King's College London

Research portal

Dr Robert Keers

  1. Polygenic Risk Scores for Schizophrenia and Major Depression are associated with Socio-Economic Indicators of Adversity in two British Community Samples

    Machlitt-Northen, S., Keers, R., Munroe, P., Howard, D. & Pluess, M., 14 Nov 2022, In: Translational psychiatry. 12, 1, 477.

    Research output: Contribution to journalArticlepeer-review

  2. Polygenic Scores for Schizophrenia and Major Depression are Associated with Psychosocial Risk Factors in Children: Evidence of Gene-Environment Correlation

    Machlitt-Northen, S., Keers, R., Munroe, P., Howard, D., Trubetskoy, V. & Pluess, M., Oct 2022, In: Journal of Child Psychology and Psychiatry. 63, 10, p. 1140-1152 13 p.

    Research output: Contribution to journalArticlepeer-review

  3. Gene–Environment Correlation over Time: A Longitudinal Analysis of Polygenic Risk Scores for Schizophrenia and Major Depression in Three British Cohorts Studies

    Machlitt-Northen, S., Keers, R., Munroe, P., Howard, D. & Pluess, M., 24 Jun 2022, In: Genes. 13, 7, p. 1136 1136.

    Research output: Contribution to journalArticlepeer-review

  4. Dimensions of temperament and character as predictors of antidepressant discontinuation, response and adverse reactions during treatment with nortriptyline and escitalopram

    Köhler-Forsberg, O., Keers, R., Uher, R., Hauser, J., Maier, W., Rietschel, M., McGuffin, P., Farmer, A. E., Aitchison, K. J. & Mors, O., 12 Nov 2021, (E-pub ahead of print) In: Psychological Medicine. p. 1-9

    Research output: Contribution to journalArticlepeer-review

  5. Genetic architecture of Environmental Sensitivity reflects multiple heritable components: a twin study with adolescents

    Assary, E., Zavos, H. M. S., Krapohl, E., Keers, R. & Pluess, M., 2021, In: Molecular Psychiatry. p. 4896–4904

    Research output: Contribution to journalArticlepeer-review

  6. Is digital cognitive behavioural therapy for insomnia effective in treating sub-threshold insomnia: a pilot RCT

    Denis, D., Eley, T. C., Rijsdijk, F., Zavos, H. M. S., Keers, R., Espie, C. A., Luik, A. I., Badini, I., Derveeuw, S., Hodsoll, J. & Gregory, A. M., 1 Feb 2020, In: Sleep Medicine. 66, p. 174-183 10 p.

    Research output: Contribution to journalArticlepeer-review

  7. The utility of the SCAS-C/P to detect specific anxiety disorders among clinically anxious children

    Reardon, T., Creswell, C., Lester, K., Arendt, K., Blatter-Meunier, J., Bögels, S. M., Coleman, J. R. I., Cooper, P., Heiervang, E., Herren, C., Hogendoorn, S. M., Hudson, J. L., Keers, R., Lyneham, H. J., Marin, C., Nauta, M., Rapee, R. M., Roberts, S., Schneider, S., Silverman, W. K., & 4 othersThastum, M., Thirlwall, K., Wergeland, G. J. & Eley, T. C., 31 Dec 2018, (Accepted/In press) In: Psychological Assessment.

    Research output: Contribution to journalArticlepeer-review

  8. DNA methylation of FKBP5 and response to exposure-based psychological therapy

    Roberts, S., Keers, R., Breen, G., Coleman, J. R. I., Jöhren, P., Kepa, A., Lester, K. J., Margraf, J., Scheider, S., Teismann, T., Wannemüller, A., Eley, T. C. & Wong, C. C. Y., 18 Oct 2018, (E-pub ahead of print) In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics.

    Research output: Contribution to journalArticlepeer-review

  9. Genome-wide expression and response to exposure-based psychological therapy for anxiety disorders

    Roberts, S., Wong, C. C. Y., Breen, G., Coleman, J. R. I., De Jong, S., Jöhren, P., Keers, R., Curtis, C., Lee, S. H., Margraf, J., Schneider, S., Teismann, T., Wannemüller, A., Lester, K. J. & Eley, T. C., 29 Aug 2017, (E-pub ahead of print) In: Translational psychiatry. 7, 8, 1219.

