Shahram Kordasti

2023

Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells

Couch, A., Solomon, S., Rafagnin Duarte, R. R., Marrocu, A., Sun, Y., Sichlinger, L., Matuleviciute, R., Dutan Polit, L., Hanger, B., Brown, A., Kordasti, S., Srivastava, D. & Vernon, A., 11 Feb 2023, In: Brain Behaviour and Immunity. https://doi.org/10.1016/j.bbi.2023.02.007, https://doi.org/10.1016/j.bbi.2023.02.007.

Research output: Contribution to journal › Article › peer-review

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Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells

Couch, A. C. M., Solomon, S., Duarte, R. R. R., Marrocu, A., Sun, Y., Sichlinger, L., Matuleviciute, R., Polit, L. D., Hanger, B., Brown, A., Kordasti, S., Srivastava, D. P. & Vernon, A. C., May 2023, In: Brain, Behavior, and Immunity. 110, p. 43-59 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

A pro-inflammatory environment in bone marrow of Treg transplanted patients matches with graft-versus-leukemia effect

Guardalupi, F., Sorrentino, C., Corradi, G., Giancola, R., Baldoni, S., Ulbar, F., Fabi, B., Andres ejarque, R., Timms, J., Restuccia, F., Santarone, S., Accorsi, P., Sportoletti, P., De falco, F., Rosati, E., Carotti, A., Falzetti, F., Velardi, A., Martelli, M. F., Kordasti, S., & 3 othersPierini, A., Ruggeri, L. & Di ianni, M., 1 Jul 2023, In: Leukemia. 37, 7, p. 1572-1575 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Differential inhibition of T-cell receptor and STAT5 signaling pathways determines the immunomodulatory effects of dasatinib in chronic phase chronic myeloid leukemia

Harrington, P., Dillon, R., Radia, D., Rousselot, P., Mclornan, D. P., Ong, M., Green, A., Verde, A., Hussain, F., Raj, K., Kordasti, S., Harrison, C. & De lavallade, H., Jun 2023, In: Haematologica. 108, 6, p. 1555-1566 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Distinct Clinical and Prognostic Features of Myelodysplastic Syndrome in Patients from the Middle East, North Africa, and Beyond: A Systemic Review

Al-Haidose, A., Yassin, M. A., Ahmed, M. N., Kunhipurayil, H. H., Al-Harbi, A. A., Aljaberi, M. A., Abbasi, S. A., Kordasti, S. & Abdallah, A. M., 12 Apr 2023, In: Journal of Clinical Medicine. 12, 8, 2832.

Research output: Contribution to journal › Review article › peer-review

Open Access

LYVE-1 ⁺ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

Anstee, J. E., Feehan, K. T., Opzoomer, J. W., Dean, I., Muller, H. P., Bahri, M., Cheung, T. S., Liakath-Ali, K., Liu, Z., Choy, D., Caron, J., Sosnowska, D., Beatson, R., Muliaditan, T., An, Z., Gillett, C. E., Lan, G., Zou, X., Watt, F. M., Ng, T., & 5 othersBurchell, J. M., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., 11 Sept 2023, In: Developmental Cell. 58, 17, p. 1548-1561.e10

Research output: Contribution to journal › Article › peer-review

Open Access

Multiparameter flow cytometry in the evaluation of myelodysplasia: Analytical issues: Recommendations from the European LeukemiaNet/International Myelodysplastic Syndrome Flow Cytometry Working Group

Porwit, A., Béné, M. C., Duetz, C., Matarraz, S., Oelschlaegel, U., Westers, T. M., Wagner-Ballon, O., Kordasti, S., Valent, P., Preijers, F., Alhan, C., Bellos, F., Bettelheim, P., Burbury, K., Chapuis, N., Cremers, E., Della Porta, M. G., Dunlop, A., Eidenschink-Brodersen, L., Font, P., & 15 othersFontenay, M., Hobo, W., Ireland, R., Johansson, U., Loken, M. R., Ogata, K., Orfao, A., Psarra, K., Saft, L., Subira, D., te Marvelde, J., Wells, D. A., van der Velden, V. H. J., Kern, W. & van de Loosdrecht, A. A., Jan 2023, In: Cytometry Part B - Clinical Cytometry. 104, 1, p. 27-50 24 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Citation (Scopus)

