Projects per year
Projects
- 64 Finished
- 1 - 50 out of 64 results
Search results
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Finished
UKRI CoA: The influence of TRPA1 signalling on the response to cold exposure as ageing occurs
Brain, S. (Primary Investigator)
EPSRC Engineering and Physical Sciences Research Council
1/01/2021 → 30/09/2021
Project: Research
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Characterisation of RASA3 interaction with integrin andcytoskeletal protein in platelets
Brain, S. (Co-Investigator) & Authi, K. (Primary Investigator)
20/01/2020 → 19/09/2023
Project: Research
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Elucidating the protective potential of calcitonin gene-related peptide (CGRP) in cardiovascular disease
Brain, S. (Primary Investigator)
1/10/2019 → 30/06/2023
Project: Research
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Investigating the vascular response to a cold probe: a study of mechanisms in cardiovascular health & disease
Brain, S. (Primary Investigator) & Gnudi, L. (Co-Investigator)
1/10/2019 → 30/09/2022
Project: Research
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TRPA1- inflammasome signalling in temporomandibular joint inflammatory pain
Brain, S. (Primary Investigator)
4/09/2017 → 3/09/2019
Project: Research
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Transient Receptor Potential Canonical 5 (TRPC5), a missing link in osteoarthritic pain and inflammation
Brain, S. (Primary Investigator) & Williams, F. (Co-Investigator)
1/07/2017 → 31/12/2020
Project: Research
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The influence of TRPA1signalling on the response to cold exposure as ageing occurs
Brain, S. (Primary Investigator) & Andersson, D. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/06/2017 → 31/07/2020
Project: Research
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Determining a role for TRPC5 in cholestasis associated cardiovascular dysfunction
Brain, S. (Primary Investigator) & Williamson, C. (Co-Investigator)
1/10/2016 → 30/09/2019
Project: Research
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Elucidating the protective potential of calcitonin gene- related peptide (CGRP) at different sites in cardiovascular disease
Brain, S. (Primary Investigator) & Aubdool, A. (Co-Investigator)
1/02/2016 → 31/01/2019
Project: Research
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The mechanisms involved in the local and systemic influence of TRP channels that act as vascular cold sensor
Brain, S. (Primary Investigator) & Andersson, D. (Co-Investigator)
1/01/2016 → 31/12/2018
Project: Research
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MICA: Development and Characterization of Intracellular Calcitonin Gene-Related Peptide Receptor Antagonists for the Treatment of Migraine
Brain, S. (Primary Investigator)
1/03/2015 → 28/02/2018
Project: Research
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Investigating the role of TRPA1 and sensory nerves interaction with the cutaneous vasculature and keratinocytes in a skin inflammation model
Brain, S. (Primary Investigator)
British Pharmacological Society
1/10/2014 → 30/09/2016
Project: Research
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The role of TRPA1-dependent vascular responses in environmental cooling and influence of ageing
Brain, S. (Primary Investigator) & Andersson, D. (Co-Investigator)
1/10/2013 → 30/09/2016
Project: Research
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Refining an established model of hypertension in the mouse
Brain, S. (Primary Investigator)
NC3Rs National Centre for the Replacement, Refinement and Reduction of Animals in Research
1/10/2013 → 30/09/2016
Project: Research
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Transient receptor potential canonical (TRPC) 5: role in joint pain and inflammation
Brain, S. (Primary Investigator)
1/02/2013 → 13/04/2017
Project: Research
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a novel role for the TRPV1 antagonist AZD1386 in obesity-induced hypertension under conditions associated with stress
Brain, S. (Primary Investigator) & O'Byrne, K. (Co-Investigator)
24/01/2013 → 23/01/2015
Project: Research
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Does CGRP play a pivotal protective role in vascular inflammation and is it a potential therapeutic target?
Brain, S. (Primary Investigator)
1/07/2012 → 28/09/2015
Project: Research
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Does CGRP play a pivotal protective role in vascular inflammation and is it a potential therapeutic target?
Brain, S. (Primary Investigator) & Sams, A. (Co-Investigator)
1/01/2012 → 31/12/2014
Project: Research
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TRPC5-a new target molecule to enhance protection to pain in arthritis?