    Research output: Contribution to journalArticlepeer-review

  10. Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders

    Lester, K. J., Coleman, J., Roberts, S., Keers, R., Breen, G., Bögels, S., Creswell, C., Hudson, J. L., Mckinnon, A., Nauta, M., Rapee, R. M., Schneider, S., Silverman, W. K., Thastum, M., Waite, P., Wergeland, G. J. H. & Eley, T. C., 27 Jun 2016, (E-pub ahead of print) In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics.

    Research output: Contribution to journalArticlepeer-review

  11. A genome-wide test of the differential susceptibility hypothesis reveals a genetic predictor of differential response to psychological treatments for child anxiety disorders

    Keers, R., Coleman, J., Lester, K. J., Roberts, S. L., Breen, G. D., Thastum, M., Bögels, S., Schneider, S., Heiervang, E., Meiser-Stedman, R., Nauta, M., Creswell, C., Thirlwall, K., Rapee, R. M., Hudson, J. L., Lewis, C. M., Plomin, R. J. & Eley, T. C., 5 Apr 2016, In: Psychotherapy and Psychosomatics. 85, 3, p. 146-158 13 p.

    Research output: Contribution to journalArticlepeer-review

  12. Genome-wide association study of response to cognitive behavioural therapy in children with anxiety disorders

    Coleman, J., Lester, K. J., Keers, R., Roberts, S., Curtis, C. J., Arendt, K., Bogels, S., Cooper, P., Creswell, C., Dalgleish, T., Hartman, C., Heiervang, E., Hötzel, K., Hudson, J. L., In-Albon, T., Lavallee, K., Lyneham, H., Marin, C., Meiser-Stedman, R., Morris, T., & 11 othersNauta, M., Rapee, R. M., Schneider, S., Schneider, S. C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J., Breen, G. D. & Eley, T. C., 17 Mar 2016, (E-pub ahead of print) In: British Journal of Psychiatry. 208, 3

    Research output: Contribution to journalArticlepeer-review

  13. HPA axis related genes and response to psychological therapies: Genetics and epigenetics

    Roberts, S., Keers, R., Lester, K. J., Coleman, J., Breen, G., Arendt, K., Blatter-Meunier, J., Cooper, P., Creswell, C., Fjermestad, K., Havik, O. E., Herren, C., Hogendoorn, S. M., Hudson, J. L., Krause, K., Lyneham, H. J., Morris, T., Nauta, M., Rapee, R. M., Rey, Y., & 8 othersSchneider, S., Schneider, S. C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Eley, T. C. & Wong, C. C. Y., 7 Oct 2015, (E-pub ahead of print) In: Depression and Anxiety. 10 p.

    Research output: Contribution to journalArticlepeer-review

  14. Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders

    Lester, K., Roberts, S., Keers, R., Coleman, J., Breen, G., Wong, C., Xu, X., Arendt, K., Blatter-Meunier, J., Bögels, S., Cooper, P., Creswell, C., Heiervang, E., Herren, C., Hogendoorn, S., Hudson, J., Krause, K., Lyneham, H., McKinnon, A., Morris, T., & 12 othersNauta, M., Rapee, R., Rey, Y., Schneider, S., Schneider, S., Silverman, W., Smith, P., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J. & Eley, T., 20 Aug 2015, In: British Journal of Psychiatry. 7 p.

    Research output: Contribution to journalArticlepeer-review

  15. Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study

    Hudson, J., Keers, R., Roberts, S., Coleman, J., Breen, G., Arendt, K., Bogels, S., Cooper, P., Creswell, C., Hartman, C. A., Heiervang, E., Hotzel, K., In-Albon, T., Lavallee, K., Lyneham, H. J., Marin, C. E., McKinnon, A., Meiser-Stedman, R., Morris, T., Nauta, M., & 10 othersRapee, R., Schneider, S., Schneider, S., Silverman, W., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J., Lester, K. & Eley, T., 1 Jun 2015, In: Journal of the American Academy of Child and Adolescent Psychiatry. 54, 6, p. 454–463

    Research output: Contribution to journalArticlepeer-review

  16. Response to pinta

    Keers, R., 1 Jul 2014, In: The American Journal of Psychiatry. 171, 7, p. 797-797 1 p.

