King's College London

Research portal

Professor Robert Howard

  1. Assistive technology and telecare to maintain independent living at home for people with dementia: the ATTILA RCT

    Gathercole, R., Bradley, R., Harper, E., Davies, L., Pank, L., Lam, N., Davies, A., Talbot, E., Hooper, E., Winson, R., Scutt, B., Montano, V. O., Nunn, S., Lavelle, G., Lariviere, M., Hirani, S., Brini, S., Bateman, A., Bentham, P., Burns, A. & 12 others, Dunk, B., Forsyth, K., Fox, C., Henderson, C., Knapp, M., Leroi, I., Newman, S., O'Brien, J., Poland, F., Woolham, J., Gray, R. & Howard, R., 1 Mar 2021, In: Health technology assessment (Winchester, England). 25, 19, p. 1-156 156 p.

    Research output: Contribution to journalArticlepeer-review

  2. Neuropsychiatric symptoms in limbic-predominant age-related TDP-43 encephalopathy and Alzheimer's disease

    Liu, K. Y., Reeves, S., McAleese, K. E., Attems, J., Francis, P., Thomas, A. & Howard, R., 1 Dec 2020, In: Brain. 143, 12, p. 3842-3849 8 p.

    Research output: Contribution to journalArticlepeer-review

  3. Functional cognitive disorder: dementia's blind spot

    Ball, H. A., McWhirter, L., Ballard, C., Bhome, R., Blackburn, D. J., Edwards, M. J., Fleming, S. M., Fox, N. C., Howard, R., Huntley, J., Isaacs, J. D., Larner, A. J., Nicholson, T. R., Pennington, C. M., Poole, N., Price, G., Price, J. P., Reuber, M., Ritchie, C., Rossor, M. N. & 5 others, Schott, J. M., Teodoro, T., Venneri, A., Stone, J. & Carson, A. J., 1 Oct 2020, In: Brain : a journal of neurology. 143, 10, p. 2895-2903 9 p.

    Research output: Contribution to journalArticlepeer-review

  4. Potentially inappropriate medication use in older adults with mild-moderate Alzheimer's disease: Prevalence and associations with adverse events

    NILVAD Study Group, 1 Jul 2020, In: Age and Ageing. 49, 4, p. 580-587 8 p.

    Research output: Contribution to journalArticlepeer-review

  5. Metacognition in functional cognitive disorder- a potential mechanism and treatment target

    Bhome, R., McWilliams, A., Huntley, J. D., Fleming, S. M. & Howard, R. J., 3 Sep 2019, In: Cognitive Neuropsychiatry. 24, 5, p. 311-321 11 p.

    Research output: Contribution to journalArticlepeer-review

  6. A statistical and biological response to an informatics appraisal of healthy aging gene signatures

    Timmons, J. A., Gallagher, I. J., Sood, S., Phillips, B., Crossland, H., Howard, R., Kraus, W. E. & Atherton, P. J., 2 Aug 2019, In: Genome Biology. 20, 1, 152.

    Research output: Contribution to journalArticlepeer-review

  7. Effect of computerised cognitive training on cognitive outcomes in mild cognitive impairment: A systematic review and meta-analysis

    Zhang, H., Huntley, J., Bhome, R., Holmes, B., Cahill, J., Gould, R. L., Wang, H., Yu, X. & Howard, R., 1 Aug 2019, In: BMJ Open. 9, 8, e027062.

    Research output: Contribution to journalReview articlepeer-review

  8. Misidentification Subtype of Alzheimer's Disease Psychosis Predicts a Faster Cognitive Decline

    D'Antonio, F., Reeves, S., Sheng, Y., McLachlan, E., de Lena, C., Howard, R. & Bertrand, J., 1 May 2019, In: CPT: Pharmacometrics and Systems Pharmacology. 8, 5, p. 308-315 8 p.

