King's College London

Research portal

Professor Toby Prevost

  1. Development and validation of predictive risk models for sight threatening diabetic retinopathy in patients with type 2 diabetes to be applied as triage tools in resource limited settings

    Nugawela, M. D., Gurudas, S., Prevost, A. T., Mathur, R., Robson, J., Sathish, T., Rafferty, J. M., Rajalakshmi, R., Anjana, R. M., Jebarani, S., Mohan, V., Owens, D. R. & Sivaprasad, S., Sep 2022, In: EClinicalMedicine. 51, 101578, 13 p., 101578.

    Research output: Contribution to journalArticlepeer-review

  2. Multicenter Evaluation of Diagnostic Circulating Biomarkers to Detect Sight-Threatening Diabetic Retinopathy

    Gurudas, S., Frudd, K., Maheshwari, J. J., Revathy, Y. R., Sivaprasad, S., Ramanathan, S. M., Pooleeswaran, V., Prevost, A. T., Karatsai, E., Halim, S., Chandra, S., Nderitu, P., Conroy, D., Krishnakumar, S., Parameswaran, S., Dharmalingam, K., Ramasamy, K., Raman, R., Jones, C., Eleftheriadis, H. & 2 others, Greenwood, J. & Turowski, P., Jun 2022, In: JAMA Ophthalmology. 140, 6, p. 587-597 11 p.

    Research output: Contribution to journalArticlepeer-review

  3. Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration-the PINNACLE trial protocol

    Sutton, J., Menten, M. J., Riedl, S., Bogunovic, H., Leingang, O., Anders, P., Hagag, A. M., Waldstein, S., Wilson, A., Cree, A. J., Traber, G., Fritsche, L. G., Scholl, H., Rueckert, D., Schmidt-Erfurth, U., Sivaprasad, S., Prevost, T. & Lotery, A., 25 May 2022, In: Eye (London, England). 9 p.

    Research output: Contribution to journalArticlepeer-review

  4. The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection—study protocol for a two-stage randomised phase II trial

    Lee, M. J., Collins, S., Babalis, D., Johnson, N., Falaschetti, E., Prevost, A. T., Ashraf, A., Jacob, M., Cole, T., Hurley, L., Pace, M., Ogbe, A., Khan, M., Zacharopoulou, P., Brown, H., Sutherland, E., Box, H., Fox, J., Deeks, S., Horowitz, J. & 4 others, Nussenzweig, M. C., Caskey, M., Frater, J. & Fidler, S., 5 Apr 2022, In: Trials. 23, 1, 26 p., 263.

    Research output: Contribution to journalReview articlepeer-review

  5. Adjusting for verification bias in diagnostic accuracy measures when comparing multiple screening tests - an application to the IP1-PROSTAGRAM study

    Day, E., Eldred-Evans, D., Prevost, A. T., Ahmed, H. U. & Fiorentino, F., 18 Mar 2022, In: BMC Medical Research Methodology. 22, 1, 70.

    Research output: Contribution to journalArticlepeer-review

  6. Feasibility of Comparative Health Research Outcome of Novel Surgery in prostate cancer (IP4-CHRONOS): statistical analysis plan for the randomised feasibility phase of the CHRONOS study

    Day, E., Prevost, A. T., Sydes, M. R., Reddy, D., Shah, T. T., Winkler, M., Dudderidge, T., Staffurth, J., McCracken, S., Khoo, V., Jadav, P., Klimowska-Nassar, N., Sasikaran, T., Ahmed, H. U. & Fiorentino, F., Dec 2021, In: Trials. 22, 1, 547.

    Research output: Contribution to journalArticlepeer-review

  7. Improving the interpretation of afternoon cortisol levels and SSTs to prevent misdiagnosis of adrenal insufficiency

    Ramadoss, V., Lazarus, K., Prevost, A. T., Tan, T., Meeran, K. & Choudhury, S., 1 Nov 2021, In: Journal of the Endocrine Society. 5, 11, bvab147.