    Research output: Contribution to journalLetterpeer-review

  17. The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder

    Malki, K., Keers, R., Tosto, M. G., Lourdusamy, A., Carboni, L., Domenici, E., Uher, R., McGuffin, P. & Schalkwyk, L. C., 7 May 2014, (E-pub ahead of print) In: BMC Medicine. 12, 14 p., 73.

    Research output: Contribution to journalArticlepeer-review

  18. Genetic predictors of antidepressant side effects: A grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

    Hodgson, K., Uher, R., Crawford, A. A., Lewis, G., O'Donovan, M. C., Keers, R., Dernovsek, M. Z., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Aitchison, K., Farmer, A., Davis, O. & McGuffin, P., Feb 2014, In: Journal of Psychopharmacology. 28, 2, p. 142-150 9 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  19. Association of Violence With Emergence of Persecutory Delusions in Untreated Schizophrenia

    Keers, R., Ullrich, S., Destavola, B. L. & Coid, J. W., 13 Nov 2013, (E-pub ahead of print) In: The American Journal of Psychiatry. N/A, N/A, p. N/A 8 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  20. Estimating the heritability of reporting stressful life events captured by common genetic variants

    Power, R. A., Wingenbach, T., Cohen-Woods, S., Uher, R., Ng, M. Y., Butler, A. W., Ising, M., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Zobel, A., Mors, O., Placentino, A., Rietschel, M., Lucae, S., & 14 othersHolsboer, F., Binder, E. B., Keers, R., Tozzi, F., Muglia, P., Breen, G., Craig, I. W., Mueller-Myhsok, B., Kennedy, J. L., Strauss, J., Vincent, J. B., Lewis, C. M., Farmer, A. E. & McGuffin, P., Sep 2013, In: Psychological Medicine. 43, 9, p. 1965-1971 7 p.

    Research output: Contribution to journalArticlepeer-review

  21. Gang Membership, Violence, and Psychiatric Morbidity

    Coid, J. W., Ullrich, S., Keers, R., Bebbington, P., Destavola, B. L., Kallis, C., Yang, M., Reiss, D., Jenkins, R. & Donnelly, P., 12 Jul 2013, (E-pub ahead of print) In: The American Journal of Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  22. The relationship between delusions and violence: findings from the East London first episode psychosis study

    Coid, J. W., Ullrich, S., Kallis, C., Keers, R., Barker, D., Cowden, F. & Stamps, R., May 2013, In: JAMA Psychiatry. 70, 5, p. 465-71 7 p.

    Research output: Contribution to journalArticlepeer-review

  23. The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression

    Power, R. A., Lecky-Thompson, L., Fisher, H. L., Cohen-Woods, S., Hosang, G. M., Uher, R., Powell-Smith, G., Keers, R., Tropeano, M., Korszun, A., Jones, L., Jones, I., Owen, M. J., Craddock, N., Craig, I. W., Farmer, A. E. & McGuffin, P., 22 Apr 2013, In: Journal of Psychiatric Research. 47, 8, p. 1032-1035 4 p.

    Research output: Contribution to journalArticlepeer-review

  24. Delusions, Anger, and Serious Violence: New Findings From the MacArthur Violence Risk Assessment Study

    Ullrich, S., Keers, R. & Coid, J. W., 2013, (E-pub ahead of print) In: Schizophrenia Bulletin. N/A, N/A, p. N/A 8 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  25. Will gene-environment interactions explain differential antidepressant response?

    Keers, R., May 2012, In: Personalized Medicine. 9, 3, p. 319-322 4 p., N/A.

    Research output: Contribution to journalEditorialpeer-review

  26. Gene-environment interaction in major depression and antidepressant treatment response

    Keers, R. & Uher, R., Apr 2012, In: CURRENT PSYCHIATRY REPORTS. 14, 2, p. 129 - 137 9 p.

    Research output: Contribution to journalArticlepeer-review

  27. Variation in GNB3 predicts response and adverse reactions to antidepressants

    Keers, R., Bonvicini, C., Scassellati, C., Uher, R., Placentino, A., Giovannini, C., Rietschel, M., Henigsberg, N., Kozel, D., Mors, O., Maier, W., Hauser, J., Souery, D., Mendlewicz, J., Schmäl, C., Zobel, A., Larsen, E. R., Szczepankiewicz, A., Kovacic, Z., Elkin, A., & 5 othersCraig, I., McGuffin, P., Farmer, A. E., Aitchison, K. J. & Gennarelli, M., Jul 2011, In: Journal of Psychopharmacology. 25, 7, p. 867 - 874 8 p.

