K., Tansey, K. E., Powell, T., Coppola, G., Uher, R., Zvezdana Dernovšek, M., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Aitchison, K. J., Craig, I. W., Farmer, A. E., Breen, G., Mcguffin, P. & Dobson, R. 1 Jan 2016 In : European Neuropsychopharmacology. 26, 1, p. 105-112 8 p.

    Research output: Contribution to journalArticle

  29. A pathway based classification method for analyzing gene expression for Alzheimer's disease diagnosis

    Voyle, N., Keohane, A., Newhouse, S., Lunnon, K., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Hodges, A., Kiddle, S. & Dobson, R. JB. 2016 In : JOURNAL OF ALZHEIMERS DISEASE. 49, 3, p. 659-669 11 p.

    Research output: Contribution to journalArticle

  30. Microduplications at the pseudoautosomal SHOX locus in autism spectrum disorders and related neurodevelopmental conditions

    Tropeano, M. , Howley, D. , Gazzellone, M. J. , Wilson, C. E. , Ahn, J. W. , Stavropoulos, D. J. , Murphy, C. , Eis, P. S. , Hatchwell, E. , Dobson, R. J. B. , Robertson, D. , Holder, M. , Irving, M. , Josifova, D. , Nehammer, A. , Ryten, M. , Spain, D. , Pitts, M. , Bramham, J. , Asherson, P. & 9 others Curran, S., Vassos, E., Breen, G., Flinter, F., Ogilvie, C. M., Collier, D. A., Scherer, S. W., Mcalonan, G. M. & Murphy, D. G. 2016 In : Journal of Medical Genetics.

    Research output: Contribution to journalArticle

  31. Microdeletions of ELP4 are Associated with Language Impairment, Autism Spectrum Disorder and Mental Retardation

    Addis, L. , Ahn, J. W. , Dobson, R. J. B. , Dixit, A. , Ogilvie, C. M. , Pinto, D. , Vaags, A. K. , Coon, H. , Chaste, P. , Wilson, S. , Parr, J. R. , Andrieux, J. , Lenne, B. , Tumer, Z. , Leuzzi, V. , Aubell, K. , Koillinen, H. , Curran, S. R. , Marshall, C. R. , Scherer, S. W. & 3 others Strug, L. J., Collier, D. A. & Pal, D. K. 1 Sep 2015 In : Human Mutation. 36, 9

    Research output: Contribution to journalArticle

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