Search results

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  PET (positron emission tomography) Imaging of Copper Trafficking and Metabolism as an Early Diagnostic for Alzheimer's Disease

  Blower, P. (Primary Investigator), Dunn, J. (Co-Investigator), Hammers, A. (Co-Investigator), Howard, R. (Co-Investigator), Jauregui-Osoro, M. (Co-Investigator), Marsden, P. (Co-Investigator), Reeves, S. (Co-Investigator) & Turkheimer, F. (Co-Investigator)

  1/10/2015 → 30/06/2019

  Project: Research

• PET (positron emission tomography) imaging of copper trafficking and metabolism as an early diagnostic for Alzheimer's disease

  Blower, P. (Primary Investigator), Dunn, J. (Co-Investigator), Hammers, A. (Co-Investigator), Howard, R. (Co-Investigator), Jauregui-Osoro, M. (Co-Investigator), Reeves, S. (Co-Investigator) & academic, A. (Co-Investigator)

  1/07/2015 → 1/07/2018

  Project: Research

• De Negative Thoughts Increase Risk for Alzheimer's Disease? A Proof of Principle Study of Cognitive Debt.

  Howard, R. (Primary Investigator), Marchant, N. (Co-Investigator) & Steves, C. (Co-Investigator)

  1/06/2015 → 30/05/2018

  Project: Research

• Pathway-driven identification of therapeutic targets for combatting Alzheimer's disease

  Killick, R. (Primary Investigator), Howard, R. (Co-Investigator) & Srivastava, D. (Co-Investigator)

  MRC Medical Research Council

  1/06/2015 → 31/05/2019

  Project: Research

• Computer aided primary care pathway for stratified dementia diagnosis: validation and pilot randomised controlled trial of patient benefit

  Costafreda-Gonzalez, S. (Primary Investigator), Howard, R. (Co-Investigator), Rebollo-Mesa, I. (Co-Investigator), Simmons, A. (Co-Investigator) & Stewart, R. (Co-Investigator)

  1/01/2015 → 31/12/2019

  Project: Research

• HTA-SYMBAD - StudY of Mirtazapine or carBamazepine for Agitation in Dementia

  Ballard, C. (Primary Investigator), Francis, P. (Co-Investigator) & Howard, R. (Co-Investigator)

  1/01/2015 → 31/12/2017

  Project: Research

• Quantification of TAU pathology in vivo and investigation for links with beta-amyloid pathology and cognitive decline in patients with Alzheimer's disease: An in vivo [18F]-T807 and [18F]-florbetapir PET study

  Politis, M. (Primary Investigator), Ballard, C. (Co-Investigator), Howard, R. (Co-Investigator) & Turkheimer, F. (Co-Investigator)

  1/10/2014 → 30/09/2018

  Project: Research

• Differential diagnosis and progression assessment of dementia using large-scale machine learning

  Aljabar, P. (Primary Investigator), Hammers, A. (Co-Investigator), Howard, R. (Co-Investigator) & Simmons, A. (Co-Investigator)

  1/01/2014 → 31/12/2017

  Project: Research

• The role of the circadian clock in Alzheimer's Disease

  Baird, A. (Primary Investigator) & Howard, R. (Co-Investigator)

  KHP King's Health Partners

  18/11/2013 → 17/11/2015

  Project: Research

• Peri-operative Enhanced Recovery hip FracturE Care of paTiEnts with Dementia : PERFECTED

  Ballard, C. (Primary Investigator) & Howard, R. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/11/2013 → 31/10/2016

  Project: Research

• Imaging neuroinflammation in Alzheimer's Disease using the novel TSPO tracer [11C] PBR 28

  Reeves, S. (Primary Investigator), Howard, R. (Co-Investigator), Simmons, A. (Co-Investigator) & Turkheimer, F. (Co-Investigator)

  1/09/2013 → 31/08/2014

  Project: Research

• Minocycline in Alzheimer's Disease Efficacy Trial : The MADE trial

  Howard, R. (Primary Investigator), Ballard, C. (Co-Investigator), Lovestone, S. (Co-Investigator), Reeves, S. (Co-Investigator) & Simmons, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/06/2013 → 31/05/2018

  Project: Research

• Health of older people with alcohol misuse in primary care

  Ashworth, M. (Primary Investigator), Howard, R. (Co-Investigator) & Schofield, P. (Co-Investigator)

  1/06/2013 → 30/11/2013

  Project: Research

• Assistive Technology and Telecare to maintain Independent Living At home for people with dementia: The ATTILA Trial.

