Research output per year
Research output per year
Personal profile
Research interests
The main focus of Dr Thomas' laboratory is to investigate the ability of molecules to cross the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (choroid plexuses and arachnoid membrane) and reach the central nervous system (CNS) in health and disease. Dr Thomas and her group are especially interested in membrane transporters and the relationship between drug concentrations in the cerebrospinal fluid (CSF) and the brain tissue
Research interests (short)
Blood-brain barrier and blood-CSF barrier (choroid plexus): relationship to drug delivery.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Identification of transport systems involved in eflornithine delivery across the blood-brain barrier
Watson, C., Sekhar, G. & Thomas, S., 23 May 2023, (E-pub ahead of print) In: Frontiers in Drug Delivery. p. 1-14 14 p., 1113493.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease
Boyanova, S. T., Lloyd-Morris, E., Corpe, C., Rahman, K. M., Farag, D. B., Page, L. K., Wang, H., Fleckney, A. L., Gatt, A., Troakes, C., Vizcay-Barrena, G., Fleck, R., Reeves, S. J. & Thomas, S. A., 16 Aug 2023, In: PLoS ONE. 18, 10 OCTOBER, p. e0286278 e0286278.Research output: Contribution to journal › Article › peer-review
Open Access -
Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer’s disease. Interaction of amisulpride with GLUT1 at the blood-brain barrier.
Boyanova, S., Lloyd-Morris, E., Corpe, C., Rahman, M., Farag, D., Page, L., Wang, H., Fleckney, A., Gatt, A., Troakes, C., Vizcay-Barrena, G., Fleck, R., Reeves, S. & Thomas, S., 24 Oct 2023, In: PLoS One. 18, 10, p. 1-32 32 p., e0286278.Research output: Contribution to journal › Article › peer-review
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Question: Why do some of our organs come in pairs, such as kidneys, whereas we only have one heart, one liver etc? Why have two when one will do
Thomas, S., 3 May 2023, (Unpublished) In: New Scientist.Research output: Contribution to journal › Editorial
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Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug
Sanderson, L., Da Silva, M., Sekhar, G., Brown, R., Burrell-Saward, H., Fidanboylu, M., Liu, B., Dailey, L. A., Dreiss, C., Lorenz, C., Christie, M., Persaud, S., Yardley, V., Croft, S., Valero, M. & Thomas, S., 15 Apr 2021, In: PLoS Neglected Tropical Diseases. 15, 4, 31 p., e0009276.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)80 Downloads (Pure)
Projects
- 16 Finished
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Investigating how the novel hormone Kisspeptin modulates sexual and emotional brain processing in response to odour cues
18/12/2018 → 31/01/2021
Project: Research
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Assessing the role of ion-pair complexes during the transit of molecules from the skin to the brain
Jones, S., Ameer-Beg, S. & Thomas, S.
1/04/2015 → 31/03/2018
Project: Research
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Clinically-relevant intravenous delivery of recombinant human neutrophin 3 after stroke: pharmacokinetics, biodistribution, infarct volume and recovery in elderly mice
Moon, L., Begley, D., Cash, D., Thomas, S. & Williams, S.
1/01/2014 → 31/12/2016
Project: Research
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NANOHAT: Development of a safer and more effective sleeping sickness drug
Thomas, S., Christie, M., Dreiss, C., Lorenz, C. & Persaud, S.
1/01/2013 → 18/10/2015
Project: Research
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NANOHAT: development of a safer, more effective sleeping sickness drug
Dreiss, C., Thomas, S., Croft, S., Lorenz, C., Persaud, S. & Yardley, V.
1/10/2012 → 31/03/2015
Project: Research
Activities
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Journal of Pharmaceutical Science (Journal)
Sarah Thomas (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Life Sciences (Journal)
Sarah Thomas (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Cerebrospinal Fluid Research (Journal)
Sarah Thomas (Editorial board member)
2001 → …Activity: Publication peer-review and editorial work › Editorial activity
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CSF Research (Journal)
Sarah Thomas (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Journal of Controlled Drug Release (Journal)
Sarah Thomas (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review