King's College London

Research portal

Dr Sarah Salvage

  1. Inhibition of i-NOS but not n-NOS protects rat primary cell cultures against MPP+-induced neuronal toxicity

    Brzozowski, M. J., Jenner, P. & Rose, S., 1 Jun 2015, In : Journal of Neural Transmission. 122, 6, p. 779-788 9 p., 10.1007/s00702-014-1334-8.

    Research output: Contribution to journalArticle

  2. The H3receptor agonist immepip does not affect l-dopa-induced abnormal involuntary movements in 6-OHDA-lesioned rats

    Papathanou, M., Jenner, P., Iravani, M. M., Jackson, M. J., Stockwell, K. A., Strang, I., Zeng, B. Y., McCreary, A. & Rose, S., 15 Oct 2014, In : European Journal of Pharmacology. 741, p. 304-310 7 p., 00142999.

    Research output: Contribution to journalArticle

  3. Overexpression of corticotropin releasing factor in the central nucleus of the amygdala advances puberty and disrupts reproductive cycles in female rats

    Li, X. F., Hu, M. H., Li, S. Y., Geach, C., Hikima, A., Rose, S., Greenwood, M. P., Greenwood, M., Murphy, D., Poston, L., Lightman, S. L. & O'Byrne, K. T., Oct 2014, In : Endocrinology. 155, 10, p. 3934-44 11 p.

    Research output: Contribution to journalArticle

  4. Proteomic Analysis of Striatum from MPTP-Treated Marmosets (Callithrix jacchus) with L-DOPA-Induced Dyskinesia of Differing Severity

    Hurley, M. J., Jackson, M. J., Smith, L. A., Rose, S. & Jenner, P., Feb 2014, In : Journal of Molecular Neuroscience. 52, 2, p. 302-312 11 p.

    Research output: Contribution to journalArticle

  5. Design, synthesis and biological evaluation of peptide derivatives of L-dopa as anti-parkinsonian agents

    Zhou, T., Hider, R. C., Jenner, P., Campbell, B., Hobbs, C. J., Rose, S., Jairaj, M., Tayarani-Binazir, K. A. & Syme, A., 1 Oct 2013, In : BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 23, 19, p. 5279-5282 4 p., N/A.

    Research output: Contribution to journalArticle

  6. Levodopa infusion does not decrease the onset of abnormal involuntary movements in parkinsonian rats

    Papathanou, M., van der Laan, R., Jenner, P., Rose, S. & McCreary, A. C., Jul 2013, In : Movement Disorders. 28, 8, p. 1072-1079 8 p., N/A.

    Research output: Contribution to journalArticle

  7. Effect and Mechanism of Acupuncture on Alzheimer's Disease

    Zeng, B. Y., Salvage, S. & Jenner, P., 2013, In : International Review of Neurobiology. 111, p. 181-195 15 p.

    Research output: Contribution to journalArticle

  8. Differential Toxicity of 6-Hydroxydopamine in SH-SY5Y Human Neuroblastoma Cells and Rat Brain Mitochondria: Protective Role of Catalase and Superoxide Dismutase

    Iglesias-Gonzalez, J., Sanchez-Iglesias, S., Mendez-Alvarez, E., Rose, S., Hikima, A., Jenner, P. & Soto-Otero, R., Oct 2012, In : Neurochemical Research. 37, 10, p. 2150-2160 11 p.

    Research output: Contribution to journalArticle

  9. Benserazide dosing regimen affects the response to L-3,4-dihydroxyphenylalanine in the 6-hydroxydopamine-lesioned rat

    Tayarani-Binazir, K. A., Jackson, M. J., Strang, I., Jairaj, M., Rose, S. & Jenner, P., Apr 2012, In : Behavioural Pharmacology. 23, 2, p. 126 - 133 8 p.