Real world experience with ropeginterferon alpha-2b (Besremi) in essential thrombocythaemia and polycythaemia vera following exposure to pegylated interferon alfa-2a (Pegasys)

Okikiolu, J., Woodley, C., Cadman-Davies, L., O'Sullivan, J., Radia, D., Garcia, N. C., Harrington, P., Kordasti, S., Asirvatham, S., Sriskandarajah, P., Saunders, J., Saha, C., Sanchez, I., deLavallade, H., McLornan, D. P. & Harrison, C. N., Jan 2023, In: Leukemia Research Reports. 19, 100360.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Real-World Validation of Molecular International Prognostic Scoring System for Myelodysplastic Syndromes

Sauta, E., Robin, M., Bersanelli, M., Travaglino, E., Meggendorfer, M., Zhao, L-P., Caballero berrocal, J. C., Sala, C., Maggioni, G., Bernardi, M., Di grazia, C., Vago, L., Rivoli, G., Borin, L., D'amico, S., Tentori, C. A., Ubezio, M., Campagna, A., Russo, A., Mannina, D., & 28 othersLanino, L., Chiusolo, P., Giaccone, L., Voso, M. T., Riva, M., Oliva, E. N., Zampini, M., Riva, E., Nibourel, O., Bicchieri, M., Bolli, N., Rambaldi, A., Passamonti, F., Savevski, V., Santoro, A., Germing, U., Kordasti, S., Santini, V., Diez-Campelo, M., Sanz, G., Sole, F., Kern, W., Platzbecker, U., Ades, L., Fenaux, P., Haferlach, T., Castellani, G. & Della porta, M. G., 20 May 2023, In: Journal of Clinical Oncology. 41, 15, p. 2827-2842 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (Scopus)

Synthetic Data Generation by Artificial Intelligence to Accelerate Research and Precision Medicine in Hematology

D'amico, S., Dall’olio, D., Sala, C., Dall’olio, L., Sauta, E., Zampini, M., Asti, G., Lanino, L., Maggioni, G., Campagna, A., Ubezio, M., Russo, A., Bicchieri, M. E., Riva, E., Tentori, C. A., Travaglino, E., Morandini, P., Savevski, V., Santoro, A., Prada-Luengo, I., & 9 othersKrogh, A., Santini, V., Kordasti, S., Platzbecker, U., Diez-Campelo, M., Fenaux, P., Haferlach, T., Castellani, G. & Della porta, M. G., 1 Jun 2023, In: JCO Clinical Cancer Informatics. 7, 7, p. e2300021

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia

Mian, S. A., Philippe, C., Maniati, E., Protopapa, P., Bergot, T., Piganeau, M., Nemkov, T., Di Bella, D., Morales, V., Finch, A. J., D'Alessandro, A., Bianchi, K., Wang, J., Gallipoli, P., Kordasti, S., Kubasch, A. S., Cross, M., Platzbecker, U., Wiseman, D. H., Bonnet, D., & 3 othersBernard, D. G., Gribben, J. G. & Rouault-Pierre, K., 1 Mar 2023, In: Science translational medicine. 15, 685, eabn5135.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

2022

Chronic myeloid leukaemia patients at diagnosis and resistant to tyrosine kinase inhibitor therapy display exhausted T-cell phenotype

Harrington, P., Dillon, R., Radia, D., McLornan, D., Woodley, C., Asirvatham, S., Raj, K., Curto-Garcia, N., Saunders, J., Kordasti, S., Harrison, C. & de Lavallade, H., Sept 2022, In: British Journal of Haematology. 198, 6, p. 1011-1015 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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4 Citations (Scopus)

107 Downloads (Pure)

Hostile Takeover: Tregs expand in IFN-γ-rich AML microenvironment

Ferrell, P. B. & Kordasti, S., 15 Jul 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 14, p. 2986-2988 3 p.

