Research output per year
Research output per year
Personal profile
Biographical details
Dr. Steven Niederer completed his undergraduate degree in Engineering Science at the University of Auckland and received his DPhil in computer science from the University of Oxford in 2008. Dr Niederer was a UK Engineering and Physical Sciences Research Council (EPSRC) Life Sciences Interface Early Career Fellow at Oxford prior to moving to Kings’ College London where he is currently a senior lecturer in the Division of Imaging Sciences and Biomedical Engineering.
Research interests
Dr Niederer’s research aims to combine experimental and clinical data with biophysical computational models to better understand cardiac physiology and pathology to better inform patient selection, treatment and therapy optimisation. This work currently focuses on understanding the cellular and tissue scale physiology that underpin the short and long term response to pacemakers in patients, developing detailed biophysical models of the rat and mouse heart linking subcellular physiology to whole organ function, developing simulations of atria electrophysiology and mechanics to investigate atrial fibrillation and using models of cardiac myocytes to investigate cardiotoxicity.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, A coupled electromechanics model of the rat left ventricle, University of Oxford
Award Date: 1 Jan 2008
Bachelor of Engineering, University of Auckland
Award Date: 1 Jan 2004
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Computational Modelling Enabling In Silico Trials for Cardiac Physiologic Pacing
Strocchi, M., Wijesuriya, N., Mehta, V., de Vere, F., Rinaldi, C. A. & Niederer, S. A., Jun 2024, In: Journal of cardiovascular translational research. 17, 3, p. 685-694 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Enhancing transvenous lead extraction risk prediction: Integrating imaging biomarkers into machine learning models
Mehta, V. S., Ma, Y. L., Wijesuriya, N., DeVere, F., Howell, S., Elliott, M. K., Mannkakara, N. N., Hamakarim, T., Wong, T., O'Brien, H., Niederer, S., Razavi, R. & Rinaldi, C. A., Jun 2024, In: Heart rhythm : the official journal of the Heart Rhythm Society. 21, 6, p. 919-928 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)35 Downloads (Pure) -
Evaluation of deep learning estimation of whole heart anatomy from automated cardiovascular magnetic resonance short- and long-axis analyses in UK Biobank
Muffoletto, M., Xu, H., Burns, R., Suinesiaputra, A., Nasopoulou, A., Kunze, K. P., Neji, R., Petersen, S. E., Niederer, S. A., Rueckert, D. & Young, A. A., 1 Oct 2024, In: European Heart Journal Cardiovascular Imaging. 25, 10, p. 1374-1383 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Heart Size Difference Drives Sex-Specific Response to Cardiac Resynchronization Therapy: A Post Hoc Analysis of the MORE-MPP CRT Trial
Wijesuriya, N., Mehta, V., De Vere, F., Howell, S., Niederer, S. A., Burri, H., Sperzel, J., Calo, L., Thibault, B., Lin, W., Lee, K., Grammatico, A., Varma, N., Gwechenberger, M., Leclercq, C. & Rinaldi, C. A., 18 Jun 2024, In: Journal of the American Heart Association. 13, 12, p. e035279 e035279.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Optimizing electrical efficacy of leadless cardiac resynchronization therapy and leadless left ventricular septal pacing: insights on left and right ventricular activation from electrocardiographic imaging
Wijesuriya, N., Strocchi, M., Elliott, M., Mehta, V., De Vere, F., Howell, S., Mannakkara, N., Niederer, S. & Rinaldi, C. A., Aug 2024, In: Heart Rhythm O2. 5, 8, p. 551-560 10 p.Research output: Contribution to journal › Article › peer-review
Open Access
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Alan Turing Institute - Professor Niederer Digital Twin Secondment Salary Costs
Niederer, S. (Primary Investigator)
1/11/2022 → 31/12/2025
Project: Research
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Feasibility and proposed mechanisms for effective leadless left ventricular endocardial conduction system pacing
academic, A. (Primary Investigator) & Niederer, S. (Co-Investigator)
5/10/2022 → 4/10/2025
Project: Research
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Investigating Mechanisms of Alcohol-Induced Heart Disease
Niederer, S. (Primary Investigator)
NHMRC National Health & Medical Research Council
1/06/2022 → 30/09/2025
Project: Research
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Selecting Rhythm or Rate Control in Patients with both Atrial Fibrillation and Heart Failure
Niederer, S. (Primary Investigator), Bishop, M. (Co-Investigator) & Ismail, T. (Co-Investigator)
1/10/2020 → 30/09/2025
Project: Research
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PREDICT-HF: Predicting Outcome of Rate or Rhythm Control in Patients with Atrial Fibrillation and Heart Failure
Niederer, S. (Primary Investigator)
1/09/2020 → 31/08/2025
Project: Research
Datasets
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Personalized computational finite element models for left atrial electromechanics
Fastl, T., Tobon Gomez, C., Crozier, A., Whitaker, J., Rajani, R., McCarthy, K. P., Sanchez-Quintana, D., Ho, S. Y., O'Neill, M., Plank, G., Bishop, M. & Niederer, S., King's College London, 9 Apr 2018
DOI: 10.18742/rdm01-289, https://kcl.figshare.com/articles/dataset/Personalized_computational_finite_element_models_for_left_atrial_electromechanics/16473780
Dataset
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A Virtual Cohort of Twenty-four Left-ventricular Models of Ischemic Cardiomyopathy Patients
Mendonca Costa, C., Neic, A., Kerfoot, E., Gillette, K., Porter, B., Sieniewicz, B., Gould, J., Sidhu, B., Chen, Z., Elliott, M., Mehta, V., Plank, G., Rinaldi, C. A., Bishop, M. & Niederer, S., King's College London, 28 Feb 2020
DOI: 10.18742/rdm01-570, https://kcl.figshare.com/articles/dataset/A_Virtual_Cohort_of_Twenty-four_Left-ventricular_Models_of_Ischemic_Cardiomyopathy_Patients/16473903
Dataset
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Constructing a Human Atrial Fibre Atlas
Roney, C., Bendikas, R., Pashakhanloo, F., Corrado, C., Vigmond, E., McVeigh, E., Trayanova, N. & Niederer, S., King's College London, 27 Apr 2020
DOI: 10.18742/rdm01-596, https://kcl.figshare.com/articles/dataset/Constructing_a_Human_Atrial_Fibre_Atlas/16473906
Dataset
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A Publicly Available Virtual Cohort of Four-chamber Heart Meshes for Cardiac Electro-mechanics Simulations
Strocchi, M., Augustin, C. M., Gsell, M. A. F., Karabelas, E., Neic, A., Gillette, K., Razeghi, O., Prassl, A. J., Vigmond, E. J., Behar, J., Gould, J., Sidhu, B., Rinaldi, C. A., Bishop, M., Plank, G. & Niederer, S., Zenodo, 15 Jun 2020
DOI: 10.5281/zenodo.3890034, https://zenodo.org/record/3890034
Dataset