    Research output: Contribution to journalArticlepeer-review

  8. Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial

    Farne, H., Glanville, N., Johnson, N., Kebadze, T., Aniscenko, J., Regis, E., Zhu, J., Trujillo-Torralbo, M-B., Kon, O. M., Mallia, P., Prevost, T., Rose, M. R., Edwards, M., Johnston, S., Singanayagam, A. & Jackson, D. J., 29 Oct 2021, (E-pub ahead of print) In: Thorax. 10 p., thoraxjnl-2021-217429.

    Research output: Contribution to journalArticlepeer-review

  9. Ethnic disparities in the development of sight-threatening diabetic retinopathy in a uk multi-ethnic population with diabetes: An observational cohort study

    Nugawela, M. D., Gurudas, S., Prevost, A. T., Mathur, R., Robson, J., Hanif, W., Majeed, A. & Sivaprasad, S., Aug 2021, In: Journal of Personalized Medicine. 11, 8, 740.

    Research output: Contribution to journalArticlepeer-review

  10. Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT

    Hykin, P., Prevost, A. T., Sivaprasad, S., Vasconcelos, J. C., Murphy, C., Kelly, J., Ramu, J., Alshreef, A., Flight, L., Pennington, R., Hounsome, B., Lever, E., Metry, A., Poku, E., Yang, Y., Harding, S. P., Lotery, A., Chakravarthy, U. & Brazier, J., 1 Jun 2021, In: Health technology assessment (Winchester, England). 25, 38, p. VII-111 196 p.

    Research output: Contribution to journalArticlepeer-review

  11. Randomised controlled trial of a just-in-time adaptive intervention (JITAI) smoking cessation smartphone app: The Quit Sense feasibility trial protocol

    Naughton, F., Brown, C., High, J., Notley, C., Mascolo, C., Coleman, T., Barton, G., Shepstone, L., Sutton, S., Prevost, A. T., Crane, D., Greaves, F. & Hope, A., 26 Apr 2021, In: BMJ Open. 11, 4, 48204.

    Research output: Contribution to journalComment/debatepeer-review

  12. The feasibility of the PAM intervention to support treatment-adherence in people with hypertension in primary care: a randomised clinical controlled trial

    Kassavou, A., Mirzaei, V., Shpendi, S., Brimicombe, J., Chauhan, J., Bhattacharya, D., Naughton, F., Hardeman, W., Eborall, H., Van Emmenis, M., De Simoni, A., Takhar, A., Gupta, P., Patel, P., Mascolo, C., Prevost, A. T., Morris, S., Griffin, S., McManus, R. J., Mant, J. & 1 others, Sutton, S., 26 Apr 2021, In: Scientific Reports. 11, 1, p. 8897 1 p.

    Research output: Contribution to journalArticlepeer-review

  13. Who will benefit from bariatric surgery for diabetes? A protocol for an observational cohort study

    Kenkre, J. S., Ahmed, A. R., Purkayastha, S., Malallah, K., Bloom, S., Blakemore, A. I., Prevost, A. T. & Tan, T., 10 Feb 2021, In: BMJ Open. 11, 2, 042355.

    Research output: Contribution to journalArticlepeer-review

  14. Protocol on a multicentre statistical and economic modelling study of risk-based stratified and personalised screening for diabetes and its complications in India (SMART India)

    Sivaprasad, S., Raman, R., Rajalakshmi, R., Mohan, V., Deepa, M., Das, T., Ramasamy, K., Prevost, A. T., Wittenberg, R., Netuveli, G., Lingam, G., Hanif, W., Ramakrishnan, R., Ramu, J., Surya, J. & Conroy, D., 12 Dec 2020, In: BMJ Open. 10, 12, 39657.

    Research output: Contribution to journalArticlepeer-review

  15. Association between high serum total cortisol concentrations and mortality from COVID-19

    Tan, T., Khoo, B., Mills, E. G., Phylactou, M., Patel, B., Eng, P. C., Thurston, L., Muzi, B., Meeran, K., Prevost, A. T., Comninos, A. N., Abbara, A. & Dhillo, W. S., Aug 2020, In: The Lancet Diabetes and Endocrinology. 8, 8, p. 659-660 2 p.