Research output: Contribution to journal › Article › peer-review

Predicting Progression Free Survival after Systemic Therapy in Advanced Head and Neck Cancer: Bayesian regression and Model development

Barber, P. R., Mustapha, R., Flores-Borja, F., Alfano, G., Ng, K., Weitsman, G., Dolcetti, L., Suwaidan, A. A., Wong, F., Vicencio Bustamante, J., Galazi, M., Opzoomer, J., Arnold, J., Thavaraj, S., Kordasti, S., Doyle, J., Greenberg, J., Dillon, M., Harrington, K. J., Forster, M., & 2 othersCoolen, A. CC. & Ng, T., 23 Dec 2022, (E-pub ahead of print) In: eLife. In press

Research output: Contribution to journal › Article › peer-review

Open Access

1 Downloads (Pure)

Regulatory T cell niche in the bone marrow, a new player in Haematopoietic stem cell transplantation

Ashman, J., Mutsonziwa, N., Romano, M., Kordasti, S., Lombardi, G. & Shangaris, P., 31 Oct 2022, In: Blood Reviews. p. 101030 101030.

Research output: Contribution to journal › Article › peer-review

Open Access

Third-dose SARS-CoV-2 mRNA vaccine increases Omicron variant neutralisation in patients with chronic myeloid disorders

Harrington, P., Kurshan, A., Delord, M., Lechmere, T., Sheikh, A., Saunders, J., Saha, C., Dillon, R., Woodley, C., Asirvatham, S., Curto-Garcia, N., O'Sullivan, J., Kordasti, S., Radia, D. H., McLornan, D. P., Malim, M. H., Harrison, C. N., Doores, K. J. & de Lavallade, H., 9 Sept 2022, (E-pub ahead of print) In: Blood Advances. 7, 10

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling

Goldberg, R., Clough, J. N., Roberts, L. B., Sanchez, J., Kordasti, S., Petrov, N., Hertweck, A., Lorenc, A., Jackson, I., Tasker, S., Appios, A., Omer, O., Parkes, M., Prescott, N., Jenner, R. G., Irving, P. M. & Lord, G. M., 18 Dec 2021, In: Journal of Crohn's & colitis. 15, 12, p. 2054-2065 12 p., jjab103.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes

Kordasti, S., 10 Apr 2021, In: JCO. 39, 11, p. 1223-1233 11 p., DOI: 10.1200/JCO.20.01659 Journal of Clinical Oncology.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Citations (Scopus)

Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet International MDS-Flow Cytometry Working Group

van de Loosdrecht, A. A., Kern, W., Porwit, A., Valent, P., Kordasti, S., Cremers, E., Alhan, C., Duetz, C., Dunlop, A., Hobo, W., Preijers, F., Wagner-Ballon, O., Chapuis, N., Fontenay, M., Bettelheim, P., Eidenschink-Brodersen, L., Font, P., Johansson, U., Loken, M. R., te Marvelde, J. G., & 15 othersMatarraz, S., Ogata, K., Oelschlaegel, U., Orfao, A., Psarra, K., Subirá, D., Wells, D. A., Béné, M. C., Della Porta, M. G., Burbury, K., Bellos, F., van der Velden, V. H. J., Westers, T. M., Saft, L. & Ireland, R., 2021, (Accepted/In press) In: Cytometry Part B - Clinical Cytometry.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Clinicopathological characterisation of myeloproliferative neoplasm-unclassifiable (MPN-U): a retrospective analysis from a large UK tertiary referral centre

Deschamps, P., Moonim, M., Radia, D., Curto-Garcia, N., Woodley, C., Bassiony, S., O'Sullivan, J., Harrington, P., Raj, K., Francis, Y., Kordasti, S., Ali, S., Harrison, C. N. & McLornan, D. P., May 2021, In: British Journal of Haematology. 193, 4, p. 792-797 6 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

COVID-19 Risk Factors for Cancer Patients: A First Report with Comparator Data from COVID-19 Negative Cancer Patients

