Ruth Bowyer

2025

ESPClust: Unsupervised identification of modifiers for the effect size profile in omics association studies

Pérez-Reche, F. J., Cheetham, N. J., Bowyer, R. C. E., Thompson, E. J., Tettamanzi, F., Menni, C. & Steves, C. J., 6 Feb 2025, (E-pub ahead of print) In: BIOINFORMATICS. 41, 2, btaf065.

Research output: Contribution to journal › Article › peer-review

Open Access

Longitudinal association of Perfluorooctanoic Acid (PFOA) and Perfluorooctanesulphonic Acid (PFOS) exposure with lipid traits, in a healthy unselected population

Raza, Y., El-Sayed Moustafa, J., Zhang, X., Wang, D., Tomlinson, M., Falchi, M., Menni, C., Bowyer, R., Steves, C. & Small, K., 4 Apr 2025, (Accepted/In press) In: Journal of Exposure Science and Environmental Epidemiology.

Research output: Contribution to journal › Article › peer-review

Open Access

Social determinants of recovery from ongoing symptoms following COVID-19 in two UK longitudinal studies: a prospective cohort study

COVID Symptom Study Biobank Consortium, 21 Mar 2025, In: BMJ Public Health. 3, 1, p. e001166

Research output: Contribution to journal › Article › peer-review

2024

Effect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised controlled trial

Ni Lochlainn, M., Bowyer, R. C. E., Moll, J. M., García, M. P., Wadge, S., Baleanu, A. F., Nessa, A., Sheedy, A., Akdag, G., Hart, D., Raffaele, G., Seed, P. T., Murphy, C., Harridge, S. D. R., Welch, A. A., Greig, C., Whelan, K. & Steves, C. J., 29 Feb 2024, In: Nature Communications. 15, 1, 1859.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Citations (Scopus)

2023

Antibody levels following vaccination against SARSCoV-2: associations with post-vaccination infection and risk factors in two UK longitudinal studies

Cheetham, N. J., Kibble, M., Wong, A., Silverwood, R. J., Knuppel, A., Williams, D. M., Hamilton, O. K. L., Lee, P. H., Staatz, C. B., Di Gessa, G., Zhu, J., Katikireddi, S. V., Ploubidis, G. B., Thompson, E. J., Bowyer, R. C. E., Zhang, X., Abbasian, G., Garcia, M. P., Hart, D. & Seow, J. & 17 others, Graham, C., Kouphou, N., Acors, S., Malim, M. H., Mitchell, R. E., Northstone, K., Major-Smith, D., Matthews, S., Breeze, T., Crawford, M., Molloy, L., Kwong, A. S. F., Doores, K. J., Chaturvedi, N., Duncan, E. L., Timpson, N. J. & Steves, C. J., 2023, In: eLife. 12, e80428.

Research output: Contribution to journal › Article › peer-review

Open Access

File

14 Citations (Scopus)

127 Downloads (Pure)

Characterising patterns of COVID-19 and long COVID symptoms: evidence from nine UK longitudinal studies

Bowyer, R. C. E., Huggins, C., Toms, R., Shaw, R. J., Hou, B., Thompson, E. J., Kwong, A. S. F., Williams, D. M., Kibble, M., Ploubidis, G. B., Timpson, N. J., Sterne, J. A. C., Chaturvedi, N., Steves, C. J., Tilling, K. & Silverwood, R. J., 1 Feb 2023, In: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 38, 2, p. 199-210 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (Scopus)

Higher dietary protein intake is associated with sarcopenia in older British twins

Ni Lochlainn, M., Bowyer, R., Welch, A., Whelan, K. & Steves, C., 3 Jan 2023, (Accepted/In press) In: Age and Ageing.

Research output: Contribution to journal › Article › peer-review

Open Access

File

52 Downloads (Pure)

Host Genotype Links to Salivary and Gut Microbiota by Periodontal Status

Kurushima, Y., Wells, P. M., Bowyer, R. C. E., Zoheir, N., Doran, S., Richardson, J. P., Sprockett, D. D., Relman, D. A., Steves, C. J. & Nibali, L., 1 Feb 2023, In: Journal of Dental Research. 102, 2, p. 146-156

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

PPI-Induced Changes in Plasma Metabolite Levels Influence Total Hip Bone Mineral Density in a UK Cohort

Zhang, X., Adebayo, A., Wang, D., Raza, Y., Tomlinson, M., Dooley, H., Bowyer, R., Small, K., Steves, C., Spector, T., Duncan, E., Visconti, A. & Falchi, M., Feb 2023, In: Journal of Bone and Mineral Research. 38, 2, p. 326-334 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

