Research output per year
Research output per year
Personal profile
Research interests
I use the UK twins registry (TWINSUK) of 10,000 twins to pursue gene discovery in the common complex traits and diseases via genetic epidemiology. I study a wide variety of diseases from back pain to anxiety, snoring to sexuality. Our group focus on age related diseases such as CVD, metabolic traits, locomotor problems such as osteoporosis and osteoarthritis, cognitive function and eye disorders.We have genomewide scans and expression data on large numbers of the twins.
Research interests (short)
Genetic epidemiology; twin studies; chronic complex trait genetics; CVD; metabolic; ageing; Microbiome, locomotor
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Characterisation of Fasting and Postprandial NMR Metabolites: Insights from the ZOE PREDICT 1 Study
Bermingham, K. M., Mazidi, M., Franks, P. W., Maher, T., Valdes, A. M., Linenberg, I., Wolf, J., Hadjigeorgiou, G., Spector, T. D., Menni, C., Ordovas, J. M., Berry, S. E. & Hall, W. L., Jun 2023, In: Nutrients. 15, 11, 2638.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic and gut microbiome determinants of SCFA circulating and faecal levels, postprandial responses and links to chronic and acute inflammation
Nogal, A., Asnicar, F., Vijay, A., Kouraki, A., Visconti, A., Louca, P., Wong, K., Baleanu, A-F., Giordano, F., Wolf, J., Hadjigeorgiou, G., Davies, R., Michelotti, G. A., Franks, P. W., Berry, S., Falchi, M., Ikram, A., Ollivere, B. J., Zheng, A., Nightingale, J., & 6 others, 2023, In: Gut Microbes.Research output: Contribution to journal › Article › peer-review
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Interplay between the (Poly)phenol Metabolome, Gut Microbiome, and Cardiovascular Health in Women: A Cross-Sectional Study from the TwinsUK Cohort
Li, Y., Xu, Y., Le Roy, C., Hu, J., Steves, C. J., Bell, J. T., Spector, T. D., Gibson, R., Menni, C. & Rodriguez-Mateos, A., 14 Apr 2023, In: Nutrients. 15, 8, 1900.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Metabolomic and gut microbiome profiles across the spectrum of community-based COVID and non-COVID disease
Österdahl, M. F., Whiston, R., Sudre, C. H., Asnicar, F., Cheetham, N. J., Blanco Miguez, A., Bowyer, V., Antonelli, M., Snell, O., dos Santos Canas, L., Hu, C., Wolf, J., Menni, C., Malim, M., Hart, D., Spector, T., Berry, S., Segata, N., Doores, K., Ourselin, S., & 2 others, Dec 2023, In: Scientific Reports. 13, 1, 10407.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma protein N-glycome composition associates with postprandial lipaemic response
Louca, P., Štambuk, T., Frkatovic-Hodzic, A., Nogal MacHo, A., Mangino, M., Berry, S., Deriš, H., Hadjigeorgiou, G., Wolf, J., Vinicki, M., Franks, P. W., Valdes, AM., Spector, T., Lauc, G. & Menni, C., 2023, (Accepted/In press) In: BMC Medicine.Research output: Contribution to journal › Article › peer-review
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TwinsUK Imaging: A Resource for Ageing Research
Steves, C., Hajnal, J., Modat, M., Ourselin, S. & Spector, T.
Chronic Disease Research Foundation
1/11/2022 → 31/03/2028
Project: Research
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The COVID Symptom Study Application: Research Platform and Biobank
Ourselin, S., Brown, M., Doores, K., Duncan, E., Malim, M., Spector, T. & Steves, C.
Chronic Disease Research Foundation
1/12/2020 → 29/02/2024
Project: Research
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Emma Duncan_: The COVID Symptoms Study: The Genetics of Long COVID-19
Duncan, E., Ourselin, S. & Spector, T.
Chronic Disease Research Foundation
1/10/2020 → 29/02/2024
Project: Research
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Predicting Response to Immunotherapy for Melanoma with gut Microbiome and metabolomics – The PRIMM Study
1/10/2020 → 31/12/2023
Project: Research
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Creation of a Research Microbiome Laboratory Facility
Chronic Disease Research Foundation
15/08/2018 → 31/12/2023
Project: Research
Datasets
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DNA methylome analysis of human peripheral blood samples in cancer discordant monozygotic twin-pairs
Spector, T., Bell, J. & Roos, L., Gene Expression Omnibus, 25 Oct 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE89093
Dataset