Russell, B., Moss, C. L., Palmer, K., Sylva, R., D'Souza, A., Wylie, H., Haire, A., Cahill, F., Steel, R., Hoyes, A., Wilson, I., Macneil, A., Shifa, B., Monroy-Iglesias, M. J., Papa, S., Irshad, S., Ross, P., Spicer, J., Kordasti, S., Crawley, D., & 12 othersZaki, K., Sita-Lumsden, A., Josephs, D., Enting, D., Swampillai, A., Sawyer, E., Fields, P., Wrench, D., Rigg, A., Sullivan, R., Van Hemelrijck, M. & Dolly, S., 19 May 2021, In: Cancers. 13, 10, 2479.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Citations (Scopus)

Erratum: Repeated vaccination against SARS-CoV-2 elicits robust polyfunctional T cell response in allogeneic stem cell transplantation recipients (Cancer Cell (2021) 39(11) (1448–1449), (S1535610821005444), (10.1016/j.ccell.2021.10.002))

Harrington, P., Doores, K. J., Saha, C., Saunders, J., Child, F., Dillon, R., Saglam, S., Raj, K., McLornan, D., Avenoso, D., Kordasti, S., O'Reilly, A., Espehana, A., Lechmere, T., Khan, H., Malim, M. H., Harrison, C., Mehra, V. & de Lavallade, H., 13 Dec 2021, In: CANCER CELL. 39, 12, p. 1654 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

3 Citations (Scopus)

Flow cytometric analysis of myelodysplasia: Pre-analytical and technical issues—Recommendations from the European LeukemiaNet

van der Velden, V. H. J., Preijers, F., Johansson, U., Westers, T. M., Dunlop, A., Porwit, A., Béné, M. C., Valent, P., te Marvelde, J., Wagner-Ballon, O., Oelschlaegel, U., Saft, L., Kordasti, S., Ireland, R., Cremers, E., Alhan, C., Duetz, C., Hobo, W., Chapuis, N., Fontenay, M., & 16 othersBettelheim, P., Eidenshink-Brodersen, L., Font, P., Loken, M. R., Matarraz, S., Ogata, K., Orfao, A., Psarra, K., Subirá, D., Wells, D. A., Della Porta, M. G., Burbury, K., Bellos, F., Weiß, E., Kern, W. & van de Loosdrecht, A., 2021, (Accepted/In press) In: Cytometry Part B - Clinical Cytometry.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

ImmunoCluster provides a computational framework for the non-specialist to profile high- dimensional cytometry data

Opzoomer, J. W., Timms, J. A., Blighe, K., Mourikis, T. P., Chapuis, N., Bekoe, R., Kareemaghay, S., Nocerino, P., Apollonio, B., Ramsay, A. G., Tavassoli, M., Harrison, C., Ciccarelli, F. D., Parker, P., Fontenay, M., Barber, P. R., Arnold, J. N. & Kordasti, S., Apr 2021, In: eLife. 10, e62915.

Research output: Contribution to journal › Article › peer-review

Open Access

File

4 Citations (Scopus)

171 Downloads (Pure)

Large Scale Internet-based Survey of Patients With a Myeloproliferative Neoplasm: Opinions and Experiences Regarding SARS-CoV-2 (COVID-19) Vaccination Strategies in 2021

Saunders, J., Curto-Garcia, N., Sriskandarajah, P., O'Sullivan, J., Woodley, C., Asirvatham, S., Campbell-Drew, M., Mathias, J., Ellis, T., Baker, N., Radia, D. H., Ali, S., Kordasti, S., Harrington, P., de Lavallade, H., McLornan, D. P. & Harrison, C. N., Jul 2021

Research output: Other contribution

Open Access

1 Citation (Scopus)

Low-dose Splenic Irradiation in Conjunction With Ruxolitinib to Provide Symptomatic Relief in Heavily Treated, Advanced Stage Myelofibrosis: A Case Series From a UK Tertiary Referral Center

Khan, A., Woodley, C., Radia, D., Mikhaeel, G. N., Brady, J., Garcia, N. C., Harrington, P., O'Sullivan, J., Kordasti, S., Francis, Y., Asirvatham, S., Ali, S., Sriskandarajah, P., Saunders, J., de Lavallade, H., McLornan, D. P. & Harrison, C. N., Jul 2021, In: HemaSphere. 5, 7, e611.

