Research output per year
Research output per year
Personal profile
Research interests
I use the UK twins registry (TWINSUK) of 10,000 twins to pursue gene discovery in the common complex traits and diseases via genetic epidemiology. I study a wide variety of diseases from back pain to anxiety, snoring to sexuality. Our group focus on age related diseases such as CVD, metabolic traits, locomotor problems such as osteoporosis and osteoarthritis, cognitive function and eye disorders.We have genomewide scans and expression data on large numbers of the twins.
Research interests (short)
Genetic epidemiology; twin studies; chronic complex trait genetics; CVD; metabolic; ageing; Microbiome, locomotor
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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MenoScale: a novel digital tool to measure menopause symptoms and subjective quality of life - validation, preliminary insights on the menopausal experience and association with diet quality
Kim, C., Marples, L., Bermingham, K., Platts, A., Amati, F., Hamoda, H., Pounis, G., Wolf, J., Spector, T., Hall, W. & Berry, S., 2 Apr 2025, (Accepted/In press) In: Post reproductive health.Research output: Contribution to journal › Article › peer-review
Open Access -
Quantification of heavy metal exposure in a British population cohort links total mercury levels in plasma with skin tissue-specific changes in mitochondrial-related gene expression
Van De Streek, M., Ali, A., El-Sayed Moustafa, J., Glastonbury, C., Spector, T., Valdes, A., Staff, J., Morton, J., Hodgkinson, A., Bell, J. & Small, K., 6 Jan 2025, (Accepted/In press) In: Science of the Total Environment.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Downloads (Pure) -
Symptom Evolution in Individuals with Ongoing Symptomatic COVID-19 and Post COVID-19 Syndrome After SARS-CoV-2 Vaccination Versus Influenza Vaccination
Rjoob, K., Antonelli, M., Murray, B., Molteni, E., Cheetham, N., Canas, L. S., Modat, M., Pujol, J. C., Hu, C., Bowyer, V., Wolf, J., Spector, T. D., Ourselin, S., Hammers, A., Duncan, E. L., Steves, C. J. & Sudre, C. H., 10 Jan 2025, (E-pub ahead of print) In: The Journal of infection. 90, 2, p. 106406 106406.Research output: Contribution to journal › Article › peer-review
Open Access -
Courage in decision-making: A mixed-methods study of COVID-19 vaccine uptake in women of reproductive age in the UK
Magee, L., Brown, J. R. B., Bowyer, V., Horgan, G., Boulding, H., Khalil, A., Cheetham, N., Harvey, N., The CSSB Study Group, The RESILIENT Study Group, Mistry, H., Sudre, C. H., Silverio, S. A., von Dadelszen, P. & Duncan, E., 18 Apr 2024, In: Vaccines. 12, 4, p. 1-16 440.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)145 Downloads (Pure) -
Cross-sectional analyses of metabolites across biological samples mediating dietary acid load and chronic kidney disease
Attaye, I., Beynon-Cobb, B., Louca, P., Nogal, A., Visconti, A., Tettamanzi, F., Wong, K., Michellotti, G., Spector, T. D., Falchi, M., Bell, J. T. & Menni, C., 15 Mar 2024, In: iScience. 27, 3, p. 109132 109132.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus)
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TwinsUK LPS: TwinsUK (2023-2028): An Epidemiological & Genomics Resource
Steves, C. (Primary Investigator), Hammond, C. (Co-Investigator), Hart, D. (Co-Investigator), Small, K. (Co-Investigator) & Spector, T. (Co-Investigator)
1/01/2024 → 31/12/2028
Project: Research
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TwinsUK Imaging: A Resource for Ageing Research
Steves, C. (Primary Investigator), Hajnal, J. (Co-Investigator), Modat, M. (Co-Investigator), Ourselin, S. (Co-Investigator) & Spector, T. (Co-Investigator)
Chronic Disease Research Foundation
1/11/2022 → 31/03/2028
Project: Research
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Emma Duncan_: The COVID Symptoms Study: The Genetics of Long COVID-19
Duncan, E. (Primary Investigator), Ourselin, S. (Co-Investigator) & Spector, T. (Co-Investigator)
Chronic Disease Research Foundation
1/10/2020 → 30/06/2025
Project: Research
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PROSPECT: PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
Bell, J. (Primary Investigator), Berry, S. (Co-Investigator), Spector, T. (Co-Investigator) & Steves, C. (Co-Investigator)
1/05/2024 → 30/04/2025
Project: Research
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PROSPECT: NCI - PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
Bell, J. (Primary Investigator), Berry, S. (Co-Investigator), Spector, T. (Co-Investigator) & Steves, C. (Co-Investigator)
NIH National Institutes of Health
1/05/2024 → 30/04/2025
Project: Research
Datasets
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DNA methylome analysis of human peripheral blood samples in cancer discordant monozygotic twin-pairs
Spector, T., Bell, J. & Roos, L., Gene Expression Omnibus, 25 Oct 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE89093
Dataset