Research output per year
Research output per year
Personal profile
Research interests
I use the UK twins registry (TWINSUK) of 10,000 twins to pursue gene discovery in the common complex traits and diseases via genetic epidemiology. I study a wide variety of diseases from back pain to anxiety, snoring to sexuality. Our group focus on age related diseases such as CVD, metabolic traits, locomotor problems such as osteoporosis and osteoarthritis, cognitive function and eye disorders.We have genomewide scans and expression data on large numbers of the twins.
Research interests (short)
Genetic epidemiology; twin studies; chronic complex trait genetics; CVD; metabolic; ageing; Microbiome, locomotor
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Courage in decision-making: A mixed-methods study of COVID-19 vaccine uptake in women of reproductive age in the UK
Magee, L., Brown, J. R. B., Bowyer, V., Horgan, G., Boulding, H., Khalil, A., Cheetham, N., Harvey, N., The CSSB Study Group, The RESILIENT Study Group, Mistry, H., Sudre, C. H., Silverio, S. A., von Dadelszen, P. & Duncan, E., 18 Apr 2024, In: Vaccines. 12, 4, p. 1-16 440.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)18 Downloads (Pure) -
Cross-sectional analyses of metabolites across biological samples mediating dietary acid load and chronic kidney disease
Attaye, I., Beynon-Cobb, B., Louca, P., Nogal, A., Visconti, A., Tettamanzi, F., Wong, K., Michellotti, G., Spector, T. D., Falchi, M., Bell, J. T. & Menni, C., 15 Mar 2024, In: iScience. 27, 3, p. 109132 109132.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Development of a (Poly)phenol Metabolic Signature for Assessing (Poly)phenol-Rich Dietary Patterns
Li, Y., Xu, Y., Le Sayec, M., Yan, X., Spector, T. D., Steves, C. J., Bell, J. T., Small, K. S., Menni, C., Gibson, R. & Rodriguez-Mateos, A., 12 Jun 2024, In: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 72, 23, p. 13439-13450 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial
Bermingham, K., Linenberg, I., Polidori, L., Asnicar, F., Arre, A., Wolf, J., Badri, F., Bernard, H., Capdevila, J., Bulsiewicz, W. J., Gardner, C. D., Ordovas, J. M., Davies, R., Hadjigeorgiou, G., Hall, W., Delahanty, L. M., Valdes, A., Segata, N., Spector, T. & Berry, S., 8 May 2024, In: Nature Medicine. 30, 7, p. 1888-1897 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)70 Downloads (Pure) -
Enhanced resolution profiling in twins reveals differential methylation signatures of Type 2 Diabetes with links to its complications
Christiansen, C., Potier, L., Martin, T. C., Villicana Munoz, S., Castillo Fernandez, J., Mangino, M., Menni, C., Tsai, P-C., Campbell, P. J., Mullin, S., Ordoñana, J. R., Monteagudo, O., Sachdev, P. S., Mather, K. A., Trollor, J. N., Pietiläinen, K. H., Ollikainen, M., Dalgård, C., Kyvik, K. O., Christensen, K., & 9 others, 2024, In: EBioMedicine. 103, 105096.Research output: Contribution to journal › Article › peer-review
Open Access
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PROSPECT: PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
Bell, J., Berry, S., Spector, T. & Steves, C.
1/05/2024 → 30/04/2025
Project: Research
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TwinsUK LPS: TwinsUK (2023-2028): An Epidemiological & Genomics Resource
Steves, C., Hammond, C., Hart, D., Small, K. & Spector, T.
1/01/2024 → 31/12/2028
Project: Research
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TwinsUK Imaging: A Resource for Ageing Research
Steves, C., Hajnal, J., Modat, M., Ourselin, S. & Spector, T.
Chronic Disease Research Foundation
1/11/2022 → 31/03/2028
Project: Research
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TwinsUKGWAS_: TwinsUK GWAS Programme
NIAID National Institute of Allergy and Infectious Diseases, National Institutes of Health
1/08/2021 → 31/07/2022
Project: Research
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NAF_Xu-jieZh: A multi-omics study to dissect the role of the gut microbiome in IgA nephropathy risk
1/03/2021 → 28/02/2024
Project: Research
Datasets
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DNA methylome analysis of human peripheral blood samples in cancer discordant monozygotic twin-pairs
Spector, T., Bell, J. & Roos, L., Gene Expression Omnibus, 25 Oct 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE89093
Dataset