Research output: Contribution to journal › Article › peer-review

Open Access

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Lyve-1 expressing macrophages direct the expansion of pericytes within the perivascular niche to support angiogenesis in cancer.

Opzoomer, J. W., Anstee, J. E., Dean, I., Hill, E. J., Bouybayoune, I., Caron, J., Muliaditan, T., Gordon, P., Nuamah, R., Pinder, S. E., Ng, T., Dazzi, F., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., Jul 2021, In: Cancer Research. 81, 13

Research output: Contribution to journal › Meeting Abstract › peer-review

Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression

Opzoomer, J. W., Anstee, J. E., Dean, I., Hill, E. J., Bouybayoune, I., Caron, J., Muliaditan, T., Gordon, P., Sosnowska, D., Nuamah, R., Pinder, S. E., Ng, T., Dazzi, F., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., 5 Nov 2021, In: Science Advances. 7, 45, p. eabg9518 eabg9518.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Citations (Scopus)

Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression

Opzoomer, J. W., Anstee, J. E., Dean, I., Hill, E. J., Bouybayoune, I., Caron, J., Muliaditan, T., Gordon, P., Sosnowska, D., Nuamah, R., Pinder, S. E., Ng, T., Dazzi, F., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., 3 Nov 2021, In: Science Advances.

Research output: Contribution to journal › Article › peer-review

Open Access

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100 Downloads (Pure)

Patients with triple-negative, JAK2V617F- and CALR-mutated essential thrombocythemia share a unique gene expression signature

Alimam, S., Villiers, W., Dillon, R., Simpson, M., Runglall, M., Smith, A., Chatzikyriakou, P., Lavender, P., Kanda, A., Mills, K., Bellosillo Paricio, B., Kaufman-Cook, J., Ord, S., Kordasti, S., Radia, D., Woodley, C., Francis, Y., Mufti, G., McLornan, D. P. & Harrison, C. N., 23 Feb 2021, In: Blood Advances. 5, 4, p. 1059-1068 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

Reduced frequencies and functional impairment of dendritic cell subsets and non-classical monocytes in myelodysplastic syndromes

Van Leeuwen-Kerkhoff, N., Westers, T. M., Poddighe, P. J., Povoleri, G. A. M., Timms, J. A., Kordasti, S., De Gruijl, T. D. & Van de Loosdrecht, A. A., 11 Feb 2021, (E-pub ahead of print) In: Haematologica.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Repeated vaccination against SARS-CoV-2 elicits robust polyfunctional T cell response in allogeneic stem cell transplantation recipients

Harrington, P., Doores, K. J., Saha, C., Saunders, J., Child, F., Dillon, R., Saglam, S., Raj, K., McLornan, D., Avenoso, D., Kordasti, S., O'Reilly, A., Espehana, A., Lechmere, T., Khan, H., Malim, M. H., Harrison, C., Mehra, V. & de Lavallade, H., 8 Nov 2021, In: CANCER CELL. 39, 11, p. 1448-1449 2 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

19 Citations (Scopus)

Risk of COVID-19 death in cancer patients: an analysis from Guy's Cancer Centre and King's College Hospital in London

Guy’s Cancer Real World Evidence, 28 Sept 2021, In: British journal of cancer. 125, 7, p. 939-947 9 p.

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

Yan, B., Freiwald, T., Chauss, D., Wang, L., West, E., Mirabelli, C., Zhang, C. J., Nichols, E-M., Malik, N., Gregory, R., Bantscheff, M., Ghidelli-Disse, S., Kolev, M., Frum, T., Spence, J. R., Sexton, J. Z., Alysandratos, K. D., Kotton, D. N., Pittaluga, S., Bibby, J., & 10 othersNiyonzima, N., Olson, M. R., Kordasti, S., Portilla, D., Wobus, C. E., Laurence, A., Lionakis, M. S., Kemper, C., Afzali, B. & Kazemian, M., 7 Apr 2021, In: Science Immunology. 6, 58, eabg0833.