    Research output: Contribution to journalLetterpeer-review

  16. Evaluation of a very brief pedometer-based physical activity intervention delivered in NHS Health Checks in England: The VBI randomised controlled trial

    VBI Research Team, Hardeman, W., Mitchell, J., Pears, S., Van Emmenis, M., Theil, F., Gc, V. S., Vasconcelos, J. C., Westgate, K., Brage, S., Suhrcke, M., Griffin, S. J., Kinmonth, A. L., Wilson, E. C. F., Prevost, A. T. & Sutton, S., 6 Mar 2020, In: PLoS Medicine. 17, 3, p. e1003046 20 p., e1003046.

    Research output: Contribution to journalArticlepeer-review

  17. Clinical Effectiveness of Intravitreal Therapy with Ranibizumab vs Aflibercept vs Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion: A Randomized Clinical Trial

    Hykin, P., Prevost, A. T., Vasconcelos, J. C., Murphy, C., Kelly, J., Ramu, J., Hounsome, B., Yang, Y., Harding, S. P., Lotery, A., Chakravarthy, U. & Sivaprasad, S., 1 Nov 2019, In: JAMA Ophthalmology. 137, 11, p. 1256-1264 9 p.

    Research output: Contribution to journalArticlepeer-review

  18. Electronically delivered interventions to reduce antibiotic prescribing for respiratory infections in primary care: cluster RCT using electronic health records and cohort study

    Gulliford, M. C., Juszczyk, D., Prevost, A. T., Soames, J., McDermott, L., Sultana, K., Wright, M., Fox, R., Hay, A. D., Little, P., Moore, M., Yardley, L., Ashworth, M. & Charlton, J., Mar 2019, In: Health technology assessment (Winchester, England). 23, 11, p. 1-72 72 p.

    Research output: Contribution to journalArticlepeer-review

  19. Lightmasks that prevent dark adaptation for non-central diabetic macular oedema: the CLEOPATRA RCT

    Sivaprasad, S., Vasconcelos, J., Holmes, H., Murphy, C., Kelly, J., Hykin, P. & Prevost, A. T., Mar 2019, In: Efficacy and Mechanism Evaluation. 6, 2, p. 1-78

    Research output: Contribution to journalArticlepeer-review

  20. Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial

    Gulliford, M. C., Prevost, A. T., Charlton, J., Juszczyk, D., Soames, J., McDermott, L., Sultana, K., Wright, M., Fox, R., Hay, A. D., Little, P., Moore, M. V., Yardley, L. & Ashworth, M., Feb 2019, In: BMJ (Clinical research ed.). 364, l236.

    Research output: Contribution to journalArticlepeer-review

  21. Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

    Santhakumaran, S., Gordon, A., Prevost, A. T., O’Kane, C., McAuley, D. F. & Shankar-Hari, M., 2019, In: CRITICAL CARE. 23, 1, 156.

    Research output: Contribution to journalArticlepeer-review

  22. Intravitreal aflibercept compared with panretinal photocoagulation for proliferative diabetic retinopathy: the CLARITY non-inferiority RCT

    Sivaprasad, S., Hykin, P., Prevost, A. T., Vasconcelos, J., Riddell, A., Ramu, J., Murphy, C., Kelly, J., Edwards, R. T., Yeo, S. T., Bainbridge, J., Hopkins, D. & White-alao, B., 1 Oct 2018, In: Efficacy and Mechanism Evaluation. 5, 5, p. 1-112

    Research output: Contribution to journalArticlepeer-review

  23. Mechanistic evaluation of panretinal photocoagulation versus aflibercept in proliferative diabetic retinopathy: CLARITY substudy

    Nicholson, L., Crosby-Nwaobi, R., Vasconcelos, J. C., Prevost, A. T., Ramu, J., Riddell, A., Bainbridge, J. W., Hykin, P. G. & Sivaprasad, S., Aug 2018, In: Investigative Ophthalmology and Visual Science. 59, 10, p. 4277-4284 8 p.

