Samantha Terry

Dr

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    Personal profile

    Biographical details

    I am a Reader in Radiobiology at King's College London and have in the past worked as a

    • Postdoctoral researcher at King's College London (radionuclide imaging of multiple myeloma)
    • Roche postdoctoral fellow at the Radboud UMC, the Netherlands (radionuclide imaging of tumour microenvironment and arthritis)
    • Postdoctoral researcher at University of Oxford (targeted radionuclide therapy and the effect of chromatin density)
    • PhD student at the University of St Andrews (how chromosomes are damaged after external beam irradiation)

    My thesis can be viewed at https://research-repository.st-andrews.ac.uk/bitstream/10023/873/6/Samantha%20Terry%20PhD%20thesis.pdf

     

    Research interests

    My research focusses on determining how radionuclides used for therapy affect either the cells they are targeting or off-target cells in order to determine how we can best use these radionuclides. My work is mostly in vitro and preclinical, with some aspects of clinical translation. Questions that I would like to answer for a whole range of radionuclides, including those used in imaging, are:

    • How can therapeutic radionuclides be used to maximize tumour cell kill for the same amount of radioactivity whilst minimizing damage to healthy tissues?
    • How important is subcellular localisation?
    • Are radionuclides more effective in metastases?
    • Does bystander play a role in radionuclide therapy?
    • How can radionuclides be made more effective, in terms of combination therapies?
    • Are different cells more sensitive to certain types of radiation than others?

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    • SDG 3 - Good Health and Well-being

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