    Research output: Contribution to journalArticlepeer-review

  9. Assessment of need and practice for assistive technology and telecare for people with dementia—The ATTILA (Assistive Technology and Telecare to maintain Independent Living At home for people with dementia) trial

    Forsyth, K., Henderson, C., Davis, L., Singh Roy, A., Dunk, B., Curnow, E., Gathercole, R., Lam, N., Harper, E., Leroi, I., Woolham, J., Fox, C., O'Brien, J., Bateman, A., Poland, F., Bentham, P., Burns, A., Davies, A., Gray, R., Bradley, R. & 12 others, Knapp, M., Newman, S., McShane, R., Ritchie, C., Talbot, E., Hooper, E., Winson, R., Scutt, B., Ordonez, V., Nunn, S., Lavelle, G. & Howard, R., 1 Jan 2019, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 420-430 11 p.

    Research output: Contribution to journalArticlepeer-review

  10. Multi-component frailty assessment tools for older people with psychiatric disorders: A systematic review

    Sutton, J. L., Gould, R. L., Coulson, M. C., Ward, E. V., Butler, A. M., Smith, M., Lavelle, G., Rosa, A., Langridge, M. & Howard, R. J., 27 Dec 2018, In: Journal of the American Geriatrics Society.

    Research output: Contribution to journalArticlepeer-review

  11. Amisulpride for very late-onset schizophrenia-like psychosis: the ATLAS three-arm RCT

    Howard, R., Cort, E., Bradley, R., Harper, E., Kelly, L., Bentham, P., Ritchie, C., Reeves, S., Fawzi, W., Livingston, G., Sommerlad, A., Oomman, S., Nazir, E., Nilforooshan, R., Barber, R., Fox, C., Macharouthu, A., Ramachandra, P., Pattan, V., Sykes, J. & 6 others, Curran, V., Katona, C., Dening, T., Knapp, M., Romeo, R. & Gray, R., 1 Nov 2018, In: Health technology assessment (Winchester, England). 22, 67, p. 1-62 62 p.

    Research output: Contribution to journalArticlepeer-review

  12. Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): A randomised, controlled, double-blind trial

    Howard, R., Cort, E., Bradley, R., Harper, E., Kelly, L., Bentham, P., Ritchie, C., Reeves, S., Fawzi, W., Livingston, G., Sommerlad, A., Oomman, S., Nazir, E., Nilforooshan, R., Barber, R., Fox, C., Macharouthu, A. V., Ramachandra, P., Pattan, V., Sykes, J. & 5 others, Curran, V., Katona, C., Dening, T., Knapp, M. & Gray, R., 4 Jun 2018, In: The Lancet Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  13. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In: Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstractpeer-review

  14. VISUAL HALLUCINATIONS IN DEMENTIA: PRELIMINARY FINDINGS FROM THE STUDY OF HALLUCINATIONS IN PARKINSON’S DISEASE, EYE DISEASE AND DEMENTIA (SHAPED): 2017 Abstract Supplement

    Ffytche, D. H., Pinto, R., Krzyzanowski, H., Taylor, J-P., Collerton, D., O'Brien, J. T., Howard, R. J. & Aarsland, D., 20 Oct 2017, In: Alzheimer's & Dementia. 13, 7, Supplement, p. P1461-P1462

    Research output: Contribution to journalArticlepeer-review

  15. Predictors of treatment outcome in depression in later life: a systematic review and meta-analysis

    Tunvirachaisakul, C., Gould, R. L., Coulson, M. C., Ward, E. V., Reynolds, G., Gathercole, R. L., Grocott, H., Supasitthumrong, T., Tunvirachaisakul, A., Kimona, K. & Howard, R. J., 10 Oct 2017, In: Journal of Affective Disorders. 227, p. 164-182

    Research output: Contribution to journalReview articlepeer-review

  16. Reduced parahippocampal volume and psychosis symptoms in Alzheimer's disease

    McLachlan, E., Bousfield, J., Howard, R. & Reeves, S., 25 Jul 2017, In: International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  17. Dementia prevention, intervention, and care

    Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., Ballard, C., Banerjee, S., Burns, A., Cohen-Mansfield, J., Cooper, C., Fox, N., Gitlin, L. N., Howard, R., Kales, H. C., Larson, E. B., Ritchie, K., Rockwood, K., Sampson, E. L., Samus, Q. & 4 others, Schneider, L. S., Selbæk, G., Teri, L. & Mukadam, N., 20 Jul 2017, In: Lancet.