    Research output: Contribution to journalArticle

  10. Lipopolysaccharide-induced nigral inflammation leads to increased IL-1 beta tissue content and expression of astrocytic glial cell line-derived neurotrophic factor

    Iravani, M. M., Sadeghian, M., Leung, C. C. M., Jenner, P. & Rose, S., 29 Feb 2012, In : Neuroscience Letters. 510, 2, p. 138 - 142 5 p.

    Research output: Contribution to journalArticle

  11. The effect of nNOS inhibitors on toxin-induced cell death in dopaminergic cell lines depends on the extent of enzyme expression

    Brzozowski, M. J., Alcantara, S. L., Iravani, M. M., Rose, S. & Jenner, P., 2 Aug 2011, In : Brain Research. 1404, p. 21 - 30 10 p.

    Research output: Contribution to journalArticle

  12. A major metabolite of bupropion reverses motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets

    Hansard, M. J., Jackson, M. J., Smith, L. A., Rose, S. & Jenner, P., Jun 2011, In : Behavioural Pharmacology. 22, 3, p. 269 - 274 6 p.

    Research output: Contribution to journalArticle

  13. Induction and expression of abnormal involuntary movements is related to the duration of dopaminergic stimulation in 6-OHDA-lesioned rats

    Papathanou, M., Rose, S., McCreary, A. & Jenner, P., Jun 2011, In : European Journal of Neuroscience. 33, 12, p. 2247 - 2254 8 p.

    Research output: Contribution to journalArticle

  14. Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia

    Zeng, B-Y., Iravani, M. M., Jackson, M. J., Rose, S., Parent, A. & Jenner, P., Dec 2010, In : Neurobiology of Disease. 40, 3, p. 599 - 607 9 p.

    Research output: Contribution to journalArticle

  15. Pardoprunox Reverses Motor Deficits but Induces Only Mild Dyskinesia in MPTP-Treated Common Marmosets

    Johnston, L. C., Jackson, M. J., Rose, S., McCreary, A. C. & Jenner, P., 15 Oct 2010, In : Movement Disorders. 25, 13, p. 2059 - 2066 8 p.

    Research output: Contribution to journalArticle

  16. The effects of dose and route of administration of PSI on behavioural and biochemical indices of neuronal degeneration in the rat brain

    Bukhatwa, S., Zeng, B-Y., Rose, S. & Jenner, P., 1 Oct 2010, In : Brain Research. 1354, p. 236 - 242 7 p.

    Research output: Contribution to journalArticle

  17. Design, synthesis and biological evaluation of L-dopa amide derivatives as potential prodrugs for the treatment of Parkinson's disease

    Zhou, T., Hider, R. C., Jenner, P., Campbell, B., Hobbs, C. J., Rose, S., Jairaj, M., Tayarani-Binazir, K. A. & Syme, A., Sep 2010, In : EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 45, 9, p. 4035 - 4042 8 p.

    Research output: Contribution to journalArticle

  18. Pramipexole Combined with Levodopa Improves Motor Function but Reduces Dyskinesia in MPTP-Treated Common Marmosets

    Tayarani-Binazir, K. A., Jackson, M. J., Rose, S., Olanow, C. W. & Jenner, P., 15 Feb 2010, In : Movement Disorders. 25, 3, p. 377 - 384 8 p.

    Research output: Contribution to journalArticle

  19. Expression of catechol-O-methyltransferase in the brain and periphery of normal and MPTP-treated common marmosets

    Zeng, B-Y., Balfour, R. H., Jackson, M. J., Rose, S. & Jenner, P., Jan 2010, In : Journal of Neural Transmission. 117, 1, p. 45 - 51 7 p.

    Research output: Contribution to journalArticle

  20. An immunohistochemical and stereological analysis of PSI-induced nigral neuronal degeneration in the rat

    Bukhatwa, S., Iravani, M. M., Zeng, B-Y., Cooper, J. D., Rose, S. & Jenner, P., Apr 2009, In : Journal of Neurochemistry. 109, 1, p. 52 - 59 8 p.

