Research output per year
Research output per year
The main focus of work in my research group is in identifying new targets for improving the treatment of Parkinson's disease. Targets of especial interest include metabotropic glutamate receptors which are present in key regions of the basal ganglia circuitry where they work to regulate neurotransmitter release from overactive pathways. Such targets may offer an alternative route to symptom relief and neuroprotection in this debilitating disease. We are also interested in finding ways to encourage repair of the damaged nigrostriatal tract. Current targets of interest in this capacity are growth factors like FGF20 and we are currently examining ways in which to boost brain levels of FGF20 in order to provide protection and repair to dopaminergic neurones in Parkinson's. We use a range of molecular, cellular and whole system approaches to address these issues.
New strategies for improving the treatment of Parkinson's disease.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Philosophy, University of Manchester
Award Date: 1 Jan 1990
Bachelor of Science, University of Manchester
Award Date: 1 Jan 1987
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Bannister, K. (Primary Investigator), Duty, S. (Co-Investigator), McMahon, S. (Co-Investigator) & Ray Chaudhuri, K. (Co-Investigator)
15/09/2021 → 17/03/2024
Project: Research
Duty, S. (Primary Investigator)
EPSRC Engineering and Physical Sciences Research Council
1/09/2020 → 18/12/2020
Project: Research
Duty, S. (Primary Investigator)
1/03/2019 → 31/08/2020
Project: Research
Duty, S. (Primary Investigator)
19/01/2019 → 19/09/2021
Project: Research
Malcangio, M. (Primary Investigator), Duty, S. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Ray Chaudhuri, K. (Co-Investigator)
1/08/2018 → 31/07/2022
Project: Research