Simon Keller

2022

Event-based modeling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data

for the ENIGMA-Epilepsy Working Group, Lopez, S. M., Aksman, L. M., Oxtoby, N. P., Vos, S. B., Rao, J., Kaestner, E., Alhusaini, S., Alvim, M., Bender, B., Bernasconi, A., Bernasconi, N., Bernhardt, B., Bonilha, L., Caciagli, L., Caldairou, B., Caligiuri, M. E., Calvet, A., Cendes, F., Concha, L., & 31 othersConde-Blanco, E., Davoodi-Bojd, E., de Bézenac, C., Delanty, N., Desmond, P. M., Devinsky, O., Domin, M., Duncan, J. S., Focke, N. K., Foley, S., Fortunato, F., Galovic, M., Gambardella, A., Gleichgerrcht, E., Guerrini, R., Hamandi, K., Ives-Deliperi, V., Jackson, G. D., Jahanshad, N., Keller, S. S., Kochunov, P., Kotikalapudi, R., Kreilkamp, B. A. K., Labate, A., Larivière, S., Lenge, M., Lui, E., Malpas, C., Martin, P., Mascalchi, M. & Richardson, M., 10 Aug 2022, In: Epilepsia. 63, 8, p. 2081-2095 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression

Larivière, S., Royer, J., Rodríguez-Cruces, R., Paquola, C., Caligiuri, M. E., Gambardella, A., Concha, L., Keller, S. S., Cendes, F., Yasuda, C. L., Bonilha, L., Gleichgerrcht, E., Focke, N. K., Domin, M., von Podewills, F., Langner, S., Rummel, C., Wiest, R., Martin, P., Kotikalapudi, R., & 54 othersO’Brien, T. J., Sinclair, B., Vivash, L., Desmond, P. M., Lui, E., Vaudano, A. E., Meletti, S., Tondelli, M., Alhusaini, S., Doherty, C. P., Cavalleri, G. L., Delanty, N., Kälviäinen, R., Jackson, G. D., Kowalczyk, M., Mascalchi, M., Semmelroch, M., Thomas, R. H., Soltanian-Zadeh, H., Davoodi-Bojd, E., Zhang, J., Winston, G. P., Griffin, A., Singh, A., Tiwari, V. K., Kreilkamp, B. A. K., Lenge, M., Guerrini, R., Hamandi, K., Foley, S., Rüber, T., Weber, B., Depondt, C., Absil, J., Carr, S. J. A., Abela, E., Richardson, M. P., Devinsky, O., Severino, M., Striano, P., Tortora, D., Kaestner, E., Hatton, S. N., Vos, S. B., Caciagli, L., Duncan, J. S., Whelan, C. D., Thompson, P. M., Sisodiya, S. M., Bernasconi, A., Labate, A., McDonald, C. R., Bernasconi, N. & Bernhardt, B. C., Dec 2022, In: Nature Communications. 13, 1, 4320.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Citations (Scopus)

Topographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy

Park, B. Y., Larivière, S., Rodríguez-Cruces, R., Royer, J., Tavakol, S., Wang, Y., Caciagli, L., Caligiuri, M. E., Gambardella, A., Concha, L., Keller, S. S., Cendes, F., Alvim, M. K. M., Yasuda, C., Bonilha, L., Gleichgerrcht, E., Focke, N. K., Kreilkamp, B. A. K., Domin, M., Von Podewils, F., & 67 othersLangner, S., Rummel, C., Rebsamen, M., Wiest, R., Martin, P., Kotikalapudi, R., Bender, B., O'Brien, T. J., Law, M., Sinclair, B., Vivash, L., Kwan, P., Desmond, P. M., Malpas, C. B., Lui, E., Alhusaini, S., Doherty, C. P., Cavalleri, G. L., Delanty, N., Kälviäinen, R., Jackson, G. D., Kowalczyk, M., Mascalchi, M., Semmelroch, M., Thomas, R. H., Soltanian-Zadeh, H., Davoodi-Bojd, E., Zhang, J., Lenge, M., Guerrini, R., Bartolini, E., Hamandi, K., Foley, S., Weber, B., Depondt, C., Absil, J., Carr, S. J. A., Abela, E., Richardson, M. P., Devinsky, O., Severino, M., Striano, P., Parodi, C., Tortora, D., Hatton, S. N., Vos, S. B., Duncan, J. S., Galovic, M., Whelan, C. D., Bargalló, N., Pariente, J., Conde-Blanco, E., Vaudano, A. E., Tondelli, M., Meletti, S., Kong, X. Z., Francks, C., Fisher, S. E., Caldairou, B., Ryten, M., Labate, A., Sisodiya, S. M., Thompson, P. M., Mcdonald, C. R., Bernasconi, A., Bernasconi, N. & Bernhardt, B. C., 1 Apr 2022, In: Brain. 145, 4, p. 1285-1298 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Citations (Scopus)

