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Personal profile

Biographical details

After gaining my first degree in Physics from the University of Cambridge in 2003 I studied for a PhD in MRI image reconstruction at Imperial College London, which was awarded in 2008. I remained as a post doctoral researcher at Imperial College until 2012, taking a major role in working with a prototype Parallel Transmission MRI scanner: the first of its type in a hospital setting anywhere in the world. I joined King’s College as a lecturer in April 2012 and became an EPSRC Fellow in 2013. I won the ISMRM Young Investigator Award in 2012 for my work on parallel transmission. 

Research interests

My research focuses primarily on parallel transmission MRI - this is a next generation technology allowing flexible and dynamic control of radiofrequency (RF) magnetic fields.  This innovation has opened the door to previously unachievable methods for manipulating MRI contrast. Since being involved with the installation and early characterisation of a prototype system at Hammersmith Hospital, I am now focused on developing techniques for exploiting the resulting new degrees of freedom.  Initial applications included novel methods for controlling frequency selection properties of RF pulses and improving contrast of structural brain scans. Recent work has included development of methodology for controlling entire sequences of pulses, allowing for large improvements in achievable image quality. A related research theme is that of safety related to RF fields in MRI, which is particularly important when using novel RF systems. Recent work in this area has led to the proposal of safe and efficient scanning methods for cardiac MRI.  I have received funding from the EPSRC as an Early Career Fellow and from the MRC DPFS scheme to build new prototype technology. In the past I have worked on ultra-high field (7T) MRI research with collaborators at University Medical Centre Utrecht. We have now installed a 7T Siemens Terra MR system at St.Thomas' (funded in part by the Wellcome Trust) with the aim of bringing ultrahigh field MRI to a wide community of medical researchers across London. 

My secondary research focus is the development of new MR imaging techniques for foetal and neonatal subjects (and evaluation of safety in these patient groups), working closely with the department of Perinatal Imaging and Health. Recent work on this includes development of multi-band RF pulse methods that are increasingly important for rapid MRI in this and other population groups, and work on quantitative MR sequences, particularly those that interact with semisolid protons (i.e. 'magnetisation transfer') in the brain.

For further information see also my profile on Research Gate and for open source code (mainly Matlab) see mriphysics.github.io

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Science, Data Driven Reconstruction Methods for Dynamic Undersampled MRI, Imperial College London

Award Date: 1 Jan 2008

Master of Research, Imperial College London

Award Date: 1 Jan 2004

Master in Science, University of Cambridge

Award Date: 1 Jan 2003

Keywords

  • QC Physics

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