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Dr Richard Rosch

Research interests

I am a clinically trained neuroscientist, interested in the dynamics of large-scale neuronal networks, particularly in the context of childhood epilepsies and other neurological conditions. In my work I combine a variety of computational methods to understand the link between dysfunction at the level of individual neurons and whole-brain abnormal dynamics of the sort seen in patients with epileptic seizures. 

In my current work, I explore how we can use computational modelling to translate between insights from animal models and patient recordings. For this I will focus on two key genetic epilepsies and link clinical findings from patients with detailed light sheet microscopy recordings from corresponding zebrafish models of the disorders. 

Biographical details

After have completed my undergraduate neuroscience and medical degrees at the University of Oxford, I started postgraduate clinical training at King's College Hospital, London. At King's I was introduced to the fascinating new insights genomic medicine could offer for the care of paediatric epilepsy patients. I followed this interest by undertaking a PhD at University College London in Theoretical Neurobiology, learning computational tools to interrogate the mechanisms underlying the dynamic brain abnormalities seen on functional brain imaging and EEG. I am currently a Sir Henry Wellcome Postdoctoral Fellow at King's College London, combining my clinical interests and computational background on an exciting new model of epilepsy in zebrafish.

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