King's College London

Research portal

Dr Steven Niederer

  1. Cardiac CT assessment of tissue thickness at the ostium of the left atrial appendage predicts acute success of radiofrequency ablation

    Whitaker, J., Panikker, S., Fastl, T., Corrado, C., Virmani, R., Kutys, R., Lim, E., O'Neill, M., Nicol, E., Niederer, S. & Wong, T. 1 Nov 2017 In : Pacing and clinical electrophysiology : PACE. 40, 11, p. 1218-1226 9 p.

    Research output: Contribution to journalArticle

  2. Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model

    Neic, A., Campos, F. O., Prassl, A. J., Niederer, S. A., Bishop, M. J., Vigmond, E. J. & Plank, G. 1 Oct 2017 In : JOURNAL OF COMPUTATIONAL PHYSICS. 346, p. 191-211 21 p.

    Research output: Contribution to journalArticle

  3. A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

    Kuepfer, L. , Clayton, O. , Thiel, C. , Cordes, H. , Nudischer, R. , Blank, L. M. , Baier, V. , Heymans, S. , Caiment, F. , Roth, A. , Fluri, D. A. , Kelm, J. M. , Castell, J. , Selevsek, N. , Schlapbach, R. , Keun, H. , Hynes, J. , Sarkans, U. , Gmuender, H. , Herwig, R. & 4 others Niederer, S., Schuchhardt, J., Segall, M. & Kleinjans, J. 29 Aug 2017 In : Archives of Toxicology. p. 1-3 3 p.

    Research output: Contribution to journalArticle

  4. Cardiac computational modeling of ventricular tachycardia and cardiac resynchronization therapy: A clinical perspective

    Chen, Z., Niederer, S., Shanmugam, N., Sermesant, M. & Rinaldi, C. A. 1 Aug 2017 In : Minerva Cardioangiologica. 65, 4, p. 380-397 18 p.

    Research output: Contribution to journalReview article

  5. Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation

    Ribba, B., Grimm, H. P., Agoram, B., Davies, M. R., Gadkar, K., Niederer, S., van Riel, N., Timmis, J. & van der Graaf, P. H. 6 Jun 2017 In : CPT: Pharmacometrics and Systems Pharmacology.

    Research output: Contribution to journalArticle

  6. Restitution slope is principally determined by steady-state action potential duration

    Shattock, M. J., Park, K. C., Yang, H-Y., Lee, A. W. C., Niederer, S., MacLeod, K. T. & Winter, J. Jun 2017 In : Cardiovascular Research. 113, 7, p. 817–828 12 p., cvx063

    Research output: Contribution to journalArticle

  7. Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding

    Gattoni, S., Treu Røe, Å., Aronsen, J. M., Sjaastad, I., Louch, W. E., Smith, N. P. & Niederer, S. A. 21 May 2017 In : The Journal of physiology.

    Research output: Contribution to journalArticle

  8. Comprehensive use of cardiac computed tomography to guide left ventricular lead placement in cardiac resynchronization therapy

    Behar, J. M., Rajani, R., Pourmorteza, A., Preston, R., Razeghi, O., Niederer, S., Adhya, S., Claridge, S., Jackson, T., Sieniewicz, B., Gould, J., Carr-White, G., Razavi, R., McVeigh, E. & Rinaldi, C. A. 4 May 2017 In : Heart Rhythm. 14, 9, p. 1364-1372 9 p.

    Research output: Contribution to journalArticle

  9. A predictive patient specific model for the human atrium

    Corrado, C., Williams, S., Plank, G., O'Neill, M. & Niederer, S. May 2017 CMBE 2017 Proceedings. Nithiarasu, P. & Robertson, A. (eds.). Vol. 2, p. 972-975 4 p. (CMBE series; vol. 2017, no. 2)

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  10. Personalised biophysical model to optimize left ventricle pacing location for Cardiac Resynchronisation Therapy over time

    Lee, A., Sohal, M., Behar, J., Claridge, S., Shetty, A., Jackson, T., Hyde, E., Plank, G., Razavi, R., Lamata, P., Rinaldi, C. A. & Niederer, S. 1 Mar 2017 Computing in Cardiology. IEEE Computer Society Press, Vol. 43, p. 757-759 3 p. 7868853

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  11. Personalized modeling pipeline for left atrial electromechanics

    Fastl, T., Tobon Gomez, C., Crozier, W. A., Whitaker, J., Rajani, R., McCarthy, K. P., Sanchez-Quintana, D., Ho, S. Y., O'Neill, M., Plank, G., Bishop, M. J. & Niederer, S. 1 Mar 2017 Computing in Cardiology Conference, CinC 2016. IEEE Computer Society, Vol. 43, p. 225-228 4 p. 7868720

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  12. Accepted/In press
  13. Accepted/In press
  14. The calcium-frequency response in the rat ventricular myocyte: an experimental and modelling study

    Gattoni, S., Røe, Å. T., Frisk, M., Louch, W. E., Niederer, S. A. & Smith, N. P. 1 Aug 2016 In : The Journal of physiology. 594, 15, p. 4193-4224 32 p.