    Research output: Contribution to journalArticlepeer-review

  24. Clinical efficacy and safety of a light mask for prevention of dark adaptation in treating and preventing progression of early diabetic macular oedema at 24 months (CLEOPATRA): a multicentre, phase 3, randomised controlled trial

    Sivaprasad, S., Vasconcelos, J. C., Prevost, A. T., Holmes, H., Hykin, P., George, S., Murphy, C., Kelly, J., Arden, G. B., Ahfat, F., Bhatnagar, A., Narendran, N., Chavan, R., Cole, A., Crosby-Nwaobi, R., Patrao, N., Menon, D., Hogg, C., Rubin, G., Leitch-Devlin, L. & 27 others, Egan, C., Shah, N., Mansour, T., Peto, T., Eleftheriadis, H., Gibson, J., Ghulakhszian, A., Vafidis, G., Hughes, E., Jafree, A., Menon, G., Prakash, P., Sandinha, M., Smith, R., Scanlon, P., Chave, S., Aldington, S., Dale, A., Hood, G., Hitman, G. A., Crabb, D., Denniston, A., Lewin, D., Grierson, I., Walker, S., Sturt, J. & Sahu, D., May 2018, In: Lancet diabetes & endocrinology. 6, 5, p. 382-391

    Research output: Contribution to journalArticlepeer-review

  25. Nutritional labelling for healthier food or non-alcoholic drink purchasing and consumption

    Crockett, R. A., King, S. E., Marteau, T. M., Prevost, A. T., Bignardi, G., Roberts, N. W., Stubbs, B., Hollands, G. J. & Jebb, S. A., 27 Feb 2018, In: The Cochrane database of systematic reviews. 10, 2, CD009315.

    Research output: Contribution to journalReview articlepeer-review

  26. Intravitreal aflibercept for proliferative diabetic retinopathy – Authors' reply

    Sivaprasad, S., Prevost, A. T., Vasconcelos, J., Riddell, A. & Hykin, P., 11 Nov 2017, In: The Lancet. 390, 10108, p. 2141-2142 2 p.

    Research output: Contribution to journalLetterpeer-review

  27. Safety and patient response as indicated by biomarker changes to binding immunoglobulin protein in the phase I/IIA RAGULA clinical trial in rheumatoid arthritis

    Kirkham, B., Chaabo, K., Hall, C., Garrood, T., Mant, T., Allen, E., Vincent, A., Vasconcelos, J. C., Prevost, A. T., Panayi, G. S. & Corrigall, V. M., 1 Nov 2016, In: Rheumatology. 55, 11, p. 1993-2000 8 p.

    Research output: Contribution to journalArticlepeer-review

  28. Effect of Contemporary Bariatric Surgical Procedures on Type 2 Diabetes Remission. A Population-Based Matched Cohort Study

    Gulliford, M. C., Booth, H. P., Reddy, M., Charlton, J., Fildes, A., Prevost, A. T., Khan, O. & King’s Bariatric Surgery Study Group, Oct 2016, In: OBESITY SURGERY. 26, p. 2308–2315

    Research output: Contribution to journalArticlepeer-review

  29. A randomised controlled trial of three very brief interventions for physical activity in primary care

    Pears, S., Bijker, M., Morton, K., Vasconcelos, J., Parker, R. A., Westgate, K., Brage, S., Wilson, E., Prevost, A. T., Kinmonth, A. L., Griffin, S., Sutton, S. & Hardeman, W., 30 Sep 2016, In: BMC Public Health. 16, 1, p. 1-13 13 p., 1033.

    Research output: Contribution to journalArticlepeer-review

  30. Changing Epidemiology of Bariatric Surgery in the UK: Cohort Study Using Primary Care Electronic Health Records

    Booth, H. P., Khan, O., Fildes, A., Prevost, A. T., Reddy, M., Charlton, J. & Gulliford, M. C., Aug 2016, In: OBESITY SURGERY. 26, p. 1900–1905 6 p.

    Research output: Contribution to journalArticlepeer-review

  31. The clinical and cost effectiveness of a Breathlessness Intervention Service for patients with advanced non-malignant disease and their informal carers: Mixed findings of a mixed method randomised controlled trial

    Farquhar, M. C., Prevost, A. T., McCrone, P., Brafman-Price, B., Bentley, A., Higginson, I. J., Todd, C. J. & Booth, S., 4 Apr 2016, In: Trials. 17, 1, p. 185 185.