Research output: Contribution to journal › Article › peer-review

89 Citations (Scopus)

Single dose of BNT162b2 mRNA vaccine against SARS-CoV-2 induces high frequency of neutralising antibody and polyfunctional T-cell responses in patients with myeloproliferative neoplasms

Harrington, P., de Lavallade, H., Doores, K. J., O'Reilly, A., Seow, J., Graham, C., Lechmere, T., Radia, D., Dillon, R., Shanmugharaj, Y., Espehana, A., Woodley, C., Saunders, J., Curto-Garcia, N., O'Sullivan, J., Raj, K., Kordasti, S., Malim, M. H., Harrison, C. N. & McLornan, D. P., Dec 2021, In: Leukemia. 35, 12, p. 3573-3577 5 p.

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Single dose of BNT162b2 mRNA vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induces neutralising antibody and polyfunctional T-cell responses in patients with chronic myeloid leukaemia

Harrington, P., Doores, K. J., Radia, D., O'Reilly, A., Lam, H. P. J., Seow, J., Graham, C., Lechmere, T., McLornan, D., Dillon, R., Shanmugharaj, Y., Espehana, A., Woodley, C., Saunders, J., Curto-Garcia, N., O'Sullivan, J., Raj, K., Kordasti, S., Malim, M. H., Harrison, C., & 1 othersde Lavallade, H., Sept 2021, In: British Journal of Haematology. 194, 6, p. 999-1006 8 p.

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

Katy Rezvani, 4 Feb 2021, In: Blood. 137, 5, p. 624–636 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

98 Citations (Scopus)

123 Downloads (Pure)

2020

Anti-TNF treatment negatively regulates human CD4+ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype

Povoleri, G. A. M., Lalnunhlimi, S., Steel, K. J. A., Agrawal, S., O'Byrne, A., Ridley, M., Kordasti, S., Frederiksen, K. S., Roberts, C. A. & Taams, L. S., Mar 2020, In: European Journal of Immunology. 50, 3, p. 445-458 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

9 Citations (Scopus)

125 Downloads (Pure)

Deep phenotyping detects a pathological CD4+ T-cell complosome signature in systemic sclerosis

Arbore, G., Ong, V. H., Costantini, B., Denton, C. P., Abraham, D., Placais, L., Blighe, K., Mitchell, L., Ellis, R., Heck, S., Nocerino, P., Woodruff, T. M., Kordasti, S., Kemper, C. & Hourcade, D. E., 1 Sept 2020, In: Cellular and Molecular Immunology. 17, 9, p. 1010-1013 4 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

File

7 Citations (Scopus)

78 Downloads (Pure)

Factors Affecting COVID-19 Outcomes in Cancer Patients: A First Report From Guy's Cancer Center in London

Russell, B., Moss, C., Papa, S., Irshad, S., Ross, P., Spicer, J., Kordasti, S., Crawley, D., Wylie, H., Cahill, F., Haire, A., Zaki, K., Rahman, F., Sita-Lumsden, A., Josephs, D., Enting, D., Lei, M., Ghosh, S., Harrison, C., Swampillai, A., & 14 othersSawyer, E., D'Souza, A., Gomberg, S., Fields, P., Wrench, D., Raj, K., Gleeson, M., Bailey, K., Dillon, R., Streetly, M., Rigg, A., Sullivan, R., Dolly, S. & Van Hemelrijck, M., 22 Jul 2020, In: Frontiers in oncology. 26, 18, 1279.

Research output: Contribution to journal › Article › peer-review

Open Access

File

38 Citations (Scopus)

20 Downloads (Pure)

Factors affecting COVID-19 outcomes in cancer patients from Guy's Cancer Center and King's College Hospital.

