Projects per year
Search results
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Active
Importance of zinc in nitric oxide and NRF2-regulated redox signalling in human brain microvascular endothelial cells under physiological shear stress and oxygen levels
Mann, G. (Primary Investigator), Chapple, S. (Co-Investigator) & Morrell, A. (Co-Investigator)
1/04/2024 → 31/03/2027
Project: Research
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Nrf2 targeting to improve transgenerational islet function
Chapple, S. (Primary Investigator), Bowe, J. (Co-Investigator) & Malik, A. (Co-Investigator)
1/04/2024 → 31/03/2027
Project: Research
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Finished
SFRR-E: Rescuing islet oxidative stress through Nrf2 induction in adverse pregnancy
Chapple, S. (Primary Investigator)
SFRR-E Society for Free Radical Research Europe
1/05/2022 → 30/04/2023
Project: Research
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Sulforaphane improves maternal glucose handling in obese insulin-resistant pregnancy; consequences for uterine blood flow, placental function and offspring metabolism
Chapple, S. (Primary Investigator) & Nandi, M. (Co-Investigator)
1/03/2020 → 28/02/2023
Project: Research
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Identifying a therapeutic window for sulforaphane to improve glucose handling during pregnancy
Chapple, S. (Primary Investigator)
15/10/2019 → 14/10/2021
Project: Research
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Metallomic profiling and redox signalling in human coronary artery endothelial and smooth muscle cells in physiological normoxia and ischaemia/reperfusion injury
Mann, G. (Primary Investigator), Maret, W. (Co-Investigator), Chapple, S. (Co-Investigator) & Stewart, T. (Co-Investigator)
2/02/2019 → 28/09/2021
Project: Research
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Does Sulforaphane attenuate metabolic syndrome following obese pregnancy?
Chapple, S. (Primary Investigator)
1/09/2018 → 30/11/2019
Project: Research
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Activation of Nrf2 antioxidant defences by sulforaphane confers vascular protection in offspring exposed to a maternal obesogenic diet
Chapple, S. (Primary Investigator), Mann, G. (Co-Investigator) & Taylor, P. (Co-Investigator)
2/01/2018 → 1/01/2021
Project: Research
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Sulforaphane induced activation of Nrf2 signalling in a murine model of obesogenic gestational diabetes: potential therapy for reducing risk of cardiometabolic disease in mothers and offspring
Chapple, S. (Primary Investigator), Mann, G. (Co-Investigator) & Taylor, P. (Co-Investigator)
18/10/2016 → 17/10/2018
Project: Research
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Sulforaphane induced activation of Nrf2 signalling in a murine model of obesogenic
Chapple, S. (Primary Investigator), Mann, G. (Co-Investigator) & Taylor, P. (Co-Investigator)
1/08/2016 → 31/07/2019
Project: Research
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Regulation of eNOS/Hsp90/Akt interaction and nitric oxide synthesis in human fetal endothelial cells in pre-eclampsia.
Mann, G. (Primary Investigator), Chapple, S. (Co-Investigator) & Siow, R. (Co-Investigator)
1/02/2007 → 31/01/2010
Project: Research