Research output per year
Research output per year
Personal profile
Research interests
Genetics of cholestatic liver disease.
Research interests (short)
Genetics of cholestatic liver disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Clinical phenotype of adult-onset liver disease in patients with variants in ABCB4, ABCB11, and ATP8B1
Nayagam, J. S., Foskett, P., Strautnieks, S., Agarwal, K., Miquel, R., Joshi, D. & Thompson, R. J., Oct 2022, In: Hepatology Communications. 6, 10, p. 2654-2664 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency
Li, C. Z., Ogawa, H., Ng, S. S., Chen, X., Kishimoto, E., Sakabe, K., Fukami, A., Hu, Y. C., Mayhew, C. N., Hellmann, J., Miethke, A., Tasnova, N. L., Blackford, S. J. I., Tang, Z. M., Syanda, A. M., Ma, L., Xiao, F., Sambrotta, M., Tavabie, O., Soares, F., & 6 others, Apr 2022, In: JHEP Reports. 4, 4, 100446.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Maralixibat for the treatment of PFIC: Long-term, IBAT inhibition in an open-label, Phase 2 study
Loomes, K. M., Squires, R. H., Kelly, D., Rajwal, S., Soufi, N., Lachaux, A., Jankowska, I., Mack, C., Setchell, K. D. R., Karthikeyan, P., Kennedy, C., Dorenbaum, A., Desai, N. K., Garner, W., Jaecklin, T., Vig, P., Miethke, A. & Thompson, R. J., Sept 2022, In: Hepatology Communications. 6, 9, p. 2379-2390 12 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial
Thompson, R. J., Arnell, H., Artan, R., Baumann, U., Calvo, P. L., Czubkowski, P., Dalgic, B., D'Antiga, L., Durmaz, Ö., Fischler, B., Gonzalès, E., Grammatikopoulos, T., Gupte, G., Hardikar, W., Houwen, R. H. J., Kamath, B. M., Karpen, S. J., Kjems, L., Lacaille, F., Lachaux, A., & 14 others, 1 Jul 2022, (E-pub ahead of print) In: The Lancet Gastroenterology & Hepatology.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)20 Downloads (Pure) -
Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy
for Childhood Liver Disease Research Network (ChiLDReN), Harpavat, S., Hawthorne, K., Setchell, K. D. R., Rivas, MN., Henn, L., Beil, C. A., Karpen, S. J., Ng, VL., Alonso, E. M., Bezerra, J. A., Guthery, S. L., Horslen, S., Loomes, K. M., McKiernan, P., Magee, JC., Merion, R. M., Molleston, J. P., Rosenthal, P., Thompson, R. J., & 3 others, 11 Oct 2022, (E-pub ahead of print) In: Hepatology.Research output: Contribution to journal › Article › peer-review
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DRIVE Health CDT - Genotype to phenotype studies of inherited metabolic liver diseases using human iPSCs
Molokhia, M., Curcin, V., Dobson, R. & Thompson, R.
1/10/2021 → 30/09/2024
Project: Research
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Congenital portosystemic shunts - a natural model for oncogenesis in the liver
Thompson, R. & Tyraskis, A.
21/08/2019 → 20/02/2020
Project: Research
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Activities
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Postgraduate Course, American Liver meeting (AASLD)
Richard Thompson (Speaker)
2006 → …Activity: Participating in or organising an event › Participation in conference
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XIX International Bile Acid Meeting
Richard Thompson (Keynote/plenary speaker)
2006 → …Activity: Participating in or organising an event › Participation in conference
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British Pharmacological Society, Annual Meeting
Richard Thompson (Keynote/plenary speaker)
2005 → …Activity: Participating in or organising an event › Participation in conference
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Organised “Alex Mowat Paediatric Hepatology Update”
Richard Thompson (Organiser)
2004 → …Activity: Participating in or organising an event › Participation in conference
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Working Group on “Cholestatic and metabolic liver diseases” for the Second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition UK Medicines for Children’s Research Network, Clinical Study Group
Richard Thompson (Chair)
2004 → …Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
Prizes
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Wellcome Trust Advanced Fellow,
Thompson, Richard (Recipient), 2001
Prize: Fellowship awarded competitively