Brain, S. (Primary Investigator)
1/01/2012 → 31/12/2017
Project: Research
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Development of a blood gene expression assay to identify intracranial aneurysms
Brain, S. (Primary Investigator) & academic, A. (Primary Investigator)
1/01/2012 → 31/12/2013
Project: Research
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Transient receptor potential (TRP) channels and vascular smooth muscle: regulatory mechanisms
Brain, S. (Primary Investigator) & McFadzean, I. (Primary Investigator)
1/10/2011 → 30/09/2014
Project: Research
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Identification of genes associated with resistance to hypertension in high-fat fed transient receptor potential vanilloid 1 TRPV1 knockout mouse
O'Dell, S. (Primary Investigator), Brain, S. (Co-Investigator) & Hogstrand, C. (Co-Investigator)
1/07/2011 → 30/06/2014
Project: Research
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Identification of genes associated with resistance to hypertension in high-fat fed transient receptor potential vanilloid 1 TRPV1 knockout mouse
Brain, S. (Primary Investigator), O'Dell, S. (Primary Investigator) & Hogstrand, C. (Co-Investigator)
1/01/2011 → 31/12/2013
Project: Research
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Refinement of a rodent model of septic shock
Brain, S. (Primary Investigator), Nandi, M. (Primary Investigator), Channon, K. (Co-Investigator), Leiper, J. (Co-Investigator) & academic, A. (Co-Investigator)
1/11/2010 → 31/10/2012
Project: Research
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Detection of gene expression associated with susceptibility to diet-induced obesity using multiple mouse models
Brain, S. (Primary Investigator), Hogstrand, C. (Primary Investigator) & O'Dell, S. (Primary Investigator)
1/10/2010 → 30/09/2013
Project: Research
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Elucidating the role of TRPA1 and TRPV1 in vascular inflammation and pain
Brain, S. (Primary Investigator)
British Pharmacological Society
1/07/2010 → 31/05/2011
Project: Research
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Does endoglin modulate the angiogenic switch of TGFB signalling in systematic sclerosis?
Aaronson, P. (Primary Investigator), Brain, S. (Primary Investigator), Howat, S. (Primary Investigator), Abraham, D. (Co-Investigator) & Denton, C. (Co-Investigator)
Raynaud's and Scleroderma Association
1/07/2010 → 31/07/2011
Project: Research
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Investigations of the potential protective role of calculation gene-related peptide (CGRP) in hypertension
Brain, S. (Primary Investigator) & academic, A. (Primary Investigator)
University of London Central Research Fund
1/07/2010 → 30/06/2011
Project: Research
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Bringing systems biology to the Centre of Integrative Biomedicine at King's College London
Brain, S. (Primary Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/06/2010 → 30/09/2013
Project: Research
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Role of PIM-1 kinase in the survival of OxLDL loaded macrophages
academic, A. (Primary Investigator), Brain, S. (Co-Investigator) & Mann, G. (Co-Investigator)
1/01/2010 → 31/12/2011
Project: Research
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Elucidating the role of TRPA1 in modulating joint inflammation and pain
Brain, S. (Primary Investigator), Keeble, J. (Co-Investigator) & Malcangio, M. (Co-Investigator)
1/11/2009 → 7/02/2014
Project: Research
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The Arthritis Pain Research Centre at King's College London
McMahon, S. (Primary Investigator), Bevan, S. (Co-Investigator), Brain, S. (Co-Investigator), Choy, E. (Co-Investigator), Malcangio, M. (Co-Investigator), Spector, T. (Co-Investigator), Williams, S. (Co-Investigator) & Williams, F. (Co-Investigator)
1/10/2009 → 30/09/2014
Project: Research
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Investigation of hypothalamic gene expression in response to standard and high-fat diets in mice susceptible and resistant to diet-induced obesity
O'Dell, S. (Primary Investigator) & Brain, S. (Co-Investigator)
1/10/2009 → 30/09/2012
Project: Research
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Industrial Impact Fellowship in Drug Discovery
Christie, M. (Primary Investigator), Page, C. (Primary Investigator), Brain, S. (Co-Investigator), Cox, H. (Co-Investigator), Duty, S. (Co-Investigator), Keeble, J. (Co-Investigator), Malcangio, M. (Co-Investigator), Patel, J. (Co-Investigator) & Thomas, S. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/10/2009 → 31/12/2013
Project: Research
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Conference: 7th international symposia on the CGRP family; CGRP, Adrenomedullin, Amylin, Intermedin and Calcitonin
Brain, S. (Primary Investigator)
23/08/2009 → 4/09/2010
Project: Research
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The vasoactive and inflammatory potential of TRP receptors in the peripheral microvasculature
Brain, S. (Primary Investigator)
1/07/2009 → 30/06/2011
Project: Research
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Elucidating mechanisms by which TRPV1 plays a protective mechanism in sepsis
Brain, S. (Primary Investigator) & Keeble, J. (Primary Investigator)