    Research output: Contribution to journalArticlepeer-review

  18. A Population approach to guide amisulpride dose adjustments in older patients with Alzheimer's disease

    Reeves, S., Bertrand, J., McLachlan, E., D'Antonio, F., Brownings, S., Nair, A., Greaves, S., Smith, A., Dunn, J., Marsden, P., Kessler, R., Uchida, H., Taylor, D. & Howard, R., 1 Jul 2017, In: Journal of Clinical Psychiatry. 78, 7, p. e844-e851

    Research output: Contribution to journalArticlepeer-review

  19. Therapeutic D2/3 receptor occupancies and response with low amisulpride blood concentrations in very late-onset schizophrenia-like psychosis (VLOSLP)

    Reeves, S., Eggleston, K., Cort, E., Mclachlan, E., Brownings, S., Nair, A., Greaves, S., Smith, A., Dunn, J., Marsden, P., Kessler, R., Taylor, D., Bertrand, J. & Howard, R., 23 Jun 2017, In: International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  20. Therapeutic window of dopamine D2/3 receptor occupancy to treat psychosis in Alzheimer's disease

    Reeves, S. J., McLachlan, E., Bertrand, J., Antonio, F. D., Brownings, S. L., Nair, A., Greaves, S., Smith, A., Taylor, D. M., Dunn, J., Marsden, P., Kessler, R. & Howard, R. J., 1 Apr 2017, In: Brain. 140, 4, p. 1117-1127 11 p.

    Research output: Contribution to journalArticlepeer-review

  21. Effects of electromagnetic fields emitted by GSM phones on working memory: a meta-analysis

    Zubko, O., Gould, R. L., Gay, H. C., Cox, H. J., Coulson, M. C. & Howard, R. J., 1 Feb 2017, In: International Journal of Geriatric Psychiatry. 32, 2, p. 125-135 11 p.

    Research output: Contribution to journalArticlepeer-review

  22. Lack of Early Improvement with Antipsychotics is a Marker for Subsequent Non-Response in Behavioral and Psychological Symptoms of Dementia: Analysis of CATIE-AD Data

    Yoshida, K., Roberts, R., Suzuki, T., Lebowitz, B., Reeves, S., Howard, R., Abe, T., Mimura, M. & Uchida, H., 30 Jan 2017, In: American Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  23. Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial)

    Knapp, M., King, D., Romeo, R., Adams, J., Baldwin, A., Ballard, C., Banerjee, S., Barber, R., Bentham, P., Brown, R. G., Burns, A., Dening, T., Findlay, D., Holmes, C., Johnson, T., Jones, R., Katona, C., Lindesay, J., Macharouthu, A., McKeith, I. & 5 others, McShane, R., O'Brien, J. T., Phillips, P. P. J., Sheehan, B. & Howard, R., 13 Oct 2016, In: International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  24. Service and treatment engagement of people with very late-onset schizophrenia-like psychosis

    Lam, C. C. S. F., Reeves, S. J., Stewart, R. & Howard, R., 1 Aug 2016, In: Psychiatrist. 40, 4, p. 185-186 2 p.

    Research output: Contribution to journalArticlepeer-review

  25. The importance of sustained attention in early Alzheimer's disease

    Huntley, J., Hampshire, A., Bor, D., Owen, A. M. & Howard, R. J., 18 Jul 2016, In: International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  26. European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease - The substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow

    Meulenbroek, O., O'Dwyer, S., De Jong, D., Van Spijker, G., Kennelly, S., Cregg, F., Rikkert, M. O., Abdullah, L., Wallin, A., Walsh, C., Coen, R., Kenny, R. A., Daly, L., Segurado, R., Borjesson-Hanson, A., Crawford, F., Mullan, M., Lucca, U., Banzi, R., Pasquier, F. & 9 others, Breuilh, L., Riepe, M., Kalman, J., Molloy, W., Tsolaki, M., Howard, R., Jessica Adams, M. O., Gaynor, S. & Lawlor, B., 1 Jul 2016, In: BMJ Open. 6, 7, e011584.

