King's College London

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Professor Richard Trembath

Research interests

Investigation into the molecular mechanisms underlying pulmonary arterial disease; functional characterization of TGF-beta; cell signaling in vascular cells; identification of candidate susceptibility genes in the common skin disease psoriasis; genome-wide linkage analysis in familial cluster headache; functional characterization of human developmental disease genes, identified through homozygosity mapping in a range of autosomal recessive disorders; management of the National Autozygosity Mapping Resource (NAMR). Identification of major and minor susceptibility genes for psoriasis, using genome-wide linkage analysis, SNP-based approaches, construction and refinement of susceptibility haplotypes (with ProfessorJonathan Barker); functional role of psoriasis susceptibility genes (with ProfessorAdrian Hayday/Professor Frank Nestle); candidate gene approach to susceptibility gene identification in atopic dermatitis (with Professor Jonathan Barker). Identification of susceptibility loci in psoriasis.

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