2021

Artificial intelligence for classification of temporal lobe epilepsy with ROI-level MRI data: A worldwide ENIGMA-Epilepsy study

ENIGMA-Epilepsy Working Group, Jan 2021, In: NeuroImage: Clinical. 31, 102765.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Citations (Scopus)

A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies

ENIGMA-Epilepsy Working Group & EpiPGX Consortium, 5 Sept 2021, (E-pub ahead of print) In: Neuropathology and Applied Neurobiology. 48, 1

Research output: Contribution to journal › Article › peer-review

Open Access

14 Citations (Scopus)

Functional network topology in drug resistant and well-controlled idiopathic generalized epilepsy: a resting state functional MRI study

Pegg, E. J., Mckavanagh, A., Bracewell, R. M., Chen, Y., Das, K., Denby, C., Kreilkamp, B. A. K., Laiou, P., Marson, A., Mohanraj, R., Taylor, J. R. & Keller, S. S., 2021, In: Brain Communications. 3, 3, fcab196.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Citations (Scopus)

2020

Network-based atrophy modeling in the common epilepsies: A worldwide ENIGMA study

ENIGMA, 18 Nov 2020, In: Science Advances. 6, 47, eabc6457.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Citations (Scopus)

White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA-Epilepsy study

Hatton, S. N., Huynh, K. H., Bonilha, L., Abela, E., Alhusaini, S., Altmann, A., Alvim, M. K. M., Balachandra, A. R., Bartolini, E., Bender, B., Bernasconi, N., Bernasconi, A., Bernhardt, B., Bargallo, N., Caldairou, B., Caligiuri, M. E., Carr, S. J. A., Cavalleri, G. L., Cendes, F., Concha, L., & 56 othersDavoodi-Bojd, E., Desmond, P. M., Devinsky, O., Doherty, C. P., Domin, M., Duncan, J. S., Focke, N. K., Foley, S. F., Gambardella, A., Gleichgerrcht, E., Guerrini, R., Hamandi, K., Ishikawa, A., Keller, S. S., Kochunov, P. V., Kotikalapudi, R., Kreilkamp, B. A. K., Kwan, P., Labate, A., Langner, S., Lenge, M., Liu, M., Lui, E., Martin, P., Mascalchi, M., Moreira, J. C. V., Morita-Sherman, M. E., O'Brien, T. J., Pardoe, H. R., Pariente, J. C., Ribeiro, L. F., Richardson, M. P., Rocha, C. S., Rodríguez-Cruces, R., Rosenow, F., Severino, M., Sinclair, B., Soltanian-Zadeh, H., Striano, P., Taylor, P. N., Thomas, R. H., Tortora, D., Velakoulis, D., Vezzani, A., Vivash, L., von Podewils, F., Vos, S. B., Weber, B., Winston, G. P., Yasuda, C. L., Zhu, A. H., Thompson, P. M., Whelan, C. D., Jahanshad, N., Sisodiya, S. M. & McDonald, C. R., 1 Aug 2020, In: Brain : a journal of neurology. 143, 8, p. 2454-2473 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Citations (Scopus)