    Research output: Contribution to journalArticlepeer-review

  27. Psychometric properties of multicomponent tools designed to assess frailty in older adults: A systematic review

    Sutton, J. L., Gould, R. L., Daley, S., Coulson, M., Ward, E., Butler, A., Nunn, S. & Howard, R., 29 Feb 2016, In: BMC Geriatrics . 16, 1

    Research output: Contribution to journalReview articlepeer-review

  28. Provision of specialist continuing care services for older adults across the UK

    Jenkinson, J. & Howard, R., 22 Jan 2016, In: International psychogeriatrics / IPA. p. 1-8 8 p.

    Research output: Contribution to journalArticlepeer-review

  29. Tests of pattern separation and pattern completion in humans-A systematic review

    Liu, K. Y., Gould, R. L., Coulson, M. C., Ward, E. V. & Howard, R. J., 11 Jan 2016, In: Hippocampus.

    Research output: Contribution to journalArticlepeer-review

  30. Nursing home placement in the Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD) trial: Secondary and post-hoc analyses

    Howard, R., McShane, R., Lindesay, J., Ritchie, C., Baldwin, A., Barber, R., Burns, A., Dening, T., Findlay, D., Holmes, C., Jones, R., Jones, R., McKeith, I., Macharouthu, A., O'Brien, J., Sheehan, B., Juszczak, E., Katona, C., Hills, R., Knapp, M. & 7 others, Ballard, C., Brown, R. G., Banerjee, S., Adams, J., Johnson, T., Bentham, P. & Phillips, P. P. J., 1 Dec 2015, In: Lancet Neurology. 14, 12, p. 1171-1181 11 p.

    Research output: Contribution to journalArticlepeer-review

  31. The Effect of an Online Cognitive Training Package in Healthy Older Adults: An Online Randomized Controlled Trial

    Corbett, A., Owen, A., Hampshire, A., Grahn, J., Stenton, R., Dajani, S., Burns, A., Howard, R., Williams, N., Williams, G. & Ballard, C., 1 Nov 2015, In: Journal Of The American Medical Directors Association. 16, 11, p. 990-997 8 p.

    Research output: Contribution to journalArticlepeer-review

  32. A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status

    Sood, S., Gallagher, I. J., Lunnon, K., Rullman, E., Keohane, A., Crossland, H., Phillips, B. E., Cederholm, T., Jensen, T., van Loon, L. J. C., Lannfelt, L., Kraus, W. E., Atherton, P. J., Howard, R., Gustafsson, T., Hodges, A. & Timmons, J. A., 7 Sep 2015, In: Genome Biology. 16, 1, 17 p., 185.

    Research output: Contribution to journalArticlepeer-review

  33. Opioids for agitation in dementia

    Brown, R., Howard, R., Candy, B. & Sampson, E. L., 14 May 2015, In: Cochrane Database of Systematic Reviews. 2015, 5, CD009705.

    Research output: Contribution to journalReview articlepeer-review

  34. Do cognitive interventions improve general cognition in dementia? A meta-analysis and meta-regression

    Huntley, J., Gould, R., Liu, K., Smith, M. & Howard, R., 2 Apr 2015, In: BMJ Open. 5, 4, 12 p., e005247.

    Research output: Contribution to journalArticlepeer-review

  35. Could pheromones have a place in the management of agitation in dementia?

    Liu, K. & Howard, R. J., 1 Feb 2015, In: International Journal of Geriatric Psychiatry. 30, 2, p. 219-220 2 p.

