King's College London

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Dr Steven Niederer

  1. Accepted/In press
  2. Accepted/In press
  3. Is the rapidly paced pig the optimal model for endocardial cardiac resynchronization therapy

    Niederer, S. A., Gould, J., Sieniewicz, B., Prinzen, F. & Rinaldi, C. A. 1 Jul 2018 In : Europace. 20, 7, p. 1227-1228 2 p.

    Research output: Contribution to journalLetter

  4. Personalized computational modeling of left atrial geometry and transmural myofiber architecture

    Fastl, T. E., Tobon-Gomez, C., Crozier, A., Whitaker, J., Rajani, R., McCarthy, K. P., Sanchez-Quintana, D., Ho, S. Y., O'Neill, M. D., Plank, G., Bishop, M. J. & Niederer, S. A. 1 Jul 2018 In : Medical Image Analysis. 47, p. 180-190 11 p.

    Research output: Contribution to journalArticle

  5. Unraveling the Underlying Arrhythmia Mechanism in Persistent Atrial Fibrillation: Results From the STARLIGHT Study

    Child, N., Clayton, R. H., Roney, C. H., Laughner, J. I., Shuros, A., Neuzil, P., Petru, J., Jackson, T., Porter, B., Bostock, J., Niederer, S. A., Razavi, R. S., Rinaldi, C. A., Taggart, P., Wright, M. J. & Gill, J. Jun 2018 In : Circulation. Arrhythmia and electrophysiology. 11, 6, p. e005897

    Research output: Contribution to journalArticle

  6. Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling

    Verheijen, M., Schrooders, Y., Gmuender, H., Nudischer, R., Clayton, O., Hynes, J., Niederer, S., Cordes, H., Kuepfer, L., Kleinjans, J. & Caiment, F. 24 May 2018 In : Toxicology Letters.

    Research output: Contribution to journalArticle

  7. Lesion Index-Guided Ablation Facilitates Continuous, Transmural, and Durable Lesions in a Porcine Recovery Model

    Whitaker, J., Fish, J., Harrison, J., Chubb, H., Williams, S. E., Fastl, T., Corrado, C., Van Zaen, J., Gibbs, J., O'Neill, L., Mukherjee, R., Rittey, D., Thorsten, J., Donskoy, E., Sohal, M., Rajani, R., Niederer, S., Wright, M. & O'Neill, M. D. Apr 2018 In : Circulation. Arrhythmia and electrophysiology. 11, 4, p. e005892

    Research output: Contribution to journalArticle

  8. Decreasing compensatory ability of concentric ventricular hypertrophy in aortic-banded rat hearts

    Lewalle, A., Land, S., Carruth, E., Frank, L. R., Lamata , P., Omens, J. H., McCulloch, A. D., Niederer, S. A. & Smith, N. P. 23 Feb 2018 In : Frontiers in Physiology. 9

    Research output: Contribution to journalArticle

  9. Accepted/In press

    An asymmetric wall-thickening pattern predicts response to Cardiac Resynchronization Therapy

    Warriner, D. R., Jackson, T. A., Zacur, E., Sammut, E. C., Sheridan, P., Hose, DR., Lawford, P. V., Razavi, R., Niederer, S. A., Rinaldi, C. A. & Lamata de la Orden, P. 19 Jan 2018 (Accepted/In press) In : JACC Cardiovascular Imaging.

    Research output: Contribution to journalArticle

  10. Analytical approaches for myocardial fibrillation signals

    Handa, B. S., Roney, C. H., Houston, C., Qureshi, N. A., Li, X., Pitcher, D. S., Chowdhury, R. A., Lim, P. B., Dupont, E., Niederer, S. A., Cantwell, C. D., Peters, N. S. & Ng, F. S. 2018 In : Computers in Biology and Medicine.

    Research output: Contribution to journalArticle

  11. Cardiac CT assessment of tissue thickness at the ostium of the left atrial appendage predicts acute success of radiofrequency ablation

    Whitaker, J., Panikker, S., Fastl, T., Corrado, C., Virmani, R., Kutys, R., Lim, E., O'Neill, M., Nicol, E., Niederer, S. & Wong, T. 1 Nov 2017 In : Pacing and clinical electrophysiology : PACE. 40, 11, p. 1218-1226 9 p.

    Research output: Contribution to journalArticle

  12. Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model

    Neic, A., Campos, F. O., Prassl, A. J., Niederer, S. A., Bishop, M. J., Vigmond, E. J. & Plank, G. 1 Oct 2017 In : JOURNAL OF COMPUTATIONAL PHYSICS. 346, p. 191-211 21 p.