2019

Investigating imaging network markers of cognitive dysfunction and pharmacoresistance in newly diagnosed epilepsy: a protocol for an observational cohort study in the UK

de Bézenac, C., Garcia-Finana, M., Baker, G., Moore, P., Leek, N., Mohanraj, R., Bonilha, L., Richardson, M., Marson, A. G. & Keller, S., 16 Oct 2019, In: BMJ Open. 9, 10, p. e034347 e034347.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

2018

Hippocampal subfield segmentation in temporal lobe epilepsy: Relation to outcomes

Kreilkamp, B. A. K., Weber, B., Elkommos, S. B., Richardson, M. P. & Keller, S. S., 23 Mar 2018, (E-pub ahead of print) In: Acta Neurologica Scandinavica.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Citations (Scopus)

Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study

Whelan, C. D., Altmann, A., Botía, J. A., Jahanshad, N., Hibar, D. P., Absil, J., Alhusaini, S., Alvim, M. K. M., Auvinen, P., Bartolini, E., Bergo, F. P. G., Bernardes, T., Blackmon, K., Braga, B., Caligiuri, M. E., Calvo, A., Carr, S. J., Chen, J., Chen, S., Cherubini, A., & 30 othersDavid, P., Domin, M., Foley, S., França, W., Haaker, G., Isaev, D., Keller, S. S., Kotikalapudi, R., Kowalczyk, M. A., Kuzniecky, R., Langner, S., Lenge, M., Leyden, K. M., Liu, M., Loi, R. Q., Martin, P., Mascalchi, M., Morita, M. E., Pariente, J. C., Rodríguez-cruces, R., Rummel, C., Saavalainen, T., Semmelroch, M. K., Severino, M., Thomas, R. H., Tondelli, M., Tortora, D., Guerrini, R., Ourselin, S. & Richardson, M. P., 30 Jan 2018, In: Brain. 141, 2, p. 391-408

Research output: Contribution to journal › Article › peer-review

Open Access

File

260 Citations (Scopus)

52 Downloads (Pure)

2017

Automated tractography in patients with temporal lobe epilepsy using TRActs Constrained by UnderLying Anatomy (TRACULA)

Kreilkamp, B. A. K., Weber, B., Richardson, M. P. & Keller, S. S., 5 Jan 2017, (E-pub ahead of print) In: NeuroImage: Clinical. 14, p. 67-76 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

20 Citations (Scopus)

235 Downloads (Pure)

2016

Hippocampal internal architecture and postoperative seizure outcome in temporal lobe epilepsy due to hippocampal sclerosis

Elkommos, S., Weber, B., Niehusmann, P., Volmering, E., Richardson, M. P., Goh, Y. Y., Marson, A. G., Elger, C. & Keller, S. S., 1 Feb 2016, In: Seizure. 35, p. 65-71 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

9 Citations (Scopus)

157 Downloads (Pure)

2015

Morphometric MRI alterations and postoperative seizure control in refractory temporal lobe epilepsy

Keller, S. S., Richardson, M. P., O'Muircheartaigh, J., Schoene-Bake, J-C., Elger, C. & Weber, B., 2015, (E-pub ahead of print) In: Human Brain Mapping. 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Citations (Scopus)

Thalamotemporal alteration and postoperative seizures in temporal lobe epilepsy

Keller, S. S., Richardson, M. P., Schoene-Bake, J-C., O'Muircheartaigh, J., Elkommos, S., Kreilkamp, B., Goh, Y. Y., Marson, A. G., Elger, C. & Weber, B., 20 Apr 2015, In: Annals of Neurology. 77, 5, p. 760-774 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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89 Citations (Scopus)

134 Downloads (Pure)

2014

Thalamotemporal impairment in temporal lobe epilepsy: A combined MRI analysis of structure, integrity, and connectivity

Keller, S. S., O'Muircheartaigh, J., Traynor, C., Towgood, K., Barker, G. J. & Richardson, M. P., Feb 2014, In: Epilepsia. 55, 2, p. 306–315

Research output: Contribution to journal › Article › peer-review

Open Access

File

55 Citations (Scopus)

152 Downloads (Pure)

2012

Concomitant Fractional Anisotropy and Volumetric Abnormalities in Temporal Lobe Epilepsy: Cross-Sectional Evidence for Progressive Neurologic Injury

Keller, S. S., Schoene-Bake, J-C., Gerdes, J. S., Weber, B. & Deppe, M., 11 Oct 2012, In: PL o S One . 7, 10, p. - 12 p., e46791.

