Research output per year
Research output per year
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Dive into the research topics where Thomas Kampourakis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Discovery of Novel Cardiac Troponin Activators using Fluorescence Polarization-based High Throughput Screening Assays
Parijat, P., Ponnam, S., Attili, S., Campbell, K., El-Mezgueldi, M., Pfuhl, M. & Kampourakis, T., 28 Mar 2023, (Accepted/In press) In: Scientific Reports.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Downloads (Pure) -
In situ FRET-based localization of the N-terminus of myosin binding protein-C in heart muscle cells
Chandler, J., Treacy, C., Ameer-Beg, S., Ehler, E., Irving, M. & Kampourakis, T., 21 Mar 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 12, e2222005120.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)69 Downloads (Pure) -
Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7
Cai, F., Kampourakis, T., Cockburn, K. T. & Sykes, B. D., 17 Jun 2022, In: Acs Chemical Biology. 17, 6, p. 1495-1504 10 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Phosphorylation-dependent interactions of myosin binding protein-C and troponin coordinate the myofilament response to Protein Kinase A
Sevrieva, I., Ponnam, S., Yan, Z., Irving, M., Kampourakis, T. & Sun, Y-B., 1 Dec 2022, (Accepted/In press) In: Journal of Biological Chemistry.Research output: Contribution to journal › Article › peer-review
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A Potent Fluorescent Reversible-Covalent Inhibitor of Cardiac Muscle Contraction
Cai, F., Kampourakis, T., Klein, B. A. & Sykes, B. D., 9 Sept 2021, In: Acs Medicinal Chemistry Letters. 12, 9, p. 1503-1507 5 p.Research output: Contribution to journal › Article › peer-review
Projects
- 6 Finished
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A cryo-electron microscope for structural biology (including single-particle and tomography) at KCL.
Conte, M., Atherton, J., Beavil, A., Bergeron, J., Booth, P., Burrone, J., Carlton, J., De Nicola, G., Ehler, E., Fleck, R., Fraternali, F., Garnett, J., Gautel, M., Isaacson, R., Kampourakis, T., Malim, M., McDonnell, J., Neil, S., Odendall, C., Pfuhl, M., Politis, A., Steiner, R. & Sutton, B.
BBSRC Biotechnology and Biological Sciences Research Council
1/08/2022 → 31/07/2023
Project: Research
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Isothermal titration calorimetry instrumentation for structural biology, biological mechanisms and drug discovery
Conte, M., Gautel, M., McDonnell, J., Isaacson, R., Barry, S., Garnett, J., Steiner, R., Muller, M., Pfuhl, M., Bergeron, J., Malim, M., Naglik, J., Kampourakis, T., Burgoyne, J., Pastore, A. & De Nicola, G.
BBSRC Biotechnology and Biological Sciences Research Council
1/10/2020 → 30/09/2021
Project: Research
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Kampourakis,: Length-Dependent Activation in Human Myocardium
NIH National Institutes of Health
15/09/2020 → 31/07/2023
Project: Research
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Targeting the myofilaments to correct heart muscle dysfunction
1/09/2019 → 31/08/2022
Project: Research
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Cardiac thick filament modulators: A potential new class of heart failure therapeutics
1/10/2017 → 31/12/2018
Project: Research