2022

Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans

Roberts, A., Morea, A., Amar, A., Zito, A., El-Sayed Moustafa, J., Tomlinson, M., Bowyer, R., Zhang, X., Christiansen, C., de Oliveira Costeira, R. C., Steves, C., Mangino, M., Bell, J., Wong, C., Vyse, T. & Small, K., 22 Nov 2022, In: eLife. 11

Research output: Contribution to journal › Article › peer-review

Open Access

13 Citations (Scopus)

Characterisation, procedures and heritability of acute dietary intake in the Twins UK cohort: an observational study

Leeming, E. R., Mompeo, O., Turk, P., Bowyer, R. C. E., Louca, P., Johnson, A. J., Spector, T. D., Le Roy, C. & Gibson, R., 27 Feb 2022, (E-pub ahead of print) In: Nutrition Journal. 21, 1, 13.

Research output: Contribution to journal › Article › peer-review

Open Access

File

3 Citations (Scopus)

183 Downloads (Pure)

Impacts of dietary exposure to pesticides on faecal microbiome metabolism in adult twins

Mesnage, R., Bowyer, R. C. E., El Balkhi, S., Saint-Marcoux, F., Gardere, A., Ducarmon, Q. R., Geelen, A. R., Zwittink, R. D., Tsoukalas, D., Sarandi, E., Paramera, E. I., Spector, T., Steves, C. J. & Antoniou, M. N., Dec 2022, In: Environmental Health: A Global Access Science Source. 21, 1, 46.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (Scopus)

Individual Factors Including Age, BMI, and Heritable Factors Underlie Temperature Variation in Sickness and in Health: An Observational, Multi-cohort Study

GSTT Covid Collaborative , Penfold, R. S., Zazzara, M. B., Österdahl, M. F., Welch, C., Ni Lochlainn, M., Freidin, M. B., Bowyer, R. C. E., Thompson, E. J., Antonelli, M., Tan, Y. X. R., Sudre, C. H., Modat, M., Murray, B., Wolf, J., Ourselin, S., Veenith, T., Lord, J. M. & Steves, C. J., Sept 2022, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 77, 9, p. 1890-1897 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records

Thompson, E. J., Williams, D. M., Walker, A. J., Mitchell, R. E., Niedzwiedz, C. L., Yang, T. C., Huggins, C. F., Kwong, A. S. F., Silverwood, R. J., Di Gessa, G., Bowyer, R., Northstone, K., Hou, B., Green, M. J., Dodgeon, B., Doores, K., Duncan, E., Williams, F., Steptoe, A. & Porteous, D. J. & 11 others, McEachan, R. R. C., Tomlinson, L., Goldacre, B., Patalay, P., Ploubidis, G. B., Katikireddi, S. V., Tilling, K., Rentsch, C. T., Timpson, N. J., Chaturvedi, N. & Steves, C., 28 Jun 2022, (E-pub ahead of print) In: Nature Communications. 13, 1, 1 p., 3528.

Research output: Contribution to journal › Article › peer-review

Open Access

329 Citations (Scopus)

Mental and social wellbeing and the UK coronavirus job retention scheme: Evidence from nine longitudinal studies

Wels, J., Booth, C., Wielgoszewska, B., Green, M. J., Di Gessa, G., Huggins, C. F., Griffith, G. J., Kwong, A. S. F., Bowyer, R. C. E., Maddock, J., Patalay, P., Silverwood, R. J., Fitzsimons, E., Shaw, R. J., Thompson, E. J., Steptoe, A., Hughes, A., Chaturvedi, N., Steves, C. & Katikireddi, S. V. & 1 others, Ploubidis, G. B., 3 Aug 2022, In: Social Sciences & Medicine. 308, 9 p., 115226.

Research output: Contribution to journal › Article › peer-review

Open Access

File

19 Citations (Scopus)

352 Downloads (Pure)

Microbiota composition is moderately associated with greenspace composition in a UK cohort of twins

Bowyer, R., Twohig-Bennett, C., Coombes, E., Wells, P., Spector, T., Jones, A. & Steves, C., 20 Mar 2022, In: Science of the Total Environment. 813, 152321.