    Research output: Contribution to journalArticlepeer-review

  28. Changes in body weight during pharmacological treatment of depression

    Uher, R., Mors, O., Hauser, J., Rietschel, M., Maier, W., Kozel, D., Henigsberg, N., Souery, D., Placentino, A., Keers, R., Gray, J. M., Dernovsek, M. Z., Strohmaier, J., Larsen, E. R., Zobel, A., Szczepankiewicz, A., Kalember, P., Mendlewicz, J., Aitchison, K. J., McGuffin, P., & 1 othersFarmer, A., Apr 2011, In: International Journal of Neuropsychopharmacology . 14, 3, p. 367 - 375 9 p.

    Research output: Contribution to journalArticlepeer-review

  29. Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project

    Keers, R., Uher, R., Huezo-Diaz, P., Smith, R., Jaffee, S., Rietschel, M., Henigsberg, N., Kozel, D., Mors, O., Maier, W., Zobel, A., Hauser, J., Souery, D., Placentino, A., Larsen, E. R., Dmitrzak-Weglarz, M., Gupta, B., Hoda, F., Craig, I., McGuffin, P., & 2 othersFarmer, A. E. & Aitchison, K. J., Apr 2011, In: PHARMACOGENOMICS JOURNAL. 11, 2, p. 138 - 145 8 p.

    Research output: Contribution to journalArticlepeer-review

  30. Pharmacogenetics of antidepressant response

    Keers, R. & Aitchison, K. J., Jan 2011, In: Expert Review of Neurotherapeutics. 11, 1, p. 101 - 125 25 p.

    Research output: Contribution to journalArticlepeer-review

  31. Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP

    Keers, R., Uher, R., Gupta, B., Rietschel, M., Schulze, T. G., Hauser, J., Skibinska, M., Henigsberg, N., Kalember, P., Maier, W., Zobel, A., Mors, O., Kristensen, A. S., Kozel, D., Giovannini, C., Mendlewicz, J., Kumar, S., McGuffin, P., Farmer, A. E. & Aitchison, K. J., Dec 2010, In: Journal of Affective Disorders. 127, 1-3, p. 337 - 342 6 p.

    Research output: Contribution to journalArticlepeer-review

  32. Gender differences in antidepressant drug response

    Keers, R. & Aitchison, K. J., Oct 2010, In: International Review of Psychiatry. 22, 5, p. 485 - 500 16 p.

    Research output: Contribution to journalArticlepeer-review

  33. Selected summaries from the XVII World Congress of Psychiatric Genetics, San Diego, California, USA, 4-8 November 2009

    Amstadter, A. B., Balachandar, V., Bergen, S. E., Ceulemans, S., Christensen, J. H., Cole, J., Dagdan, E., De Luca, V., Ducci, F., Tee, S. F., Hartz, S., Keers, R., Medland, S., Melas, P. A., Mühleisen, T. W., Ozomaro, U., Pidsley, R., Scott, A. P., Sha, L., Talati, A., & 5 othersTeltsh, O., Videtic, A., Wang, K., Wong, C. & Delisi, L. E., Oct 2010, In: Psychiatric Genetics. 20, 5, p. 229-68 40 p.

    Research output: Contribution to journalArticlepeer-review

  34. Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorder

    Hosang, G. M., Uher, R., Keers, R., Cohen-Woods, S., Craig, I., Korszun, A., Perry, J., Tozzi, F., Muglia, P., McGuffin, P. & Farmer, A. E., Sep 2010, In: Journal of Affective Disorders. 125, 1-3, p. 345 - 349 5 p.

    Research output: Contribution to journalArticlepeer-review

  35. Extracting a needle from a haystack: reanalysis of whole genome data reveals a readily translatable finding

    Keers, R., Farmer, A. E. & Aitchison, K. J., Aug 2009, In: Psychological Medicine. 39, 8, p. 1231 - 1235 5 p.

    Research output: Contribution to journalArticlepeer-review

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