Research output: Contribution to journal › Article › peer-review

81 Citations (Scopus)

CONVERGENT EVIDENCE OF REGIONAL THALAMIC ABNORMALITIES IN MESIAL TEMPORAL LOBE EPILEPSY

Keller, S. S., Traynor, C., O'Muircheartaigh, J., Barker, G. J., Crum, W. & Richardson, M. P., Sept 2012, In: Epilepsia. 53, p. 59-59 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Early microstructural white matter changes in patients with HIV: A diffusion tensor imaging study

Stubbe-Draeger, B., Deppe, M., Mohammadi, S., Keller, S. S., Kugel, H., Gregor, N., Evers, S., Young, P., Ringelstein, E-B., Arendt, G., Knecht, S., Husstedt, I. W. & German Competence Network HIV AIDS, 1 May 2012, In: BMC Neurology. 12, p. - 10 p., 23.

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Variability and asymmetry of the sulcal contours defining Broca's area homologue in the chimpanzee brain

Keller, S. S., Deppe, M., Herbin, M. & Gilissen, E., 15 Apr 2012, In: Journal of Comparative Neurology. 520, 6, p. 1165 - 1180 16 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Volume Estimation of the Thalamus Using Freesurfer and Stereology: Consistency between Methods

Keller, S. S., Gerdes, J. S., Mohammadi, S., Kellinghaus, C., Kugel, H., Deppe, K., Ringelstein, E. B., Evers, S., Schwindt, W. & Deppe, M., Oct 2012, In: Neuroinformatics. 10, 4, p. 341-350 10 p.

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

2011

Microstructural and volumetric abnormalities of the putamen in juvenile myoclonic epilepsy

Keller, S. S., Ahrens, T., Mohammadi, S., Möddel, G., Kugel, H., Ringelstein, E. B. & Deppe, M., Sept 2011, In: Epilepsia. 52, 9, p. 1715-24 10 p.

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)

2009

A comparative magnetic resonance imaging study of the anatomy, variability, and asymmetry of Broca's area in the human and chimpanzee brain

Keller, S. S., Roberts, N. & Hopkins, W., 18 Nov 2009, In: Journal of Neuroscience. 29, 46, p. 14607-16 10 p.

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Broca's area: nomenclature, anatomy, typology and asymmetry

Keller, S. S., Crow, T., Foundas, A., Amunts, K. & Roberts, N., Apr 2009, In: Brain and Language. 109, 1, p. 29-48 20 p.

Research output: Contribution to journal › Article › peer-review

176 Citations (Scopus)

Quantitative MRI of the prefrontal cortex and executive function in patients with temporal lobe epilepsy

Keller, S. S., Baker, G., Downes, J. J. & Roberts, N., Jun 2009, In: Epilepsy & Behavior. 15, 2, p. 186-95 10 p.

Research output: Contribution to journal › Article › peer-review

93 Citations (Scopus)

2008

Nerve fiber impairment of anterior thalamocortical circuitry in juvenile myoclonic epilepsy

Deppe, M., Kellinghaus, C., Duning, T., Möddel, G., Mohammadi, S., Deppe, K., Schiffbauer, H., Kugel, H., Keller, S. S., Ringelstein, E. B. & Knecht, S., 9 Dec 2008, In: Neurology. 71, 24, p. 1981-5 5 p.

Research output: Contribution to journal › Article › peer-review

112 Citations (Scopus)

2002

Voxel-based morphometric comparison of hippocampal and extrahippocampal abnormalities in patients with left and right hippocampal atrophy

Keller, S. S., Mackay, C. E., Barrick, T. R., Wieshmann, U. C., Howard, M. A. & Roberts, N., May 2002, In: NeuroImage. 16, 1, p. 23-31 9 p.

Research output: Contribution to journal › Article › peer-review

169 Citations (Scopus)

Simon Keller

Research output

Search results