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Psychological distress, depression, anxiety and life satisfaction following COVID-19 infection: Evidence from 11 UK longitudinal population studies

Thompson, E. J., Stafford, J., Moltrecht, B., Huggins, C. F., Kwong, A. S. F., Shaw, R. J., Zaninotto, P., Patel, K., Silverwood, R. J., McElroy, E., Pierce, M., Green, M. J., Bowyer, R., Maddock, J., Tilling, K., Katikireddi, S. V., Ploubidis, G. B., Porteous, D. J., Timpson, N. J. & Chaturvedi, N. & 2 others, Steves, C. & Patalay, P., 14 Oct 2022, In: The Lancet Psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Citations (Scopus)

Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome

Le Roy, C. I., Kurilshikov, A., Leeming, E. R., Visconti, A., Bowyer, R. C. E., Menni, C., Falchi, M., Koutnikova, H., Veiga, P., Zhernakova, A., Derrien, M. & Spector, T. D., Dec 2022, In: BMC Microbiology. 22, 1, p. 39 1 p., 39.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Citations (Scopus)

2021

Attributes and predictors of long COVID

Sudre, C. H., Murray, B., Varsavsky, T., Graham, M. S., Penfold, R. S., Bowyer, R. C., Pujol, J. C., Klaser, K., Antonelli, M., Canas, L. S., Molteni, E., Modat, M., Jorge Cardoso, M., May, A., Ganesh, S., Davies, R., Nguyen, L. H., Drew, D. A., Astley, C. M. & Joshi, A. D. & 13 others, Merino, J., Tsereteli, N., Fall, T., Gomez, M. F., Duncan, E. L., Menni, C., Williams, F. M. K., Franks, P. W., Chan, A. T., Wolf, J., Ourselin, S., Spector, T. & Steves, C. J., Apr 2021, In: Nature Medicine. 27, 4, p. 626-631 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1649 Citations (Scopus)

Cancer and Risk of COVID-19 Through a General Community Survey

COPE Consortium, Jan 2021, In: ONCOLOGIST. 26, 1, ONCO13497.

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Diagnostic value of cutaneous manifestation of SARS-CoV-2 infection

Visconti, A., Bataille, V., Rossi, N., Kluk, J., Murphy, R., Puig, S., Nambi, R., Bowyer, R. C. E., Murray, B., Bournot, A., Wolf, J., Ourselin, S., Steves, C. J., Spector, T. D. & Falchi, M., May 2021, In: The British journal of dermatology. 184, 5, p. 880-887 8 p.

Research output: Contribution to journal › Article › peer-review

File

39 Citations (Scopus)

115 Downloads (Pure)

Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445 850 users of the COVID-19 Symptom Study app

Louca, B., Murray, B., Klaser, K., Graham, M., Mazidi, M., Leeming, E., Thompson, E. J., Bowyer, R., Drew, D. A., Nguyen, H.-L., Merino, J., Gomez, M. F., Mompeo Masachs, O., de Oliveira Costeira, R. C., Sudre, C. H., Gibson, R., Steves, C., Wolf, J., Franks, P. W. & Ourselin, S. & 6 others, Chan, A. T., Berry, S., Valdes, A. M., Calder, P. C., Spector, T. & Menni, C., 1 Jun 2021, In: BMJ Nutrition, Prevention and Health. 4, 1, p. 149-157 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

100 Citations (Scopus)

Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults

Zazzara, M. B., Penfold, R. S., Roberts, A. L., Lee, K. A., Dooley, H., Sudre, C. H., Welch, C., Bowyer, R. C. E., Visconti, A., Mangino, M., Freidin, M. B., El-sayed Moustafa, J. S., Small, K. S., Murray, B., Modat, M., Graham, M. S., Wolf, J., Ourselin, S., Martin, F. C. & Steves, C. J. & 1 others, Lochlainn, M. N., 8 Jan 2021, In: Age and Ageing. 50, 1, p. 40-48 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

83 Citations (Scopus)

166 Downloads (Pure)

Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults

Zazzara, M. B., Penfold, R. S., Roberts, A. L., Lee, K. A., Dooley, H., Sudre, C. H., Welch, C., Bowyer, R. C. E., Visconti, A., Mangino, M., Freidin, M. B., El-Sayed Moustafa, J. S., Small, K. S., Murray, B., Modat, M., Graham, M. S., Wolf, J., Ourselin, S., Martin, F. C. & Steves, C. J. & 1 others, Lochlainn, M. N., 8 Jan 2021, In: Age and Ageing. 50, 1, p. 40-48 9 p.

