King's College London

Research portal

Dr Steven Niederer

  1. A short history of the development of mathematical models of cardiac mechanics

    Niederer, S. A., Campbell, K. S. & Campbell, S. G., Feb 2019, In : Journal of Molecular and Cellular Cardiology. 127, p. 11-19 9 p., 127.

    Research output: Contribution to journalArticle

  2. Determinants of new wavefront locations in cholinergic atrial fibrillation

    Roney, C. H., Ng, F. S., Debney, M. T., Eichhorn, C., Nachiappan, A., Chowdhury, R. A., Qureshi, N. A., Cantwell, C. D., Tweedy, J. H., Niederer, S. A., Peters, N. S. & Vigmond, E. J., 23 Nov 2018, In : Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. p. iii3–iii15

    Research output: Contribution to journalArticle

  3. Accepted/In press
  4. Accepted/In press
  5. Is the rapidly paced pig the optimal model for endocardial cardiac resynchronization therapy

    Niederer, S. A., Gould, J., Sieniewicz, B., Prinzen, F. & Rinaldi, C. A., 1 Jul 2018, In : Europace. 20, 7, p. 1227-1228 2 p.

    Research output: Contribution to journalLetter

  6. Personalized computational modeling of left atrial geometry and transmural myofiber architecture

    Fastl, T. E., Tobon-Gomez, C., Crozier, A., Whitaker, J., Rajani, R., McCarthy, K. P., Sanchez-Quintana, D., Ho, S. Y., O'Neill, M. D., Plank, G., Bishop, M. J. & Niederer, S. A., 1 Jul 2018, In : Medical Image Analysis. 47, p. 180-190 11 p.

    Research output: Contribution to journalArticle

  7. Unraveling the Underlying Arrhythmia Mechanism in Persistent Atrial Fibrillation: Results From the STARLIGHT Study

    Child, N., Clayton, R. H., Roney, C. H., Laughner, J. I., Shuros, A., Neuzil, P., Petru, J., Jackson, T., Porter, B., Bostock, J., Niederer, S. A., Razavi, R. S., Rinaldi, C. A., Taggart, P., Wright, M. J. & Gill, J., Jun 2018, In : Circulation. Arrhythmia and electrophysiology. 11, 6, p. e005897

    Research output: Contribution to journalArticle

  8. Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling

    Verheijen, M., Schrooders, Y., Gmuender, H., Nudischer, R., Clayton, O., Hynes, J., Niederer, S., Cordes, H., Kuepfer, L., Kleinjans, J. & Caiment, F., 24 May 2018, In : Toxicology Letters.

    Research output: Contribution to journalArticle

  9. Electrical latency predicts the optimal left ventricular endocardial pacing site: Results from a multicentre international registry

    Sieniewicz, B. J., Behar, J. M., Sohal, M., Gould, J., Claridge, S., Porter, B., Niederer, S., Gamble, J. H. P., Betts, T. R., Jais, P., Derval, N., Spragg, D. D., Steendijk, P., van Gelder, B. M., Bracke, F. A. & Rinaldi, C. A., 23 Apr 2018, In : Europace. 20, 12, p. 1989-1996 8 p.

    Research output: Contribution to journalArticle

  10. Lesion Index-Guided Ablation Facilitates Continuous, Transmural, and Durable Lesions in a Porcine Recovery Model

    Whitaker, J., Fish, J., Harrison, J., Chubb, H., Williams, S. E., Fastl, T., Corrado, C., Van Zaen, J., Gibbs, J., O'Neill, L., Mukherjee, R., Rittey, D., Thorsten, J., Donskoy, E., Sohal, M., Rajani, R., Niederer, S., Wright, M. & O'Neill, M. D., Apr 2018, In : Circulation. Arrhythmia and electrophysiology. 11, 4, p. e005892

    Research output: Contribution to journalArticle

  11. Decreasing compensatory ability of concentric ventricular hypertrophy in aortic-banded rat hearts

    Lewalle, A., Land, S., Carruth, E., Frank, L. R., Lamata, P., Omens, J. H., McCulloch, A. D., Niederer, S. A. & Smith, N. P., 23 Feb 2018, In : Frontiers in Physiology. 9

    Research output: Contribution to journalArticle

  12. Accepted/In press

    An asymmetric wall-thickening pattern predicts response to Cardiac Resynchronization Therapy

    Warriner, D. R., Jackson, T., Zacur, E., Sammut, E., Sheridan, P., Hose, DR., Lawford, P. V., Razavi, R., Niederer, S. A., Rinaldi, C. A. & Lamata, P., 19 Jan 2018, (Accepted/In press) In : JACC Cardiovascular Imaging.