Palmer, K., Sylva, R., Russell, B., Moss, C., Shah, V., Ko, T. K., George, G., Kordasti, S., Crawley, D., Wylie, H., Cahill, F., Haire, A., Zaki, K., Sita-Lumsden, A., Josephs, D., Enting, D., Swampillai, A., Sawyer, E., Lei, M., D'Souza, A., & 8 othersGomberg, S., Fields, P., Wrench, D., Sullivan, R., Rigg, A., Kulasekararaj, A., Van Hemelrijck, M. & Dolly, S., Mar 2020, In: Clinical Cancer Research. 27, 6

Research output: Contribution to journal › Meeting Abstract › peer-review

Immunocluster: A Computational Tool to Explore the Immune Profile and Cellular Heterogeneity of Hematological Diseases Using Liquid and Imaging Mass, and Flow Cytometry Data

Timms, J. A., Opzoomer, J. W., Blighe, K., Apollonio, B., Mourikis, T., Chapuis, N., Bekoe, R., Ramsay, A. G., McLornan, D. P., Harrison, C., Barber, P. R., Parker, P., Fontenay, M., Arnold, J. N. & Kordasti, S., 5 Nov 2020, In: Blood. 136

Research output: Contribution to journal › Meeting Abstract › peer-review

Immunological effects of ponatinib therapy in patients with chronic myeloid leukaemia

Harrington, P., Radia, D., Lim, M., Dillon, R., Kordasti, S., Rezvani, K., Harrison, C. & de Lavallade, H., Apr 2020, In: British Journal of Haematology. 189, p. 72-73

Research output: Contribution to journal › Meeting Abstract › peer-review

9 Citations (Scopus)

Inhibition of Immune Cell Subsets Is Differentially Affected By Dasatinib Dosage in Patients with Chronic Phase CML

Harrington, P., Dillon, R., Radia, D. H., McLornan, D. P., Rousselot, P., Rezvani, K., Kordasti, S., Harrison, C. & de Lavallade, H., 5 Nov 2020, In: Blood. 136

Research output: Contribution to journal › Meeting Abstract › peer-review

Integrating the "Immunome" in the Stratification of Myelodysplastic Syndromes and Future Clinical Trial Design: Systems immunology; a way forward in MDS

Winter, S., Shoaie, S., Kordasti, S. & Platzbecker, U., 20 May 2020, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 38, 15, p. 1723-1735 13 p., jco.19.01823.

Research output: Contribution to journal › Article › peer-review

Open Access

File

43 Citations (Scopus)

185 Downloads (Pure)

Natural born survivors: the inglorious TP53

Platzbecker, U. & Kordasti, S., 10 Dec 2020, In: Blood. 136, 24, p. 2727-2728 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

2 Citations (Scopus)

Pitfalls in the characterization of circulating and tissue-resident human γδ T cells

Beucke, N., Wesch, D., Oberg, H-H., Peters, C., Bochem, J., Weide, B., Garbe, C., Pawelec, G., Sebens, S., Röcken, C., Hashimoto, H., Löffler, M. W., Nocerino, P., Kordasti, S., Kabelitz, D., Schilbach, K. & Wistuba-Hamprecht, K., 1 Jun 2020, In: Journal of Leukocyte Biology. 107, 6, p. 1097-1105 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

313 Downloads (Pure)

Refining the erythrocytosis diagnostic pathway: an audit of current practice compared to British Society for Haematology guidelines

Williams, R., Curto-Garcia, N., O'Sullivan, J., Radia, D., McLornan, D., Kordasti, S., Francis, Y., Woodley, C. & Harrison, C., Apr 2020, In: British Journal of Haematology. 189, p. 74-75

Research output: Contribution to journal › Meeting Abstract › peer-review

SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyper-activation

Yan, B., Freiwald, T., Chauss, D., Wang, L., West, E., Bibby, J., Olson, M., Kordasti, S., Portilla, D., Laurence, A., Lionakis, M. S., Kemper, C., Afzali, B. & Kazemian, M., 9 Jun 2020, In: Research Findings.

Research output: Contribution to journal › Article

The impact of COVID-19 in the cancer population stratified by age: A real-world data study from Guy's Cancer Center.

Sylva, R., Russell, B., Moss, C., George, G., Palmer, K., Shah, V., Ko, T. K., Kalsi, T., Harari, D., De Michele, L., Kordasti, S., Crawley, D., Wylie, H., Cahill, F., Haire, A., D'Souza, A., Gomberg, S., Kulasekararaj, A., Van Hemelrijck, M. & Dolly, S., Mar 2020, In: Clinical Cancer Research. 27, 6

Research output: Contribution to journal › Meeting Abstract › peer-review

Shahram Kordasti

Research output

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