  Howard, R. (Primary Investigator) & Knapp, M. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/01/2013 → 30/06/2019

  Project: Research

• Post-operative study evaluating inpatient interventions in dementia occurring following fractured neck or femur - POSEIDDON - Project

  Howard, R. (Primary Investigator) & Ballard, C. (Co-Investigator)

  1/10/2012 → 30/09/2017

  Project: Research

• Towards an evidence-based clinical management of visual hallucinations: prevalence, prognosis, impact and pathophysiology

  Howard, R. (Primary Investigator), Ffytche, D. (Co-Investigator), Knapp, M. (Co-Investigator), Lawrence, V. (Co-Investigator), Price, J. (Co-Investigator) & Stewart, R. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/06/2012 → 30/11/2018

  Project: Research

• A pragmatic exploritory study of the acceptability and treatment effects of Mindfulness Based Cognitive Therapy (MBCT) in older people suffering from recurrent depression in secondary care

  Norman, I. (Primary Investigator), Goldsmith, K. (Co-Investigator), Gould, R. (Co-Investigator), Howard, R. (Co-Investigator) & Pickles, A. (Co-Investigator)

  1/04/2012 → 1/04/2015

  Project: Research

• A European multicentre double-blind plaebo-controlled phase III trial of nilvadIpine in mild to moderate Alzheimer's disease NILVAD

  Howard, R. (Primary Investigator) & Murphy, C. (Co-Investigator)

  EC European Commission

  1/01/2012 → 30/06/2017

  Project: Research

• A Practical randomised controlled double-blind trial of antipsychotic treatment of very late-onset schizophrenia-like psychosis: The Atlas Trial

  Howard, R. (Primary Investigator)

  NIHR National Institute For Health & Care Research

  1/10/2011 → 31/10/2017

  Project: Research

• Tau Biology (Diane Hanger), Synaptosomes (Professor Colin Dingwall) and Proteomics of Lewy Body Dementia

  Howard, R. (Primary Investigator)

  1/09/2011 → 31/08/2012

  Project: Research

• New Transgenic Animals for AD Research (NTAIL)

  Howard, R. (Primary Investigator)

  1/09/2011 → 31/08/2014

  Project: Research

• Protein Biomarkers Assays for the Rapid Diagnosis of Strokes

  Howard, R. (Primary Investigator)

  1/06/2011 → 31/05/2014

  Project: Research

• Modification of vascular risk factors and the course of Alzheimer's disease: Stage 1. How effective are the treatment of hypertension and hypercholesterolaemia in mild to moderate AD., BUPA & ART joint application

  Howard, R. (Primary Investigator)

  1/01/2011 → 30/06/2012

  Project: Research

• Antidepressant Controlled trial for Negative Symptoms in Schizophrenia (ACTIONS)

  Murray, R. (Primary Investigator), Howard, R. (Co-Investigator) & Jamieson-Craig, T. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  6/10/2010 → 31/10/2014

  Project: Research

• Cerebral blood flow imaging: A novel, objective and quantitive assay of post operative pain and it's treatment.

  Williams, S. (Primary Investigator), Howard, R. (Co-Investigator) & Zelaya, F. (Co-Investigator)

  1/10/2010 → 31/03/2012

  Project: Research

• Functional anatomy and impact of cognitive training using chunking in working memory in early Alzheimer's disease.

  Huntley, J. (Primary Investigator) & Howard, R. (Co-Investigator)

  MRC Medical Research Council

  5/08/2010 → 4/08/2014

  Project: Research

• Low dose morphine treatment for agitated behaviour in AD

  Howard, R. (Primary Investigator)

  4/08/2010 → 5/08/2013

  Project: Research

• Functional anatomy and impact of cognitive training in chunking on working memory in early Alzheimer's disease.

  Howard, R. (Primary Investigator)

  1/08/2010 → 31/07/2013

  Project: Research

• A randomised controlled trial of carbamazepine and citalopram in the management of agitate and aggressive behaviour in Alzheimer's disease

  Howard, R. (Primary Investigator)

  1/08/2010 → 31/03/2014

  Project: Research

• A pragmatic exploratory study of the acceptability and treatment effects of Mindfulness Based Cognitive Therapy (MBCT) in older people suffering from recurrent depression in secondary care

  Norman, I. (Primary Investigator), Coster, S. (Co-Investigator), Gould, R. (Co-Investigator), Howard, R. (Co-Investigator) & Pickles, A. (Co-Investigator)

  1/04/2010 → 1/04/2015

  Project: Research

• DOMINO - application for extension

  Howard, R. (Primary Investigator)

  12/02/2010 → 31/03/2011

  Project: Research

• Citalopram for the treatment of agitation/aggression in patients with vascular dementia: a randomised double blind placebo controlled clinical trial (CAVE)

  Ballard, C. (Primary Investigator), Jones, E. (Primary Investigator), Aarsland, D. (Co-Investigator), Hanney, M. L. (Co-Investigator) & Howard, R. (Co-Investigator)

  1/11/2009 → 31/12/2011

  Project: Research

• Can brain training lead to short term and sustained improvements in cognitive function?

  Ballard, C. (Primary Investigator) & Howard, R. (Co-Investigator)

  Alzheimer's Society

  1/09/2009 → 31/08/2011

  Project: Research

• Generation of preference-based indices from demqol and demqol-proxy for use in economic evaluation.