    Research output: Contribution to journalArticlepeer-review

  32. The impact of communicating genetic risks of disease on riskreducing health behaviour: Systematic review with meta-analysis

    Hollands, G. J., French, D. P., Griffin, S. J., Prevost, A. T., Sutton, S., King, S. & Marteau, T. M., 15 Mar 2016, In: BMJ (Online). 352, i1102.

    Research output: Contribution to journalArticlepeer-review

  33. A randomized clinical trial comparing fixed vs pro-re-nata dosing of Ozurdex in refractory diabetic macular oedema (OZDRY study)

    Ramu, J., Yang, Y., Menon, G., Bailey, C., Narendran, N., Bunce, C., Quartilho, A., Prevost, A. T., Hykin, P. & Sivaprasad, S., 1 Dec 2015, In: Eye (London, England). 29, 12, p. 1603-1612 10 p.

    Research output: Contribution to journalArticlepeer-review

  34. Fildes et al. Respond

    Fildes, A., Charlton, J., Rudisill, C., Littlejohns, P., Prevost, T. & Gulliford, M. C., Nov 2015, In: American Journal of Public Health. 105, 11, p. e3-4

    Research output: Contribution to journalArticlepeer-review

  35. Clinical efficacy and mechanistic evaluation of aflibercept for proliferative diabetic retinopathy (acronym CLARITY): A multicentre phase IIb randomised active-controlled clinical trial

    Sivaprasad, S., Prevost, A. T., Bainbridge, J., Edwards, R. T., Hopkins, D., Kelly, J., Luthert, P., Murphy, C., Ramu, J., Sarafraz-Shekary, N., Vasconcelos, J., White-Alao, B. & Hykin, P., 14 Aug 2015, In: BMJ Open. 5, 9, e008405.

    Research output: Contribution to journalArticlepeer-review

  36. Correcting for bias in the selection and validation of informative diagnostic tests

    Robertson, D. S., Prevost, A. T. & Bowden, J., 15 Apr 2015, In: Statistics in Medicine. 34, 8, p. 1417-1437

    Research output: Contribution to journalArticlepeer-review

  37. Impact of Community Based Peer Support in Type 2 Diabetes: A Cluster Randomised Controlled Trial of Individual and/or Group Approaches

    Simmons, D., Prevost, A. T., Bunn, C., Holman, D., Parker, R., Cohn, S., Donald, S., Paddison, C., Ward, C., Robbins, P. & Graffy, J., 18 Mar 2015, In: PLOS One. 10, 3, 13 p., e0120277.

    Research output: Contribution to journalArticlepeer-review

  38. Impact of bariatric surgery on clinical depression. Interrupted time series study with matched controls

    Booth, H., Khan, O., Prevost, A. T., Reddy, M., Charlton, J., Gulliford, M. C. & King׳s Bariatric Surgery Study Group, 15 Mar 2015, In: Journal of Affective Disorders. 174, p. 644-649 6 p.

    Research output: Contribution to journalArticlepeer-review

  39. Long-term effect of population screening for diabetes on cardiovascular morbidity, self-rated health, and health behavior

    Echouffo-Tcheugui, J. B., Simmons, R. K., Prevost, A. T., Williams, K. M., Kinmonth, A-L., Wareham, N. J. & Griffin, S. J., Mar 2015, In: ANNALS OF FAMILY MEDICINE. 13, 2, p. 149-157 9 p.

    Research output: Contribution to journalArticlepeer-review

  40. Which Behavior Change Techniques are Associated with Changes in Physical Activity, Diet and Body Mass Index in People with Recently Diagnosed Diabetes?

    Hankonen, N., Sutton, S., Prevost, A. T., Simmons, R. K., Griffin, S. J., Kinmonth, A. L. & Hardeman, W., 1 Feb 2015, In: Annals of Behavioral Medicine. 49, 1, p. 7-17 11 p.

    Research output: Contribution to journalArticlepeer-review

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