    Research output: Contribution to journalArticle

  13. A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

    Kuepfer, L. , Clayton, O. , Thiel, C. , Cordes, H. , Nudischer, R. , Blank, L. M. , Baier, V. , Heymans, S. , Caiment, F. , Roth, A. , Fluri, D. A. , Kelm, J. M. , Castell, J. , Selevsek, N. , Schlapbach, R. , Keun, H. , Hynes, J. , Sarkans, U. , Gmuender, H. , Herwig, R. & 4 others Niederer, S., Schuchhardt, J., Segall, M. & Kleinjans, J. 29 Aug 2017 In : Archives of Toxicology. p. 1-3 3 p.

    Research output: Contribution to journalArticle

  14. Cardiac computational modeling of ventricular tachycardia and cardiac resynchronization therapy: A clinical perspective

    Chen, Z., Niederer, S., Shanmugam, N., Sermesant, M. & Rinaldi, C. A. 1 Aug 2017 In : Minerva Cardioangiologica. 65, 4, p. 380-397 18 p.

    Research output: Contribution to journalReview article

  15. Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation

    Ribba, B., Grimm, HP., Agoram, B., Davies, MR., Gadkar, K., Niederer, S., van Riel, N., Timmis, J. & van der Graaf, PH. 6 Jun 2017 In : CPT: Pharmacometrics and Systems Pharmacology.

    Research output: Contribution to journalArticle

  16. Restitution slope is principally determined by steady-state action potential duration

    Shattock, M. J., Park, K. C., Yang, H-Y., Lee, A. W. C., Niederer, S., MacLeod, K. T. & Winter, J. Jun 2017 In : Cardiovascular Research. 113, 7, p. 817–828 12 p., cvx063

    Research output: Contribution to journalArticle

  17. Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding

    Gattoni, S., Treu Røe, Å., Aronsen, J. M., Sjaastad, I., Louch, W. E., Smith, N. P. & Niederer, S. A. 21 May 2017 In : The Journal of physiology.

    Research output: Contribution to journalArticle

  18. Comprehensive use of cardiac computed tomography to guide left ventricular lead placement in cardiac resynchronization therapy

    Behar, J. M., Rajani, R., Pourmorteza, A., Preston, R., Razeghi, O., Niederer, S., Adhya, S., Claridge, S., Jackson, T., Sieniewicz, B., Gould, J., Carr-White, G., Razavi, R., McVeigh, E. & Rinaldi, C. A. 4 May 2017 In : Heart Rhythm. 14, 9, p. 1364-1372 9 p.

    Research output: Contribution to journalArticle

  19. A predictive patient specific model for the human atrium

    Corrado, C., Williams, S., Plank, G., O'Neill, M. & Niederer, S. May 2017 CMBE 2017 Proceedings. Nithiarasu, P. & Robertson, A. (eds.). Vol. 2, p. 972-975 4 p. (CMBE series; vol. 2017, no. 2)

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  20. Personalised biophysical model to optimize left ventricle pacing location for Cardiac Resynchronisation Therapy over time

    Lee, A., Sohal, M., Behar, J., Claridge, S., Shetty, A., Jackson, T., Hyde, E., Plank, G., Razavi, R., Lamata, P., Rinaldi, C. A. & Niederer, S. 1 Mar 2017 Computing in Cardiology. IEEE Computer Society Press, Vol. 43, p. 757-759 3 p. 7868853

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  21. Personalized modeling pipeline for left atrial electromechanics

    Fastl, T., Tobon Gomez, C., Crozier, W. A., Whitaker, J., Rajani, R., McCarthy, K. P., Sanchez-Quintana, D., Ho, S. Y., O'Neill, M., Plank, G., Bishop, M. J. & Niederer, S. 1 Mar 2017 Computing in Cardiology Conference, CinC 2016. IEEE Computer Society, Vol. 43, p. 225-228 4 p. 7868720

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  22. Accepted/In press
  23. A predictive personalised model for the left atrium

    Corrado, C., Williams, S., Planck, G., O'Neill, M. & Niederer, S. 1 Jan 2017 In : Computing in Cardiology. 44, p. 1-4 4 p.

    Research output: Contribution to journalConference paper

  24. Probabilistic models for integration error in the assessment of functional cardiac models

    Oates, C. J., Niederer, S., Lee, A., Briol, F. X. & Girolami, M. 1 Jan 2017 In : ADVANCES IN NEURAL INFORMATION PROCESSING SYSTEMS. 2017-December, p. 110-118 9 p.

    Research output: Contribution to journalConference paper

  25. A platform for quantifying atrial structural remodelling

    Razeghi, O., Karim, R., Whitaker, J., Tobon-Gomez, C. & Niederer, S. 2017 In : Computing in Cardiology. 44, p. 1-4 4 p.

    Research output: Contribution to journalConference paper

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