    Research output: Contribution to journalArticle

  21. Continuous delivery of ropinirole reverses motor deficits without dyskinesia induction in MPTP-treated common marmosets

    Stockwell, K., Virley, DJ., Perren, M., Iravani, M., Jackson, MJ., Rose, S. & Jenner, P., May 2008, In : Experimental Neurology. 211, 1, p. 172-179 8 p.

    Research output: Contribution to journalArticle

  22. The novel adenosine A(2a) receptor antagonist ST1535 potentiates the effects of a threshold dose of L-DOPA in MPTP treated common marmosets

    Rose, S., Jackson, M. J., Smith, L. A., Stockwell, K., Johnson, L., Carminati, P. & Jenner, P., 28 Sep 2006, In : European Journal of Pharmacology. 546, 1-3, p. 82 - 87 6 p.

    Research output: Contribution to journalArticle

  23. Reproducible nigral cell loss after systemic proteasomal inhibitor administration to rats

    Zeng, B. Y., Bukhatwa, S., Hikima, A., Rose, S. & Jenner, P., Aug 2006, In : Annals of Neurology. 60, 2, p. 248 - 252 5 p.

    Research output: Contribution to journalArticle

  24. MPTP treatment of common marmosets impairs proteasomal enzyme activity and decreases expression of structural and regulatory elements of the 26S proteasome

    Zeng, B. Y., Iravani, M. M., Lin, S. T., Irifune, M., Kuoppamaki, M., Al-Barghouthy, G., Smith, L., Jackson, M. J., Rose, S., Medhurst, A. D. & Jenner, P., Apr 2006, In : European Journal of Neuroscience. 23, 7, p. 1766 - 1774 9 p.

    Research output: Contribution to journalArticle

  25. 3-Nitrotyrosine-dependent dopaminergic neurotoxicity following direct nigral administration of a peroxynitrite but not a nitric oxide donor

    Iravani, M. M., Haddon, C. O., Rose, S. & Jenner, P., 5 Jan 2006, In : Brain Research. 1067, 1, p. 256 - 262 7 p.

    Research output: Contribution to journalArticle

  26. Lipophilicity plays a major role in modulating the inhibition of monoamine oxidase B by 7-substituted coumarins

    Carotti, A., Altomare, C., Catto, M., Gnerre, C., Summo, L., De Marco, A., Rose, S., Jenner, P. & Testa, B., 2006, In : CHEMISTRY & BIODIVERSITY. 3, 2, p. 134 - 149 16 p.

    Research output: Contribution to journalArticle

  27. Osteopontin expression in substantia nigra in MPTP-treated primates and in Parkinson's disease

    Iczkiewicz, J., Jackson, M. J., Smith, L. A., Rose, S. & Jenner, P., 2006, In : Brain Research. 1118, p. 239 - 250 12 p.

    Research output: Contribution to journalArticle

  28. Age-associated changes in protein oxidation and proteasome activities in rat brain: Modulation by antioxidants

    El Mohsen, M. M. A., Iravani, M. M., Spencer, J. P. E., Rose, S., Fahim, A. T., Motawi, T. M. K., Ismail, N. A. F. & Jenner, P., 21 Oct 2005, In : Biochemical and Biophysical Research Communications. 336, 2, p. 386 - 391 6 p.

    Research output: Contribution to journalArticle

  29. The acute and the long-term effects of nigral lipopolysaccharide administration on dopaminergic dysfunction and glial cell activation

    Iravani, M. M., Leung, C. C. M., Sadeghian, M., Haddon, C. O., Rose, S. & Jenner, P., Jul 2005, In : European Journal of Neuroscience. 22, 2, p. 317 - 330 14 p.