1/04/2009 → 31/03/2012
Project: Research
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Mechanisms involved in the accumulation and contribution of CD64-bearing neutrophils to systemic inflammation in murine models of sepsis
Brain, S. (Primary Investigator), Brown, K. (Co-Investigator) & Keeble, J. (Co-Investigator)
1/04/2009 → 31/03/2012
Project: Research
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The anti-inflammatory and pro-inflammatory effects of TRPV1 receptors: Implications for the treatment of joint disease
Howat, S. (Primary Investigator), Keeble, J. (Primary Investigator), Brain, S. (Co-Investigator), Moore, P. (Co-Investigator) & Pearson, J. (Co-Investigator)
1/01/2009 → 31/12/2011
Project: Research
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Role of hydrogen sulphide (h2s) in arthritis: manipulation of the endogenous cysteine: h2s pathway as a novel approach to the treatment of arthritis
Brain, S. (Primary Investigator), Keeble, J. (Primary Investigator) & Moore, P. (Primary Investigator)
1/01/2009 → 31/12/2011
Project: Research
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BHF Centre of Research Excellence
Avkiran, M. (Primary Investigator), Blower, P. (Primary Investigator), Botnar, R. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Eaton, P. (Primary Investigator), Ehler, E. (Primary Investigator), Garcia-Manyes, S. (Primary Investigator), Gautel, M. (Primary Investigator), Geissmann, F. (Primary Investigator), Hussain, M. (Primary Investigator), Irving, M. (Primary Investigator), Kalra, L. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Nagel, E. (Primary Investigator), Otsu, K. (Primary Investigator), Razavi, R. (Primary Investigator), Ridley, A. (Primary Investigator), Shah, A. (Primary Investigator), Shanahan, C. (Primary Investigator), Smith, N. (Primary Investigator), Xu, Q. (Primary Investigator), Alastruey, J. (Co-Investigator), Ameer-Beg, S. (Co-Investigator), Bishop, M. (Co-Investigator), Brain, S. (Co-Investigator), Burgoyne, J. (Co-Investigator), Conte, M. (Co-Investigator), Dhanjal, T. (Co-Investigator), Eminaga, S. (Co-Investigator), Eykyn, T. (Co-Investigator), Gee, T. (Co-Investigator), Heintzmann, R. (Co-Investigator), Hughes, S. (Co-Investigator), Iskratsch, T. (Co-Investigator), Ivetic, A. (Co-Investigator), Jones, G. E. (Co-Investigator), Kentish, J. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Lombardi, G. (Co-Investigator), Mullen, G. (Co-Investigator), Okonko, D. (Co-Investigator), Parsons, M. (Co-Investigator), Pfuhl, M. (Co-Investigator), Phinikaridou, A. (Co-Investigator), Rodaway, A. (Co-Investigator), Shattock, M. (Co-Investigator), Sinkus, R. (Co-Investigator), Springett, R. (Co-Investigator), Steiner, R. (Co-Investigator), Stroud, M. (Co-Investigator), Sun, Y.-B. (Co-Investigator), Wardle, F. (Co-Investigator), Warren, D. (Co-Investigator), Webb, A. (Co-Investigator), Zampetaki, A. (Co-Investigator), Zeng, L. (Co-Investigator) & academic, A. (Co-Investigator)
1/01/2008 → 31/03/2019
Project: Research
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Centre for Integrative Biomedicine
Brain, S. (Primary Investigator), Cox, H. (Primary Investigator), Duty, S. (Primary Investigator), Flatters, S. (Primary Investigator), Keeble, J. (Primary Investigator), King, A. (Primary Investigator), Malcangio, M. (Primary Investigator), McFadzean, I. (Primary Investigator), McMahon, S. (Primary Investigator), Moon, L. (Primary Investigator), Moore, P. (Primary Investigator), Spina, D. (Primary Investigator), Thomas, S. (Primary Investigator), Gibson, A. (Co-Investigator), Howell, S. (Co-Investigator), Mountford, D. (Co-Investigator) & O'Dell, S. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
4/03/2007 → 30/09/2013
Project: Research
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Does the TRPV1 receptor play a role in maintaining vasodilator tone?
Brain, S. (Primary Investigator)
1/10/2006 → 30/09/2009
Project: Research
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TRP1 and cardiovascular biology
Brain, S. (Primary Investigator)
1/05/2006 → 30/09/2009
Project: Research
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Investigating mechanisms involved in the interplay between TNF and TRPV1 that governs inflammatory hyperalgesia.
Brain, S. (Primary Investigator)
1/05/2006 → 30/04/2009
Project: Research
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Characterisation Of The Receptor-Mediated Mechanisms That Underlie The Protective Effects Of Endogenous Adrenomedullin In Cardiovascular Hypertrophy
Brain, S. (Primary Investigator)
1/10/2004 → 30/09/2007
Project: Research
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The influence of microvascular mechanisms on neuronal activity in inflammatory disease
Brain, S. (Primary Investigator)
1/10/2004 → 30/09/2007
Project: Research
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Stress-Induced Reproductive Dysfunction: a novel neural action for calcitonin gene-related peptide
Brain, S. (Primary Investigator), O'Byrne, K. (Primary Investigator) & Li, X. (Co-Investigator)
1/08/2004 → 31/07/2007
Project: Research
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The influence of adrenomedullin, calcitonin gene-related peptide (CGRP) and their receptors on mechanisms involved in sepsis
Brain, S. (Primary Investigator)
1/07/2003 → 30/06/2006
Project: Research