    Research output: Contribution to journalLetterpeer-review

  36. Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition

    Cummings, J., Mintzer, J., Brodaty, H., Sano, M., Banerjee, S., Devanand, D. P., Gauthier, S., Howard, R., Lanctôt, K., Lyketsos, C. G., Peskind, E., Porsteinsson, A. P., Reich, E., Sampaio, C., Steffens, D., Wortmann, M. & Zhong, K., 12 Jan 2015, In: International psychogeriatrics / IPA. 27, 1, p. 7-17 11 p.

    Research output: Contribution to journalArticlepeer-review

  37. Cognitive debt and Alzheimer's disease

    Marchant, N. L. & Howard, R. J., 1 Jan 2015, In: JOURNAL OF ALZHEIMERS DISEASE. 44, 3, p. 755-770 16 p.

    Research output: Contribution to journalArticlepeer-review

  38. Hippocampal abnormalities and age in chronic schizophrenia: Morphometric study across the adult lifespan

    Pujol, N., Penadés, R., Junqué, C., Dinov, I., Fu, C. H. Y., Catalán, R., Ibarretxe-Bilbao, N., Bargalló, N., Bernardo, M., Toga, A., Howard, R. J. & Costafreda, S. G., Nov 2014, In: British journal of psychiatry. 205, 5, p. 369-375 7 p.

    Research output: Contribution to journalArticlepeer-review

  39. NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease

    Lawlor, B., Kennelly, S., O'Dwyer, S., Cregg, F., Walsh, C., Coen, R., Kenny, R. A., Howard, R., Murphy, C., Adams, J., Daly, L., Segurado, R., Gaynor, S., Crawford, F., Mullan, M., Lucca, U., Banzi, R., Pasquier, F., Breuilh, L., Riepe, M. & 6 others, Kalman, J., Wallin, A., Borjesson, A., Molloy, W., Tsolaki, M. & Olde Rikkert, M., 9 Oct 2014, In: BMJ open. 4, 10, p. e006364

    Research output: Contribution to journalArticlepeer-review

  40. Towards a therapeutic window of D2/3 occupancy for treatment of psychosis in Alzheimer's disease, with [18F] fallypride positron emission tomography

    Clark-Papasavas, C., Dunn, J. T., Greaves, S., Mogg, A., Gomes, R., Brownings, S., Liu, K., Nwosu, B., Marsden, P., Joemon, J., Cleij, M., Kessler, R., Howard, R. & Reeves, S., Oct 2014, In: International Journal of Geriatric Psychiatry. 29, 10, p. 1001-1009 9 p.

    Research output: Contribution to journalArticlepeer-review

  41. Review: Supervised withdrawal plus other interventions reduces benzodiazepine use in older persons

    Gould, R. L., Coulson, M. C., Patel, N., Highton-Williamson, E., Howard, R. J., Vicens Caldentey, C., Hinrichsen, G. A. & Leipzig, R. M., 16 Sep 2014, In: Annals of Internal Medicine. 161, 6, p. JC2-JC3

    Research output: Contribution to journalComment/debatepeer-review

  42. Psychotic major depression in older people: a systematic review

    Gournellis, R., Oulis, P. & Howard, R., Aug 2014, In: International Journal of Geriatric Psychiatry. 29, 8, p. 784-796 13 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  43. Interventions for reducing benzodiazepine use in older people: meta-analysis of randomized controlled trials

    Gould, R., Coulson, M., Patel, N., Highton-Williamson, E. & Howard, R., Feb 2014, In: British Journal of Psychiatry. 204, 2, p. 98-107 10 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  44. Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis

    Fratta, P., Charnock, J., Collins, T., Devoy, A., Howard, R., Malaspina, A., Orrell, R., Sidle, K., Clarke, J., Shoai, M., Lu, C. H., Hardy, J., Plagnol, V. & Fisher, E. M. C., 1 Jan 2014, In: Journal of Neurology, Neurosurgery and Psychiatry. 85, 5, p. 506-508 3 p.

    Research output: Contribution to journalArticlepeer-review

  45. Prescription of antipsychotics in people with dementia

    Ballard, C., Corbett, A. & Howard, R., 2014, In: Br J Psychiat. 205, 1, p. 4-5 2 p.

    Research output: Contribution to journalArticlepeer-review

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