Research output: Contribution to journal › Article › peer-review

Self-Reported Symptoms of COVID-19, Including Symptoms Most Predictive of SARS-CoV-2 Infection, Are Heritable

Williams, F. M. K., Freidin, M. B., Mangino, M., Couvreur, S., Visconti, A., Bowyer, R. C. E., Le Roy, C. I., Falchi, M., Mompeó, O., Sudre, C., Davies, R., Hammond, C., Menni, C., Steves, C. J. & Spector, T. D., 9 Feb 2021, (E-pub ahead of print) In: TWIN RESEARCH AND HUMAN GENETICS. 23, 6, p. 316-321 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Citations (Scopus)

Symptom clusters in COVID-19: A potential clinical prediction tool from the COVID Symptom Study app

Sudre, C. H., Lee, K. A., Lochlainn, M. N., Varsavsky, T., Murray, B., Graham, M. S., Menni, C., Modat, M., Bowyer, R. C. E., Nguyen, L. H., Drew, D. A., Joshi, A. D., Ma, W., Guo, C.-G., Lo, C.-H., Ganesh, S., Buwe, A., Pujol, J. C., du Cadet, J. L. & Visconti, A. & 13 others, Freidin, M. B., El-Sayed Moustafa, J. S., Falchi, M., Davies, R., Gomez, M. F., Fall, T., Cardoso, M. J., Wolf, J., Franks, P. W., Chan, A. T., Spector, T. D., Steves, C. J. & Ourselin, S., 19 Mar 2021, In: Science Advances. 7, 12, eabd4177.

Research output: Contribution to journal › Article › peer-review

Open Access

97 Citations (Scopus)

The composition of the gut microbiome differs among community dwelling older people with good and poor appetite

Cox, N. J., Bowyer, R. C. E., Ni Lochlainn, M., Wells, P. M., Roberts, H. C. & Steves, C. J., Apr 2021, In: Journal of Cachexia, Sarcopenia and Muscle. 12, 2, p. 368-377 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Citations (Scopus)

TwinsUK COVID-19 personal experience questionnaire (CoPE): wave 1 data capture April-May 2020

Suthahar, A., Hart, D., Bowyer, R., Thompson, E. J. & Steves, C., 20 May 2021, In: Wellcome Open Research. p. 1 10 p.

Research output: Contribution to journal › Article › peer-review

2020

An association between chronic widespread pain and the gut microbiome

Freidin, M., Stalteri, M., Wells, P., Lachance, G., Baleanu, A.-F., Bowyer, R., Kurilshikov, A., Zhernakova, A., Steves, C. & Williams, F., 12 Nov 2020, (Accepted/In press) In: Rheumatology (Oxford, England).

Research output: Contribution to journal › Article › peer-review

Associations between gut microbiota and genetic risk for rheumatoid arthritis in the absence of disease: a cross-sectional study

Wells, P. M., Adebayo, A. S., Bowyer, R. C. E., Freidin, M. B., Finckh, A., Strowig, T., Lesker, T. R., Alpizar-Rodriguez, D., Gilbert, B., Kirkham, B., Cope, A. P., Steves, C. J. & Williams, F. M. K., Jul 2020, In: The Lancet Rheumatology. 2, 7, p. e418-e427

Research output: Contribution to journal › Article › peer-review

Open Access

122 Citations (Scopus)

Associations between UK tap water and gut microbiota composition suggest the gut microbiome as a potential mediator of health differences linked to water quality

Bowyer, R. C. E., Schillereff, D. N., Jackson, M., Le Roy, C. I., Wells, P. M., Spector, T. D. & Steves, C. J., 23 May 2020, (Accepted/In press) In: Science of the Total Environment.

Research output: Contribution to journal › Article › peer-review

Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sample from SE England

Wells, P. M., Doores, K. J., Couvreur, S., Nunez, R. M., Seow, J., Graham, C., Acors, S., Kouphou, N., Neil, S. J. D., Tedder, R. S., Matos, P. M., Poulton, K., Lista, M. J., Dickenson, R. E., Sertkaya, H., Maguire, T. J. A., Scourfield, E. J., Bowyer, R. C. E., Hart, D. & O'Byrne, A. & 11 others, Steel, K. J. A., Hemmings, O., Rosadas, C., McClure, M. O., Capedevilla-pujol, J., Wolf, J., Ourselin, S., Brown, M. A., Malim, M. H., Spector, T. & Steves, C. J., Dec 2020, In: Journal of Infection. 81, 6, p. 931-936 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Citations (Scopus)

Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

Nag, A., Kurushima, Y., Bowyer, R. C. E., Wells, P. M., Weiss, S., Pietzner, M., Kocher, T., Raffler, J., Völker, U., Mangino, M., Spector, T. D., Milburn, M. V., Kastenmüller, G., Mohney, R. P., Suhre, K., Menni, C. & Steves, C. J., 27 Mar 2020, In: Human Molecular Genetics. 29, 5, p. 864-875 12 p., ddz308.

Research output: Contribution to journal › Article › peer-review

Open Access

File