  Banerjee, S. (Primary Investigator), Howard, R. (Co-Investigator) & Knapp, M. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/01/2009 → 31/08/2011

  Project: Research

• IES Platform - A feasibility study to develop a novel complex internet based cognitive training trial to improve cognition and instrumental activities of daily living in people (IADLS) with mild Alzheimer`s disease.

  Brown, R. (Co-Investigator) & Howard, R. (Co-Investigator)

  1/06/2008 → 31/05/2010

  Project: Research

• Donepezil and memantine in moderate to severe Alzheimer`s deseases - the DOMINO trial

  Howard, R. (Primary Investigator)

  Alzheimer's Society

  1/08/2007 → 31/03/2014

  Project: Research

• Functional anatomy of cognitive improvement in schizophrenia

  Brown, R. (Co-Investigator), David, A. (Co-Investigator), Howard, R. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/03/2007 → 28/02/2010

  Project: Research

• Donepezil and memantine in moderate to severe Alzheimer`s disease - DOMINO TRIAL.

  Howard, R. (Primary Investigator)

  MRC Medical Research Council

  1/12/2006 → 31/03/2014

  Project: Research

• Using the fMRI BOLD response to monitor disease progression in Alzheimer's disease

  Brown, R. (Co-Investigator), Gould, R. (Co-Investigator) & Howard, R. (Co-Investigator)

  Alzheimer's Research UK

  1/07/2006 → 1/06/2008

  Project: Research

• The functional anatomy of apathy: A functional MRI study in progressive supranuclear palsy and alzheimer's disease

  Brown, R. (Co-Investigator), Howard, R. (Co-Investigator), Leigh, P. (Co-Investigator) & Williams, S. (Co-Investigator)

  MRC Medical Research Council

  1/10/2005 → 30/09/2008

  Project: Research

• Apathy in Alzheimer's disease: Functional anatomy and the Role of Cholinesterase inhibitors.

  Brown, R. (Co-Investigator), Howard, R. (Co-Investigator), Leigh, P. (Co-Investigator), Stanton, B. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/06/2005 → 1/05/2008

  Project: Research

• Emotional processing and mood in Parkinson's disease: a clinical and experimental investigation.

  Brown, R. (Co-Investigator), Howard, R. (Co-Investigator) & Leigh, P. (Co-Investigator)

  Parkinson's UK

  1/04/2005 → 30/04/2008

  Project: Research

• The forgotten generation service development and evaluation project. Delivery and evaluation of an innovative specialist services for older people with schizophrenia.

  Harris, T. (Co-Investigator) & Howard, R. (Co-Investigator)

  1/04/2005 → 30/09/2007

  Project: Research

• Affective, cognitive and motivational symptoms, structural brain abnormalities and outcome in late life depression.

  Brown, R. (Co-Investigator), Howard, R. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/07/2004 → 30/06/2007

  Project: Research

• Imaging longitudinal changes in brain function in Alzheimer's Disease.

  Brown, R. (Co-Investigator), Gould, R. (Co-Investigator), Howard, R. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/06/2004 → 31/05/2007

  Project: Research

• Imaging longitudinal changes in the functional anatomy of episodic memory in Alzheimer's Disease.

  Brown, R. (Co-Investigator), Gould, R. (Co-Investigator), Howard, R. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/06/2004 → 31/05/2007

  Project: Research

• Towards Robust Statistical Comparisons of White Tracts in the Human Brain

  Barker, G. (Co-Investigator), Howard, R. (Co-Investigator) & Williams, S. (Co-Investigator)

  Wellcome Trust

  1/08/2003 → 31/07/2006

  Project: Research

• An RCT of a cholinesterase inhibitor and atypical antipsychotic in the management of agitation in dementia

  Brown, R. (Co-Investigator), Howard, R. (Co-Investigator) & Knapp, M. (Co-Investigator)

  MRC Medical Research Council

  1/07/2003 → 30/06/2006

  Project: Research

• CAN THE BEHAVIOUR SYMPTOMS OF PEOPLE SEVERELY AFFECTED BY DEMENTIA BE EFFECTIVELY AND SAFELY MANAGED WITHOUT USE OF REGULAR PSYCHOTROPIC MEDIATION?

  Howard, R. (Co-Investigator)

  Alzheimer's Society

  1/12/2002 → 30/11/2005

  Project: Research

• Fellowship - Measuring Neurodegeneration in Parkinsonian Syndromes Using Multi-Model MRI

  Brown, R. (Co-Investigator), Howard, R. (Co-Investigator), Leigh, P. (Co-Investigator), Simmons, A. (Co-Investigator), Williams, S. (Co-Investigator) & academic, A. (Co-Investigator)

  Wellcome Trust

  1/09/2002 → 30/11/2005

  Project: Research