    Research output: Contribution to journalArticle

  15. The role of myocardial wall thickness in atrial arrhythmogenesis

    Whitaker, J., Rajani, R., Chubb, H., Gabrawi, M., Varela, M., Wright, M., Niederer, S. & O'Neill, M. D. 31 May 2016 In : EUROPACE. 18, 12, p. 1758-1772 15 p.

    Research output: Contribution to journalArticle

  16. Anatomically accurate high resolution modeling of human whole heart electromechanics: A strongly scalable algebraic multigrid solver method for nonlinear deformation

    Augustin, C. M., Neic, A., Liebmann, M., Prassl, A. J., Niederer, S. A., Haase, G. & Plank, G. 15 Jan 2016 In : JOURNAL OF COMPUTATIONAL PHYSICS. 305, p. 622-646 25 p.

    Research output: Contribution to journalArticle

  17. Image-Based Personalization of Cardiac Anatomy for Coupled Electromechanical Modeling

    Crozier, A., Augustin, C. M., Neic, A., Prassl, A. J., Holler, M., Fastl, T. E., Hennemuth, A., Bredies, K., Kuehne, T., Bishop, M. J., Niederer, S. A. & Plank, G. Jan 2016 In : Annals of Biomedical Engineering. 44, 1, p. 58-70

    Research output: Contribution to journalArticle

  18. Predicting Spiral Wave Stability by Personalized Electrophysiology models

    Corrado, C., Whitaker, J., Chubb, H., Williams, S., Wright, M., Gill, J., O'Neill, M. & Niederer, S. 2016 Computing In Cardiology 2016. Murray, A. (ed.). IEEE, Vol. 43, p. 229-232 4 p.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  19. Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour

    Land, S. , Gurev, V. , Arens, S. , Augustin, C. M. , Baron, L. , Blake, R. , Bradley, C. , Castro, S. , Crozier, W. A. , Favino, M. , Fastl, T. E. , Fritz, T. , Gao, H. , Gizzi, A. , Griffith, B. E. , Hurtado, D. E. , Krause, R. , Luo, X. , Nash, M. P. , Pezzuto, S. & 11 others Plank, G., Rossi, S., Ruprecht, D., Seemann, G., Smith, N. P., Sundnes, J., Rice, J. J., Trayanova, N., Wang, D., Wang, Z. J. & Niederer, S. A. 16 Dec 2015 In : Proceeding of the Royal Society A. 471, p. 1-20 20 p., 20150641

    Research output: Contribution to journalArticle

  20. CrossTalk opposing view: Physiological CO2 exchange does not normally depend on membrane channels

    Hulikova, A., Vaughan-Jones, R. D., Niederer, S. A. & Swietach, P. 1 Dec 2015 In : The Journal of physiology. 593, 23, p. 5029-5032 4 p.

    Research output: Contribution to journalArticle

  21. Rebuttal from Pawel Swietach, Richard D. Vaughan-Jones, Alzbeta Hulikova and Steven A. Niederer

    Swietach, P., Vaughan-Jones, R. D., Hulikova, A. & Niederer, S. A. 1 Dec 2015 In : The Journal of physiology. 593, 23, p. 5035 1 p.

    Research output: Contribution to journalArticle

  22. Factors determining the magnitude of the pre-ejection leftward septal motion in left bundle branch block

    Remme, E. W., Niederer, S., Gjesdal, O., Russell, K., Hyde, E. R., Smith, N. & Smiseth, O. A. 26 Nov 2015 In : EUROPACE. 18, 12, p. 1905-1913

    Research output: Contribution to journalArticle

  23. The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study

    Crozier, A., Blazevic, B., Lamata, P., Plank, G., Ginks, M., Duckett, S., Sohal, M., Shetty, A., Rinaldi, C. A., Razavi, R., Smith, N. P. & Niederer, S. A. 4 Nov 2015 In : Journal of Molecular and Cellular Cardiology.

    Research output: Contribution to journalArticle

  24. Factors influencing left ventricular outflow tract obstruction following a mitral valve-in-valve or valve-in-ring procedure, part 1

    Bapat, V., Pirone, F., Kapetanakis, S., Rajani, R. & Niederer, S. 1 Oct 2015 In : CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 86, 4, p. 747-760 14 p.

    Research output: Contribution to journalArticle

  25. Myocardial stiffness estimation: A novel cost function for unique parameter identification

    Nasopoulou, A., Blazevic, B., Crozier, A., Shi, W., Shetty, A., Aldo Rinaldi, C., Lamata, P. & Niederer, S. 21 Jun 2015 Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Springer-Verlag Berlin Heidelberg, Vol. 9126, p. 355-363 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9126)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  26. Personalization of atrial electrophysiology models from decapolar catheter measurements

    Corrado, C., Williams, S., Chubb, H., O’neill, M. & Niederer, S. A. 21 Jun 2015 Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Springer-Verlag Berlin Heidelberg, Vol. 9126, p. 21-28 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9126)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  27. Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+,K+-ATPase α2 activity

    Aronsen, J. M., Skogestad, J., Lewalle, A., Louch, W. E., Hougen, K., Stokke, M. K., Swift, F., Niederer, S., Smith, N. P., Sejersted, O. M. & Sjaastad, I. 15 Mar 2015 In : The Journal of Physiology. 593, 6, p. 1509-1521 13 p.

    Research output: Contribution to journalArticle

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