King's College London

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Dr Sophie Sayers

  1. Carnosine protects stimulus-secretion coupling through prevention of protein carbonyl adduction events in cells under metabolic stress

    Lavilla, C. J., Billacura, M. P., Hanna, K., Boocock, D. J., Coveney, C., Miles, A. K., Foulds, G. A., Murphy, A., Tan, A., Jackisch, L., Sayers, S. R., Caton, P. W., Doig, C. L., McTernan, P. G., Colombo, S. L., Sale, C. & Turner, M. D., 1 Nov 2021, In: Free Radical Biology and Medicine. 175, p. 65-79 15 p.

    Research output: Contribution to journalArticlepeer-review

  2. Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome

    Evans, E., Sayers, S., Kodji, X., Xia, Y., Shaikh, M., Rizvi, A., Frame, J., Brain, S., Philpott, M., Hannen, R. & Caton, P., Nov 2020, In: Molecular Metabolism. 41, 101047.

    Research output: Contribution to journalArticlepeer-review

  3. Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes

    Sayers, S. R., Beavil, R. L., Fine, N. H. F., Huang, G. C., Choudhary, P., Pacholarz, K. J., Barran, P. E., Butterworth, S., Mills, C. E., Cruickshank, J. K., Silvestre, M. P., Poppitt, S. D., McGill, A. T., Lavery, G. G., Hodson, D. J. & Caton, P. W., Feb 2020, In: Diabetologia. 63, 2, p. 313-323 11 p.

    Research output: Contribution to journalArticlepeer-review

  4. Identification of a subset of trace amine-associated receptors and ligands as potential modulators of insulin secretion

    Cripps, M. J., Bagnati, M., Jones, T. A., Ogunkolade, B. W., Sayers, S. R., Caton, P. W., Hanna, K., Billacura, M. P., Fair, K., Nelson, C., Lowe, R., Hitman, G. A., Berry, M. D. & Turner, M. D., 1 Jan 2020, In: Biochemical Pharmacology. 171, 113685.

    Research output: Contribution to journalArticlepeer-review

  5. Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake

    Cripps, M. J., Hanna, K., Lavilla, C., Sayers, S., Caton, P., Sims, C., De Girolamo, L., Sale, C. & Turner, M. D., 17 Oct 2017, (E-pub ahead of print) In: Scientific Reports. 7, 1, 13313.

    Research output: Contribution to journalArticlepeer-review

  6. Monomeric eNAMPT in the development of experimental diabetes in mice: a potential target for type 2 diabetes treatment

    Kieswich, J., Sayers, S. R., Silvestre, M., harwood, S., Yaqoob, M. & Caton, P. W., Nov 2016, In: Diabetologia. 59, 11

    Research output: Contribution to journalArticlepeer-review

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