    Research output: Contribution to journalLetter

  13. Analytical approaches for myocardial fibrillation signals

    Handa, B. S., Roney, C. H., Houston, C., Qureshi, N. A., Li, X., Pitcher, D. S., Chowdhury, R. A., Lim, P. B., Dupont, E., Niederer, S. A., Cantwell, C. D., Peters, N. S. & Ng, F. S., 2018, In : Computers in Biology and Medicine.

    Research output: Contribution to journalArticle

  14. Cardiac CT assessment of tissue thickness at the ostium of the left atrial appendage predicts acute success of radiofrequency ablation

    Whitaker, J., Panikker, S., Fastl, T., Corrado, C., Virmani, R., Kutys, R., Lim, E., O'Neill, M., Nicol, E., Niederer, S. & Wong, T., 1 Nov 2017, In : Pacing and clinical electrophysiology : PACE. 40, 11, p. 1218-1226 9 p.

    Research output: Contribution to journalArticle

  15. Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model

    Neic, A., Campos, F. O., Prassl, A. J., Niederer, S. A., Bishop, M. J., Vigmond, E. J. & Plank, G., 1 Oct 2017, In : JOURNAL OF COMPUTATIONAL PHYSICS. 346, p. 191-211 21 p.

    Research output: Contribution to journalArticle

  16. A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

    Kuepfer, L., Clayton, O., Thiel, C., Cordes, H., Nudischer, R., Blank, L. M., Baier, V., Heymans, S., Caiment, F., Roth, A., Fluri, D. A., Kelm, J. M., Castell, J., Selevsek, N., Schlapbach, R., Keun, H., Hynes, J., Sarkans, U., Gmuender, H., Herwig, R. & 4 othersNiederer, S., Schuchhardt, J., Segall, M. & Kleinjans, J., 29 Aug 2017, In : Archives of Toxicology. p. 1-3 3 p.

    Research output: Contribution to journalArticle

  17. Cardiac computational modeling of ventricular tachycardia and cardiac resynchronization therapy: A clinical perspective

    Chen, Z., Niederer, S., Shanmugam, N., Sermesant, M. & Rinaldi, C. A., 1 Aug 2017, In : Minerva Cardioangiologica. 65, 4, p. 380-397 18 p.

    Research output: Contribution to journalReview article

  18. Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation

    Ribba, B., Grimm, HP., Agoram, B., Davies, MR., Gadkar, K., Niederer, S., van Riel, N., Timmis, J. & van der Graaf, PH., 6 Jun 2017, In : CPT: Pharmacometrics and Systems Pharmacology.

    Research output: Contribution to journalArticle

  19. Restitution slope is principally determined by steady-state action potential duration

    Shattock, M. J., Park, K. C., Yang, H-Y., Lee, A. W. C., Niederer, S., MacLeod, K. T. & Winter, J., Jun 2017, In : Cardiovascular Research. 113, 7, p. 817–828 12 p., cvx063.

    Research output: Contribution to journalArticle

  20. Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding

    Gattoni, S., Treu Røe, Å., Aronsen, J. M., Sjaastad, I., Louch, W. E., Smith, N. P. & Niederer, S. A., 21 May 2017, In : The Journal of physiology.

    Research output: Contribution to journalArticle

  21. Comprehensive use of cardiac computed tomography to guide left ventricular lead placement in cardiac resynchronization therapy

    Behar, J. M., Rajani, R., Pourmorteza, A., Preston, R., Razeghi, O., Niederer, S., Adhya, S., Claridge, S., Jackson, T., Sieniewicz, B., Gould, J., Carr-White, G., Razavi, R., McVeigh, E. & Rinaldi, C. A., 4 May 2017, In : Heart Rhythm. 14, 9, p. 1364-1372 9 p.

    Research output: Contribution to journalArticle

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