    Research output: Contribution to journalArticle

  30. Immunoautoradiographic analysis of NMDA receptor subunits and associated postsynaptic density proteins in the brain of dyskinetic MPTP-treated common marmosets

    Hurley, M. J., Jackson, M. J., Smith, L. A., Rose, S. & Jenner, P., Jun 2005, In : European Journal of Neuroscience. 21, 12, p. 3240 - 3250 11 p.

    Research output: Contribution to journalArticle

  31. Proteasomal activity in brain differs between species, and brain regions and changes with age

    Zeng, B. Y., Medhurst, A. D., Jackson, M., Rose, S. & Jenner, P., Jun 2005, In : Mechanisms of Ageing and Development. 126, 6-7, p. 760 - 766 7 p.

    Research output: Contribution to journalArticle

  32. Increased osteopontin expression following intranigral lipopolysaccharide injection in the rat.

    Iczkiewicz, J., Rose, S. & Jenner, P., Apr 2005, In : European Journal of Neuroscience. 21, 7, p. 1911 - 1920 10 p.

    Research output: Contribution to journalArticle

  33. Multiple small doses of levodopa plus entacapone produce continuous dopaminergic stimulation and reduce dyskinesia induction in MPTP-treated drug-naive primates

    Smith, L. A., Jackson, M. J., Al-Barghouthy, G., Rose, S., Kuoppamaki, M., Olanow, W. & Jenner, P., Mar 2005, In : Movement Disorders. 20, 3, p. 306 - 314 9 p.

    Research output: Contribution to journalArticle

  34. Role of inducible nitric oxide synthase in N-methyl-D-aspartic acid-induced strio-nigral degeneration

    Iravani, M. M., Liu, L., Rose, S. & Jenner, P., 10 Dec 2004, In : Brain Research. 1029, 1, p. 103 - 113 11 p.

    Research output: Contribution to journalArticle

  35. Osteopontin (Eta-1) is present in the rat basal ganglia

    Iczkiewicz, J., Rose, S. & Jenner, P., 6 Dec 2004, In : Molecular Brain Research. 132, 1, p. 64 - 72 9 p.

    Research output: Contribution to journalArticle

  36. Alterations in expression of dopamine receptors and neuropeptides in the striatum of GTP cyclohydrolase-deficient mice

    Zeng, B. Y., Heales, S. J. R., Canevari, L., Rose, S. & Jenner, P., Dec 2004, In : Experimental Neurology. 190, 2, p. 515 - 524 10 p.

    Research output: Contribution to journalArticle

  37. SLV 308: Plasma levels of effective doses in MPTP-treated marmosets in comparison with plasma levels and D-2 receptor occupancy (PET) in humans

    De Vries, M. H., Hesselink, M. B., Winsemius, A. A., Jenner, P., Johnston, L. & Salvage, S., 2004, In : Clinical Pharmacology and Therapeutics. 75, 2, p. P70

    Research output: Contribution to journalArticle

  38. Differential expression of cytochrome P450 enzymes in cultured and intact foetal rat ventral mesencephalon

    Gilbert, E. A., Edwards, R. J., Boobis, A. R., Rose, S. & Jenner, P., Oct 2003, In : Journal of Neural Transmission. 110, 10, p. 1091 - 1101 11 p.

    Research output: Contribution to journalArticle

  39. Activities of extract and constituents of Banisteriopsis caapi relevant to parkinsonism

    Schwarz, M. J., Houghton, P. J., Rose, S., Jenner, P. & Lees, A. D., Jun 2003, In : Pharmacology Biochemistry and Behavior. 75, 3, p. 627 - 633 7 p.

    Research output: Contribution to journalArticle

  40. Inhibition of neuronal nitric oxide synthase increases dopamine efflux from rat striatum

    Silva, M. T., Rose, S., Hindmarsh, J. G. & Jenner, P., 1 Apr 2003, In : Journal of Neural Transmission. 110, 4, p. 353 - 362 10 p.

    Research output: Contribution to journalArticle

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