Research output per year
Research output per year
Personal profile
Research interests
Antipsychotic drug action in animal models and translational work using PET imaging. Several receptor and molecular target systems involved in antipsychotic drug effects is the focus of the research. This work is carried out under the supervisio of Prof. Shitij Kapur
Research interests (short)
Mechanism of action of antipsychotics in preclinical models involving pharmacological, behavioural, determination of brain receptor occupancy, immunohistochemical & neuroimaging techniques.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Birla Institute of Technology and Science Pilani
Award Date: 1 Jan 2000
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Correction: Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study (Molecular Imaging and Biology, (2023), 25, 6, (1054-1062), 10.1007/s11307-023-01865-y)
Petty, A., Garcia-Hidalgo, A., Halff, E. F., Natesan, S., Withers, D. J., Irvine, E. E., Kokkinou, M., Wells, L. A., Bonsall, D. R., Tang, S. P., Veronese, M. & Howes, O. D., Jun 2024, In: Molecular Imaging and Biology. 26, 3, p. 553 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Synaptic Terminal Density Early in the Course of Schizophrenia: An In Vivo UCB-J Positron Emission Tomographic Imaging Study of SV2A
Onwordi, E. C., Whitehurst, T., Shatalina, E., Mansur, A., Arumuham, A., Osugo, M., Marques, T. R., Jauhar, S., Gupta, S., Mehrotra, R., Rabiner, E. A., Gunn, R. N., Natesan, S. & Howes, O. D., 1 Apr 2024, In: Biological psychiatry. 95, 7, p. 639-646 8 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study
Petty, A., Garcia-Hidalgo, A., Halff, E. F., Natesan, S., Withers, D. J., Irvine, E. E., Kokkinou, M., Wells, L. A., Bonsall, D. R., Tang, S. P., Veronese, M. & Howes, O. D., Dec 2023, In: Molecular Imaging and Biology. 25, 6, p. 1054-1062 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Synaptic Terminal Density Early in the Course of Schizophrenia: an in vivo UCB-J Positron Emission Tomographic Imaging Study of Synaptic Vesicle Glycoprotein 2A (SV2A)
Onwordi, E. C., Whitehurst, T., Shatalina, E., Mansur, A., Arumuham, A., Osugo, M., Reis Marques, T., Jauhar, S., Gupta, S., Mehrotra, R., Rabiner, E. A., Gunn, R. N., Natesan, S. & Howes, O., 23 May 2023, (Accepted/In press) In: Biological psychiatry.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Downloads (Pure) -
Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity
Halff, E. F., Natesan, S., Bonsall, D. R., Veronese, M., Garcia-Hidalgo, A., Kokkinou, M., Tang, S. P., Riggall, L. J., Gunn, R. N., Irvine, E. E., Withers, D. J., Wells, L. A. & Howes, O. D., 2022, In: Molecular Imaging. 2022, 4419221.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus)
Projects
- 3 Finished
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How antipsychotics work and why they fail - understanding the dynamics of antipsychotic action
Muller, C., Kapur, S. & Natesan, S.
1/07/2010 → 30/06/2013
Project: Research
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Understanding post-receptor mechanisms of antipsychotic action
Arranz, M., Fernandes, C., Kapur, S. & Natesan, S.
1/07/2010 → 30/06/2013
Project: Research